• 한방재활의학과학회지
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• 제31권2호
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• pp.41-48
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• 2021

Objectives To determine the evidence of effectiveness and safety of extracorporeal shock wave therapy (ESWT) with meridian and acupoint theory for knee osteoarthritis. Methods By March 3, 2021, five foreign electronic databases and six Korean medical electronic databases were reviewed with the key words 'extracorporeal shock wave' and '(acupoint OR acupuncture point)'. This key words was set up to increase the sensitivity of the search. After the search, knee osteoarthritis study was selected based on the title and abstract and then included after full-texts were read. Results Five randomized controlled trials were eligible in our inclusion criteria. The meta-analysis of three studies showed positive results for the using ESWT with meridian and acupoint theory for knee osteoarthritis compared with the control group on efficancy rate, visual analog scale and lysholm knee score. but there remains a conundrum regarding the safety of ESWT in the treatment of knee osteoarthritis. Conclusions Most of studies showed ESWT with meridian and acupoint theory were statistically effective to knee osteoarthritis. However there are limitations that the number of selected studies was small, risk of bias was unclear. So use of ESWT with meridian and acupoint theory for knee arthritis has limited evidence compared to usual care.

• Journal of Ginseng Research
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• 제43권4호
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• pp.684-691
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• 2019

Background: We have reported that defective nef and gag genes are induced in HIV-1-infected patients treated with Korean Red Ginseng (KRG). Methods: To investigate whether KRG treatment and highly active antiretroviral therapy (HAART) affect genetic defects in the pol gene, we amplified and sequenced a partial pol gene (p-pol) containing the integrase portion (1.2 kb) by nested PCR with sequential peripheral blood mononuclear cells over 20 years and compared it with those patients at baseline, in control patients, those taking ginseng-based combination therapy (GCT; KRG plus combinational antiretroviral therapy) and HAART alone. We also compared our findings to look for the full-length pol gene (pol) (3.0-kb) Results: Twenty-patients infected with subtype B were treated with KRG for $116{\pm}58months$ in the absence of HAART. Internal deletion in the pol gene (${\Delta}pol$) was significantly higher in the KRG group (11.9%) than in the control group and at baseline; its detection was significantly inhibited during GCT as much as during HAART. In addition, the ${\Delta}pol$ in p-pol significantly depended on the duration of KRG treatment. In pol, the proportion of ${\Delta}pol$ was significantly higher in the KRG group (38.7%) than in the control group, and it was significantly inhibited during GCT and HAART. In contrast, the proportion of stop codon appeared not to be affected by KRG treatment. The PCR success rate was significantly decreased with longer GCT. Conclusion: The proportion of ${\Delta}pol$ depends on template size as well as KRG treatment. HAART decreases the detection of ${\Delta}pol$.

• 대한건축학회논문집:구조계
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• 제35권5호
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• pp.191-202
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• 2019

This study examines the effect of luminance contrast ratio of character on readability and visual fatigue during an hour-long reading session while using a tablet PC in ambient environments having low luminance limited to $25cd/m^2$. Experiments were conducted with four patterns of the tablet's luminance contrast ratio of characters, namely 1:2.5, 1:4.5, 1:6.5, and 1:8.5, in low ambient luminance of $9cd/m^2$ and $25cd/m^2$. The obtained results show that the characters can be easily read at the luminance contrast ratio of character of 1:8.5 under surface luminance of $25cd/m^2$. Visual fatigue was evaluated through a subjective survey of symptoms. Physical, psychological, and visual fatigue were observed at a surface luminance of $9cd/m^2$, whereas solely visual fatigue was felt at a surface luminance of $25cd/m^2$. By assessing the physical fatigue using the value, it has been found that smaller the luminance contrast ratio of character, greater is the CFF variation rate. Furthermore, readability is poor and visual fatigue can be observed when the surface luminance is lower than the ambient luminance. However, readability can be improved by increasing the luminance contrast ratio of character to a value of 1:8.5. Thus, in low luminance environments, luminance contrast ratio of characters can affect readability and fatigue. Consider providing the full form of "CFF" so that the acronym can be used unambiguously throughout the manuscript.

