• Title/Summary/Keyword: Global stability

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Development of Reverse Transcriptase Polymerase Chain Reaction Primer Sets and Standard Positive Control Capable of Verifying False Positive for the Detection of Severe acute respiratory syndrome coronavirus 2

  • Cho, Kyu Bong
    • Biomedical Science Letters
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    • v.27 no.4
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    • pp.283-290
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    • 2021
  • Severe acute respiratory syndrome coronavirus (SARS-CoV2) is a major coronavirus that infects humans with human Coronavirus (HuCoV)-229E, HCoV-OC43, HCoV-HKU1, HCoV-NL63, Severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle east respiratory syndrome coronavirus (MERS-CoV). SARS-CoV2 is currently a global pandemic pathogen. In this study, we developed conventional RT-PCR based diagnostic system for the detection of SARS-CoV2 which is relatively inexpensive but has high stability and a wide range of users. Three conventional RT-PCR primer sets capable of forming specific band sizes by targeting the ORF1ab [232 nucleotide (nt)], E (200 nt) and N (288 nt) genes of SARS-CoV2 were developed, respectively, and it were confirmed to be about 10~100 times higher detection sensitivity than the previously reported methods. In addition, a standard positive control that can generate specific amplicons by reacting with the developed RT-PCR primers and verify the false-positiv from contamination of the laboratory was produced. Therefore, the diagnostic system that uses the RT-PCR method is expected to be used to detect SARS-CoV2.

A Study on the Development and Verification of a Korean-style Weekly Economic Activity Index(WEAI) Model in the Public Sector: By Analyzing Major Cases (공공부문 한국형 주간경제지수 모델 개발 및 검증에 관한 연구: 주요사례를 분석하여)

  • Song, Seokhyun
    • Journal of Information Technology Services
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    • v.20 no.5
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    • pp.177-187
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    • 2021
  • The global economy has been very difficult due to the recent impact of COVID-19. Korea is also pushing for strong quarantine policies such as K- quarantine and social distancing, but the economy is hardly recovering. In particular, the economic situation began to change rapidly depending on the export and domestic market, the public's interest in the economy increased, and companies became more sensitive. In order to estimate this rapidly changing economic situation, major advanced countries have also developed models that can periodically monitor the economy at the government level. Through this, by periodically reporting the economic trends, the public and companies can be aware of the economic trends to some extent. This study analyzed the cases of weekly business trends in advanced countries and developed a model of weekly economic activity suitable for Korea. To verify this, indices closely related to the economy such as mobility, industrial activity, face-to-face consumption, and psychology were discovered and estimated. As a result of the study, the weekly economic activity index was judged to be very useful in capturing short-term real economic activity. In the future, in order to secure the robustness and stability of the index and to increase the reflection of reality, model improvement and parameter estimation should be performed regularly.

Development of Computational Tools for Seismic Design of Architectural Components in Negative Pressure Isolation Wards (음압격리병동의 건축 비구조요소 내진설계를 위한 전산도구 개발)

  • Chu, Yu Rim;Kim, Tae Jin
    • Journal of the Earthquake Engineering Society of Korea
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    • v.26 no.3
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    • pp.127-136
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    • 2022
  • Recently, an unprecedented emerging infectious disease has rapidly spread, causing a global shortage of wards. Although various temporary beds have appeared, the supply of wards specializing in infectious diseases is required. Negative pressure isolation wards should maintain their function even after an earthquake. However, the current seismic design standards do not guarantee the negative pressure isolation wards' operational (OP) performance level. For this reason, some are not included in the design target even though they are non-structural elements that require seismic design. Also, the details of non-structural elements are usually determined during the construction phase. It is often necessary to complete the stability review and reinforcement design for non-structural elements within a short period. Against this background, enhanced performance objectives were set to guarantee the OP non-structural performance level, and a computerized tool was developed to quickly perform the seismic design of non-structural elements in the negative pressure isolation wards. This study created a spreadsheet-based computer tool that reflects the components, installation spacing, and design procedures of non-structural elements. Seismic performance review and design of the example non-structural elements were conducted using the computerized tool. The strength of some components was not sufficient, and it was reinforced. As a result, the time and effort required for strength evaluation, displacement evaluation, and reinforcement design were reduced through computerized tools.

Design and Implementation of 3-Axis Control System using The Non-Linear Algorithm (비선형 알고리즘을 이용한 3축 제어 시스템의 설계 및 제작)

  • Cho, Byeong-Gwan;Lee, Hwan-Hee;Choi, Woo-Jin;Kim, Yu-Gi;Lee, Seung-Dae
    • The Journal of the Korea institute of electronic communication sciences
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    • v.17 no.5
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    • pp.833-840
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    • 2022
  • The precision of automation equipment and motors in factories is required, and global motor market has increased significantly. However, domestic motor technology lags behind foreign technology. In this thesis, the precision stability and efficiency were compared with a linear algorithm by applying a non-linear algorithm to a PLC servo motor and an Arduino step motor in order to improve the technology of the motor. The nonlinear algorithm was able to shorten the same driving reference time because the maximum speed of the motor was faster than the linear algorithm, and it was confirmed that the precision was improved due to the low curvature.

