[KSCI] Korea Science Citation Index Service

http://dx.doi.org/10.5012/jkcs.2011.55.5.781

Facile Synthesis of New Pyrazolopyrimidine Derivatives of Potential Biosignificant Interest

Aly, Aly A. (Chemistry Department, Faculty of Science, Benha University)
El-Karim, Iman A. Gad (Chemistry Department, Faculty of Science, Benha University)

Publication Information

Journal of the Korean Chemical Society / v.55, no.5, 2011 , pp. 781-786 More about this Journal

Abstract

An easy and efficient route for the synthesis of some imidazo[1,2-c]pyrazolo[4,3-e]pyrimidines 3-6, imidazo[1,2-c]pyrazolo[4,3-e]triazine 8, pyrazolo[4,3-e]triazolo[1,5-c]pyrimidines 12-15 and pyrazolo-[3',4':4,5]pyrimido[1,6-b]triazines 16, 17 was described through the reaction of readily available 5-aminopyrazole-4-carbonitrile 1 with different reagents. The in vitro antimicrobial activity of some synthesized compounds was examined. Most of the tested compounds proved to be active as antibacterial and antifungal agents.

Keywords

Imidazole pyrimidine; Pyrazole and triazine;

Citations & Related Records

Times Cited By SCOPUS : 2

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