• 제목/요약/키워드: Dynamic association

검색결과 2,053건 처리시간 0.03초

Actin Engine in Immunological Synapse

  • Piragyte, Indre;Jun, Chang-Duk
    • IMMUNE NETWORK
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    • 제12권3호
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    • pp.71-83
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    • 2012
  • T cell activation and function require physical contact with antigen presenting cells at a specialized junctional structure known as the immunological synapse. Once formed, the immunological synapse leads to sustained T cell receptor-mediated signalling and stabilized adhesion. High resolution microscopy indeed had a great impact in understanding the function and dynamic structure of immunological synapse. Trends of recent research are now moving towards understanding the mechanical part of immune system, expanding our knowledge in mechanosensitivity, force generation, and biophysics of cell-cell interaction. Actin cytoskeleton plays inevitable role in adaptive immune system, allowing it to bear dynamic and precise characteristics at the same time. The regulation of mechanical engine seems very complicated and overlapping, but it enables cells to be very sensitive to external signals such as surface rigidity. In this review, we focus on actin regulators and how immune cells regulate dynamic actin rearrangement process to drive the formation of immunological synapse.

Impact of gate protection silicon nitride film on the sub-quarter micron transistor performances in dynamic random access memory devices

  • Choy, J.-H.
    • 한국결정성장학회지
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    • 제14권2호
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    • pp.47-49
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    • 2004
  • Gate protection $SiN_x$ as an alternative to a conventional re-oxidation process in Dynamic Random Access Memory devices is investigated. This process can not only protect the gate electrode tungsten against oxidation, but also save the thermal budget due to the re-oxidation. The protection $SiN_x$ process is applied to the poly-Si gate, and its device performance is measured and compared with the re-oxidation processed poly-Si gate. The results on the gate dielectric integrity show that etch damage-curing capability of protection $SiN_x$ is comparable to the re-oxidation process. In addition, the hot carrier immunity of the $SiN_x$ deposited gate is superior to that of re-oxidation processed gate.

지진하중을 받는 대공간 구조물의 동적 거동 특성에 관한 연구 (A Study on the Characteristics of dynamic Behaviors for the Spatial Structures under Seismic Load)

  • 김민식;이상주;이동우;한상을
    • 한국공간구조학회:학술대회논문집
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    • 한국공간구조학회 2005년도 춘계학술발표회 및 정기총회 2권1호(통권2호)
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    • pp.227-235
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    • 2005
  • The earthquake-resistant structural systems have to ensure the sufficient stiffness and ductility for the stability. For those purposes, recently, the performance design concept to increase the degree of absorbed energy level of structures has been proposed. One practical way of the performance design in the spatial structures is to apply the isolation system to boundary parts of roof system and sub-structure to obtain the target performance. So, it is necessary to examine the characteristics of dynamic behavior of spatial structures governed by higher modes rather than lower modes different from the cases of high rise buildings. The objectives of this paper are to develop the equivalent model to simplify the analytical processes and to investigate the dynamic behavior of roof system according to the mass and the stiffness of sub-structures as a fundamental study of performance design for the spatial structures.

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탄성 현수선 요소를 이용한 케이블 구조물의 비선형 동적해석 (Non-linear Dynamic Analysis of Cable Structures Using Elastic Catenary)

  • 황진홍;이상주;한상을
    • 한국공간구조학회:학술대회논문집
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    • 한국공간구조학회 2005년도 춘계학술발표회 및 정기총회 2권1호(통권2호)
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    • pp.167-172
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    • 2005
  • In the dynamic analysis of cable structures, geometrical non-linearity due to the flexibility of cables must be considered efficiently. In this paper, formulation of tangent stiffness matrix of elastic catenary cable is derived by using relative nodal displacements, self-weight and unstressed cable length. Free vibration analysis of simply supported cable using elastic catenary cable elements is conducted and compared with that using truss elements. The result shows that elastic catenary cable elements are more compatible than truss elements in the case of analysis of cable structures. Furthermore, the characteristic of dynamic behaviors of cable structures by temporary unstability phenomenon is confirmed.

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투시조영검사에서 동영상의 컴퓨터 동시캡쳐방식과 적응 예 (Syncronous Computer-Capturing Method of Dynamic Images on Fluoroscopic Studies and Applications)

  • 장동혁;이경록;장지원;김대중;서정환;박영순
    • 대한방사선협회지
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    • 제29권1호
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    • pp.25-30
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    • 2003
  • Purpose : The purpose of this study is to present computer-capturing method of dynamic images on fluoroscopic studies, as a substitution for video-recording method, and to help the quantitative analysis of the dynamic studies. Materials and Methods: Compu

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스캐폴딩 집단유형 및 능력수준에 따른 역동적 평가과정이 유아의 측정능력에 미치는 영향 (The Effects of Dynamic Assessment in Terms of Scaffolding Group Types and Young Children's Measurement Ability Levels)

  • 고은미;남미경;황해익
    • 아동학회지
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    • 제30권5호
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    • pp.225-243
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    • 2009
  • This study analyzed the effects of dynamic assessment in terms of scaffolding group types and young children's measurement ability levels. Participants were five-year-old children in Busan divided into 2 experimental groups and control groups. The Assessment Tools for Young Children's Measurement Ability (Ko & Hwang, 2008) consisted of 4 sub tests for ‘length', 'width', and 'weight' concepts. Data were analyzed by t-test and ANOVA. Results showed significant differences between experimental and control groups in post-test scores, but no significant differences between individual and peer collaboration groups in amount of scaffolding. Significant improvements showed in all of the measurement ability level groups : individual higher, individual lower, peer collaboration higher and peer collaboration lower level scaffolding groups.

