• Journal of Photoscience
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• 제10권1호
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• pp.149-155
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• 2003

The absorption, fluorescence and fluorescence-excitation spectra of concentrated toluene solutions of selected para substituted trans-stilbene derivatives provide strong evidence for aggregation. A red-shifted fluorescence spectrum peaking at 420 nm gains in intensity as the stilbene concentration is increased. The excitation spectrum of this new emission is well to the red of the normal stilbene absorption spectrum, consistent with the appearance of a red shifted shoulder in the UV spectrum. Formation of a fluorescent ground state dimer (or higher aggregate) is proposed to account for these observations. The presence of polar substituents is crucial to the formation of this ground state complex.

• 대한본초학회지
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• 제25권3호
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• pp.91-95
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• 2010

Objectives : Acori Rhizoma is one of the common widely used herbal medicines with diverse bioactive effects. However, little evidence has been reported about the potential anti-platelet activity of Acori Rhizoma. The present study examined the effects on platelet aggregation by Acori Rhizoma. Methods : In this study, we tested the in vitro effect of 16 kinds of Acori Rhizoma extracts by hot water or 70% ethanol on collagen-induced platelet aggregation in human whole blood using the impedance method of aggregometry. Results : Among them, 2 kinds of 70% ethanol extract and 1 kind of hot water extract showed the significant inhibiting effect on whole blood aggregation. In particular, Acorus gramineus extracts were selected as the most effective candidate. Conclusiions : The results from this experiment provide pharmacological evidence for the traditional medicine, suggesting that Acorus gramineus could be help problems of blood circulation more than Acorus tatarinowii.

• International journal of advanced smart convergence
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• 제6권1호
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• pp.1-8
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• 2017

Diverse types of malicious code such as evasive Server-side Polymorphic are developed and distributed in third party open markets. The suspicious new type of polymorphic malware has the ability to actively change and morph its internal data dynamically. As a result, it is very hard to detect this type of suspicious transaction as an evidence of Server-side polymorphic mobile malware because its C&C server was shut downed or an IP address of remote controlling C&C server was changed irregularly. Therefore, we implemented Simulated C&C Server to aggregate activated events perfectly from various Server-side polymorphic mobile malware. Using proposed Simulated C&C Server, we can proof completely and classify veiled server-side polymorphic malicious code more clearly.

• 한국농업기계학회:학술대회논문집
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• 한국농업기계학회 1993년도 Proceedings of International Conference for Agricultural Machinery and Process Engineering
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• pp.1254-1263
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• 1993

Representing knowledge uncertainty , aggregating evidence confidences , and propagation uncertainties are three key elements that effect the ability of a rule-based expert system to represent domains with uncertainty . Fuzzy set theory provide a good mathematical tool for representing the vagueness associated with a variable when , as the condition of a rule , it only partially corresponds to the input data. However, the aggregation of ANDed and Ored confidences is not as simple as the intersection and union operators defined for fuzzy set membership. There is, in fact, a certain degree of compensation that occurs when an expert aggregates confidences associated with compound evidence . Further, expert often consider individual evidences to be varying importance , or weight , in their support for a conclusion. This paper presents a flexible approach for evaluating evidence and conclusion confidences. Evidences may be represented as fuzzy or nonfuzzy variables with as associat d degree of certainty . different weight can also be associated degree of certainty. Different weights can also be assigned to the individual condition in determining the confidence of compound evidence . Conclusion confidence is calculated using a modified approach combining the evidence confidence and a rule strength. The techniques developed offer a flexible framework for representing knowledge and propagating uncertainties. This framework has the potention to reflect human aggregation of uncertain information more accurately than simple minimum and maximum operator do.

• 동의생리병리학회지
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• 제27권2호
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• pp.239-245
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• 2013

In in vitro study, the anti-platelet aggregation effect of Shiitake mushroom extract was examined by measuring the collagen induced platelet aggregation and the DPPH radical scavenging. In in vitro study, anti-thrombotic effect of Shiitake mushroom extract was examined using the carotid artery thrombosis rat model. Carotid artery thrombosis rat model was made by 35% $FeCl_3$ treatment. After that, we investigate thrombus weight and blood flow. In platelet aggregation test, the extract significantly inhibited platelet aggregation in a concentration dependent manner(p<.001). Also, extract increased DPPH radical scavenging activity in a concentration dependent manner. Extract significantly inhibited thrombus weight to compare with control group. And blood passage time were shorter in the Shiitake mushroom extract supplemented groups than in control group. These results provide experimental evidence that Shiitake mushroom can be used to prevent platelet aggregation and thrombosis, then could apply the clinical diseases such as cardiovascular disease, and so on.

