• 제목/요약/키워드: Double regulating

검색결과 63건 처리시간 0.023초

Aspergillus nidulans에서 유성분화 능동조절 유전자 nsdD와 veA 또는 nsdC의 이중결실돌연변이의 분리 및 분석 (Isolation and Characterization of Double Deletion Mutants of nsdD and veA or nsdC, the Genes Positive Regulating Sexual Development of Aspergillus nidulans)

  • 김이한;김하은;한동민
    • 미생물학회지
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    • 제49권4호
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    • pp.419-423
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    • 2013
  • Aspergillus nidulans에는 유성분화를 능동조절하는 nsdD, nsdC 그리고 veA의 3 유전자가 알려져 있다. 이들 유전자의 돌연변이들은 각각을 서로 교배한 이핵체에 cleistothecia를 형성하지 못하기 때문에 이중돌연변이의 분리가 어려웠다. 본 연구에서는 ${\Delta}nsdD$ 돌연변이가 저산소 및 저온조건에서 성숙한 cleistothecia를 형성하는 것을 이용하여 ${\Delta}nsdD$${\Delta}veA$${\Delta}nsdD$${\Delta}nsdC$의 이중돌연변이를 분리하였다. 이중돌연변이의 형질을 분석한 결과 nsdD 유전자는 veA 또는 nsdC와 독립적으로 정단성장에 관여하는 것으로 보였다. 색소생성형질은 veA나 nsdC가 nsdD에 대해 상위에 있는 것으로 나타났으며, lactose가 탄소원인 액체배지에서 무성포자를 생성하는 형질이 이중돌연변이에도 보임에 따라 이 형질은 nsdC의 고유한 특성으로 사료된다.

러너와 가이드 베인의 연동을 통한 마이크로 카프란 수차의 출력 최적화 (Output Optimization of Microhydro Kaplan Turbine by Double Regulating Runner and Guide Vane)

  • 박노현;이영우
    • 한국유체기계학회 논문집
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    • 제16권1호
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    • pp.17-23
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    • 2013
  • Recently so much attention has been focused on renewable energy and, since its sources to exploit are already almost saturated in the country, the practical alternative to this situation could be a micro-turbine which uses the low head and low flow. From a point of view of local micro-turbine design capacity and manufacturing technology, the problems such as the accumulation of technical skills, the expansion of related industries, the national policy expansion and the turbine efficiency to improve are still vulnerable and it's true that there are also negative views about the economic feasibility, the technicity and the operation management of the micro-turbine. However, if the improvement can be done in technology of low-head double regulation micro-turbine to generate more outputs and the operation management can be reliably realized, the micro-turbine will be re-evaluated as an appliable source of renewable energy, even the output is small, and by a paradigm shift, it could realize a power generation as an economic and rational system.

전기 이중층의 상호작용을 고려한 2차원 슬릿 내의 전기삼투 유동에 관한 이론적 해석 (An Theoretical Analysis of Electro-osmotic Flow in 2-dimensional slit with Electrical Double Layers in Interaction)

  • 이대근
    • 유체기계공업학회:학술대회논문집
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    • 유체기계공업학회 2006년 제4회 한국유체공학학술대회 논문집
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    • pp.497-500
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    • 2006
  • An theoretical analysis on the electro-osmotic flow in a 2-dimensional slit, that is induced by an external electric field acting on the electrical double layers near the slit wall, was performed. Especially, although there were many studies on the interacting electrical double layers, it was found in this study that they have several physical or mathematical fallacies. To resolve these, the general solution on the charge-regulating slit with the height as a parameter was obtained. The results of this work can provide the electrokinetic solution of nanoscale slit with the electrical double layer interaction as well as that of microscale slit without the interaction and can be used as the benchmark of a numerical analysis and the reference of electrokinetic flow path design.

