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The Usefulness of Q.Clear Technique in PET / CT (PET/CT 검사에서 Q.Clear 기법의 유용성에 대한 고찰)

  • Choi, Yong Hoon;Kim, Jung Yul;Choi, Young Sook;Lim, Han Sang;Kim, Jae Sam
    • The Korean Journal of Nuclear Medicine Technology
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    • v.21 no.2
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    • pp.31-36
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    • 2017
  • Purpose Recently, the performance of PET/CT scanner has been improved and various techniques have been developed to increase the image quality such as Sensitivity and Resolution. The purpose of this study is to evaluate the usefulness of Q.Clear (a fully convergent iterative reconstruction) technique of GE Discovery IQ equipment to enhance the image quality. Materials and Methods All scans were acquired by Discovery IQ (GE Healthcare, MI, USA). In NEMA IEC Body Phantom test, Background to Hot-sphere (10 mm, 13 mm, 17 mm, 22 mm) ratio was 1:4 and scan time was 3 minutes. The images were reconstructed by VPHDs (VUE Point High-Definition + SharpIR) and Q.Clear to evaluate each Contrast. We injected 18F-FDG 187 M㏃ to PET/SPECT Performance Phantom. And then it was scanned for 4 minutes to evaluate Resolution and Uniformity. T-test statistical analysis was performed on SUVmax of small lesions less than 2 cm in 100 clinical patients regardless of disease type. Results In the NEMA IEC Body Phantom, the Contrast was $63.6{\pm}5.7%$ (VPHDs) and $75{\pm}4.8%$ (Q.Clear). In the PET/SPECT Performance Phantom, the Resolution was 9.2 mm (VPHDs) and 7.3 mm (Q.Clear). Uniformity of Q.Clear was 10.8% better than VPHDs. T-test statistic of the clinical patients showed a significant difference of p value of 0.021. Conclusion Both the phantom test and the clinical results showed that the quality of the image was improved in Q.Clear was applied. The SUVmax was highly measured in Q.Clear and the lesions were clearly distinguished visually. Therefore Q.Clear can be useful in various aspects such as dose-reduction, patients evaluation and image analysis.

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The Comparison Evaluation of SUV Using Different CT Devices in PET/CT Scans (PET 검사에서 CT 장비의 차이에 따른 PET/CT의 SUV 비교 평가)

  • Kim, Woo Hyun;Go, Hyeon Soo;Lee, Jeong Eun;Kim, Ho Sung;Ryu, Jae Kwang;Jung, Woo Young
    • The Korean Journal of Nuclear Medicine Technology
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    • v.18 no.1
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    • pp.10-18
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    • 2014
  • Purpose: Among different PET/CT devices which are composed of same PET model but different CT models, SUV, usually used for quantitative evaluation, was measured to assess the accuracy of follow up scans in different PET/CT and confirm that interequipment compatibility is useful in arranging the PET/CT exam appointment. Materials and Methods: Using ACR PET Phantom, PET NEMA IEC Body Phantom, SNM Chest Phantom and Ge-68 cylinder Phantom, $SUV_{mean}$ and $SUV_{max}$ was measured by 3 different models of PET/CT (Discovery 690, Discovery 690Elite and Discovery 710, GE) made in same company. ANOVA was used to evaluate the significant difference in the result. Results: In the result, the average of $SUV_{max}$ was D690 (25 mm-1.82, 16 mm-1.75, 12 mm-1.73, 8 mm-1.44), D690E (25 mm-1.76, 16 mm-1.92, 12 mm-1.78, 8 mm-1.55) and D710 (25 mm-1.84, 16 mm-1.89, 12 mm-1.77, 8 mm-1.61) in ACR Phantom, D690 (25 mm-2.26, 16 mm-2.25, 12 mm-1.92, 8 mm-1.85), D690E (25 mm-2.45, 16 mm-2.25, 12 mm-2.05 8 mm-1.91) and D710(25 mm-2.49, 16 mm-2.20, 1 2mm-2.30, 8 mm-2.05) in PET NEMA IEC Body Phantom, D690-1.04, D690E-1.10 and D710-1.09 in SNM Chest Phantom and D690-0.81, D690E-0.81, D710-0.84 in Ge-68 cylinder Phantom. The differences between average SUV of 4 phantoms were $SUV_{mean}$-1.87%, $SUV_{max}$-2.15%. And also as a result of ANOVA analysis, there was no significant difference statistically. Conclusion: If different models of PET/CT have same specification of PET system, there was no significant difference in $SUV_{mean}$ and $SUV_{max}$ even though they have different CT system. And also differences of $SUV_{mean}$ and $SUV_{max}$ in phantom images were under 5% which many manufacturers recommend. Therefore, follow up scan will be possible using different PET/CT if it has same specification of PET system with the previous PET/CT. This information will enable the accurate comparative analysis when conducting follow up scans and be helpful to schedule PET/CT exam more effectively.

