• Title/Summary/Keyword: E2E

Search Result 46,507, Processing Time 0.077 seconds

Effects of Estradiol-17β on the Feminization of Japanase Eel, Anguilla japonica (극동산 뱀장어, Anguilla japonica 자성화에 미치는 estradiol-17β 유도 효과)

  • Kim, Dae-Jung;Lee, Bae-Ik;Kim, Kyung-Kil;Kim, Eung-Oh;Son, Maeng-Hyun;Seong, Ki-Baik
    • Journal of Life Science
    • /
    • v.23 no.8
    • /
    • pp.998-1003
    • /
    • 2013
  • The effects of oral administration of estradiol-$17{\beta}$ (E2) on glass eels (Body weight: $0.16{\pm}0.05g$, Total length: $6.2{\pm}0.9cm$) and young eels (Body weight: $2.6{\pm}0.6g$, Total length: $13.2{\pm}0.6cm$) on gonadal sex and growth were examined, respectively. Glass eels were fed a diet containing E2 at a dose of 10 mg/kg or 25 mg/kg, respectively, for five months. The female ratio significantly increased in all E2-treated groups (10 mg/kg diet group: 70%; 25 mg/kg diet group: 90%) when compared to the control group (10%). Young eels were fed a diet containing E2 at a dose of 25 mg/kg for four months. The female ratio also significantly increased in the E2-treated groups (60%) compared to the control group (20%). The highest female ratio was observed in the stage of glass eels rather than young eels. In all experiments, however, the growth of eels treated with E2 was similar to that of controls to the end of the experiment. Thus, oral administration of E2 could be a good approach to controlling sex differentiation.

Kinematic Variables Comparison of Setter Toss Motion on Volleyball According to Toss Types (배구경기 세터 토스 동작의 운동학적 비교분석)

  • Chung, Nam-Ju;Kim, Jae-Pil
    • Korean Journal of Applied Biomechanics
    • /
    • v.25 no.1
    • /
    • pp.57-64
    • /
    • 2015
  • Purpose : The purpose of this study was to analyze setter toss motion kinematically according to toss types. Method : Dependent variables were elapsed time, vertical displacement of the body center, the projected speed of the ball, and differences of the joint angle to the target for four setters positioning. Result : There was no significant difference in the time but the ball contact time was shorter when the toss distance of P3 was longer. There was significant difference in the vertical displacement of COM (p<.05). The vertical displacement of COM showed that the vertical movement gradually decreased when the quick distance was longer. The vertical displacement of COM was difference (p<.05), also there was difference of the ball speed (p<.001) at the Release point(E4). There was significant difference in the knee joint angle at a certain moment among the Release(E4) and Landing point(E5)(p<.05). The hip joint was significant difference among the Apex(E2), Ball Touch(E3), Release(E4), and the Landing point(E5) on the surface(E2, E3, E4 p<.05; E5 p<.005). The shoulder angle was significant difference among the Ball Touch(E3), Release(E4) and the Landing point(E5) on the surface(E3, E4 p<.05; E5 p<.001). The elbow was significant difference in the Apex(E2) (p<.05). The wrist was significant difference in the Release(E4) (p<.05). Conclusion : If we find the clue to expect the direction of the setter's ball, we have to fine the clues in the Apex(E2) that hip join and elbow, Ball Touch(E3) that hip joint and shoulder joint, Release(E4) that wrist, elbow, hip joint, and knee joint.