• 비만대사연구학술지
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• 제1권2호
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• pp.78-82
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• 2022

Liraglutide (Saxenda^R) is prescribed to induce and sustain weight loss in obese patients. The starting dose of liraglutide is 0.6 mg/day for 1 week, which is increased by 0.6 mg/day every week until the full maintenance dose of 3 mg/day is achieved. Such dose titration is needed to prevent side effects, which primarily include gastrointestinal problems such as nausea, diarrhea, constipation, vomiting, dyspepsia, and abdominal pain. A 35-year-old, reportedly healthy obese man receiving liraglutide treatment for obesity visited the emergency room complaining of generalized weakness and dizziness accompanied by repeated diarrhea and vomiting. He reported over 20 episodes of diarrhea starting the day after liraglutide dose escalation from 1.2 mg/day to 1.8 mg/day. Laboratory findings suggested pre-renal acute kidney injury, including serum creatinine 4.77 mg/dl, blood urea nitrogen (BUN) 37 mg/dl, estimated glomerular filtration rate (eGFR) 15 ml/min/1.73 m², and Fractional excretion of sodium 0.08. After volume repletion therapy, his renal function recovered to a normal range with laboratory values of creatinine 1.08 mg/dl, BUN 14 mg/dl, and eGFR 88 ml/min/1.73 m². This case emphasizes the need for caution when prescribing glucagon-like peptide-1 receptor agonists, including liraglutide, given the risk of serious renal impairments induced by volume depletion and dehydration through severe-grade diarrhea and vomiting.

• 상하수도학회지
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• 제35권1호
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• pp.93-100
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• 2021

Forward osmosis (FO) process is a chemical potential driven process, where highly concentrated draw solution (DS) is used to take water through semi-permeable membrane from feed solution (FS) with lower concentration. Recently, commercial FO membrane modules have been developed so that full-scale FO process can be applied to seawater desalination or water reuse. In order to design a real-scale FO plant, the performance prediction of FO membrane modules installed in the plant is essential. Especially, the flux prediction is the most important task because the amount of diluted draw solution and concentrate solution flowing out of FO modules can be expected from the flux. Through a previous study, a theoretical based FO module model to predict flux was developed. However it needs an intensive numerical calculation work and a fitting process to reflect a complex module geometry. The idea of this work is to introduce deep learning to predict flux of FO membrane modules using 116 experimental data set, which include six input variables (flow rate, pressure, and ion concentration of DS and FS) and one output variable (flux). The procedure of optimizing a deep learning model to minimize prediction error and overfitting problem was developed and tested. The optimized deep learning model (error of 3.87%) was found to predict flux better than the theoretical based FO module model (error of 10.13%) in the data set which were not used in machine learning.

• 한국물환경학회지
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• 제27권4호
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• pp.461-466
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• 2011

The feasibility of utilizing food waste leachate as an external carbon source was tested to enhance biological nutrient removal from an industrial wastewater with an average flow rate of $164,800m^3/d$ and a low carbon/nitrogen ratio of 2.8. A considerable improvement in the removal of nitrogen and phosphorus was observed when a certain amount of the leachate, ranging from 70 to $142m^3/d$, was supplemented to the biological industrial wastewater treatment process. The addition of the leachate led to an increase in the BOD/N ratio (4.5) and the removal efficiency of nutritents from 29.7% to 71.7% for nitrogen and from 34.8% to 65.6% for phosphorus. However, an excessive dose of the leachate that significantly exceeded $120m^3/d$ caused serious operational problems, like oil-layer formation in the grit chamber and scum layer in the primary clarifier. Thus, an supplement of food waste leachate at a dose acceptable to an existing facilities can be a practical and effective means to enhance the nutrient removal from industrial wastewater and to dispose of the food waste leachate.

• 한국수처리학회지
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• 제26권6호
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• pp.73-80
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• 2018