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A Study on the Change of Image Quality According to the Change of Tube Voltage in Computed Tomography Pediatric Chest Examination (전산화단층촬영 소아 흉부검사에서 관전압의 변화에 따른 화질변화에 관한 연구)

  • Kim, Gu;Kim, Gyeong Rip;Sung, Soon Ki;Kwak, Jong Hyeok
    • Journal of the Korean Society of Radiology
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    • v.13 no.4
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    • pp.503-508
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    • 2019
  • In short a binary value according to a change in the tube voltage by using one of VOLUME AXIAL MODE of scanning techniques of chest CT image quality evaluation in order to obtain high image and to present the appropriate tube voltage. CT instruments were GE Revolution (GE Healthcare, Wisconsin USA) model and Phantom used Pediatric Whole Body Phantom PBU-70. The test method was examined in Volume Axial mode using the pediatric protocol used in the Y university hospital of mass-produced material. The tube voltage was set to 70kvp, 80kvp, 100kvp, and mAs was set to smart mA-ODM. The mean SNR difference of the heart was $-4.53{\pm}0.26$ at 70 kvp, $-3.34{\pm}0.18$ at 80 kvp, $-1.87{\pm}0.15$ at 100 kvp, and SNR at 70 kvp was about -2.66 higher than 100 kvp and statistically significant (p<0.05) In the Lung SNR mean difference analysis, $-78.20{\pm}4.16$ at 70 kvp, $-79.10{\pm}4.39$ at 80 kvp, $-77.43{\pm}4.72$ at 100 kvp, and SNR at 70 kvp at about -0.77 higher than 100 kvp were statistically significant. (p<0.05). Lung CNR mean difference was $73.67{\pm}3.95$ at 70 kvp, $75.76{\pm}4.25$ at 80 kvp, $75.57{\pm}4.62$ at 100 kvp and 20.9 CNR at 80 kvp higher than 70 kvp and statistically significant (p<0.05) At 100 kvp of tube voltage, the SNR was close to 1 while maintaining the quality of the heart image when 70 kvp and 80 kvp were compared. However, there is no difference in SNR between 70 kvp and 80 kvp, and 70 kvp can be used to reduce the radiation dose. On the other and, CNR showed an approximate value of 1 at 70 kvp. There is no difference between 80 kvp and 100 kvp. Therefore, 80 kvp can reduce the radiation dose by pediatric chest CT. In addition, it is possible to perform a scan with a short scan time of 0.3 seconds in the volume axial mode test, which is useful for pediatric patients who need to move or relax.

A Comparative Study of Production of [68Ga]PSMA-11 with or without Cassette Type Modules (비 카세트 방식과 카세트 방식을 이용한 [68Ga]PSMA-11의 자동 합성 방법 비교)

