• Title/Summary/Keyword: Genetic Approach

Search Result 1,327, Processing Time 0.024 seconds

Universal and Can be Applied Wireless Channel Assignment Algorithm (범용 적용이 가능한 무선채널할당알고리즘)

  • Heo, Seo-Jung;Son, Dong-Cheul;Kim, Chang-Suk
    • Journal of Digital Convergence
    • /
    • v.10 no.9
    • /
    • pp.375-381
    • /
    • 2012
  • If a mobile station requests a channel allocation in its mobile networks, the switching center assigns a channel to a mobile station that belongs to each base station. There are three kinds of channel allocation schemes; a fixed channel allocation, a dynamic channel allocation and a hybrid combination of these two forms. In assigning a good frequency, it is our intention to provide quality service to our customers as well as to use resources efficiently. This paper proposes methods of assigning frequencies that minimize interference between channels and that also minimize the amount of searching time involved. In this paper, we propose an algorithm to per specific equipment, regardless of the number of channels that can be used as a general-purpose system, such as base stations, control stations, central office model is proposed, the existing operators manner similar to the fixed channel allocation based statistics and assigned when the conventional method and the improved method is proposed. Different ways and compared via simulations to verify the effectiveness of the proposed approach.

The Min-Distance Max-Quantity Assignment Algorithm for Random Type Quadratic Assignment Problem (랜덤형 2차원 할당문제의 최소 거리-최대 물동량 배정 알고리즘)

  • Lee, Sang-Un
    • The Journal of the Institute of Internet, Broadcasting and Communication
    • /
    • v.18 no.3
    • /
    • pp.201-207
    • /
    • 2018
  • There is no known polynomial time algorithm for random-type quadratic assignment problem(RQAP) that is a NP-complete problem. Therefore the heuristic or meta-heuristic approach are solve the approximated solution for the RQAP within polynomial time. This paper suggests polynomial time algorithm for random type quadratic assignment problem (QAP) with time complexity of $O(n^2)$. The proposed algorithm applies one-to-one matching strategy between ascending order of sum of distance for each location and descending order of sum of quantity for each facility. Then, swap the facilities for reflect the correlation of distances of locations and quantities of facilities. For the experimental data, this algorithm, in spite of $O(n^2)$ polynomial time algorithm, can be improve the solution than genetic algorithm a kind of metaheuristic method.

Electrophysiological characteristics of R47W and A298T mutations in CLC-1 of myotonia congenita patients and evaluation of clinical features

  • Chin, Hyung Jin;Kim, Chan Hyeong;Ha, Kotdaji;Shin, Jin Hong;Kim, Dae-Seong;So, Insuk
    • The Korean Journal of Physiology and Pharmacology
    • /
    • v.21 no.4
    • /
    • pp.439-447
    • /
    • 2017
  • Myotonia congenita (MC) is a genetic disease that displays impaired relaxation of skeletal muscle and muscle hypertrophy. This disease is mainly caused by mutations of CLCN1 that encodes human skeletal muscle chloride channel (CLC-1). CLC-1 is a voltage gated chloride channel that activates upon depolarizing potentials and play a major role in stabilization of resting membrane potentials in skeletal muscle. In this study, we report 4 unrelated Korean patients diagnosed with myotonia congenita and their clinical features. Sequence analysis of all coding regions of the patients was performed and mutation, R47W and A298T, was commonly identified. The patients commonly displayed transient muscle weakness and only one patient was diagnosed with autosomal dominant type of myotonia congenita. To investigate the pathological role of the mutation, electrophysiological analysis was also performed in HEK 293 cells transiently expressing homo-or heterodimeric mutant channels. The mutant channels displayed reduced chloride current density and altered channel gating. However, the effect of A298T on channel gating was reduced with the presence of R47W in the same allele. This analysis suggests that impaired CLC-1 channel function can cause myotonia congenita and that R47W has a protective effect on A298T in relation to channel gating. Our results provide clinical features of Korean myotonia congenita patients who have the heterozygous mutation and reveal underlying pathophyological consequences of the mutants by taking electrophysiological approach.

Next Generation Dairy Processing Science and Technology: Functional and Rational in Dairy Industry

