• Title/Summary/Keyword: Gamma Rays

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STUDY OF FLARE-ASSOCIATED X-RAY PLASMA EJECTIONS : II. MORPHOLOGICAL CLASSIFICATION

  • KIM YEON-HAN;MOON Y.-J.;CHO K.-S.;BONG SU-CHAN;PARK Y.-D.
    • Journal of The Korean Astronomical Society
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    • v.37 no.4
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    • pp.171-177
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    • 2004
  • X-ray plasma ejections often occurred around the impulsive phases of solar flares and have been well observed by the SXT aboard Yohkoh. Though the X-ray plasma ejections show various morphological shapes, there has been no attempt at classifying the morphological groups for a large sample of the X-ray plasma ejections. In this study, we have classified 137 X-ray plasma ejections according to their shape for the first time. Our classification criteria are as follows: (1) a loop type shows ejecting plasma with the shape of loops, (2) a spray type has a continuous stream of plasma without showing any typical shape, (3) a jet type shows collimated motions of plasma, (4) a confined ejection shows limited motions of plasma near a flaring site. As a result, we classified the flare-associated X-ray plasma ejections into five groups as follows: loop-type (60 events), spray-type (40 events), jet-type (11 events), confined ejection (18 events), and others (8 events). As an illustration, we presented time sequence images of several typical events to discuss their morphological characteristics, speed, CME association, and magnetic field configuration. We found that the jet-type events tend to have higher speeds and better association with CMEs than those of the loop-type events. It is also found that the CME association (11/11) of the jet-type events is much higher than that (5/18) of the confined ejections. These facts imply that the physical characteristics of the X-ray plasma ejections are closely associated with magnetic field configurations near the reconnection regions.

CRYSTALLIZAT10N OF $\gamma$-GLUTAMYLCYSTEINE SYNTHETASE FROM Escherichia coli (대장균주로부터 분리한 GSH-1 효소의 결정화)

  • 황광언;김경규
    • Korean Journal of Crystallography
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    • v.4 no.2
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    • pp.100-104
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    • 1993
  • Reduced glutathione (GSH) plays a vital role in the metabolism of all cells. Glutathions, a tripeptide cowfosed of glutamic acid, cysteane, and gtycina is synthesized by two synthesized reutions. The first is catalyzed by Y-glutamylcysteine synthetase (GSH-I) and the second by glutathione synthetase (GSH-ll). The glutathione biosynthetic pathway of E. coziis mainly controlled by nonallosteric feedback inhibition of GHS-I by GSH. Determination of the three-dimensional structure of GSH-I by X-ray crystallography is necessary in order to understand the structure-function relationship at the molecular level. As the (irst step toward its structure determination, crystallization of 5. coli V-glutamylcystfine synthetase (GSH-I) has been achived using the hanging drop vapor diffusion method and capillaw method. Crystals of GSH-I have been grown from ammonium sulfate solution. The crystals grew at room temperature within 10 days to dimensions of 0.2 m x 0.2 m x 0.2 ml by hanging drop vapor diffusion method and diffracted to about 4 A resolution using synchrotron X-rays. Another crystal, grown by the capillary method to dimensions of 0.25 mm x 0.25 mm x 0.3 mm within 40 days, diffracted to about 4 A resolution using X-rays from a rotating anode.

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Genotoxicological Safety of the ${\gamma}$-ray Irradiated Astragali Radix, Glycyrrhizae Radix and Aurantii nobilis Pericarpium in the Ames Test (Ames test를 이용한 감마선 조사 황기, 감초 및 진피의 유전독성학적 안전성 평가)

  • 함연호;육홍선;조성기
    • Food Science and Preservation
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    • v.8 no.1
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    • pp.54-59
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    • 2001
  • The three medicinal herbs, Astragali Radix, Glycyrrhizae Radix and Aurantii nobilis Pericarpium, irradiated with γ-rays have been tested for their possible genotoxicity. The hot water extracts of the 10 kGy γ-ray irradiated herbs were examined in the Salmonella mutagenicity test(histidine reversion assay; Ames test) using Salmonella. typhimurium TA98 and TA100 as tester strains. No mutagenicity was detected in this assay both with and without metabolic activation. The safety of the herbs irradiated with γ-rays at tactical doses needs to be evaluated in further tests of genotoxicity in vivo and chronic and reproductive toxicity.

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Development of Dual-Window Phantom for Output Measurement of Medical Linacs (의료용 선형가속기 출력측정용 듀얼윈도우 팬텀 개발)

  • Jeong, Dong Hyeok;Kwak, Dong Won;Moon, Young Min;Kang, Yeong-Rok;Kim, Jeung Kee;Lee, Man Woo
    • Progress in Medical Physics
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    • v.23 no.4
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    • pp.229-233
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    • 2012
  • A small water phantom (dual-window phantom) was developed to improve the output measurement efficiency of medical linacs. This phantom is suitable for determining the quality index and output dose for high-energy photon beams. The phantom has two opposite windows and two independently rotating axes. The two axes measure the tissue phantom ratio (TPR) and the percentage depth dose (PDD) simply without requiring chamber movement by rotating the phantom around its axis. High-energy photon beams from a Co-60 irradiator and a medical linac were used to evaluate the phantom. The measured quality index is in good agreement with the reference values; the measured and reference values are within 0.2% of each other for the Co-60 gamma rays and within 1.4% for 6 and 10 MV X-rays. This phantom is more practical for routine output measurements, resulting in the prevention of potential human errors.

