• The Journal of Korean Obstetrics and Gynecology
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• v.32 no.3
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• pp.192-213
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• 2019

Objectives: The purpose of this study is to analyze the domestic study trends of pharmacopuncture therapy on obstetrics and gynecological diseases in Korean literature, through reviewing the clinical and experimental studies. Methods: We searched for clinical and experimental studies using pharmacopuncture therapy on obstetrics and gynecological diseases, published from January 2000 to May 2019, through 5 Korean databases. The study design, target disease, type of pharmacopuncture, method of intervention, and study results were analyzed. Results: 36 experimental studies and 15 clinical studies were finally included according to inclusion and exclusion criteria. In experimental studies, there were 12 studies about postmenopausal osteoporosis, 9 studies about obesity, 4 studies about endometriosis, 3 studies about hemostatic effects and analgesic anticoagulative effects, 2 studies about ovarian function, and analgesic antiphlogistic anticoagulative effects, and 1 study about menopausal symptoms. In clinical studies, there were 3 studies about obesity, postpartum disorders, dysmenorrhea, and women's urologic disease, and 1 study about menopausal symptoms, atypical squamous cells of undetermined significance (ASCUS) and breast cancer. Various types of pharmacopuncture have been proved to have a therapeutic effect in each of those obstetrics and gynecological diseases. Conclusions: This study indicates that pharmacopuncture therapy could be a good treatment for obstetrics and gynecological diseases. However, more well-designed and high-quality clinical researches are needed in further studies, to prove the effectiveness and safety of pharmacopuncture therapy.

• Asian Oncology Nursing
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• v.3 no.2
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• pp.112-121
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• 2003

The purpose of these study was to analyze the contents and trend of researches done on oncology nursing in the past five years in Korea and to suggest its direction for the future research. Methods: 214 nursing studies published from 1998 to 2003 were selected for the analysis. They were examined for the source, design of study, type of subjects, the intervention outcomes of experimental research, the key words and theme of the oncology research. Results: 1. 139(64.9%) of 214 studies were masters thesis and doctoral dissertations. There were 196(91.6%) quantitative researches and 18 qualitative researches. Quantitative research consisted of 28(14.3%) experimental and 168(85.7%) non- experimental studies. Among non-experimental studies, there were 53 correlations, 78 descriptives, 14 comparatives and 23 methodological studies. 2.The main subjects of the study were cancer patients in general(43.7%) and breast cancer patients (18.3%). According to the treatment types, patients receiving chemotherapy were the highest number distribution as 23 of all researches. 3. Social support, fatigue, stress, hope, and quality of life were the most frequently used concepts in correlational studies.4. Education, providing information, oral care, exercise, relaxation and foot massage were the most frequent nursing interventions. Most frequently measured outcomes variable were self-care, pain control, nausea & vomiting, oral discomfort and anxiety. 5. Key words used most frequently were quality of life, educational need, pain controls and fatigue. 6. The themes of qualitative researches were illness experience, family experience and adaptation process. More than 50% of qualitative researches used phenomenologic method. Conclusion: Researches on cancer nursing in Korea have been increased. Descriptive design is being dominant and few experimental studies are being done For the future, it is necessary to conduct international studies to compare, replicate and to establish the effective nursing interventions.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.30 no.1
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• pp.74-86
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• 2017

Objectives : This study aimed to assess the scientific evidence for the use of Hwanglyeonhaedok-tang, a traditional herbal formula, in the treatment of rhinitis, and prepare the basis for the investigational new drug application by analyzing the experimental studies. Methods : Ten electronic databases were searched up to December, 2016 without language limitation. Experimental studies on the anti-inflammatory and anti-allergic effects of Hwanglyeonhaedok-tang against rhinitis were included. We extracted data about study design, characteristics of intervention, outcomes, and pharmacological effects from the included studies and summarized them. Results : Eight hundred and thirty-three potentially relevant studies were identified, of which 18 experimental studies met our inclusion criteria. Of 18 included studies, 5 had conducted cell viability test, and all studies had reported that Hwanglyeonhaedok-tang was non-cytotoxic. Hwanglyeonhaedok-tang exhibits anti-inflammatory effect by regulating the inflammation-related cytokines including nitric oxide(NO), prostaglandin $E_2(PGE_2)$, interleukin-6(IL-6), and tumor necrosis $factor-{\alpha}(TNF-{\alpha})$ in vitro and in vivo. Hwanglyeonhaedok-tang exhibits anti-allergic effect by suppressing eosinophil, and histamine levels. Hwanglyeonhaedok-tang helps in the recovery of nasal mucous membrane by supressing goblet cells, heat shock protein 70, and substance P. Conclusions : This study suggests that Hwanglyeonhaedok-tang has the potential to be developed as therapeutic agent for rhinitis. Further experimental and clinical studies needed to be performed to prove the safety and efficacy.

