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Effects of Melatonin on the Reproductive Endocrine System in Male Golden Hamsters (골든 햄스터의 생식내분비계에 미치는 멜라토닌의 영향)

  • 최돈찬;우대균;임시내
    • Korean Journal of Environmental Biology
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    • v.20 no.3
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    • pp.224-231
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    • 2002
  • Photoperiod (length of light per day) is a major factor in regulating reproductive function in golden hamsters. The information of photoperiod is transmitted to the reproductive endocrine system by melatonin. Thus the effects of melatonin aye investigated in male golden hamsters exposed to photoperiods. Paired testicular weights were markedly reduced in the animals housed in short photoperiod $(SP,\le{12\;hours\;day^{-1})$ and injected with melatonin in the evening, but not in long photoperiod $(LP,\le{12.5}\;hours\;day^{-1})$ and injected with melatonin in the morning. The histological examination of regressed testes showed reduction of tubular lumen diameter including the numbers of cells and Leydig cell number. The mean values of both follicle stimulating hormone (FSH) and luteinizing hormone (LH) were also lowered in the sexually inactive animals than in the sexually active animals. Melatonin receptor was identified by reverse-transcription polymerase chain reaction (RT-PCR) and its expression was examined in various tissues to scrutinize the action site of melatonin. It turned out 309 nucleotides and was definitely expressed in hypothalamus and pituitary including spleen, retina, and epididymis. And gonadotropin releasing hormone (GnRH) gene, which is a key element in regulating reproduction, was identified by RT-PCR but the expression of GnRH was not modified by the treatment of melatonin. Taken together, photoperiod via melatonin indirectly affects reproductive endocrine system, possibly through the release of GnRH, not the synthesis of GnRH.

Genetic Implications of Ultramafic Rocks from the Bibong Area in the Kyeonggi Gneiss Complex (경기편마암복합체내 비봉지역에 분포하는 초염기성암에 대한 성인적 적용)

  • Song, Suck Hwan;Choi, Seon Gyu;Woo, Jun Gie
    • Economic and Environmental Geology
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    • v.30 no.5
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    • pp.477-491
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    • 1997
  • In the Bibong area of the western part of Chungcheongnam-do, ultramafic masses occur as discontinuous isolated lenticular bodies in the Precambrian Kyeonggi gneiss complex. They extend for about 200 m long to NNE directions which are parallel to fault lines in the gneiss complex. The ultramafic masses contact with the adjacent gneiss complex as steeply dipping faults. They are dunites and harzburgites and many of them are partially or completely serpentinized. The ultramafic rocks dominantly show protogranular, equigranular and equigranular-$m{\grave{o}}saic$ textures. They also show porphyroclastic (megacrystic) or recrystallized textures reflecting several stages of metamorphism. They contain varying amounts of olivine $(Fo_{89-92})$, enstatitic to bronzitic orthopyroxene, diopsidic clinopyroxene, tremolitic to pargasitic hornblende, and spinel with serpentine, talc, chlorite, calcite and magnetite. The ultramafic rocks have high magnesium numbers and transitional element contents, low alkali contents and show deplete REE patterns. Comparing with available data, geochemical and mineralogical characteristics shown in the ultramafic rocks of the Bibong area are similar to those of worldwide mantle xenoliths and orogenic related ultramafic rocks. The field evidences, petrographical, geochemical and mineralogical characteristics shown in the ultramafic rocks of the Bibong area are similar to alpine type ultramafic rocks emplaced into the crust by the faulting as mantle slab types. With the petrographical characteristics, these mineralogical compositions suggest that the ultramafic rocks of the Bibong area have experienced several stages of retrogressive metamorphism in a condition ranging from the upper amphibolite facies to greenschist facies.