Analysis on Fluorine-18 Shielding Efficiency of Double Shield Apron using Acrylic (아크릴을 활용한 이중 차페 Apron의 F-18 차폐 효율 분석)

  • Lee, Gwon-Seong;Jeon, Yeo-Ryeong;Kim, Yong-Min
    • Journal of the Korean Society of Radiology
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    • v.15 no.7
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    • pp.957-964
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    • 2021
  • Fluorine-18 used in PET/CT scans is a radioactive isotope that emits positrons, and high energy annihilation gamma rays and beta rays cause exposure to radiation workers. In this study, as part of a plan to reduce the exposure dose of radiation workers working in the Department of Nuclear Medicine, the cause of the low shielding efficiency of Apron for F-18 was identified, and the effectiveness of the Apron double-shielded with acrylic was evaluated. L-Block, Apron+acrylic, Apron, Acrylic+Apron, and Acrylic five shields are used to measure the dose, and the tendencies were compared by performing a Monte Carlo simulation. As a result, it was found that the shielding rate of Apron double shielded with acrylic was about 4 to 8% higher than that of Apron single shielded. To the extent that it does not significantly affect the user's activity, double-shielded personal protective clothing with an appropriate acrylic thickness could help reduce radiation workers' exposure.

Feasibility study of CdZnTe and CdZnTeSe based high energy X-ray detector using linear accelerator

  • Beomjun Park;Juyoung Ko;Jangwon Byun;Byungdo Park ;Man-Jong Lee ;Jeongho Kim
    • Nuclear Engineering and Technology
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    • v.55 no.8
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    • pp.2797-2801
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    • 2023
  • CdZnTeSe (CZTS) has attracted attention for applications in X- and gamma-ray detectors owing to its improved properties compared to those of CdZnTe (CZT). In this study, we grew and processed single crystals of CZT and CZTS using the Bridgeman method to confirm the feasibility of using a dosimeter for high-energy X-rays in radiotherapy. We evaluated their linearity and precision using the coefficient of determination (R2) and relative standard deviation (RSD). CZTS showed sufficient RSD values lower than 1.5% of the standard for X-ray dosimetry, whereas CZT's RSD values increased dramatically under some conditions. CZTS exhibited an R2 value of 0.9968 at 500 V/cm, whereas CZT has an R2 value of 0.9373 under the same conditions. The X-ray response of CZTS maintains its pulse shape at various dose rates, and its properties are improved by adding selenium to the CdTe matrix to lower the defect density and sub-grain boundaries. Thus, we validated that CZTS shows a better response than CZT to high-energy X-rays used for radiotherapy. Further, the applicability of an onboard imager, a high-energy X-ray (>6 MV) image, is presented. The proposed methodology and results can guide future advances in X-ray dose detection.

Gamma-ray Irradiation on Radio Sensitivity in Cnidium officinale Makino (천궁 돌연변이 유발을 위한 최적 감마선 조사량)

  • Jeong, Jin Tae;Ha, Bo Keun;Han, Jong Won;Lee, Jeong Hoon;Lee, Sang Hoon;Oh, Myeong Won;Park, Chun Geon;Ma, Kyung Ho;Chang, Jae Ki;Kim, Sang Hoon;Kim, Jin Baek;Kang, Si Yong;Ryu, Jai Hyunk
    • Korean Journal of Medicinal Crop Science
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    • v.28 no.5
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    • pp.339-346
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    • 2020
  • Background: Cnidium officinale Makino have been used in traditional medicine in Northeast Asia. Although gamma-ray mutagenesis has been used to develop breeding resources with novel characteristics, research on the radiation sensitivity of C. officinale Makino is limited. Hence, the optimal gamma-ray dosage for mutation breeding in C. officinale Makino was investigated. Methods and Results: Seedstocks were exposed to doses of gamma rays (5 Gy - 50 Gy), and subsequently planted in a greenhouse. After 30 days of sowing, the survival rates and growth decreased rapidly at doses above 20 Gy, while all individuals died at 50 Gy. The median lethal dose (LD50) was 25.65 Gy, and the median reduction doses (RD50) for plant height, number of stems, and fresh weight were 12.81, 9.32, and 23.26 Gy, respectively. Post-irradiation levels of malondialdehyde (MDA), peroxidase (POD), and chlorophyll in the aerial parts of the plant were quantified using spectrophotometry. Relative to the controls, the levels of MDA and POD increased, while the level of chlorophyll decreased at doses ≥ 10 Gy, indicating cellular damage. Conclusions: A dose of 20 Gy was found to be optimal for mutation breeding in C. officinale Makino.

