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http://dx.doi.org/10.6116/kjh.2010.25.3.091

Effects of Acori Rhizoma Extract on the in vitro Anti-platelet Activity in Human Whole Blood  

Choi, Go-Ya (Creative Research Team, Korea Institute of Oriental Medicine)
Kim, Seul-Ki (Center for Herbal Medicine Improvement Research, Korea Institute of Oriental Medicine)
Lee, In-Sun (Center for Herbal Medicine Improvement Research, Korea Institute of Oriental Medicine)
Baek, Ji-Seong (Department of Herbology, College of Oriental Medicine, Woosuk University)
Jeon, Won-Kyung (Center for Herbal Medicine Improvement Research, Korea Institute of Oriental Medicine)
Publication Information
The Korea Journal of Herbology / v.25, no.3, 2010 , pp. 91-95 More about this Journal
Abstract
Objectives : Acori Rhizoma is one of the common widely used herbal medicines with diverse bioactive effects. However, little evidence has been reported about the potential anti-platelet activity of Acori Rhizoma. The present study examined the effects on platelet aggregation by Acori Rhizoma. Methods : In this study, we tested the in vitro effect of 16 kinds of Acori Rhizoma extracts by hot water or 70% ethanol on collagen-induced platelet aggregation in human whole blood using the impedance method of aggregometry. Results : Among them, 2 kinds of 70% ethanol extract and 1 kind of hot water extract showed the significant inhibiting effect on whole blood aggregation. In particular, Acorus gramineus extracts were selected as the most effective candidate. Conclusiions : The results from this experiment provide pharmacological evidence for the traditional medicine, suggesting that Acorus gramineus could be help problems of blood circulation more than Acorus tatarinowii.
Keywords
Acori Rhizoma; platelet aggregation; Acorus gramineus; Acorus tatarinowii;
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Times Cited By KSCI : 5  (Citation Analysis)
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