• Journal of the Korean Chemical Society
• /
• v.55 no.5
• /
• pp.776-780
• /
• 2011

A mild and efficient procedure for the synthesis of various 1,5-benzothiazepines were developed. This method provides an easy access for preparation of 1,5-benzothiazepine derivatives in the presence of 10 mol% catalyst of CAN under ultrasonic irradiation. This method provided clean conversion, mild reaction condition, no use of toxic solvent and shorter reaction time compared to other reported method.

• Bulletin of the Korean Chemical Society
• /
• v.33 no.12
• /
• pp.4127-4130
• /
• 2012

We report a fast, efficient, and facile route for the synthesis of 2,5-dihydro-5-imino-2-methylfuran-3,4-dicarboxylate derivatives from the isocyanide, dialkyl acetylenedicarboxylate and acetic anhydride under ultrasound-assisted conditions. Utilization of easy reaction conditions, very high to excellent yields, and short reaction times makes this manipulation potentially very useful.

• Journal of the Korean Chemical Society
• /
• v.55 no.5
• /
• pp.781-786
• /
• 2011

An easy and efficient route for the synthesis of some imidazo[1,2-c]pyrazolo[4,3-e]pyrimidines 3-6, imidazo[1,2-c]pyrazolo[4,3-e]triazine 8, pyrazolo[4,3-e]triazolo[1,5-c]pyrimidines 12-15 and pyrazolo-[3',4':4,5]pyrimido[1,6-b]triazines 16, 17 was described through the reaction of readily available 5-aminopyrazole-4-carbonitrile 1 with different reagents. The in vitro antimicrobial activity of some synthesized compounds was examined. Most of the tested compounds proved to be active as antibacterial and antifungal agents.

• Journal of the Korean Society of Manufacturing Process Engineers
• /
• v.10 no.4
• /
• pp.109-114
• /
• 2011

An impeller is difficult to machine because of severe collision due to the complex shape, overlapping and twisted shape that form impeller blades. So, most CAM software companies have developed CAM module for manufacturing impeller in addition to their CAM software. But it is not still easy for inexperienced users to machine impellers. The purpose of this paper is the development of automatic CAM module for manufacturing impeller(E-ICAM) which is based on visual basic language and it is used CATIA graphical environment in order to be easily machining impellers. Automatic CAM module for manufacturing of impellers generates tool path, and proposes recommended cutting condition according to the material of stock and tool. In addition, it has also included a post processor for 5-axis control machining. Therefore the user can easily machine impellers using this automation module.

• Bulletin of the Korean Chemical Society
• /
• v.34 no.5
• /
• pp.1508-1512
• /
• 2013

A simple and efficient synthesis of 2,4,5-trisubstituted imidazoles was achieved via a one-pot three-component cyclocondensation of benzil, aromatic aldehydes, and ammonium acetate in the presence of a catalytic amount of tetrabutylammonium hexatungstate $[TBA]_2[W_6O_{19}]$ as a heterogeneous catalyst under thermal solvent-free conditions. The key features of this methodology are operational simplicity, high yields, short reaction times, and a recyclable catalyst with a very easy work up.

• Analytical Science and Technology
• /
• v.22 no.5
• /
• pp.355-359
• /
• 2009

An enzyme electrode bound by rubber solution was newly constructed and the test of its practicability were carried out. The binder of carbon powder was styrene-butadiene rubber dissolved in toluene and enzyme source was ground tissue of cabbage root. Volatilization of the solvent made the electrode material possess a mechanical robustness and a fast signal appearance. The electrode showed electrochemically irreversible characteristics and a powerful catalytic power (detection limit=$5.0{\times}10^{-5}M$, S/N=2). The double reciprocal plot of signal current and substrate concentration was ideally linear and the symmetry factor and exchange current density of the electrode used in this work were 0.35 and $4.93{\times}10^{-5}Acm^{-2}$ respectively.