A Study on the Stability of Uncontinuous Plate Structures with Cracks (결함을 갖는 불연속평판 구조물의 안정성 연구)

  • Lee, Seon-U;Kim, Si-Yeong;Hong, Bong-Gi
    • Journal of the Korean Society of Fisheries and Ocean Technology
    • /
    • v.20 no.1
    • /
    • pp.37-42
    • /
    • 1984
  • This paper deals with the characterics of the stability of uncontinuous plate structures with cracks. The relation between the J-intergal of the cracks existing in the stress-concentrated regions and local strain are investigated experimentally and theoretically. The BEM(boundary element method)analysis and test results lead to the follow conclusions: 1. A non-dimensional J was computed in a plate stress and strain condition for several kind of loads and crack types. The J design curves are defined as follows: J sub(E)/$\sigma$ sub(y) super(2) a=3.345(e/e sub(y) ) super(2) at e/e sub(y)$\leq$1 J sub(E)/$\sigma$ sub(y) super(2) a=3.345(e/e sub(y) ) at e/e sub(y)$\geq$1 2. Use of this curve provides a good estimation for the uncontinuous plate structures with cracks existing in the stress and strain concentrated region. 3. The stability of the characteristics is mainly depenent upon not the length of cracks but the type of the cracks.

  • PDF

Intratypic Variants of HPV-16 E6jE7 Oncogene Isolated from Sexually High-Risk Women in Busan. (부산지역 유흥업소 종사여성으로부터 분리된 HPV16형의 발암유전자(E6/E7) 돌연변이 유형 분석)

  • Min, Sang-Kee;Kim, Sung-Soon;Choi, Byeong-Sun;Jang, Dai-Ho;Lee, Mee-Ok;Choi, Seung-Hwa;Kim, Nam-Ho;Park, Yon-Koung;Jeong, Yeong-A;Kim, Seong-Joon;Bin, Jae-Hun;Park, Ho-Kuk
    • Journal of Life Science
    • /
    • v.19 no.6
    • /
    • pp.765-769
    • /
    • 2009
  • Recent studies have reported that the distribution of HPV-16 sequence variation differs geographically, and more specifically that HPV-16 E6/E7 intratypic variants might carry a high risk for development of ICC (invasive cervical cancer) and CIN (cervical intraepithelial neoplasia) in a given population. To investigate the genetic diversities of HPV-16 E6/E7 oncogene by region, we collected nineteen HPV-16 isolates from sexually high-risk women in Busan, and analyzed the HPV-16 E6/E7 coding regions (nt 34 to 880) with HPV-16 E6/E7 specific PCR amplification. At the nucleotide levet eleven variants of the E6 genes and nine variants of the E7 genes were identified as follows: E6 T178G (n=l1), E6 T178A (n=l), E6 T350G (n=3), E6 A442C (n=2), E6 AI04T, E6 All1G, E6 C116T, E6 G145T, E6 T183G, E6 C335T, E6 G522C and E7 A647G (n=12), E7 A645C, E7 A777C, E7 G663A, E7 T732C, E7 T760C, E7 A775T, E7 T789C and E7 T795G, respectively. At the amino acid levet the isolated HPV-16 E6 and E7 genes showed eleven E6 variants: E6 D25E (n=12), E6 L83V (n=4), E6 E113D (n=2), E6 MIL, E6 Q3R, E6 P5S, E6 Q14H, E6 D25N, E6 127R, E6 H78Y, E6 C140S and three E7 variants: N29S (n=12), L28F, T72S. HPV16 E6 L83V, the dominant variant in the Caucasian population, showed relatively low frequencies in our study population. We elucidated that the dominant HPV-16 E6/E7 variants were HPV-16 E6 D25E (63.2%) and HPV-16 E7 N29S (63.2%), which were phylogenetically included in Asian lineage. Further study is needed to evaluate the risk of cervical cancer related HPV-16 E6/E7 intratypic variants in the Korean population.

Cloning and Sequence Analysis of Hog Cholera Virus(HCV) E2 Gene (돼지 콜레라 바이러스 E2 유전자의 클로닝 및 염기서열분석)

  • 이영기;강신웅;김선원;박성원;이종철;이청호
    • Journal of the Korean Society of Tobacco Science
    • /
    • v.23 no.2
    • /
    • pp.103-108
    • /
    • 2001
  • Hog cholera virus(HCV) was purified from virus infected Bovine kidney cells. From this virus, total protein was analyzed by SDS-PAGE gel electrophoresis and about 55 kDa band of E2 envelope protein was detected. The viral RNA was purified and E2 cDNA was amplified by RT-PCR. E2 cDNA fragment was cloned to PCRII-TOPO cloning vector and named pE2. The analysis of nucleotide sequence showed that this E2 cDNA fragment inserted into pE2 was 1191 nucleotides long and coded 397 amino acids.