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쌀 섭취경로에서 동적모델을 사용한 장반감기핵종의 거동해석 및 내부피폭 선량계산 (Nuclides Transport Analysis and Dose Calculation Using Dynamic Model for Rice Ingestion Pathway)

  • 이창우;최용호;황원태;이정호
    • Journal of Radiation Protection and Research
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    • 제17권2호
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    • pp.15-23
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    • 1992
  • 논-쌀-사람 경로에서 동적모델을 이용하여 Cs-137과 Sr-90의 거동을 분석하고 쌀 섭취에 의한 내부피폭 선량을 계산하였다. 토양 흡착력이 큰 Cs-137이 더 오랫동안 논 토양에 잔류하였다. 벼 성장기간 중에 침적이 있을 때는 엽면침적경로에 의한 오염이 지배적이었다.

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Winning Back Attendance: Effects of Winning Performance, Online Search, and the MLB Rule Changes for More Dynamic Games

  • Rhino Kim;Sue Ryung Chang
    • Asia Marketing Journal
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    • 제25권3호
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    • pp.148-159
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    • 2023
  • As Major League Baseball (MLB)'s continuous decline in popularity has caused its game attendance to drop gradually, the league makes a desperate attempt such as game rule changes to remain relevant. Along with the introduction of new rules to make games more dynamic such as the pitch clock, bigger bases, and defensive shift limitations, it is important for MLB franchises to understand drivers for game attendance. We focus on the effect of accumulated winning performance of the two teams on game attendance, one of the key drivers of game attendance, and investigate how it is influenced by consumer and industry factors such as online search and game rule changes. We find that game attendance increases as the prior winning performance of the home (away) team increases (decreases). We also find that online search and rule changes for more dynamic games moderate the effect of winning performance on game attendance.

Uncovering the Role of External APIs in Driving Dynamic Ecosystem Growth

  • Um, Sungyong;Kang, Martin;Son, Insoo
    • 한국정보시스템학회지:정보시스템연구
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    • 제33권2호
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    • pp.143-168
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    • 2024
  • Purpose This study highlights the crucial role of external APIs in driving dynamic evolution within a digital ecosystem. Drawing on the concept of evolutionary network biology perspective, this study hypothesizes that APIs' (non)network properties can significantly impact a digital ecosystem's product variety. Design/methodology/approach This study analyzes plug-in source code data from WordPress.org between January 2004 and December 2014, using survival analysis to test this hypothesis. Findings The empirical results demonstrate that external APIs have a more significant impact on promoting ecosystem evolution over time than those offered by a focal platform system. This research enhances our understanding of ecosystem dynamics and emphasizes the critical role of the generative nature of APIs in fostering ecosystem growth.

Development of a Dynamic Downscaling Method for Use in Short-Range Atmospheric Dispersion Modeling Near Nuclear Power Plants

  • Sang-Hyun Lee;Su-Bin Oh;Chun-Ji Kim;Chun-Sil Jin;Hyun-Ha Lee
    • Journal of Radiation Protection and Research
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    • 제48권1호
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    • pp.28-43
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    • 2023
  • Background: High-fidelity meteorological data is a prerequisite for the realistic simulation of atmospheric dispersion of radioactive materials near nuclear power plants (NPPs). However, many meteorological models frequently overestimate near-surface wind speeds, failing to represent local meteorological conditions near NPPs. This study presents a new high-resolution (approximately 1 km) meteorological downscaling method for modeling short-range (< 100 km) atmospheric dispersion of accidental NPP plumes. Materials and Methods: Six considerations from literature reviews have been suggested for a new dynamic downscaling method. The dynamic downscaling method is developed based on the Weather Research and Forecasting (WRF) model version 3.6.1, applying high-resolution land-use and topography data. In addition, a new subgrid-scale topographic drag parameterization has been implemented for a realistic representation of the atmospheric surface-layer momentum transfer. Finally, a year-long simulation for the Kori and Wolsong NPPs, located in southeastern coastal areas, has been made for 2016 and evaluated against operational surface meteorological measurements and the NPPs' on-site weather stations. Results and Discussion: The new dynamic downscaling method can represent multiscale atmospheric motions from the synoptic to the boundary-layer scales and produce three-dimensional local meteorological fields near the NPPs with a 1.2 km grid resolution. Comparing the year-long simulation against the measurements showed a salient improvement in simulating near-surface wind fields by reducing the root mean square error of approximately 1 m/s. Furthermore, the improved wind field simulation led to a better agreement in the Eulerian estimate of the local atmospheric dispersion. The new subgrid-scale topographic drag parameterization was essential for improved performance, suggesting the importance of the subgrid-scale momentum interactions in the atmospheric surface layer. Conclusion: A new dynamic downscaling method has been developed to produce high-resolution local meteorological fields around the Kori and Wolsong NPPs, which can be used in short-range atmospheric dispersion modeling near the NPPs.