• Journal of Microbiology and Biotechnology
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• v.25 no.11
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• pp.1827-1834
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• 2015

The SMG1 lipase from Malassezia globosa is a newly found mono- and diacylglycerol (DAG) lipase that has a unique lid in the loop conformation that differs from the common alpha-helix lid. In the present study, we characterized the contribution of three residues, L103 and F104 in the lid and F278 in the rim of the binding site groove, on the function of SMG1 lipase. Site-directed mutagenesis was conducted at these sites, and each of the mutants was expressed in the yeast Pichia pastoris, purified, and characterized for their activity toward DAG and p-nitrophenol (pNP) ester. Compared with wild-type SMG1, F278A retained approximately 78% of its activity toward DAG, but only 11% activity toward pNP octanoate (pNP-C8). L103G increased its activity on pNP-C8 by approximately 2-fold, whereas F104G showed an approximate 40% decrease in pNP-C8 activity, and they both showed decreased activity on the DAG emulsion. The deletion of 103-104 retained approximately 30% of its activity toward the DAG emulsion, with an almost complete loss of pNP-C8 activity. The deletion of 103-104 showed a weaker penetration ability to a soybean phosphocholine monolayer than wild-type SMG1. Based on the modulation of the specificity and activity observed, a pNP-C8 binding model for the ester (pNP-C8, N102, and F278 form a flexible bridge) and a specific lipid-anchoring mechanism for DAG (L103 and F104 serve as "anchors" to the lipid interface) were proposed.

• Journal of KIISE:Computer Systems and Theory
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• v.36 no.2
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• pp.60-67
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• 2009

Analyzing protein-protein interactions(PPI) is an important task in bioinformatics as it can help in new drugs' discovery process. However, due to vast amount of PPI data and their complexity, efficient visualization of the data is still remained as a challenging problem. We have developed efficient and effective visualization system that integrates Gene Ontology(GO) and PPI network to provide better insights to scientists. To provide efficient data visualization, we have employed dynamic interactive graph drawing methods and context-based browsing strategy. In addition, quick and flexible cross-reference system between GO and PPI; LCA(Least Common Ancestor) finding for GO; and etc are supported as special features. In terms of interface, our visualization system provides two separate graphical windows side-by-side for GO graphs and PPI network, and also provides cross-reference functions between them.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.35 no.2B
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• pp.279-286
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• 2010

RFID reader protocol is an interface between RFID readers and higher (host) such as RFID middlewares and applications. At present, reader protocols provided by vendors are different from each other and there are compatibility problems in environment using heterogeneous readers. In this paper, to solve this problem, an RFID reader which supports LLRP(Low Level Reader Protocol), a well-known standard reader protocol presented by EPCglobal is designed and implemented. It is designed with two modules and supports various interfaces for easy adaptation to various applications. The LLRP protocol is implemented over a embedded LINUX multi-thread environment. It not only supports almost all properties of LLRP, and is designed with flexible hardware/software architecture to meet various requirements.

• The KIPS Transactions:PartA
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• v.16A no.3
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• pp.199-208
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• 2009

Recently, there are many embedded system prototyping tools for helping embedded system designers to trial their product before it releases to the market. A prototype is very important for early embedded system design to grasp the desire functions, to get a good performance, to create delightful user interface, and to increase the valuable of the product. Prototyping tools can be classified by three categories: Physical, Virtual and Modeling prototyping. The integration of these prototyping tools becomes valuable for speed up time-to-market and for decrease design cost when design embedded system. The problem comes up because these tools sometime do not provide an instrument for communicating each other. In this paper, we propose a flexible and reusable mechanism for integrate these tools base on JavaBeans and ActiveX technology. We show how this mechanism can be employed in various prototyping tools.

• 제어로봇시스템학회:학술대회논문집
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• 2005.06a
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• pp.957-962
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• 2005

Today, the elderly is increasing gradually in the Republic of Korea society and this problem will be more serious in the near future. Therefore, engineering support for aged people is required. We are establishing a new field of healthcare engineering for elderly people and aiming to support for aged people and disabled people using adaptive control and instrument technology. In this paper, the goal is to implement the shared control of a robot mobility aid for the elderly. As using this type of assistive technology to be useful by its intended user community, it supports elderly people and handicapped people to live independently in their private homes. The interface transforms the force applied by the user into the robot's motion. Devices like buttons, joysticks, and levers already exist for relaying user input; however, they require hand displacement that would loosen or otherwise release the user's hold. Such interfaces make operation very difficult and potentially unsafe. Therefore, we propose a shared control system. It's safe more than joysticks and buttons. The shared control is a means of registering the user's intention through physical interaction. It's an important component in the development of robotic elderly assistant. The concept of shared control describes a system which is two or more independent control systems. We are using that the three component blocks consist of pressure sensor (flexible force sensor), circuit of measurement and transfer function. Experimental trials of this paper have been tested at the indoor environment. The robot is able to know the user intended direction through haptic device were logged along with the robot's force sensor.