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A Study on the Characteristics of Change by Observation Area which changes as the observation time passes in Interior Space (실내공간에서 주시시간의 경과에 따른 구역별 주시특성에 관한 연구)

  • Kim, Jong-Ha;Ban, Young-Sun
    • Korean Institute of Interior Design Journal
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    • v.21 no.2
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    • pp.84-91
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    • 2012
  • The total data of observing interior space was divided into a few time frames for analysis. If we can understand the changing process of observation degree as the observation time passes, we will be able to analyse the characteristic and process of information obtainment in the case of space observation. For this purpose, the observation time was parted into 30 second units and the changing characteristic by time frame and observation area was analysed. The conclusion derived from this study is as the following: First, analysis of observation frequency and time on the basis of the average data of each subject showed that the observation time increased compared with the subject's frequency and the overall trend but that it was difficult for me to think there was a certain trend in the observation time of each subject. However, when I examined the time change by using the trend line which is a dynamic average line representing the observation time from the subjects as the trend element of time series, I could see the trend that the subject's observation time increased at a fixed rate as the frequency increased. Second, when I compared and analysed the average observation area at Area I set up by the time of 30 second unit and the observation area of Area I from the all data, I could see that the former had more degree of concentration at Area I. This analysis enabled me to get the degree of concentration on the observed area every time, and accordingly I could also see that when the data of intensive observation by time frame is analysed, the degree of concentration is dispersed for the subjects to observe very intensively or the area with overlapping observations each time frame can be seen as Area I out of the entire observation data. Third, when I analysed the observation characteristics by time frame at the 6 areas divided at 30 second unit at the rate of the number to the time of observation areas, I could see that as the observation time passed while the number of the observation areas defined as decreased the observation time increased, which means that when the area numbers decreases the area intensively observed by the subjects decreases as the time passes. In spit of that, the increase of time can be interpreted as more intensive observation of a specific area.

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Effects of Screw Configuration on Biomechanical Stability during Extra-articular Complex Fracture Fixation of the Distal Femur Treated with Locking Compression Plate (잠김 금속판(LCP-DF)을 이용한 대퇴골 원위부의 관절외 복합골절 치료시 나사못 배열에 따른 생체역학적 안정성 분석)

  • Kwon, Gyeong-Je;Jo, Myoung-Lae;Oh, Jong-Keon;Lee, Sung-Jae
    • Journal of Biomedical Engineering Research
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    • v.31 no.3
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    • pp.199-209
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    • 2010
  • The locking compression plates-distal femur(LCP-DF) are being widely used for surgical management of the extra-articular complex fractures of the distal femur. They feature locking mechanism between the screws and the screw holes of the plate to provide stronger fixation force with less number of screws than conventional compression bone plate. However, their biomechanical efficacies are not fully understood, especially regarding the number of the screws inserted and their optimal configurations. In this study, we investigated effects of various screw configurations in the shaft and the condylar regions of the femur in relation to structural stability of LCP-DF system. For this purpose, a baseline 3-D finite element (FE) model of the femur was constructed from CT-scan images of a normal healthy male and was validated. The extra-articular complex fracture of the distal femur was made with a 4-cm defect. Surgical reduction with LCP-DF and bone screws were added laterally. To simulate various cases of post-op screw configurations, screws were inserted in the shaft (3~5 screws) and the condylar (4~6 screws) regions. Particular attention was paid at the shaft region where screws were inserted either in clustered or evenly-spaced fashion. Tied-contact conditions were assigned at the bone screws-plate whereas general contact condition was assumed at the interfaces between LCP-DF and bone screws. Axial compressive load of 1,610N(2.3 BW) was applied on the femoral head to reflect joint reaction force. An average of 5% increase in stiffness was found with increase in screw numbers (from 4 to 6) in the condylar region, as compared to negligible increase (less than 1%) at the shaft regardless of the number of screws inserted or its distribution, whether clustered or evenly-spaced. At the condylar region, screw insertion at the holes near the fracture interface and posterior locations contributed greater increase in stiffness (9~13%) than any other locations. Our results suggested that the screw insertion at the condylar region can be more effective than at the shaft during surgical treatment of fracture of the distal femur with LCP-DF. In addition, screw insertion at the holes close to the fracture interface should be accompanied to ensure better fracture healing.