A Study on the Performance Evaluation of Standard Gamma Irradiation System Using Monte Carlo Code (몬테카를로 코드를 활용한 표준 감마선 조사장치의 성능평가에 관한 연구)

  • Park, Won-Seok;Heo, Seung-Uk;Kim, Jang-Oh;Min, Byung-In
    • Journal of the Korean Society of Radiology
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    • v.12 no.2
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    • pp.179-184
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    • 2018
  • In this study, we compared the measured values of the effective beam size of standard gamma irradiator with the simulation results to provide a useful means to the effective beam area determination. Results of the simulation and measured using ion chamber was distributed in a relative error of 4.5 ~ 7.3% of the case of air kerma rate. The size of the effective beam area is when the simulation was implemented in the horizontal direction 27cm, 21.6cm vertical direction, the measured result using a film was obtained similar results with the horizontal direction 26.5cm, 21.9cm vertical direction. The relative error in the horizontal direction is 1.85% and 1.38% vertical effective beam area was also similarly distributed around the field gamma rays. As a result of the study, it was confirmed that the effectiveness of the simulation was sufficient for the gamma irradiation system. In particular, it is small relative errors in the effective beam size than the air kerma rate is considered to be due to the size of the beam is determined by geometric factors rather than the capacity of the standard source. A further study is needed to improve the reliability of the photon energy distribution diagram using simulation.

Evaluation of DNA Double Strand Breaks in Human and Mouse Lymphocyte Following ${\gamma}-Irradiation$ (${\gamma}-Ray$ 조사에 따른 사람의 정상임파구와 마우스 정상임파구의 DNA Double Strand Break 발생율에 대한 비교분석)

  • Kim Tae Hwan;Kim Sung Ho;Chung In Yong;Cho Chul Koo;Ko Kyung Hwan;Yoo Seong Yul
    • Radiation Oncology Journal
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    • v.11 no.2
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    • pp.219-225
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    • 1993
  • The evaluation of radiation-induced DNA double strand breaks (DSB) was made following irradiation of human lymphocytes, murine lymphocytes and EL-4 leukemia cells over a wide dose range of $^{60}Co\;{gamma}-rays.$ In lipopolysaccharide (LPS) or phytohemagglutinin (PHA)-stimulated murine lymphocytes, the slopes of the stand scission factor (SSF) revealed that lymphocytes with LPS increased DNA DSB formation by a factor of 1.432 (p<0.005). Furthermore, strand break production was relatively inefficient in the T lymphocytes compared to the B lymuhocytes. And EL-4 leukemia cells were found to form significantly more DNA DSB to a greater extent than normal lymphocytes (p<0.005). The in vitro studies of the intrinsic radiosensitivity between human lymphocytes and murine lymphocytes showed similar phasic kinetics. However, murine lymphocytes were lower in DNA DSB formation and higher in the relative radiation dose of 10 percent DNA strand breaks at 3.5 hours following ${gamma}-irradiation$ than human lymphocytes. Though it is difficult to interpret these results, these differences may be result from environmental and genetic factors. From our data, if complementary explanations for this difference will be proposed, the differences in the dose-effect relationship for the induction of DSB between humans and mice must be related to interspecies variations in the physiological condition of the peripheral blood in vitro and not to differences in the intrinsic radiation sensitivity of the lymphocytes. These results can be estimated on the basis of dose-effect correlation enabling the interpretation of clinical response and the radiobiological parameters of cytometrical assessment.

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Coexpression of PCNA and p21 for DNA repair in small intestinal crypt cells of mouse with 60Co γ-rays irradiation (방사선을 조사한 마우스의 소장 음와세포에서 DNA 수복을 위한 PCNA와 p21의 발현 양상)

  • Hong, Suji;Hwang, Insun;Ahn, Meejung;Shin, Taekyun;Joo, Hong-gu;Park, HyunJeong;Jee, Youngheun
    • Korean Journal of Veterinary Research
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    • v.45 no.4
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    • pp.457-464
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    • 2005
  • The irradiation of radioactive ${\gamma}-ray$ induces apoptosis of radiosensitive organs for homeostasis. In this study, we investigated the repair mechanisms for homeostasis in the small intestine after cell damage by $^{60}Co\;{\gamma}-ray$ irradiation. The apoptosis was most frequently observed in the crypt cells of the small intestine after four and six hours by radioactive ${\gamma}-ray$ irradiation, and the frequency of apoptosis was proportional to the amount of irradiation. Also, the number of apoptotic cells was coincident with expression pattern of p53. Interestingly, PCNA (proliferating cell nuclear antigen) which is engaged in DNA replication and repair was expressed in apoptotic cells of small intestinal crypts. Also, it was observed that cell-cycle regulator p21 which is known to induce cell-cycle arrest is co-expressed in the same apoptotic cells of irradiated small intestinal crypt cells. These findings suggest that the co-expression of PCNA and p21 proteins, which may lead to resistance to DNA damage through cell-cycle arrest is closely associated with repair of damaged gastrointestinal cells after ${\gamma}-ray$ irradiation.