• BMB Reports
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• 제55권7호
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• pp.323-335
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• 2022

Together with neuronal loss, the existence of insoluble inclusions of alpha-synuclein (α-syn) in the brain is widely accepted as a hallmark of synucleinopathies including Parkinson's disease (PD), multiple system atrophy, and dementia with Lewy body. Because the α-syn aggregates are deeply involved in the pathogenesis, there have been many attempts to demonstrate the mechanism of the aggregation and its potential causative factors including post-translational modifications (PTMs). Although no concrete conclusions have been made based on the previous study results, growing evidence suggests that modifications such as phosphorylation and ubiquitination can alter α-syn characteristics to have certain effects on the aggregation process in PD; either facilitating or inhibiting fibrillization. In the present work, we reviewed studies showing the significant impacts of PTMs on α-syn aggregation. Furthermore, the PTMs modulating α-syn aggregation-induced cell death have been discussed.

• Bulletin of the Korean Chemical Society
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• 제19권6호
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• pp.650-654
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• 1998

Aggregations of 1,1'-diethyl-2,2'-carbocyanine iodide (DCI) and 1,1'-diethyl-2,2'-dicarbocyanine iodide (DDT) in aqueous solution have been investigated by the steady-state absorption spectroscopy. The equilibrium constants for dimerization of DCI and DDT are found to be $(9.8{\pm}0.5){\times}10^4 \;and\; (1.6{\pm}0.5){\times}10^5\; M^{-1}$, respectively, at 293 K. The enthalpy changes for the dimerization of DCI and DDT are -6.7±0.7 and -7.7±0.8 kcal/mol, respectively. The results show that the dispersion force plays an important role in the aggregation of DCI and DDT in aqueous solution. The absorption bandwidth of DCI/ethanol system has been measured as a function of temperature, providing the evidence for no strong interaction between DCI and solvent molecules. The participation of hydrophobic force in driving the aggregation is suggested. For the first time, DCI in aqueous solution is found to form a new aggregate which has both J- and H- bands.

• 한국정보통신학회논문지
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• 제17권9호
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• pp.2055-2062
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• 2013

범죄 증거의 새로운 형태인 디지털 증거는 기존의 증거와 기능 및 역할에 있어서 거의 차이점이 없으며, 증거로서의 법적 인정 및 역할이 점차 증가할 것으로 예상된다. 포렌식 수사관은 다수의 증거 보유 장치(예, 컴퓨터 시스템, 저장 매체 등)에 저장되어 있는 막대한 양의 데이터로부터, 사건과 관련된 실마리를 찾기 위하여 많은 시간을 소모해야 한다. 따라서 조사 시간을 단축하기 위해서는 잠재적인 관련 증거의 중요성에 근거하여 순서화 및 순위화가 필요하다. 본 연구에서는 포렌식 조사 시에, 정확한 증거를 선정하게 함으로서 증거 분석 우선순위를 결정하는 방법을 제안한다. 제안된 방식은 증거 조사 소요시간, 증거의 가치, 증거간의 연관성 그리고 사건과 시간과의 연관성과 같은 다수의 부정확한 요소가 퍼지 집합 함수를 사용한 의사 결정에 사용되는 다기준 의사 결정에 근거한다.

• 대한한의학회지
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• 제25권3호
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• pp.99-104
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• 2004

Objectives : To study the Live Blood Condition of chronic shoulder measurement. Methods : Twenty-one patients were studied. The observation items of the Live Blood Condition are the form's abnormality and cohesion of red blood cells, the abnormality of hemoglobin and the toxicity in plasma. Results : 1. The form's abnormality and cohesion of red blood cells observed were erythrocyte aggregation (8 persons), Rouleau (3 persons), target cells (7 persons), ovalocytes (3 persons), poikilocytes (2 persons). Double conditions observed were erythrocyte aggregation & target cells (3 persons), erythrocyte aggregation & poikilocytes (1 person), target cells & ovalocytes (l person). 2. The abnormality of hemoglobin and the toxicity in plasma observed were cholesterol crystals (5 persons), atherosclerotic plaque (3 persons), chylous (6 persons). 3. The form normality of red blood was generally observed in one woman. The normality of hemoglobin and the non-toxicity in plasma were generally observed in seven women. Conclusions : According to this study of the Live Blood Condition of women's shoulder measurement, these results suggest that the twenty-one patients evidence the conditions of extravasated blood and phlegm.

• Asian Pacific Journal of Cancer Prevention
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• 제15권22호
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• pp.9859-9863
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• 2014

Genetic epidemiological studies have shown that genetic susceptibility to esophageal cancer (EC) is an important cause of its high incidence within families in some areas of China. The purpose of this study was to obtain evidence of a genetic basis of EC in Xin-an and Xin-xiang counties in China. Familial aggregation and complex segregation analyses were performed of 79 EC families in these counties. The heritability of EC was examined using Falconer's method and complex segregation analysis was conducted with the SEGREG program in Statistical Analysis for Genetic Epidemiology (SAGE version 5.3.1). The results showed that the distribution of EC in families did not fit well into a binomial distribution. The heritability of EC among first-degree and second-degree relatives was $67.0{\pm}7.31%$ and $43.1%{\pm}9.80%$, respectively, and the summing up powered heritability was $53.2{\pm}6.74%$. The segregation ratio was 0.045. Complex segregation analysis showed that the genetic model of EC was additive. The current results provide evidence for an inherited propensity to EC in certain high-risk groups in China, and support efforts to identify the genes that confer susceptibility to this disease.