In this study, the solids removal characteristics using T-P sludge generated from PACl coagulation were analyzed by laboratory scale and full scale experiment. As the amounts of T-P sludge injection into the raw sewage influent increased at the rate of 0, 1, 2, 3, 4 %, the suspended solids concentrations after 20 minutes setting test decreased to 210, 137, 91, 64, 43 mg/L, respectively. The filtration time required for dewatering test of the raw sewage influent decreased to 982, 728, 658, 581, 492 sec for 0, 1, 2, 3, 4% of T-P sludge injection, respectively. As the amounts of PACl coagulant into the effluent from final setting tank increased at 0, 10, 20, 30, 40 mg/L, the required filtration times for T-P sludge increased into 12.3, 41.7, 53.7, 67.2, 79.5 sec and the dewaterability of T-P sludge decreased. After T-P sludge returned into the primary settling tank on J-si sewage treatment plants, the effluent concentrations of COD, SS, T-N and T-P from primary settling tank into bioreactor decreased by 35.9, 27.9, 22.2, and 52.6% due to the coagulation effects of the T-P sludge. Finally, it was found that the return of T-P sludge into the primary settling tank could result into the sludge reduction having a lower water content of 3.03% p than in case of the only T-P sludge dehydration.

• 한국인터넷방송통신학회논문지
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• 제20권6호
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• pp.41-50
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• 2020

본 논문에서는 기존의 점자 학습 제품의 단점들을 보완한 점자 교육 시스템을 다룬다. 시각장애인 전용 어플리케이션은 사용자 편의성을 위해 터치 제스처 및 음성 안내를 통하여 전체 기능을 수행할 수 있도록 구성한다. 점자키트는 아두이노와 3D 프린팅을 통해 교육 목적에 맞게 제작한다. 시스템은 다음과 같은 기능들을 지원한다. 첫 째, 초성·종성·모음·약어 등 기초적인 점자의 학습. 둘 째, 단계별 퀴즈를 풀어 학습한 점자를 확인하는 기능. 셋 째, 모르는 점자가 있을 때 번역하는 기능이다. 실험을 통한 터치 제스처의 인식률과 점자 표현의 정확도를 확인하였고 번역의 경우 의도한대로 번역이 되는 것을 확인하였다. 이 시스템을 통해 시각장애인이 효율적으로 점자를 학습할 수 있다.

• 한국환경보건학회지
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• 제47권1호
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• pp.78-86
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• 2021

Objectives: The purposes of this study were to investigate the installation rates and status of indoor smoking rooms in public facilities and to determine the level of compliance level with smoke-free policies in accordance with the National Health Promotion Act. Methods: A visiting survey was conducted on 1,206 public facilities in the Seoul Metropolitan Area and the Daegu and Gyeongsangbuk-do Province area. Researchers selected public facilities such as bars, coffee houses, and internet cafes using convenient sampling. They visited without prior notice, checked the existence of indoor smoking rooms, and recorded their status. Results: Internet cafes (110/116) had the highest installation rate of indoor smoking rooms, followed by bowling clubs (17/19) and billiard rooms (87/100). Depending on the type of business, 50-88% of smoking rooms were not completely enclosed. Coin karaoke rooms showed the least inadequacy in this regard. In addition, out of 512 smoking rooms, in 33% (n = 169) smoking indoors was observed in non-smoking areas. Only 9% of public facilities were in full compliance with the indoor smoke-free regulation. Conclusions: It was found that most of the public facilities with indoor smoking rooms did not comply with the smoke-free policy, and smoking was still observed inside some facilities. Therefore, there is a need for a policy that prohibits indoor smoking rooms completely.

• 아태비즈니스연구
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• 제11권1호
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• pp.145-165
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• 2020

Purpose - The purpose of this study is to suggest strategies and solutions for entering China in the tariff and non-tariff sectors of the cosmetic industry. Design/methodology/approach - This study analyzed the import tariff rate of cosmetics in China, and analyzed the export cost by actually interviewing the exporting companies to derive the economic effect of non-tariff measures. Findings - First, We proposed the use of the FTA business model (basic cosmetics), the use of Korea-China FTA tariffs (foam cleansing, toothpaste), and the use of APTA tariffs (perfume). Second, We proposed cooperation between the governments to facilitate customs clearance procedures and improvement of FTA awareness among corporate practitioners. Third, We proposed the expansion and support of the AEO MRA system and the expansion of Korea-China MOU conclusions regarding the certification system, and the international standardization of domestic licensing system and technical conditions. Fourth, We proposed the use of government-supported projects related to obtaining overseas certifications and overseas expansion through collaboration with the same industry. Research implications or Originality - HS3304 products excluded from the Korea-China FTA should take full advantage of the FTA business model. In addition, the non-tariff measure costs are fixed costs per year, so the ratio decreases as the number of exports and export volume increases.