  • Hyun-Sik, Park;Byeong-Min, Jo;Hyun-Ho, An;Hong-Jin, Lee;Jin-Hyeong, Lee;Gyeong-Jae, Lee;Byung-Chul, Lee;Won-Woo, Lee
    • The Korean Journal of Nuclear Medicine Technology
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    • v.26 no.2
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    • pp.15-19
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    • 2022
  • Purpose [68Ga]PSMA-11 is needed the high reproducibility, excellent radiochemical yield and purity. In term of radiation safety, the radiation exposure of operator for its production also should be considered. In this work, we performed a comparative study for the fully automated synthesis of [68Ga]PSMA-11 between non-cassette type and cassette type. Materials and Methods Two different type of modules (TRACERlab FX N pro for non-cassette type and BIKBox for cassette type) were used for the automated production of [68Ga]PSMA-11. According to the previously identified elution profile, Only 2.5 ml with high radioactivity was used for the reaction. After adjusting the pH of the reaction solution with HEPES buffer solution, the precursor was added and reacted with at 95 ℃ for 15 minutes. The reaction mixture was separated and purified using a C18 light cartridge. The product was eluted with 50% EtOH/saline solution and diluted with saline. It was completed by sterilizing filter. In the non-cassette type, the aforementioned process must be prepared directly. However, in the cassette method, synthesis was possible simply by installing a kit that was already completed. Results Both total [68Ga]PSMA-11 production time were 25±3(non-cassette type) and 23±3 minutes(cassette type). The radiochemical yield of the non-cassette type(65.5±5.7%) was higher than that of the cassette type(61.6±4.8%) after sterilization filter. The non-cassette type took about 120 minutes of preparation time before synthesis due to washing of synthesizer and reagent preparation. However, since the cassette type does not require washing and reagent preparation, it took about 20 minutes to prepare before synthesis. Both type of synthesizer had a radiochemical high purity(>99%). Conclusion The non-cassette type production of [68Ga]PSMA-11 showed higher radiochemical yield and lower cost than the cassette type. However, The cassette type has an advantage in terms of preparation time, convenience, and equipment maintenance.

A Programmable Compensation Circuit for System-on-Chip Application

  • Choi, Woo-Chang;Ryu, Jee-Youl
    • JSTS:Journal of Semiconductor Technology and Science
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    • v.11 no.3
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    • pp.198-206
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    • 2011
  • This paper presents a new programmable compensation circuit (PCC) for a System-on-Chip (SoC). The PCC is integrated with $0.18-{\mu}m$ BiCMOS SiGe technology. It consists of RF Design-for-Testability (DFT) circuit, Resistor Array Bank (RAB) and digital signal processor (DSP). To verify performance of the PCC we built a 5-GHz low noise amplifier (LNA) with an on-chip RAB using the same technology. Proposed circuit helps it to provide DC output voltages, hence, making the RF system chain automatic. It automatically adjusts performance of an LNA with the processor in the SoC when it goes out of the normal range of operation. The PCC also compensates abnormal operation due to the unusual PVT (Process, Voltage and Thermal) variations in RF circuits.

Comparative Analysis of Consumption Expenditures by Occupation of the Household Head (가구주의 직업유형에 따른 소비지출양식의 비교분석)

  • 최현자
    • Journal of Families and Better Life
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    • v.18 no.1
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    • pp.167-184
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    • 2000
  • This study has investigated the degree of similarities and/or differences of consumption expenditure styles among the households with different occupation. Two types of analysis were performed. One was comparative analysis which used to identify the changes of consumption expenditure styles among different occupation classes using time-series data of 1977-1996 Korean Urban Household Expenditure Survey and Rural Household Economy Survey. The other was multivariate analysis to investigate the effects of occupation on consumption expenditure styles with 1551 sample household data from 1996 Korean Urban Household Expenditure Survey. The results showed that the differences in consumption styles among different occupation classes including farmers are diminished during last two decades while there still exist some degree of differences in consumption styles. After controlling other socio-economic factors it is found that occupation is a determinant of consumption patterns of urban w ge earners especially consumption for clothing and health items.

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A Public-Key Cryptography Processor Supporting GF(p) 224-bit ECC and 2048-bit RSA (GF(p) 224-비트 ECC와 2048-비트 RSA를 지원하는 공개키 암호 프로세서)

