• 한국펄프종이공학회:학술대회논문집
• /
• 한국펄프종이공학회 2007년도 춘계학술대회논문집
• /
• pp.157-165
• /
• 2007

Restoration behavior of folded Korea bank note was studied. The variables were folding radii (0.5, 1, 3, 5. 7, 9 mm) and folding time. Initially, bank note was completely folded to make $180^{\circ}$ against predetermined radius panel, and restored angles were measured according to allowed restoration time. We found as folding radius was smaller and as folding time was longer, restoration speed of folding angle became slower and the amount of final restoration was smaller, respectively. Initial restoration angles were related to the elastic moduli of the bank notes, and final restoration angles were inversely related to the TEA of the bank notes, respectively.

• Biotechnology and Bioprocess Engineering:BBE
• /
• 제6권4호
• /
• pp.237-243
• /
• 2001

Substantial progress has been made towards understanding the folding mechanisms of proteins in virto and in vivo even though the general rules governing such folding events remain unknown. This paper reviews current folding models along with experimental approaches used to elucidate the folding pathways. Protein misfolding is discussed in relation to disease states, such as amyloidosis, and the recent findings on the mechanism of converting normally soluble proteins into amyloid fibrils through the formation of intermediates provide an insight into understanding the pathogenesis of amyloid formation and possible cules for the development of therapeutic treatments. Finally, some commonly adopted refolding strategies developed over the part decade are summarized.

• 한국가구학회지
• /
• 제13권1호
• /
• pp.42-47
• /
• 2002

The folding chairs are one of the most necessary furniture for satisfying the moderns' wants which is utilized for limited space rationally. These folding chairs are variously used in interior spaces such as offices, dining areas, and resting areas. They are very easy to move around, so that quiet useful in out door areas, too. Moreover, they play an important role in public spaces as supplementary furniture. The folding chairs have one or several axes, and they are classified according to type of axes like below. 1. Method of divide seating board into 2 and fold, 2. Method of folds seating board and lay on bottom of backboard, 3. Method of fold back board and lay on top of seating board, 4. Method of fold into contact with left and right, 5. Method of gathering legs into one and fold. The folding chairs have to be easy to operate, firm and safe, light for moving around easily, designed for able to change units whenever they have damaged. Change of residential spaces according to the trend towards the nuclear family maximized necessity of limited spaces' use. Therefore, this study provides insights for development of new methods' of folding chairs.

• 대한전기학회:학술대회논문집
• /
• 대한전기학회 1988년도 전기.전자공학 학술대회 논문집
• /
• pp.591-594
• /
• 1988

A three-step heuristic algorithm for PLA column folding and row folding of column-folded PLA is presented, which is significantly faster than the earlier works and provides nearly optimal results. The three steps are i) min-cut partition of vertices in the column (or row) intersection graph, ii) determination of products' order using Fiduccia's min-net cut algorithm, and iii) head-tail pairing for column folding, while some heuristics are proposed for deciding row folding pairs. The time complexity of this algorithm is O($n^{2}$log n) compared to the O($n^{3}$) - O($n^{4}$) of the earlier works.$^[2][3][9]$ For a test PLA with 23 inputs, 19 outputs and 52 products, the number of column folding pairs obtained using this algorithm is 20 which is optimal, as compared to 17 in a previous work.

• 대한전기학회:학술대회논문집
• /
• 대한전기학회 1988년도 전기.전자공학 학술대회 논문집
• /
• pp.595-598
• /
• 1988

In this paper, a new folding algorithm for design of high density PLA's is proposed. This algorithm generates transform matrix so that programmed region of each row becomes narrow. Based on transform matrix, folding pair is selected. In the process of generating transform matrix, interval degree and dense degree are used to improve folding ratio. This paper also proposes an efficient folding pair graph which has short time of selection folding pair. This proposed algorithm is named PLAFOLII and implemented in C language on VAX-11/750 (UNIX) computer. Through various example, efficiency of this algorithm is verified.