• The Transactions of The Korean Institute of Electrical Engineers
• /
• v.65 no.6
• /
• pp.1083-1088
• /
• 2016

25.8kV GIS part generated by sensors to measure contact an inflow of noise depending on the extent of the measured discharge occurs often not easy. Partial discharge signal measurement sensor suitable for developing a more useful measurements at the scene to this, partial discharge waveform analysis developed a sensor, and to utilize forSensor on the development of the most important is VSWR decided to (voltage standing wave ratio) voltage standing-wave ratio less than 1.5 and decided less than at the full spectrum bands that are measured, this time Return loss, as measured value by absolute criteria 14.0 dB produced the sensor, designed to or more. UHF 1.5~0.5 GHz bandwidth spectrum to be measured in GIS. UHF bands were designed to be able to measure the best signal. Recently, 25.8kV GIS production company has been increasing variety of GIS were made open spacer in partial discharge in accordance with the not very easy to detect the signal. The sensor is designed height of four cm external spacer is attachment GIS in an influx of outside noise measurement, and be so manufactured as to facilitate the least we've done. Also, since partial discharge which occur can measure the frequency of the 170kV GIS external partial-discharge signals that occur at the scene of insulation applied to the spacer. Features, and also derived good results using global positioning. Also measured discharge point about sensors that are stable and the reliability of the development and local substation equipment failure occurring signal analysis through the discharge for the prevention of widely. There should be to believe that used.

• Korean Journal of Community Nutrition
• /
• v.16 no.3
• /
• pp.307-314
• /
• 2011

The purpose of this study is finding the easy way of 4 categories activity level confirmation for estimated energy requirement calculation. Total of 386, 5th and 6th grade primary school students participated. The time spent on 7 kinds of activity were collected for 1 day by the internet program developed. Judged by the activity coefficient, sedentary were 6.7% and 5.1%, low active 33.2% and 40.4%, active 43.8%, and45.5%, and very active 16.3% and 9.0% for boy and girl, respectively. The highest and significant correlation coefficient between activity coefficient and time spent on activities shown were 0.339 in commute activity for boys, and 0.466 in leisure for girls. The sensitivity of the sedentary conformation by commute hour for boys was 0.79, and that of very active was 0.56. The sensitivity of the sedentary conformation by leisure hour for girls was 0.67, and that of very active was 0.63. The sensitivity of low active and active by 7 different types of activity was quite low, 0.04~0.37. The exact agreement of activity level conformed by easy way developed was 30.8% and 33.7%, for boys and girls, respectively. More accurate way to identify 4 categories activity level needs to be developed, especially sensitive to conformation of low active and active levels.

• Asian-Australasian Journal of Animal Sciences
• /
• v.18 no.1
• /
• pp.90-95
• /
• 2005

Lactic acid bacteria were isolated from silage, which produce high level of hydrogen peroxide in cell culture supernatant. The 16S rDNA sequences of the isolate matched perfectly with that of Lactobacillus fermentum (99.9%), examined by a 16S rDNA gene sequence analysis and similarity search using the GenBank database, thus named L. fermentum CS12-1. L. fermentum CS12-1 showed resistance to low pH and bile acid. The production of hydrogen peroxide by L. fermentum CS12-1 was confirmed by catalase treatment and high-performance liquid chromatography. L. fermentum CS12-1 accumulated hydrogen peroxide in culture broth as cells grew, and the highest concentration of hydrogen peroxide reached 3.5 mM at the late stationary growth phase. The cell-free supernatant of L. fermentum CS12-1 both before and after neutralization inhibited the growth of enterotoxigenic Escherichia coli K88 that causes diarrhea in piglets.

• Journal of Korean Academy of Nursing
• /
• v.39 no.6
• /
• pp.781-787
• /
• 2009

Purpose: The purpose of this study was to evaluate a computerized touch-screen version of the asthma-specific quality-of-life (cA-QOL) questionnaire against the conventional paper-and-pencil version (pA-QOL) for equivalence, time for completion, user preference, and ease of use. Methods: A total of 261 patients were recruited. A randomized cross-over design was used. Patients in group A completed the cA-QOL first while waiting to see a physician, and completed the pAQOL version after seeing the physician. Patients allocated in group B completed these questionnaires in the reverse order. The patients were asked questions about user preference and ease of use of the cA-QOL. The time taken to complete both versions of the questionnaire was measured. Results: Weighted kappa coefficients of all items showed almost perfect agreement. The time required to complete the pA-QOL is faster than the time for cA-QOL. The patients who preferred the cA-QOL were 37.5%, while those who preferred the pA-QOL were 29.9%. Most patients reported that the cA-QOL was "easy" or "very easy" to complete. Conclusion: The cA-QOL is the computerized equivalent of the pA-QOL. The findings herein demonstrate that the cA-QOL can be helpful to nurses in busy practices for assessing, collecting, and evaluating their patients' health related quality of life.