Basic Study on the Improvement of Material Removal Efficiency of Sapphire CMP Using Electrolytic Ionization and Ultraviolet Light (전해 이온화와 자외선광을 이용한 사파이어 화학기계적 연마의 재료제거 효율 향상에 관한 기초 연구)

  • Park, Seonghyun;Lee, Hyunseop
    • Tribology and Lubricants
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    • v.37 no.6
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    • pp.208-212
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    • 2021
  • Chemical mechanical polishing (CMP) is a key technology used for the global planarization of thin films in semiconductor production and smoothing the surface of substrate materials. CMP is a type of hybrid process using a material removal mechanism that forms a chemically reacted layer on the surface of a material owing to chemical elements included in a slurry and mechanically removes the chemically reacted layer using abrasive particles. Sapphire is known as a material that requires considerable time to remove materials through CMP owing to its high hardness and chemical stability. This study introduces a technology using electrolytic ionization and ultraviolet (UV) light in sapphire CMP and compares it with the existing CMP method from the perspective of the material removal rate (MRR). The technology proposed in the study experimentally confirms that the MRR of sapphire CMP can be increased by approximately 29.9, which is judged as a result of the generation of hydroxyl radicals (·OH) in the slurry. In the future, studies from various perspectives, such as the material removal mechanism and surface chemical reaction analysis of CMP technology using electrolytic ionization and UV, are required, and a tribological approach is also required to understand the mechanical removal of chemically reacted layers.

On the Inflation and its Modifications in the Era of Global Pandemic: The Case of Some ADB Countries

  • CHARAIA, Vakhtang;PAPAVA, Vladimer
    • The Journal of Asian Finance, Economics and Business
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    • v.9 no.8
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    • pp.7-17
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    • 2022
  • The article discusses the problems caused by inflation in the developing Asia-Pacific region during the time of the worldwide pandemic and suggests innovative solutions to the problem. The reality is that some of the commodity groups from the consumer basket (e.g., non-seasonal fruits, electronics, furniture, hotel, and restaurant services, etc.) fail to reflect the needs of the low-income earners, which make the majority in developing countries. At the same time, the inflation targeting regime has become outdated and not reliable, because of uncontrolled exogenic factors (imported inflation, fluctuation in oil prices, supply chain disruption, Russia-Ukraine war, etc.) prevailing on endogenic factors and thus making it impossible to control the price stability, especially in developing countries. Since, the old-fashioned inflation index and inflation targeting mechanisms regrettably fail to fully reflect both the society and governmental/central banks' expectations, based on which we first should have better care and second create better policies; we propose to use a combination of already well-known indexes and policies, with the new statistical indicators, which reflects price fluctuations on the medication, utilities, and nutrition.

Numerical Study on the NH3/CH4 Symmetric Premixed Counterflow Flames - Part I Characteristics of Extinction Behavior (암모니아/메탄 예혼합 대향류 대칭화염에 관한 수치해석적 연구 - Part I 소화거동의 특성)

  • EUNSEO JIN;KEEMAN LEE
    • Journal of Hydrogen and New Energy
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    • v.34 no.1
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    • pp.47-58
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    • 2023
  • Experimental data conducted by Colson et al. and numerical data conducted in this study were compared through counterflow flames to understand of the characteristic of basic flame about mixture of ammonia/methane. In order to use the suitable numerical mechanism, the validation was performed using total four mechanisms and the Okafor's mechanism showed satisfactory experimental results. The extinction boundary of the stability map could be explained through the effective Lewis number and the trend of LeD. The extinction behavior of the flame was different under the lean and rich symmetric conditions and it was investigated by the major variables, global strain rate (ag) and mole fraction of ammonia (ΩNH3).

A Study on the Restructuring Global Production Space of Korean Rechargeable Battery Companies (한국 이차전지기업의 글로벌 생산공간 재구성 연구)

  • Ja-Yeong Choe
    • Journal of the Economic Geographical Society of Korea
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    • v.25 no.4
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    • pp.499-513
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    • 2022
  • This study targets the rechargeable battery industry, which has been rapidly growing recently. The rechargeable battery industry is closely related to the electric vehicle industry. However, other factors also influence it. Currently, rechargeable battery companies show a pattern of restructuring production space by various means. To determine the causes of these production spaces, the factors affecting regional and national scales were thoroughly examined. As a result, the location factors for rechargeable battery-related companies are determined by cooperative relationships with assembled car companies, government policy regulations, and the stability of supply of key materials. And a spatial strategy was implemented to make the most of these circumstances.

A Comparison of Dynamic Analysis for the Flexible Riser in Shallow Water (천해에서 유연라이저의 동적해석 결과 비교)

  • Jo, Chul-Hee;Kim, Do-Youb;Rho, Yu-Ho;Kim, In-Ho
    • Journal of Coastal Disaster Prevention
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    • v.1 no.4
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    • pp.149-155
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    • 2014
  • Flexible risers have been used extensively in recent years for floating and early production systems. Such risers offer the advantage of having inherent heave compliance in their catenary thereby greatly reducing the complexity of the riser-to-rig and riser-to subsea interfaces. Another advantage with flexible risers is their greater reliability. Concerns about fatigue life, gas permeation and pigging of lines have been overcome by extensive experience with these risers in production applications. In this paper, flexible riser analysis results were compared through coupled and uncoupled dynamic analyses methods. A time domain coupled analysis capability has been developed to model the dynamic responses of an integrated floating system incorporating the interactions between vessel, moorings and risers in a marine environment. For this study, SPM (Single Point Mooring) system for an FSU in shallow water was considered. This optimization model was integrated with a time-domain global motion analysis to assess both stability and design constraints of the flexible riser system.