• Bulletin of the Korean Chemical Society
• /
• 제29권4호
• /
• pp.741-748
• /
• 2008

We have studied the folding mechanism of $\beta$ -hairpins in the proteins 1GB1, 3AIT and 1A2P by conducting unfolding simulations at moderately high temperatures. The analysis of trajectories obtained from molecular dynamics simulations in explicit aqueous solution suggests that the positions of the hydrophobic core residues lead to subtle differences in the details of folding dynamics. However, the folding of three different hairpins can be explained by a unified mechanism that is a blend of the hydrogen-bond-centric and the hydrophobiccentric models. The initial stage of $\beta$-hairpin folding involves various partially folded intermediate structures which are stabilized by both the van der Waals interactions of hydrophobic core residues and the electrostatic interactions of non-native hydrogen bonds. The native structure is obtained by forming native contacts in the final tune-up process. Depending on the relative positions of the hydrophobic residues, the actual mechanism of hairpi n folding may or may not exhibit well-defined intermediates.

• BMB Reports
• /
• 제38권3호
• /
• pp.275-280
• /
• 2005

For most of proteins to be active, they need well-defined three-dimensional structures alone or in complex. Folding is a process through which newly synthesized proteins get to the native state. Protein folding inside cells is assisted by various chaperones and folding factors, and misfolded proteins are eliminated by the ubiquitin-proteasome degradation system to ensure high fidelity of protein expression. Under certain circumstances, misfolded proteins escape the degradation process, yielding to deposit of protein aggregates such as loop-sheet polymer and amyloid fibril. Diseases characterized by insoluble deposits of proteins have been recognized for long time and are grouped as conformational diseases. Study of protein folding mechanism is required for better understanding of the molecular pathway of such conformational diseases.

• 한국전기전자재료학회논문지
• /
• 제21권5호
• /
• pp.421-425
• /
• 2008

In this research, a 8-bit CMOS 2 stage folding A/D converter is designed, For low power consumption and small chip size, the A/D converter is designed by using folding and interpolation circuit. Folding circuit is composed of the transistor differential pairs which are connected in parallel. It reduces the number of comparator drastically. The analog block composed of folding block, current interpolation circuit, and three stage current comparator is designed with differential-mode for high speed operation. The simulation in a $0.35\;{\mu}m$ CMOS process. shows DNL and SNDR of 0.5LSB and 47 dB at 250 MHz/s sampling frequency.

• BMB Reports
• /
• 제57권5호
• /
• pp.216-231
• /
• 2024

Mammalian genomes are intricately compacted to form sophisticated 3-dimensional structures within the tiny nucleus, so called 3D genome folding. Despite their shapes reminiscent of an entangled yarn, the rapid development of molecular and next-generation sequencing technologies (NGS) has revealed that mammalian genomes are highly organized in a hierarchical order that delicately affects transcription activities. An increasing amount of evidence suggests that 3D genome folding is implicated in diseases, giving us a clue on how to identify novel therapeutic approaches. In this review, we will study what 3D genome folding means in epigenetics, what types of 3D genome structures there are, how they are formed, and how the technologies have developed to explore them. We will also discuss the pathological implications of 3D genome folding. Finally, we will discuss how to leverage 3D genome folding and engineering for future studies.

• 한국의상디자인학회지
• /
• 제20권4호
• /
• pp.1-16
• /
• 2018

This study focuses on the correlation between Kotgal and paper-folding. This paper first examines the meaning and history of Korean ancient Kotgal and then investigates relationship between Kotgal and Korean paper-folding culture which has been inherited in various ways. Throughout the study, literature research and analysis have been conducted along with empirical studies. The results of the study are as follows. First, it has been told that Kotgal was used a as a trident hat symbolizing the sky, land, and man, whereas Korean paper-folding is known as closely related to the folk beliefs which had existed since ancient times. From ancient times, the Korean ancestors expressed the Three Gods representing beauties of the nature, 'sky(Chun), land(Ji) and man(In)' on the conical hat and prayed for their wish to the heaven. Second, Kotgal has been evolved in various ways from ancient times through Goryeo and Joseon Dynasty to present. The form of Kotgal has begun with folding and this is closely related to the origin of Korean paper-folding, which is the Korean traditional craft. Third, the paper-folding tradition of Korea has been variously applied in the Korean culture such as rituals, life crafts and plays and expresses the unconventional philosophical concepts unique of Korea. In conclusion, this study evidently shows that the Korean philosophical ideas behind Kotgal which originated from ancient paper-folding are scientific and systematic.