  • Sung, Byung-Yoon;Shin, Kyung-Wook
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2018.05a
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    • pp.163-165
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    • 2018
  • GF(p)상 타원곡선 암호(ECC)와 RSA를 단일 하드웨어로 통합하여 구현한 공개키 암호 프로세서를 설계하였다. 설계된 EC-RSA 공개키 암호 프로세서는 NIST 표준에 정의된 소수체 상의 224-비트 타원 곡선 P-224와 2048-비트 키 길이의 RSA를 지원한다. ECC와 RSA가 갖는 연산의 공통점을 기반으로 워드기반 몽고메리 곱셈기와 메모리 블록을 효율적으로 결합하여 최적화된 데이터 패스 구조를 적용하였다. EC-RSA 공개키 암호 프로세서는 Modelsim을 이용한 기능검증을 통하여 정상동작을 확인하였으며, $0.18{\mu}m$ CMOS 셀 라이브러리로 합성한 결과 11,779 GEs와 14-Kbit RAM의 경량 하드웨어로 구현되었다. EC-RSA 공개키 암호 프로세서는 최대 동작주파수 133 MHz이며, ECC 연산에는 867,746 클록주기가 소요되며, RSA 복호화 연산에는 26,149,013 클록주기가 소요된다.

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ECC Processor Supporting Elliptic Curve B-233 over GF(2m) using 32-b WMM (GF(2m) 상의 타원곡선 B-233을 지원하는 32-비트 WMM 기반 ECC 프로세서)

  • Lee, Sang-Hyun;Shin, Kyung-Wook
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2018.05a
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    • pp.169-170
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    • 2018
  • 이진체 상의 타원곡선 B-233을 지원하는 타원곡선 암호 프로세서를 32-비트 워드기반 몽고메리 곱셈기를 이용하여 설계하였다. 스칼라 곱셈을 위해 수정된 몽고메리 래더 (Modified montgomery ladder) 알고리즘을 적용하여 단순 전력분석에 내성을 갖도록 하였으며, Lopez-Dahab 투영 좌표계와 페르마의 소정리(Fermat's little theorem)를 적용하여 하드웨어 자원 소모가 큰 나눗셈과 역원 연산을 제거하여 저면적으로 설계하였다. 설계된 ECC 프로세서는 Xilinx ISim을 이용하여 기능검증을 하였으며, $0.18{\mu}m$ CMOS 셀 라이브러리로 합성한 결과 100 MHz의 동작 주파수에서 9,614 GEs와 4 Kbit RAM으로 구현되었으며, 최대 동작 주파수는 125 MHz로 예측되었다.

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First Record of the Cook's cardinalfish, Apogon cookii (Apogonidae, Perciformes) from Korea (독도연안에서 채집된 한국미기록 어종 다섯줄얼게비늘 (국명신칭, 동갈돔과) Apogon cookii에 대하여)

  • Myoung, Jung-Goo;Cho, Sun-Hyung;Park, Jeong-Ho;Kim, Jong Man
    • Korean Journal of Ichthyology
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    • v.18 no.2
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    • pp.148-150
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    • 2006
  • Two specimens of Apogon cookii of the family Apogonidae were collected from the coastal waters of Dokdo, Korea, and described as the first record from Korea. Specimens were caught by SCUBA diving using scoop net (length 33 cm, depth 63 cm) on October, 1997. The species differs from A. endekataenia in having 5 longitudinal stripes and a small black spot on the base of caudal fin. The new Korean name, "Da-seot-jul-eol-ge-bi-neul" as new Korean name of Apogon cookii.

Development of In vitro Technique for Bioavailable Corn Energy Value

  • Kim, I.B.
    • Asian-Australasian Journal of Animal Sciences
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    • v.14 no.11
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    • pp.1645-1646
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    • 2001
  • The objective of this study was to develop an in vitro digestion technique to estimate bioavailable energy values of different corn hybrids in swine and poultry. A total of 21 samples were investigated; 18 normal corn (NC) and 3 high-oil corn (HOC) hybrids. One step-two enzymes digestion system was introduced to develop the in vitro technique. The gross energy (GE) values of NC hybrids were correlated with the in vitro disappearing energy values (IVE; r=0.85, p<0.01), the in vitro energy digestibilities (IVED; r=0.70, p<0.01), and the in vitro DM digestibilities (IVDM; r=0.55, p<0.05). It appears, however, that IVE values of NC and HOC hybrids were not significantly different according to the one step-two enzyme digestion system. Results of in vivo and in vitro estimates suggested that there was no significant correlation between them in poultry. The IVE value was regressed linearly with ME and DE values in swine with low regression coefficient (34 and 41%, respectively).