Objectives : This study demonstrates the effects of Daejo-hwan on learning and memory impairment induced by L-NAME (75 mg/kg) treatment and on cerebral ischemic damage induced by middle cerebral artery (MCA) occlusion in rats. Methods : Daejo-hwan emulsion (73.3 mg/100 g/l ml) was administered to rats along a timed study schedule. The Moms water maze was used for learning and memory test of the rats. The MCA was occluded by using the intraluminal thread method. The brain slices were stained by 2 % triphenyl tetrazolium chloride (TTC) and 1 % cresyl violet solution. Infarct size, neuron cell number and size in penumbra was measured by using computer image analysis system. Results : 1. The escape latency of the Daejo-hwan treated group decreased significantly with respect to the control group. 2.The memory score of the Daejo-hwan treated group showed increase tendency, And the swimming distance was not different between the normal, the control, and the Daejo-hwan treated group. 3. The infarct size of the Daejo-hwan treated group decreased significantly with respect to the control group. 4. The total infarct volume of the Daejo-hwan treated group showed decrease tendency. And the brain edema index of the Daejo-hwan treated group decreased significantly with respect to the control group. 5. The neuron cell number and cell size in penumbra of the Daejo-hwan treated group increased significantly with respect to the control group. Conclusions : According to the above results, it is supposed that Daejo-hwan is clinically applicable to the vascular dementia.
Journal of Korean Society of Industrial and Systems Engineering
/
v.40
no.4
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pp.137-146
/
2017
For the competitive business environment under purchase dependence, this paper proposes a new approximate calculation of order fill rate which is a probability of satisfying a customer order immediately using the existing inventory. Purchase dependence is different to demand dependence. Purchase dependence treats the purchase behavior of customers, while demand dependence considers demand correlation between items, between regions, or over time. Purchase dependence can be observed in such areas as marketing, manufacturing systems, and distribution systems. Traditional computational methods have a difficulty of the curse of dimensionality for the large cases, when deriving the stationary joint distribution which is utilized to calculate the order fill rate. In order to escape the curse of dimensionality and protect the solution from diverging for the large cases, we develop a greedy iterative search algorithm based on the Gauss-Seidel method. We show that the greedy iterative search algorithm is a dependable algorithm to derive the stationary joint distribution of on-hand inventories in the retailer system by conducting a comparison analysis of a greedy iterative search algorithm with the simulation. In addition, we present some managerial insights such as : (1) The upper bound of order fill rate can be calculated by the one-item pure system, while the lower bound can be provided by the pure system that consists of all items; (2) As the degree of purchase dependence declines while other conditions remain same, it is observed that the difference between the lower and upper bounds reduces, the order fill rate increases, and the order fill rate gets closer to the upper bound.
Journal of the Korea Society of Computer and Information
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v.22
no.1
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pp.89-97
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2017
This study examined the structural relationship between life stress perceived by university students and their gambling behaviors through their self-control and family support. For this, it conducted the questionnaire on life stress, self-control, family support and gambling behavior with 387 university students attending universities in Gwangju city and analyzed the data collected. The results of the analysis were described below. As a result of analyzing the direct effects of life stress on gambling behavior, self-control and family support, it was found that the life stress had the positive effect on gambling behavior and it meant that when the university students couldn't cope with the life stress effectively and felt frustrated, they were likely to be involved in gambling behavior to escape from their helplessness. In addition, as a result of analyzing the direct effects of life stress on self-control and family support, it was found that life stress had negative effect on self-control and family support. The more experiences of life stress they had, the lower their self-control was. As their life stress was higher, they didn't make supportive relationship network with family members. As a result of mediating effects, it was shown that self-control and family support played the partially negative roles in the relationship between life stress and gambling behavior and it suggested that as the life stress was perceived less, self-control was performed better and as family support was higher, gambling behavior was effectively reduced. These results of the research suggested that life stress could be handled actively through self-control and family support and development and distribution of the program to cope with life stress could minimize the gambling behaviors. Also the limitations of this study and necessity of further studies were discussed.
Lee Woo-Dong;Shin Jeong-Ryol;Kim Gil-Dong;Han Suk-Youn;Park Kee-Jun;Hong Jai-Sung;Ahn Tai-Ki;Lee Ho-Yong;Kim Jong-Wook
Proceedings of the KSR Conference
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2003.10c
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pp.322-326
/
2003
Dae-gu subway accident raise whole points in connection with safety facilities and operating of national urban transit system like rolling stocks, facilities, management of human. Rolling stock is made every effort for improvement of performance, guarantee of comfortableness, insurance of economical efficiency. But Security like safety of fire is not thoroughgoing enough. Especially, interior material has used although it is not prove its degree of safety. it is a main cause of Dae-gu subway accident. Safety regulation of urban transit vehicle that legislate for security in March 2000 does not applied manufacturing vehicles before in 2000. It has be prescribed in the regulations that incombustibles must be used. But detailed test standard related with incombustibles is not prescribe. Thus that regulation be required reinforcement of detailed test standard. Main cause of Dae-Gu subway accident is a fire in vehicle. However, many defects are found in infrastructure and operating vehicle of urban transit, such as inexperienced disposal of driver and CCC in early stage of the fire accident, unskilled opening and closing doors, insufficient escape facilities and safety facilities of a station house and tunnel, and incomplete communication system between vehicle and CTC, extraordinary step. Thus the aims of this study are prevention of urban transit accident, improvement plan of safety driving, and proposal of quick action plan through analysis of total faculty of vehicle.