  • PDF

유기용매에 의한 CYP2E1의 유도발현 : 단백질형성 효율의 증가에 따른 조절규제기전

  • ;Raymond F. Novak
    • Toxicological Research
    • /
    • v.9 no.2
    • /
    • pp.153-158
    • /
    • 1993
  • Pyridine and acetone are efficacious inducers of CYP2E1 in both rats and rabbits. The response in the elevation of CYP2E1 levels, changes in CYP2E1 mRNA levels, and enhanced translational processing of hepatic CYP2E1 mRNA during the early phase of CYP2E1 induction by the solvents pyridine and acetone were examined. Time-depen-dent incease in CYP2E1 levels occurred at early times (6-24h) following a single dose of pyridine treatmene, as assessed by Western immunoblot analysis, whereas the levels in CYP2E1 mRNA transiently decreased at 12h post-treatment, returning to the level present in untreated animals.

  • PDF

Design of a Logic eFuse OTP Memory IP (Logic eFuse OTP 메모리 IP 설계)

  • Ren, Yongxu;Ha, Pan-bong;Kim, Young-Hee
    • Journal of the Korea Institute of Information and Communication Engineering
    • /
    • v.20 no.2
    • /
    • pp.317-326
    • /
    • 2016
  • In this paper, a logic eFuse (electrical Fuse) OTP (One-Time Programmable) memory IP (Intellectual Property) using only logic transistors to reduce the development cost and period of OTP memory IPs is designed. To secure the reliability of other IPs than the OTP memory IP, a higher voltage of 2,4V than VDD (=1.5V) is supplied to only eFuse links of eFuse OTP memory cells directly through an external pad FSOURCE coming from test equipment in testing wafers. Also, an eFuse OTP memory cell of which power is supplied through FSOURCE and hence the program power is increased in a two-dimensional memory array of 128 rows by 8 columns being also able to make the decoding logic implemented in small area. The layout size of the designed 1kb eFuse OTP memory IP with the Dongbu HiTek's 110nm CIS process is $295.595{\mu}m{\times}455.873{\mu}m$ ($=0.134mm^2$).

Synthesis and Photovoltaic Properties of Low Band Gap π-conjugated Polymers Based on 2-pyran-4-ylidene-malononitrile Derivatives (2-pyran-4-ylidene-malononitrile을 기본으로 하는 작은 Band Gap을 가지는 공중합체의 합성 및 광전변환 특성)

  • You, Hyeri;Shin, Woong;Park, Jeong Bae;Park, Sang Jun;Lim, Jun Heok;Kim, Joo Hyun
    • Applied Chemistry for Engineering
    • /
    • v.20 no.3
    • /
    • pp.273-278
    • /
    • 2009
  • A series of poly[2-(2,6-dimethylpyran-4-ylidene)malononitrile-alt-1,4-bis(dodecyloxy)-2,5-divinylbenzene] (PM-PPV), poly[2-{2,6-Bis-[2-(5-bromothiophen-2-yl)-vinyl]-pyran-4-ylidene}-malononitrile-alt-1,4-bis(dodecyloxy)-2,5-divinylbenzene] (PMT-PPV) and poly[2-[2,6-Bis-(2-{4-[(4-bromophenyl)-phenylamino]-phenyl}-vinyl)-pyran-4-ylidene]-malononitrile-alt-1,4-bis(dodecyloxy)-2,5-divinylbenzene] (PMTPA-PPV) were synthesized by the Heck coupling reaction. The band gap of PM-PPV, PMT-PPV and PMTPA-PPV were 2.18 eV, 1.90 eV and 2.07 eV, respectively. The LUMO energy levels of PM-PPV, PMT-PPV and PMTPA-PPV were 3.65 eV, 3.54 eV and 3.62 eV, respectively and the HOMO energy levels of those were 5.83 eV, 5.61 eV and 5.52 eV, respectively. The photovoltaic devices based on the polymers was fabricated. The efficiency of the solar cells based on PM-PPV, PMT-PPV and PMTPA-PPV were 0.028%, 0.031% and 0.11%, respectively and the open circuit voltage (Voc) was 0.59 V~0.69 V under AM 1.5 G and 1 sun condition ($100mA/cm^2$).