A Study of Sloshing Tank on Vessel Motions with Various Baffle Clearance (탱크 내 격벽에 의한 간극 변화가 선박 운동에 미치는 영향 연구)

  • Kim, Kyung Sung;Yu, Sunjin
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.24 no.6
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    • pp.796-802
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    • 2018
  • The effects of inner liquid sloshing on vessel motions are a well-known factor. It was investigated experimentally and numerically. In this regard, the study of many efforts to reduce natural phenomena of vessel motions by adopting special devices especially for roll motions. Among many devices, inserting baffles in the inner liquid tank is very common. In this study, one investigated the vessel motions with inner sloshing tanks with baffles inside. For the numerical simulation, one employed a dynamically coupled program between boundary-element-method-based vessel motion analysis program and a particle-based computational fluid dynamics program. Comparing corresponding experimental results validated the dynamically coupled program. The validated coupled program was used to simulate vessel motions, including sloshing effects with various lengths of inner baffles. The simulation results show that not only the filling ratio of inner liquid, but also the length of clearance due to baffles influenced the vessel motions. The significant point of this study was that the natural frequency of vessel motions can be maintained irrespective of the amount of filling ratio through adjustment of the clearance. In a future study, the effects of various numbers of baffles with various clearances would be conducted to percuss the possibility of vessel motion control with inner liquid sloshing effects.

Vibration Control of Mega Frame Structures using a Semi-active Tuned Mass Damper (준능동 TMD를 이용한 메가골조구조물의 진동제어)

  • Kim, Hyun-Su;Lee, Dong-Guen
    • Journal of the Earthquake Engineering Society of Korea
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    • v.11 no.2 s.54
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    • pp.57-68
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    • 2007
  • The mega frame system is becoming popular for the design and construction of skyscrapers because this system exhibits structural efficiency by allowing high rigidity of the structure while minimizing the amount of structural materials to be used. Since the mega frame system is usually adopted for super high-rise buildings, the comfort of occupants may be main concerns in the practical application of this system. For the enhancement of the serviceability of mega frame structures, a semi-active tuned mass damper (STMD) is developed in this study. To this end, a Magnetorheological (MR) damper is employed replacing passive damper as a semi-active damper to improve the control effect of a conventional TMD. Since a conventional finite element model of mega frame structures has significant numbers of DOFs, numerical simulation for investigation of control performances of a STMD is impossible by using the full-order model. Therefore, a reduced-order system using minimal DOFs, which can accurately represent the dynamic behavior of a mega frame structure, is proposed in this study through the matrix condensation technique To improve the efficiency of the matrix condensation technique, multi-level matrix condensation technique is proposed using the structural characteristics of mega frame structures. The efficiency and accuracy of the reduced-order control proposed in this study and the control performance of a STMD were verified using example structures.

A Numerical Method for Nonlinear Wave-Making Phenomena (비선형 조파현상의 수치해법)

  • Jang-Whan Kim;Kwang-June Bai
    • Journal of the Society of Naval Architects of Korea
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    • v.30 no.1
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    • pp.65-72
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    • 1993
  • A numerical method for nonlinear free-surface-wave problem is developed in this paper. The final goal of this study is to simulate the towing tank experiment of a ship model and to partially replace the experiment by the numerical model. The exact problem in the scope of potential flow theory is formulated by a variational principle based on the classical Hamilton's principle. A localized finite element method is used in the present numerical computations which made use of the following two notable steps. The first step is an efficient treatment of the numerical radiation condition by using the intermediate nonlinear-to-linear transition buffer subdomain between the fully nonlinear and linear subdomains. The second is the use of a modal analysis in the final stage of the solution procedures, which enables us to reduce the computation time drastically. With these improvements the present method can treat a much larger computational domain than that was possible previously. A pressure patch on the free surface was chosen as an example. From the present computed results we could investigate the effect of nonlinearity on the down-stream wave pattern more clearly than others, because much larger computational domain was treated. We found, specifically, the widening of the Kelvin angle and the increase of the wave numbers and the magnitude of wave profiles.