• The Journal of Internal Korean Medicine
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• v.38 no.1
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• pp.10-19
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• 2017

Objective: This study reviewed experimental studies on the effects of Korean medical treatment for diabetes mellitus (DM). Method: We reviewed 24 studies about DM that had been published since 2013. We searched the Korean Institute of Oriental Medicine (KIOM) database with the keyword '당뇨', '消渴', 'Diabetes'. Results: 1. The studies used various Korean medicine treatments; 15 used single medicinal herbs, 6 used herbal complexes, and 2 used acupuncture. 2. The measurement parameters used in the studies included blood glucose, body weight, histochemical change, lipid parameters, and food/water intake. Anti-diabetic effects were demonstrated in most of the studies. 3. The experimental animals used were rats or mice. There were 15 type 1 diabetes models, 7 type 2 diabetes models, and one normal model. Among them, 13 cases of chemical diabetes induced by Streptozotosin (STZ, type 1 diabetes inducer) were the most common. Conclusion: Further articles on Korean medical treatment of DM should be studied.

• Journal of Sasang Constitutional Medicine
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• v.30 no.3
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• pp.1-24
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• 2018

Objective This study was aimed to provide the information about Cheongsimyeonja-tang by domestic papers and theses. Method 50 Domestic papers related to Cheongsimyeonja-tang were selected according to the criteria. These papers were classified and analyzed by research designs, methods and results. Result The following results were obtained in this study. 1. 19 experimental studies on the effect of Cheongsimyeonja-tang were mainly focused on anti-aging, followed by anti-allergy, anti-inflammation, improvement of immune system. And there were 4 experimental studies on the safety of Cheongsimyeonja-tang, proving safety by acute toxicity test, nephrotoxicity test, drug interaction, and test of residual ingredients after decoction. 2. 25 clinical studies on the effect of Cheongsimyeonja-tang were mainly focused on cardiovascular and cerebral vascular diseases, followed by psychiatric and otologic disorder, dermatologic and musculoskeletal diseases. Also, there were 2 studies on the effect of Cheongsimyeonja-tang for diabetes insipidus, macular degeneration, digestive disorder in terminal cancer, drug-induced hepatitis. 3. More evidenced studies on Cheongsimyeonja-tang are needed and it is recommended that psychiatric questionnaire should be used for assessing the effects of Cheongsimyeonja-tang.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.34 no.4
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• pp.204-214
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• 2023

Digital therapy using extended reality (XR) holds great promise for addressing the mental health needs of adolescents and young adults. This study addresses a notable research gap in South Korea by systematically reviewing XR-based digital therapy for the mental health of South Korean adolescents and young adults. We analyzed 26 studies encompassing various aspects, including study type, publication date, research field, research methodology, data sources, program types, program content, sample characteristics, target population, assessment tools, and program effectiveness. Notably, 46.15% of the studies employed an experimental design, whereas over 53% utilized non-experimental approaches. Experimental studies lacked a genuine design, standardized questionnaires, and control variables. Similarly, non-experimental studies failed to report specific literature selection criteria. Consequently, future studies should adopt rigorous methodologies to enhance reliability and validity. Moreover, over 85% of the 26 studies focused solely on virtual reality and did not incorporate augmented or mixed reality. This study identifies the limitations of the previous research. These findings emphasize the need for structured investigations to advance the development of XR-based digital therapy to promote mental health in adolescents and young adults in South Korea.

• Korean Journal of Oriental Medicine
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• v.13 no.2 s.20
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• pp.83-90
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• 2007

The aim of the study was to analyze recent trends of experimental studies regarding to acupuncture and moxibustion (AM) through reviewing the 492 papers in the PubMed database in order to help researchers from overlapping study on the same theme and to spur them to investigate experimental studies on AM with understanding the current flow of that. For the analysis, we include papers in which abstract was written in English. First, we performed quantitative analysis of the experimental studies using whole of the first filtrated 492 papers. From this analysis, we could obtain the followings: 'Trends of study in the most frequently appeared journals and leading authors in experimental study of AM'. 'The number of papers and name of journals by leading authors in experimental study of AM'. 'Trends of Korean papers in the most frequently appeared journals and Korean leading authors in experimental study of AM", 'Classification of experimental studies related to acupuncture and moxibustion according to intervention methods or individual country' and 'Assortment of experimental studies related to acupuncture and moxibustion in terms of intervention methods on leading countries'. Second, we collected 72 papers considering impact factor of the journal and influential effect of the papers' result for qualitative analysis, and we divided the papers into pain related one or not, because the effect of AM on pain is major subject of AM study. The results showed that experimental studies regarding to AM still has several weakness such as limited usage of acupuncture points and inclined application of electroacupucture even though there are 361 acupuncture points in the human body and various kinds of stimulation methods using traditional needles and moxibustion. Therefore, we suggest that researchers should pay more attention to the study on basic AM research creatively and systematically through strengthening and enhancing the cooperation among colleges, research institutes and hospitals. Moreover, in order to promote the basic research of the AM, it is required that we need cross-disciplinary research as well as international collaboration research.