• Journal of Communications and Networks
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• v.2 no.1
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• pp.5-17
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• 2000

cdma2000 offers several enhancement as compared to TIA/EIA-95, although it remains fully compatible with TIA/EIA-95 systems and allows for a smooth migration from one to the other-Major new capability include:1)connectivity to GSM-MAP in addition to IP and IS-41 networks; 2) new layering with new LAC and MAC architectures for improved service multiplexing and QoS management and efficient use of radio resource ;3) new bands and band widths of operation in support of various operator need and constraints, as well as desire for a smooth and progressive migration to cdma 2000; and 4) flexible channel structure in support of multiple services with various QoS and variable transmission rates at up to 1 Mbps per channel and 2 Mbps per user. Given the phenomenal success of wireless services and desire for higher rate wireless services. improved spectrum efficiency was a major design goal in the elaboration of cdma2000. Major capacity enhancing features include; 1) turbo coding for data transmission: 2)fast forward link power control :3) forward link transmit diversity; 4) support of directive antenna transmission techniques; 5) coherent reverse link structure; and 6) enhanced access channel operation. As users increasingly rely on their cell phone at work and at home for voice and data exchange, the stand-by time and operation-time are essential parameters that can influence customer's satisfaction and service utilization. Another major goal of cdma2000 was therefore to enable manufacturers to further optimize power utilization in the terminal. Major battery life enhancing features include; 1) improved reverse link performance (i.e., reduced transmit power per information bit; 2) new common channel structure and operation ;3) quick paging channel operation; 4) reverse link gated transmission ; and 5) new MAC stated for efficient and ubiquitous idle time idle time operation. this article provides additional details on those enhancements. The intent is not to duplicate the detailed cdma2000 radio access network specification, but rather to provide some background on the new features of cdma2000 and on the qualitative improvements as compared to the TIA/EIA-95 based systems. The article is focused on the physical layer structure and associated procedures. It therefore does not cover the MAC, LAC, radio resource management [1], or any other signaling protocols in any detail. We assume some familiarity with the basic CDMA concepts used in TIA/EIA-95.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2004.05a
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• pp.86-89
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• 2004

Organic thin film transistors (OTFTs) are fabricated on the plastic substrate through 4-level mask process without photolithographic patterning to yield the simple fabrication process. And we herewith report for the effect of dielectric surface modification on the electrical characteristics of OTFTs. The KIST-JM-1 as an organic molecule for the surface modification is deposited onto the surface of zirconium oxide $(ZrO_2)$ gate dielectric layer. In this work, we have examined the dependence of electrical performance on the interface surface state of gate dielectric/pentacene, which may be modified by chemical properties in the gate dielectric surface.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.48 no.7
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• pp.57-64
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• 2011

To adjust the difference of bandwidth between host interface and NAND flash memory, DRAM is adopted as the buffer management in SSD (Solid-state Disk). In this paper, we propose cost-effective techniques to enhance SSD performance instead of using expensive high bandwidth DRAM. The SSD data can be classified into three groups such as user data, meta data for handling user data, and FEC(Forward Error Correction) parity/ CRC(Cyclic Redundancy Check) for error control. In order to improve the performance by considering the features of each data, we devise a flexible burst control method through monitoring system and a page based FEC parity/CRC application. Experimental results show that proposed methods enhance the SSD performance up to 25.9% with a negligible 0.07% increase in chip size.

• Journal of the Microelectronics and Packaging Society
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• v.13 no.2 s.39
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• pp.27-31
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• 2006

We reported the grain growth of pentacone on $HfO_2$ film depending on OTS treatment. The hydrophilic $HfO_2$ thin film was changed into hydrophobic with less interface energy by OTS treatment. The grain size of pentacene on OTS/$HfO_2$ film was increased from 50 nm to 90 nm with the variation of surface energy and the structure was maintained 3-dimensional island structure. Pentacene on OTS/$HfO_2$ surface was directionally arrayed due to appearance of the only thin film phase without bulk phase by OTS treatment.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.42 no.2 s.302
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• pp.87-100
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• 2005

In this paper, we propose a new selective temporal error concealment algerian best suited for H.264/AVC. The proposed algorithm performs selective temporal error concealment depending on whether the lost block is at background or foreground. It the corrupted macroblock is decided as at background, then the simple temporal replacement is performed. Also we propose replacing a lost block at foreground with the selective average of respectively estimated blocks from the multiple reference frames. This paper supposes error-corrupted H.264/AVC video bitstreams over CDMA2000 (or UMTS) air interface. It is shown that under Flexible Macroblock Ordering (FMO) coding of H.264/AVC, the proposed algorithm provides PSNR gain up to 1.18dB compared to built-in algorithm in the K264/AVC test model. In addition, the proposed error concealment method has average PSNR improvement of 0.33dB compared with that under N-slice coding mode. The proposed algorithm also provides better subjective video quality than other conventional error concealment algorithms.