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Macroscopic Analysis of Traffic Flow in the Korean Coastal Waterway (한국연안의 해상교통류분석(I))

  • 이철영;문성혁;최종화;박양기
    • Journal of the Korean Institute of Navigation
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    • v.10 no.2
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    • pp.31-55
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    • 1986
  • Generally, the development of shipping is characterized by the amount of traffic flow (traffic volume) and seaborne cargo in the sea. Movement of ships is an essential element of constructing the traffic flow which is represented the dynamic movement of ships in the sea, but on the other band the numbers of arriving and departing the port is the basic factor consisting of the static movement of ships. The amount of cargoes by coastal vessels and ocean trade vessels have increased tremendously with the great growth of the Korean economy these days. This increase of the seaborne cargoes has made the Korean coastal traffic flow so congested that this can be a cause of large pollution as well as great marine casualities such as a loss of human lives and properties . And also the future coastal traffic is expected to increase considerably according to our economic development and high dependence upon foreign trade. Under the circumstance, to devise the safety of coastal traffic flow and to take a proper step of a efficient navigation, there is a necessity for analyzing and surveying the coastal traffic trend and the characteristics of cargo movement. In order to grasp the dynamic movement of ships in the Korean coast, O/D analysis is executed. This paper aims to secure the basic data necessary for a comprehensive plan and estimation of vessel traffic management system for the enhancement of safety, order and efficiency of vessel traffic in the Korean coast. The analyzed results of the traffic flow and seaborne cargoes of the Korean coast are summarized as follows : 1) The congestion by the vessels occurred around the ports such as-in proportion of ship's number (proportion of tonnage) -Incheon 18.5%(14.8%), Pohang 5.9% (9.9%), Samil 5.2%(8.3%), Mokpo 8.6%(0.8%), Pusan 13.5%(36.4%), Ulsan 9.1%(16.2%). 2) It is found that the area adjacent to Incheon, Pusan, Ulsan, Channel of Hanryu and South-western area are heavily congested. 3) It is confirmed thatthe area adjacent to Incheon, Pusan, Ulsan, Channel of Hanryu and South-western area are heavily congested. 3) It is confirmed that the coastal vessels are main elements constituting the coastal traffic and that there are much traffic flow among five ports as following through the precise O/D analysis of ship's coastal movement. Incheon-Samil, Ulsan, Pusan, Jeju Pusan -Samil, Ulsan, Incheon, Jeju Pohang -Samil, Inchoen, Jeju Pohang -Samil, Incheon, Jeju Ulsan -Samil, Incheon, Jeju Samil -Ulsan, Pusan, Incheon 4) The amount of cargoes to abroad are in proportion about 81% of total and the amount of coastal cargoes are about 19%. Of those, cargoes in and out to Japan are about 26% and to South-east Asia are about 27%. 5) The chief items of foreign cargoes are oil(38.33%), iron ore(13.98%), bituminoous coal(12.74%), grain(8.02%), lumber(6.45%) in the import cargoes and steel material(21.96%), cement(17.16%), oil(6.81%), fertilizer(3.80%) in the export cargoes. 6) The 80.5% of total export cargoes and 92.4% of total import cargoes are flowed in five main ports. 7) The chief items of coastal cargoes are oil (42.45%), cement(16.86%), steel material (6.49%), anthracite(6.31%), mineral product(4.3%), grain, and fertilizer. Almost 92.24% of total import and export oil cargoes in Korea is loaded and unloaded at the port of Samil & Ulsan.