  • Charchoghlyan, Haykuhi
    • Journal of Dairy Science and Biotechnology
    • /
    • v.33 no.3
    • /
    • pp.167-170
    • /
    • 2015
  • The dairy industry, as part of the broader agricultural sector, is classified as a basic industry to the Korea economy. Basic industries provide income to a region by producing an output, purchasing production inputs, services and labor. An integrated, multidisciplinary approach for the next generation of dairy products with added health benefits represent the direct economic contribution. The commercialization of "nutritional" functional foods can only be successful if the consumer is confident in the scientific validity of the claims. Modern biotechnologies such as genomics, genetic expression and biomarkers of health performance suggested to whole dairy products, such as fluid milk, butter, cheese, ice cream and frozen dessert products (German, 1999). The following definition makes the point that dairy products can provide a nutritional value beyond the basic nutritional requirements: 1) The dairy industry has the opportunity to improve the health and well-being of its customers and/or to reduce their risk of disease through dairy products with added activities. 2) Functional dairy products are those that can be demonstrated to benefit target functions in the body in a way that improves the state of health and /or reduces the risk of disease. They are food products that are consumed as part of a normal diet rather than pills or supplements. 3) Dairy products based on functionality will need to link the scientific basis of such functionality to the communication of its benefit to the general public. 4) Both the efficacy and the safety of the food components with health benefits will require evidence based on the measurement of scientific biomarkers relevant to their biological responses and health end points. 5) Sound evidence from human studies based on intermediate health end points using accepted biomarkers will provide the basis for promotional messages divided into two categories-enhanced function and reduced risk of disease. 6) Success in solving key scientific and technological challenges will only be achieved by interdisciplinary research programs to exploit the scientific concepts in functional dairy science.

  • PDF

Statistical Information-Based Hierarchical Fuzzy-Rough Classification Approach (통계적 정보기반 계층적 퍼지-러프 분류기법)

  • Son, Chang-S.;Seo, Suk-T.;Chung, Hwan-M.;Kwon, Soon-H.
    • Journal of the Korean Institute of Intelligent Systems
    • /
    • v.17 no.6
    • /
    • pp.792-798
    • /
    • 2007
  • In this paper, we propose a hierarchical fuzzy-rough classification method based on statistical information for maximizing the performance of pattern classification and reducing the number of rules without learning approaches such as neural network, genetic algorithm. In the proposed method, statistical information is used for extracting the partition intervals of antecedent fuzzy sets at each layer on hierarchical fuzzy-rough classification systems and rough sets are used for minimizing the number of fuzzy if-then rules which are associated with the partition intervals extracted by statistical information. To show the effectiveness of the proposed method, we compared the classification results(e.g. the classification accuracy and the number of rules) of the proposed with those of the conventional methods on the Fisher's IRIS data. From the experimental results, we can confirm the fact that the proposed method considers only statistical information of the given data is similar to the classification performance of the conventional methods.

Hordein Fingerprinting for Cultivar Discrimination in National List of Barley (Hordein 분석을 통한 보리 국가목록등재품종의 품종식별)

  • 소은희;고은별;최수정;이종호;송인호
    • KOREAN JOURNAL OF CROP SCIENCE
    • /
    • v.49 no.3
    • /
    • pp.256-260
    • /
    • 2004
  • A major challenge facing those involved in the testing of new plant varieties for distinctness, uniformity and stability (DUS) is the need to compare new varieties against all those of common knowlege (reference varieties). One possible approach would be to group new (candidate) varieties and reference varieties using descriptions stored in databases prior to further of official test. testing. This study was carried out to manage a reference variety collection by databasing of hordein profiling. For this purpose, hordein subunits of the 48 National list barley (Hordeum vulgare L) cultivars were analysed. Total 22 of clear scorable hordein subunits were identified from D-subunit to B-subunit region and fifteen different hordein polypeptide patterns were obtained. Based on hordein subunit band pattern, UPGMA cluster analysis was conducted. Forty-eight cultivars were separated into three groups and genetic distance of cluster ranging from 0.55 to 1.00. Hordein subunits have a potential of selecting similar varieties compared with candidate varieties by controlling reference variety collection and playing an important complemental role in cultivar distinctness.

Shifting reproductive mode of a mycotoxin producing-fungus by manipulation of mating-type genes

  • Lee, Jungkwan;Lee, Teresa;Lee, Yin-Won;Yun, Sung-Hwan;Gillian Turgeon
    • Proceedings of the Korean Society of Plant Pathology Conference
    • /
    • 2003.10a
    • /
    • pp.85.1-85
    • /
    • 2003
  • In most ascomycetes, a single mating type locus, MAT, with two alternate forms (MAT1-1 and MAT1-2) called idiomorphs, controls mating ability. In heterothallic ascomycetes these alternate idiomorphs reside in different nuclei. In contrast, most homothallic ascomycetes carry both MAT1-1 and MAT1-2 in a single nucleus, usually closely linked. An example of the latter is Gibberella zeae, a producer of mycotoxins such as trichothecene and zearalenone that threaten human and animal health. We asked if G. zeae could be made strictly heterothallic by manipulation of MAT. Targeted gene replacement was used to differentially delete MAT1-1 or MAT1-2 from a wild type haploid MAT1-1 MAT1-2 strain, resulting in MAT1-1;mat1-2, mat1-1;MAT1-2 strains that were self-sterile, yet able to cross to wild type testers and more importantly, to each other. These results indicated that differential deletion of MAT idiomorphs eliminates selfing ability of G. zeae, but the ability to outcross is retained. To our knowledge, this is the first report of complete conversion of fungal reproductive strategy from homothallic to heterothallic by targeted manipulation of MAT. Practically, this approach opens the door to simple and efficient procedures for obtaining sexual recombinants of G. zeae that will be useful for genetic analyses of mycotoxin production and other traits, such as ability to cause disease.

