• Title/Summary/Keyword: Early Assessment

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Gene Expression Profiling in the Nematode Caenorhabditis elegans, as a Potential Biomarker for Soil Ecotoxicology (잠재적 생체지표 발굴을 위한 토양선충 Caenorhabditis elegans에서의 유전자 발현 연구)

  • Roh, Ji-Yeon;Choi, Jin-Hee
    • Environmental Analysis Health and Toxicology
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    • v.25 no.1
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    • pp.1-10
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    • 2010
  • Monitoring toxicity levels in specific biological compartments is necessary to evaluate the ecotoxicological risk associated with soil environmental pollution. Gene expression, as potential biomarker, is increasingly used as rapid early warning systems in environmental monitoring and ecological risk assessment procedures. Various representative species are currently used for the purpose of assessing soil toxicity, however, investigations on toxicological assessments using endpoint based on gene-level have been limited. In this review, we will present the current trends in organisms and endpoints used in soil toxicity study and report gene expression related to toxicity using soil organism, and C. elegans as promising organisms for this approach.

Sensors, smart structures technology and steel structures

  • Liu, Shih-Chi
    • Smart Structures and Systems
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    • v.4 no.5
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    • pp.517-530
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    • 2008
  • This paper deals with civil infrastructures in general, sensor and smart structure technology, and smart steel structures in particular. Smart structures technology, an integrated engineering field comprising sensor technology, structural control, smart materials and structural health monitoring, could dramatically transform and revolutionize the design, construction and maintenance of civil engineering structures. The central core of this technology is sensor and sensor networks that provide the essential data input in real time for condition assessment and decision making. Sensors and robust monitoring algorithms that can reliably detect the occurrence, location, and severity of damages such as crack and corrosion in steel structures will lead to increased levels of safety for civil infrastructure, and may significantly cut maintenance or repair cost through early detection. The emphasis of this paper is on sensor technology with a potential use in steel structures.

A Study on the RAMS Activities and Practices for assuring Safety of the Centralized Traffic Control System of Urban Railway (도시철도관제시스템 안전성 확보를 위한 RAMS 활동 및 그 적용사례에 관한 연구)

  • Choi, Yo Chul
    • Journal of the Korean Society of Systems Engineering
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    • v.10 no.2
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    • pp.43-50
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    • 2014
  • The Centralized Traffic Control(CTC) System of Urban Railway is an element(subsystem) of the Urban Railway system to aim safety operation and efficient management of rolling stock in accordance with a train scheduling program in train operation ways. That's why the CTC System must be developed considering systematic and safety-guaranteed methods such as RAMS(Reliability, Availability, Maintainability, and Safety) refereed to IEC standards. The CTC System is consists of rolling stock, signaling, power supply, communication, and mechanical equipment and preforms control and remote monitoring functions. The technical activities considering safety process are very important at such an early stage of development in a railway project. This paper introduces RAMS activities and an independent safety assessment by $3^{rd}$ Party focused on a safety applied to a development of the CTC system of Urban Railway and proposes the experiences as well practices.

A Study on the Assessment of Optimum Berth Length for Incheon Container Terminal of the Kyeong-In Port (경인항 인천컨테이너터미널의 최적 부두길이 산정에 관한 연구)

  • Kim, Se-Won;Park, Young-Soo;Kim, Tae-Min
    • Journal of Fisheries and Marine Sciences Education
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    • v.23 no.2
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    • pp.210-220
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    • 2011
  • The Keyongin Inland waterway will connect with Han-River and the Northen part of the Incheon-seaway and this way will be opened at the early of October this year. In this regard, the Incheon container terminal is under constructing for 1,000 TEU & 550 TEU container vessels at the place of leftside of the Seohae lockgate. However the terminal length is not still fixed due to at a great expenses of construction and dosposal matter of the dredged soil. So this paper will suggest the optimum berth length by using the full mission shiphandling simulator for berthing and unberthing shipmaneuvering. And also evaluates the design standard of harbor construction rules and analysis optimum berth length against ship's length for safe shiphandling at terminals in accordance with the customary practices of the major ports in Korea.

Relations Between Infant Temperament by Caregivers' Perceptions and Infant-Caregiver Interactions (영아기질에 대한 양육자의 지각 차이 및 기질과 양육자와의 상호작용 관계)

  • Park, Soo-Bin;Kim, Sook-Ryong
    • Korean Journal of Child Studies
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    • v.26 no.3
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    • pp.1-13
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    • 2005
  • Subjects were 78 12- to 35- month old infants, their mothers, and their teachers. Instruments included the Revised Toddler Temperament Questionnaire(Y. H. Choi 1990) and the Assessment Profile for Early Childhood Programs(M. K. Hong 1997; S. K. Kim 1999). There was no significant difference in perceptions of infant temperament between mothers and teachers. Infant-mother interaction differed by infant temperament in that mothers had high scores with easy infants but low scores with difficult children. On the other hand teachers maintained high interactions with difficult infants in the case of infant's rhythmicity. Infant-teacher interaction correlated with such teacher variables as teacher-infant ratio, teachers' academic backgrounds and working hours.

