• Title/Summary/Keyword: Feedback Structure

Search Result 954, Processing Time 0.026 seconds

Serine 389 phosphorylation of 3-phosphoinositide-dependent kinase 1 by UNC-51-like kinase 1 affects its ability to regulate Akt and p70 S6kinase

  • Kim, Kidae;Park, Sung Goo;Park, Byoung Chul;Kim, Jeong-Hoon;Kim, Sunhong
    • BMB Reports
    • /
    • v.53 no.7
    • /
    • pp.373-378
    • /
    • 2020
  • Phosphorylation of the signaling component by protein kinase often leads to a kinase cascade or feedback loop. 3-Phosphoinositide-dependent kinase 1 (PDK1) signaling pathway diverges into various kinases including Akt and p70 S6 kinase (p70S6k). However, the PDK1 feedback mechanism remains elusive. Here, we demonstrated that UNC-51-like kinase (ULK1), an autophagy initiator kinase downstream of mechanistic target of rapamycin (mTOR), directly phosphorylated PDK1 on serine 389 at the linker region. Furthermore, our data showed that this phosphorylation affected the kinase activity of PDK1 toward downstream substrates. These results suggest a possible negative feedback loop between PDK1 and ULK1.

Implementation of Auto-tuning Positive Position Feedback Controller Using DSP Chip and Microcontroller (디지털신호처리 칩과 마이크로 컨트롤러를 이용한 자동 조정 양변위 되먹임 제어기의 구현)

  • Kwak, Moon K.;Kim, Ki-Young;Bang, Se-Yoon
    • Transactions of the Korean Society for Noise and Vibration Engineering
    • /
    • v.15 no.8 s.101
    • /
    • pp.954-961
    • /
    • 2005
  • This paper is concerned with the implementation of auto-tuning positive position feedback controller using a digital signal processor and microcontroller. The main advantage of the positive position feedback controller is that it can control a natural mode of interest by tuning the filter frequency of the positive position feedback controller to the natural frequency of the target mode. However, the positive position feedback controller loses its advantage when mistuned. In this paper, the fast fourier transform algorithm is implemented on the microcontroller whereas the positive position feedback controller is implemented on the digital signal processor. After calculating the frequency which affects the vibrations of structure most, the result is transferred to the digital signal processor. The digital signal processor updates the information on the frequency to be controlled so that it can cope with both internal and external changes. The proposed scheme was installed and tested using a beam equipped with piezoceramic sensor and actuator. The experimental results show that the auto-tuning positive position feedback controller proposed in this paper can suppress vibrations even when the target structure undergoes structural change thus validating the approach.

Implementation of Adaptive Positive Popsition Feedback Controller Using DSP chip and Microcontroller (디지털신호처리 칩과 마이크로 컨트롤러를 이용한 적응 양변위 되먹임 제어기의 구현)

  • Kwak, Moon-K.;Kim, Ki-Young;Bang, Se-Yoon
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
    • /
    • 2005.05a
    • /
    • pp.498-503
    • /
    • 2005
  • This paper is concerned with the implementation of adaptive positive position feedback controller using a digital signal processor and microcontroller The main advantage of the positive position feedback controller is that it can control a natural mode of interest by tuning the filter frequency of the positive position feedback controller to the natural frequency of the target mode. However, the positive position feedback controller loses its advantage when mistuned. In this paper, the fast fourier transform algorithm is implemented on the microcontroller whereas the positive position feedback controller is implemented on the digital signal processor. After calculating the frequency which affects the vibrations of structure most the result is transferred to the digital signal processor. The digital signal processor updates the information on the frequency to be controlled so that it can cope with both internal and external changes. The proposed scheme was installed and tested using a beam equipped with piezoceramic sensor and actuator. The experimental results show that the adaptive positive position feedback controller proposed in this paper can suppress vibrations even when the target structure undergoes structural change thus validating the approach.

  • PDF

Feedback Model Updating: Application to Indeterminate Structure (궤환 모델 개선법 : 부정정 구조물에의 적용)

  • 정훈상;박영진;박윤식
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
    • /
    • 2003.05a
    • /
    • pp.59-64
    • /
    • 2003
  • The parameter modification of the initial FEM model to match it with the experimental results needs the modal information and the modal sensitivity matrix to the parameter change. There are two cases this methodology is ill-equip to deal with; the deficiency of the necessary modal information and the ill-conditioning of the sensitivity matrix. In this research, a novel concept of the feedback exciter that uses the summation of the white noise and the signals from the measurement sensors multiplied with feedback gains as the reference signal is proposed. There are 2 advantages using this external feedback excitation. First, we can use the change of the system response such as modal data by the active energy Path from the sensor to the exciter. This change of the system response can be additional clues to the system dynamics that we want to know. Secondly, the external energy Path alternates the offset of the Parameter change to the system response. That means the modal sensitivity of the parameters becomes different from the original sensitivities by the feedback excitation. Through the feedback loop, we can change the similar modal sensitivities of some updating parameters and consequently discriminate the parameters using the closed-loop modal data. To demonstrate the discrimination performance, the parameter estimation of an indeterminate structure by use of the feedback method is introduced.