A Study on Promotion Plans of B2B e-Marketplace in Korea (국내 B2B e-marketplace의 활성화방안)

  • Kim, Jong-Deuk;Lee, Sung-Min
    • International Commerce and Information Review
    • /
    • v.5 no.2
    • /
    • pp.91-112
    • /
    • 2003
  • Nowadays, the spreading of electronic commerce using internet demands a lot of change in business environments, as it is called B2B. Especially, the B2B based EC have a majority rates over the 10% of whole EC markets. As the approach way and the core axis of e-Marketplace in B2B markets are changed more by the business section and industry section than by each company sections, all of the world leading company including Korea are trying to take a prior occupation in e-Marketplace market. In korea, B2B e-Marketplace are mainly leaded by ministry of commerce, industry and energy which choice the company, run a trial managed company. Above MOCIE efforts are now having a lot of trial and error. Accordingly, this thesis are focused on researching the construction trends of B2B e-Marketplace, the future prospects, and promotion plans.

  • PDF

Effects of Selenium and Vitamin E Administration on the Semen Characteristics, Blood Chemical Values and Hormone in Hanwoo Sires II. Changes of Selenium and Vitamin E Concentrations of Blood in Hanwoo Sires after Selenium, Vitamin E and rBST Administration (Selenium 과 Vitamin E 투여가 한우 종모우의 정액성상, 혈액성분 및 호르몬 변화에 미치는 효과 II. Selenium, Vitamin E 및 rBST 투여가 한우 종모우의 혈중내 Selenium 과 Vitamin E 의 농도 변화에 미치는 효과)

  • 박동헌;양부근;김종복;전기준;정희태;박춘근;이성수;박노형;원유석
    • Korean Journal of Animal Reproduction
    • /
    • v.23 no.3
    • /
    • pp.205-212
    • /
    • 1999
  • The present study was designed to examine the effects of selenium(Se), vitamin E(Vit. E) and recombinant Bovine Somatotropin(rBST) administration on the selenium and vitamin E concentrations of blood in Hanwoo sires Hanwoo sires were randomly assigned to five groups; 1. control, 2. rBST, 0.09mg/kg body weight (BW) 3. Vit E, 1,500IU/kg BW, 4. Se 0.lmg/kg BW, 5. Vit E, 1.500IU plus Se 0.1mg/kg BW. rBST, Vit. E and Se for each experimental group were given 6 times at 15 days interval by intramuscular injection. Blood samples were collected 10 times for experimental periods, separated the serum by centrifugation, and stored at -7$0^{\circ}C$. Se and Vito E concentrations in blood were measured by fluorophotometer and HPLC. Se concentrations of blood in control, rBST, Vito E, Se and Se plus Vito E groups were 64.55, 65.50, 68.15, 73.11 and 74.09 ppb/$m\ell$, respectively. Se concentration in Vit. E plus Se group was significantly higher than in control and rBST groups (P<0.05), but Vito E group was not significantly different in control and rBST groups(P>0.05). The Vit. E concentrations of blood in control, rBST, Vit. E, Se and Se plus Vit. E groups were 2.27, 2.32, 2.80, 2.58 and 2.75 ppm/$m\ell$, respectively. Vit. E and Vit. E plus Se groups were slightly higher than those of any other groups, but not significantly difference in 외 I experimental groups(P<0.05). These results indicate that Se and Vit. E concentrations of blood were slightly increased with the injection of Se and Vit. E in Hanwoo sires.

  • PDF