Recently, Korea has been making efforts at the government level to overcome the national crisis that Japan's dependency on technology in the semiconductor and display materials sectors has also escaped due to export regulations on three materials carried out by Japan. Therefore, based on the data of the National Science & Technology Information Service (NTIS) operated by the government, we analyze the trend of R & D investment in the display field, thereby improving R & D to improve material technology competitiveness in the future. Let's examine the implications of investment. A total of 5 years of new research and development investment in the field of display was invested as basic research fund for 25%, 15% for applied research, and 53% for development research. In terms of development cost and development period, the basic research showed that the amount of money and the development period were shorter than that of applied research. In other words, the basic research accounted for 25% of the R & D investment and the average R & D period was only 3.2 years. As we can see from the recent development of H fiber carbon fiber, which was recently developed and entered full-scale production, we were able to succeed because of the benefits of government support for 10 years while giving the same material title differently. In order to escape from Japan's technological dependence on semiconductor and display materials in Korea, As such, basic research in the field of materials is only possible when long-term research is conducted.
The purpose of this study is to examine the relationships between fathers and children with Internet addiction. To achieve the goal, researchers chose face to face interview methods with 12 children who had been considered'at risk'with Internet addiction. More specifically, examiners conducted individual in-depth interviews with 12 children associated with Internet addiction for 30~40 minutes during four sessions through structured questions and non-structured questions. After collecting data, examiners conducted a categorical analysis based on collected data. Finally, the research results, discovered in this research, were as follows: First, the Internet set up the inter-generational barrier in the relationship between father and child, second, children took an interest in the Internet instead of their busy father, Third, the Internet played the role of a place to escape from the awkwardness with their father, fifth, fathers were not able to control the Internet use of their children. Based on the research results, this study suggests a desirable behavior pattern for fathers which can be conducive to children with Internet addiction and their fathers along with a follow-up study.
Journal of the Institute of Electronics Engineers of Korea SD
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v.37
no.5
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pp.77-87
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2000
In this paper, we propose a Over-The-Cell channel routing algorithm for the advanced three-layer process. The proposed algorithm makes the channel routing problem to simplified one and makes use of simulated annealing technique to achieve the global optimal solution. And, a new method to remove the cyclic vertical constraints which are known to be the hardest element in the channel routing problem is proposed, and a way to detect the local minimal solution and escape from it successfully is presented. Futhermore, genetic algorithm based channel router is implemented and comparison is performed with the simulated annealing based one. All algorithms are written in C++ and GUI is made using Motif under Linux environment.
This study intends to provide fundamental data to develop creative high-value designs, proving that the cut-out technique, a decorative element of fashion design, can be used to express various visual effects. The author performed a literature review of such publications as Gap Press, Fashion News, and Mode & Mode from 2001S/S to 2010S/S, referring to Internet data to empirically analyze the cut-out technique in contemporary fashion. The study found that the cut-out design is effective overall, but is best suited for one-piece designs and for partial rather than whole items of clothing. The basic motif of the cut-out is a geometrical pattern based on a line, a tear, or is shapeless. The cut-out design is mostly shown as an overall pattern or as a symmetrical shape. Analysis shows that the characteristics of the contemporary fashion utilizing the cut-out technique are as follow: First, the cut-out technique exposes the curves of a woman's body in a direct or indirect way, thereby emphasizing her sexuality and maximizing the value of female beauty. Second, through the cut-out technique, we can highlight the various types of space formed by the technique and repeated patterns; we may also elaborate on single-patterned laser-cut designs, which will show that the particular surface effect of the material can strongly impact the attractiveness of the design through emphasis and decoration. Third, damaging or destroying clothes on purpose, showing surprising concepts through optical illusions, and expressing humor by ignoring existing clothing styles show our willingness to escape from traditional or obvious design ideas, as well as demonstrating individuality and playfulness.
Journal of the military operations research society of Korea
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v.35
no.2
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pp.99-117
/
2009
Energy is essential factor of production for a firm to produce goods and services. If so, what is the condition of maintaining profit of a firm when energy price is going up? In conclusion, the condition is that the rate of productivity improvement should be greater than the rate of energy price increase. To put this concretely, when the elasticity of energy price as to the productivity improvement is greater than the weight of the energy cost on to the total revenue of the firm, the firm can escape the negative effect of energy price increase. This is that, saying that once more, the firm have to reduce the energy cost or promote energy efficiency to maintain appropriate or sufficient profit when energy price is going up fast. Therefore, in this study we will analyze the effect of the oil price increase on the energy saving investment and that of energy saving investment on the energy efficiency in the field of Korean manufacturing industry. In doing so, this study could show that the effect of energy price increase on the energy efficiency of the firm and the factor of that mechanism.
The purpose of this study was to explore what chiefs of tong/ri' experiences in suicide prevention activities are and what their changes are. The study participants are three chiefs of tong/ri who have participated in suicide prevention activities for more than two years in the community. In order to gain a deeper understanding of their respective experiences, used a qualitative method of narrative study. Chiefs of tong/ri' experiences experience in participating in suicide prevention activities consisted of start, experience, change and growth. The meaning is as follows. They did a "light start" with the idea that they could do it easily in their original activities. "Escape from the burden" of learning and maintaining each of own ways in the difficult problem of suicide prevention, "Responsibility as a chief" was the driving force behind suicide prevention activities. They were able to find "change of their own" because of the activity naturally.
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