  • PDF

Equalization of 8-VSB Signals using Complex-Valued Decision Feedback Filter (복소수 판정궤환 필터를 이용한 8-VSB 신호의 채널등화)

  • Chung, Won-Zoo
    • The Transactions of the Korean Institute of Electrical Engineers D
    • /
    • v.55 no.7
    • /
    • pp.332-334
    • /
    • 2006
  • In this paper, we present an equalization scheme for 8-VSB signals for the ATSC DTV system. We propose a complex feedback filter and complex feedback sample generator for DFE to equalize 8-VSB signals in order to efficiently remove multipath distortions causing leakages from the qudrature component. We show that the proposed structure outperforms the conventional DFE used for the digital VSB which uses a real-valued feedback filter with real-valued decisions.

Output feedback semiglobal stabilization for a nonlinear system (광범위한 안정 영역을 갖는 출력만을 이용한 제어기 설계)

  • 오성록
    • Journal of the Korean Institute of Telematics and Electronics S
    • /
    • v.34S no.9
    • /
    • pp.60-66
    • /
    • 1997
  • WE consider the stabilization of a class of multivariable nonlinear system using variable structure output feedback control. A high-gain observer is used to estimate state variable while rejecting the effect of the disturbances. We design a globally bounded output feedback variable structure controller that semi-globally stabilize the closed-loop system, while state variables do not exhibit a peaking.

  • PDF

Dynamic range expansion of active pixel sensor with output voltage feedback (출력 전압 피드백을 통한 능동 화소 센서의 동작 범위 확장)

  • Seo, Min-Woong;Seo, Sang-Ho;Kong, Jae-Sung;Shin, Jang-Kyoo
    • Journal of Sensor Science and Technology
    • /
    • v.18 no.4
    • /
    • pp.274-279
    • /
    • 2009
  • In this paper, a wide dynamic range active pixel sensor(APS) with output voltage feedback structure has been designed by a 2-poly 4-metal 0.35 $\mu$m standard CMOS technology. We presented a novel APS with output voltage feedback, which exhibits a wide dynamic range. The dynamic range increases at the cost of an additional diode and an additional MOSFET. The output voltage feedback structure enables the control of the output voltage level by itself, as incident light power varies. It is confirmed that the light level which the output voltage level of proposed APS is saturated is about 120,000 lux, which is higher than that of a conventional 3-transistor APS.

A New Robust Discrete Integral Static Output Feedback Variable Structure Controller with Disturbance Observer and Integral Dynamic-Type Sliding Surface for Uncertain Discrete Systems (불확실 이산 시스템을 위한 외란관측기와 적분 동특성형 슬라이딩 면을 갖는 새로운 둔감한 이산 적분 정적 출력 궤환 가변구조제어기)

  • Lee, Jung-Hoon
    • The Transactions of The Korean Institute of Electrical Engineers
    • /
    • v.59 no.7
    • /
    • pp.1289-1294
    • /
    • 2010
  • In this paper, a new discrete integral static output feedback variable structure controller based on the a new integral dynamic-type sliding surface and output feedback discrete version of the disturbance observer is suggested for the control of uncertain linear systems. The reaching phase is completely removed by introducing a new proposed integral dynamic-type sliding surface. The output feedback discrete version of disturbance observer is presented for effective compensation of uncertainties and disturbance. A corresponding control with disturbance compensation is selected to guarantee the quasi sliding mode on the predetermined integral dynamic-type sliding surface for guaranteeing the designed output in the integral dynamic-type sliding surface from any initial condition for all the parameter variations and disturbances. Using discrete Lyapunov function, the closed loop stability and the existence condition of the quasi sliding mode is proved. Finally, an illustrative example is presented to show the effectiveness of the algorithm.

LDO Regulator with Feedback Network Improved Transient Response (과도응답을 향상시킨 피드백 구조를 갖는 LDO 레귤레이터)

  • Park, Kyeong-Hyeon;Kwon, Min-Ju;Koo, Yong-Seo;Yoo, Seok-Won
    • Journal of IKEEE
    • /
    • v.20 no.3
    • /
    • pp.307-309
    • /
    • 2016
  • In this paper, we propose LDO regulator with improved transient using a simple feedback structure in conventional LDO regulator. This proposed circuit has the feedback structure which reduces the response time of overshoot appeared in the output of conventional LDO regulator. Therefore, this LDO regulator can be a more stable operation. Thus, the proposed feedback structure is to operate such as conventional LDO regulator without changing the area, it complements the disadvantage of LDO regulator with noise in the output. This circuit was designed to using a Dongbu Hitek 0.18um CMOS process.

LDO Regulator with Improved Regulation Characteristics and Feedback Voltage Buffer Structure (Feedback Buffer 구조 및 향상된 Regulation 특성을 갖는 LDO regulator)

  • Jung, Jun-Mo;Park, Tae-Ryong
    • Journal of IKEEE
    • /
    • v.26 no.3
    • /
    • pp.462-467
    • /
    • 2022
  • The feedback buffer structure is proposed to alleviate the overshoot and undershoot phenomenon and the regulation of the output voltage. The conventional LDO regulator undergoes a regulation voltage change caused by a constant load current change. An LDO regulator with a feedback voltage sensing structure operates in the input voltage range of 3.3 to 4.5 V and has a load current of up to 150 mA at output voltage of 3 V. According to the simulation results, a regulation value of 6.2 mV was ensured when the load current uniformly changed to 150 mA.