  • PDF

A Study on Teaching of the Elements of Geometry in Secondary School (중학교 기하 교재의 '원론' 교육적 고찰)

  • Woo Jeong-Ho;Kwon Seok-Il
    • Journal of Educational Research in Mathematics
    • /
    • v.16 no.1
    • /
    • pp.1-23
    • /
    • 2006
  • It is regarded as critical to analyse and re-appreciate Euclidean geometry for the sake of improving school geometry This study, a critical analysis of demonstrative plane geometry in current secondary school mathematics with an eye to the viewpoints of 'Elements of Geometry', is conducted with this purpose in mind. Firstly, the 'Elements' is analysed in terms of its educational purpose, concrete contents and approaching method, with a review of the history of its teaching. Secondly, the 'Elemens de Geometrie' by Clairaut and the 'histo-genetic approach' in teaching geometry, mainly the one proposed by Branford, are analysed. Thirdly, the basic assumption, contents and structure of the current textbooks taught in secondary schools are analysed according to the hypothetical construction, ordering and grouping of theorems, presentations of proofs, statements of definitions and exercises. The change of the development of contents over time is also reviewed, with a focus on the proportional relations of geometric figures. Lastly, tile complementary way of integrating the two 'Elements' is explored.

  • PDF

A PRESERVATIVE APPROACH TO PREVENTION OF SELF-MUTILATION IN PATIENT WITH LESCH-NYHAN SYNDROME ; A CASE REPORT (Lesch-Nyhan 증후군 환아의 자해 예방을 위한 보존적 접근 : 증례보고)

  • Kang, Dong-Gyun;Kim, Tae-Wan;Kim, Young-Jin
    • The Journal of Korea Assosiation for Disability and Oral Health
    • /
    • v.2 no.2
    • /
    • pp.147-152
    • /
    • 2006
  • Lesch-Nyhan syndrome is rare X-linked genetic disorder involving absence of the enzyme hypoxanthine guanine phosphoribosyl transferase (HGPRT) related to purine metabolism. The deficiency of HGPRT activity leads to an excesscive uric acid production and consequent hyperuricemia. It occurs almost exclusively in males, and the incidence is estimate to be 1/100,000~380,000. Clinical presentation is characterized by developmental delay, mental retardation, choreoathetosis, spastic cerebral palsy, nephrolithiasis, obstructive nephropathy and acute gouty arthritis. A characteristic feature of Lesch-Nyhan syndrome is the appearance of intractable self-mutilation behavior. Self-mutilation behavior is complicated by secondary infection and tissue loss as well as pain. The dental management of self-mutilation includes presertive methods of using appliances such as lip bumper or soft mouthguard and radical methods such as extraction of all teeth or orthognathic surgery. A case of Lesch-Nyhan syndrome patient with self-mutilation and severe lower lip injury is presented. He was treated successfully with soft mouthguard.

  • PDF

Assessment through Statistical Methods of Water Quality Parameters(WQPs) in the Han River in Korea

  • Kim, Jae Hyoun
    • Journal of Environmental Health Sciences
    • /
    • v.41 no.2
    • /
    • pp.90-101
    • /
    • 2015
  • Objective: This study was conducted to develop a chemical oxygen demand (COD) regression model using water quality monitoring data (January, 2014) obtained from the Han River auto-monitoring stations. Methods: Surface water quality data at 198 sampling stations along the six major areas were assembled and analyzed to determine the spatial distribution and clustering of monitoring stations based on 18 WQPs and regression modeling using selected parameters. Statistical techniques, including combined genetic algorithm-multiple linear regression (GA-MLR), cluster analysis (CA) and principal component analysis (PCA) were used to build a COD model using water quality data. Results: A best GA-MLR model facilitated computing the WQPs for a 5-descriptor COD model with satisfactory statistical results ($r^2=92.64$,$Q{^2}_{LOO}=91.45$,$Q{^2}_{Ext}=88.17$). This approach includes variable selection of the WQPs in order to find the most important factors affecting water quality. Additionally, ordination techniques like PCA and CA were used to classify monitoring stations. The biplot based on the first two principal components (PCs) of the PCA model identified three distinct groups of stations, but also differs with respect to the correlation with WQPs, which enables better interpretation of the water quality characteristics at particular stations as of January 2014. Conclusion: This data analysis procedure appears to provide an efficient means of modelling water quality by interpreting and defining its most essential variables, such as TOC and BOD. The water parameters selected in a COD model as most important in contributing to environmental health and water pollution can be utilized for the application of water quality management strategies. At present, the river is under threat of anthropogenic disturbances during festival periods, especially at upstream areas.