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A Study on the Communication of the Functional Family (기능적인 가족의 커뮤니케이션에 관한 이론적 접근)

  • 조윤경
    • Journal of Families and Better Life
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    • v.2 no.1
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    • pp.131-150
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    • 1984
  • The purpose of this study is to explore the family as an interaction system, concentrating on the mutual influences between communication and family development; (1) how Communication patterns affect family relationships, and (2) how relationships among family members affect communication. In order to do this Galvin, Brommel used the following frame work; family is a system in which communication regulates cohesion and adaptability by a flow of message patterns through a defined network of evolving interdependent relationships. A family system consists of members, the relationships among them, the family attributes, the members attributes and an environment in which family functions. Within the framework of common cultural communication patterns, each family has the capacity to develop its own communication code based on the experiences of individual members and the collective family experience. Most of us develop our communication skills within the family context learning both the general cultural language and the specific familial communication code. Communication may be viewed as a symbolic, transactional process as the process of creating and sharing meanings. To say that communication is a process implies a continuous interaction of an indefinite large numbers of variables with a concomitant,. continuous change in the values taken by these variables. Finally the process implies change, Family functions include the primary functions of cohesion and adaptability, and supporting functions of family images, themes, boundaries, and biosocial issues. The primary functions reveal concepts integrated family interaction and supporting function, along with those of cohesion and adaptability, give shape to family life. the characteristics of developed relationships of richness, uniqueness efficiency, substitutability, pacing , openness spontaneity, and evaluation are reflected in the verbal and nonverbal behaviors with which family members negotiated a set of common meanings and develop thier own unique message system. The message system is the major element of communication process and influences both the form and the content of thier relationship and in create and share meanings. Family systems need to provide order and predictability for thier members, specifically focusing on communication rules and the networks by which messages are transmitted. Most rules emerge as a result of multiful interactions. There are basic rules and rules about rules, or metarules. Perceiving the rules of family system is very difficult because often family members don't think about the basic rules, much less the metarules. Breaking the rule may result in the creation of a new set because the system may recalibrate itself to accept more variety of behavior. Families develop communication networks to deal with the general issue. Family adaptability may be seen through the degree of flexibility in forming and reforming networks and networks become a vital part of the decision- making process and relate to the power dynamics operating within the family. Networks also play an integral part in maintaining the roles and rules operating with the family system. Thus networks and rules have mutual influence. The family -of -origin issues influence all aspects of family communication and account for many of the communication patterns, rules and networks and the role of the family -of-origin influences as a primary force for communication on behavior of newly forming systems. Each family system develops its own communication meanings. There is not one right way to communicate within a family but may be indefinitly large change of family life and communication behavior. Study on functional family communication helps to gain a better understanding of dynamics of family communication and ability of a new insight into the family.

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Characteristics for Horizontal Displacement of Temporary Earth Retaining Wall on Marine Sediments (해성퇴적층 지반의 가시설토류벽 수평변위 특성에 관한 연구)

  • Kim, Younghun;Kim, Chanki;Choi, Sungyeol;Chun, Byungsik
    • Journal of the Korean GEO-environmental Society
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    • v.11 no.11
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    • pp.37-45
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    • 2010
  • In this study, the value of numerical analysis was compared to the measured value of horizontal displacement during construction. And also, the value was reviewed by comparing with numbers calculated by SUNEX program and EXCAV program. When comparing to suggested values of the maximum horizontal displacement in clayey layer, the displacement caused by the IPS system is larger than one by the Strut girder type system. When comparing the result of SUNEX program to that of EXCAV program, the SUNEX program interprets larger value. It could be concluded the result of SUNEX program is closer to the suggested value, 0.5%H, in clayey layer. The result also shows that the internal friction angle(${\Phi}$) is the key factor of developing horizontal displacement rather than type of supporting systems or materials. That means small horizontal displacement occurs in sandy layer having large value of the internal friction angle, whereas vice versa in clayey layer having small value of the internal friction angle. Therefore, the result of EXCAV program is larger in sandy layer and vice versa in clayey layer. When comparing the measured result during construction to the value of 0.5%H, the measured result is 1.4 times greater than the value of 0.5%H. In contrast, the result of SUNEX program is only 78.1% of the value of 0.5%H and the one of EXCAV program is just 18.1% of that. This result shows the calculated value by SUNEX or EXCAV program is smaller than the observed value by measuring during construction. In result, more careful attention is needed to determine the behavior of the ground. To better analyze the behavior of the ground, more precise finite element method is required.