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The Effects of a Literary Approach Activity Using a Game Strategy on Young Children's Phonological Awareness Abilities and Writing Abilities (게임전략을 활용한 문학적 접근활동이 유아의 음운인식능력 및 쓰기능력에 미치는 영향)

  • Jeon, Ah-Young;Choi, Mi-Sook
    • Korean Journal of Child Studies
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    • v.33 no.5
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    • pp.1-17
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    • 2012
  • The purpose of this study was to examine the effects of the literary approach using a game strategy on young children's phonological awareness and writing abilities. The subjects were selected from two classes of 'H' and 'M' Kindergarten in G city. The research tools used were the Phonological Awareness Ability Test, which was corrected by Jo, Kim, and Jeong(2006) and used to measure young children's phonological awareness abilities, and Lindberg(1987)'s Kindergarten Writing Assessment which was adapted and used by Noh(1994) in order to assess writing abilities. The literary approach activity using a game strategy used in this study resulted in an improvement in young children's phonological awareness abilities and writing abilities. These results suggest that these activities are valuable tools and can be applied successfully in the childhood education field as teaching aids.

Metastasis Related Gene Exploration Using TwoStep Clustering for Medulloblastoma Microarray Data

  • Ban, Sung-Su;Park, Hee-Chang
    • 한국데이터정보과학회:학술대회논문집
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    • 2005.10a
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    • pp.153-159
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    • 2005
  • Microarray gene expression technology has applications that could refine diagnosis and therapeutic monitoring as well as improve disease prevention through risk assessment and early detection. Especially, microarray expression data can provide important information regarding specific genes related with metastasis through an appropriate analysis. Various methods for clustering analysis microarray data have been introduced so far. We used twostep clustering fot ascertain metastasis related gene through t-test. Through t-test between two groups for two publicly available medulloblastoma microarray data sets, we intended to find significant gene for metastasis. The paper describes the process in detail showing how the process is applied to clustering analysis and t-test for microarray datasets and how the metastasis-associated genes are explorated.

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SONOGRAPHIC CHANGE OF MANDIBULAR DISTRACTION OSTEOGENESIS (하악골 신장술의 초음파적 변화)

  • Kim, Chul-Hwan
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.33 no.4
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    • pp.297-306
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    • 2007
  • Distraction osteogenesis was pioneered by Ilizarov in the treatment of injured extremities. Its subsequent application to Oral and Maxillofacial Surgery has opened a new chapter in the treatment of facial deformity. Careful monitoring of the period of distraction and consolidation of the callus is important and has been well described. Complications, such as infection, haematoma and premature ossification, are difficult to diagnose and can compromise the outcome after the surgery. Too slow rate of distraction results in premature fusion of cortices and too rapid information of bone 'cyst' within the callus distraction. I experienced 2 patients of congenital unilateral mandibular hypoplasia, so called Hemifacial Microsomia. After distraction surgery, I evaluated callus formation of mandibular distraction with Ultrasound Sonography during distraction and consolidation period. Plain radiography, although it enables accurate measurement of the distraction gap, did not give sufficient detail to allow assessment of early stages of bone formation, But, ultrasound monitoring could enable continuous monitoring of the distraction gap without exposure to ionizing radiation and allow detection of fine detail, which may influence manipulation of the callus.

Steam Generator Management Program (원전 증기발생기 관리프로그램)

  • Cho, Nam-Cheoul;Kim, Moo-Soo;Lee, Kwang-Woo
    • Proceedings of the KSME Conference
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    • 2003.04a
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    • pp.610-616
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    • 2003
  • Recently, the common concern of nuclear power industry in the development of technology mitigating and preventing the aging of steam generator tubes prevails, because the trends of steam generator flaws at Uljin unit #1,2 and KSNP(Korea Standard Nuclear Power Plant) impose a burden on the operation of nuclear power plant. While the regulatory agency is demanding the establishment of the advanced general performance maintenance system, the steam generator management program adapting advanced technology is being developed which may comply with EPRI PWR SG Guidelines based on NEI 97-06 ‘ General Guidelines including all the maintenance aspects consist of the tube integrity assessment criteria, repair limit, allowable leakage level, water chemistry will be composed in order to obtain the approval of regulatory agency and be applied to Nuclear power plant early 2005. This presentation is to introduce maintenance state including SG tube degradation and main contents of advanced SG management program being developed, and futhermore update present and future plan, and estimate the alternation after the completion.

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