• Research in Community and Public Health Nursing
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• v.12 no.3
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• pp.639-646
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• 2001

The purpose of this study is to analyze the trend of nursing research related to family support and to provide an effective direction for future research by conducting a review of the Korean nursing literature from 1980 to 2000. A total of 73 studies were analyzed with the following results. 1) The number of studies related to family support has been rapidly increasing since 1984, and 77% of those were conducted in the 1990s. 48 studies, 65% of those analyzed. were degree-based research including 4 doctoral theses (4%) and 45 master's theses (62%). 2) Based on the objective frame of study types developed by Lee et al. (991), the types of studies were analyzed: 56 studies, 76.6% of those reviewed, belonged to factor-relating: 9 studies (12.4%) belonged to factor-isolating: 7 studies (9.6%) belonged to situation-producing: and only 1 study (1.4%) belonged to situation-relating research, respectively. 3) In terms of research design, most studies of analyzed (90.4%) were conducted by non-experimental design, and 7 studies (9.6%) were conducted by experimental design. But, qualitative research related to family support was not found. 4) In terms of research subjects, target populations of experimental studies were patients with arthritis, mental disorder, tuberculosis, coronary artery disease and hypertension. In correlational studies, 51 studies, 69.9% of those analyzed, were conducted to patients with renal failure, cancer and hemiplegia, and 5 studies (6.8%) were conducted to aged people and adolescents. 5) Study concepts used in correlational studies were quality of life, anxiety and depression, self-esteem, hope, role behavior, compliance and self-care activities. The quality of life was most often used among studies with 12.5% of those analyzed. 6) Nursing interventions, including diet therapy, family involving education and supportive care, used in experimental studies mostly showed positive effects on client involvement and home health improvement. However, the nursing interventions of mental health rehabilitation and resistance exercise showed neutral and negative results. The findings of this study provide evidence that more empirical research including experimental or qualitative studies should be conducted actively to improve nursing practice related to family support. Also, to promote more diverse nursing interventions, a family assessment tool especially for Korean families needs to be developed.

• Journal of Korean Academy of Nursing
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• v.44 no.5
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• pp.484-494
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• 2014

Purpose: The purpose of this study was to identify trends for studies published in the Journal of Korean Academy of Nursing and journals published by member societies from inaugural issues to 2010. Methods: A total of 6890 studies were analyzed using descriptive statistics. Results: Quantitative studies accounted for 83.6% while qualitative studies accounted for 14.4%. Most frequently used research designs were quasi-experimental (91.1%) for experimental research and survey (85.2%) for non-experimental research. Most frequent study participants were healthy people (35.8%), most frequent nursing interventions, nursing skills (53.5%), and 39.8% used knowledge, attitude and behavior outcomes for dependent variables. Most frequently used keyword was elderly. Survey studies decreased from 1991 to 2010 by approximately 50%, while qualitative studies increased by about 20%. True experimental research (1.2%) showed no significant changes. Studies focusing on healthy populations increased from 2001-2005 (37.5%) to 2006-2010 (41.0%). From 1970 to 2010, studies using questionnaire accounted for over 50% whereas physiological measurement, approximately 5% only. Experimental studies using nursing skill interventions increased from 1970-1980 (30.4%) to 2006-2010 (64.0%). No significant changes were noted in studies using knowledge, attitude and behavior (39.9%) as dependent variables. Conclusion: The results suggest that further expansion of true experimental, qualitative studies and physiological measurements are needed.

• The Journal of Korean Medicine
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• v.36 no.4
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• pp.80-103
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• 2015

Background: This study investigated current research trends in bee venom acupuncture in Korea. Materials and methods: The literature in Korea was reviewed using the search engines Science and Technology Society Village, Korean Studies Information Service System, National Discovery for Science Leaders, and Oriental Medicine Advanced Searching Integrated System. The keywords searched were "bee venom," "apitoxin," "apitherapy," and "bee sting." We selected 412 studies, which included Korean literary studies, experimental studies, and clinical studies. Results: We classified them by publication year, research type, disease and topic, and quality assessment. Among bee venom-related studies, clinical studies (235 studies) outnumbered experimental studies (149 studies) and literary studies (28 studies). Nineteen experimental studies concentrated on the theme of "anticancer." In the type analysis of clinical studies, lumbar disorders comprised 45 of 235 studies, followed by the effect on body. Forty-two randomized controlled trials (RCTs) have been published from 2003 to date (2015). Twenty-two studies used appropriate randomization methods. Fourteen studies had a Jadad score of 4-5 points; 15 studies, 1-3 points; and 13 studies, 0 points. Conclusions: Bee venom treatment is based on Korean traditional medicine theory. Numerous research studies suggest its effectiveness. Effort and academic approach on bee venom are expected to receive a positive evaluation.