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병렬식 하이브리드 흡수식 냉온수기 동특성 시뮬레이션 연구 (A Study on Dynamic Simulation of a Hybrid Parallel Absorption Chiller)

  • 신영기;서정아;우성민;김효상
    • 대한설비공학회:학술대회논문집
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    • 대한설비공학회 2008년도 동계학술발표대회 논문집
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    • pp.630-635
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    • 2008
  • A dynamic model has been developed to investigate the operability of a single and double-effect solar energy assisted parallel type absorption chiller. In the study, main components and fluid transport mechanism have been modeled. Flow discharge coefficients of the valves and the pumps were optimized for the double-effect mode with solar-heated water circulated. The model was run for the single mode with solar energy supply only and the solar/gas driving double effect mode. And the cases of the double mode with and without the solar energy were compared. From the simulation results, it was found that the present configuration of the chiller is not capable of regulating solution flow rates according to variable solar energy input. And the single mode utilizing the solar energy only is not practical. It is suggested to operate the system in the double mode and the flow rate control system adaptive to variable solar energy input has to be developed.

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표면처리를 이용한 단일진공관과 기존 이중진공관 태양열집열기의 성능비교 연구 (Study on Performance Comparison for Solar Collectors with Single Evacuated Tube using Surface Treatment and Commercial Double Evacuated Tube)

  • 전태규;양영준;이경희;안영철
    • 한국기계가공학회지
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    • 제12권5호
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    • pp.149-156
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    • 2013
  • The performances of solar collectors with single and double evacuated tube were experimentally compared. The solar collector with single evacuated tube using surface treatment in this study consists of radiation fin, heat pipe, absorber plate, glass tube, cap and regulating valve, and so on. Surface treatment was conducted for heat pipe and absorber plate with black chrome plating and copper black coating. As the results, the performance of solar collector with single evacuated tube using surface treatment showed good results compared that of double evacuated tube. Absorber plate played a positive role in performance and showed increase of about 28%. Further performance depends on vacuum degree and vacuum degree has to be considered economical efficiency in solar collector.

Hybrid Plasma Processing에 의한 Si3N4-SiC계 미립자의 합성과정 제어 (Process Control for the Synthesis of Ultrafine Si3N4-SiC Powders by the Hybrid Plasma Processing)

  • 이형직
    • 한국세라믹학회지
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    • 제29권9호
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    • pp.681-688
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    • 1992
  • Ultrafine Si3N4 and Si3N4+SiC mixed powders were synthesized through thermal plasma chemical vapor deposition(CVD) using a hybrid plasma, which was characterized by the supersposition of a radio-frequency plasma and arc jet. The reactant SiCl4 was injected into an arc jet and completely decomposed in a hybrid plasma, and the second reactant CH4 and/or NH3 mixed with H2 were injected into the tail flame through double stage ring slits. In the case of ultrafine Si3N4 powder synthesis, reaction efficiency increased significantly by double stage injection compared to single stage one, although crystallizing behaviors depended upon injection speed of reactive quenching gas (NH3+N2) and injection method. For the preparation of Si2N4+SiC mixed powders, N/C composition ratio could be controlled by regulating the injection speed of NH3 and/or CH4 reactant and H2 quenching gas mixtures as well as by adjusting the reaction space.

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중국의 상표사용허가계약의 중첩체결에 관한 연구 (A Study on the Matter of Double Contract for Trademark License in China)

  • 송수련
    • 무역상무연구
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    • 제73권
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    • pp.1-20
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    • 2017
  • There are many safeguards and measures available regulating the protection of a trademark and its registered holder, however, the protection of a licensee in a trademark license agreement is also important for protection of a intellectual property. Therefore, there are several measures in place for the protection of licensees' interests in Chinese trademark law. Article 43(3) of the Chinese Trademark Law rules a licensor who licenses others to use his registered trademark shall submit the trademark licensing to the trademark office for file, and the trademark office shall announce the trademark licensing to public. Without filing, the trademark licensing shall not be used against a bona fide third party. It means a licensee can not use an unrecorded license with the relevant trademark authority against third parties - essentially, this means that a licensee should insist on having their trademark license agreements recorded against the relevant trademark authority, so that a licensee's interests are protected as against the assignees, licensees and other types of third parties. Otherwise a third party in good faith can use the registered trademark legally against a licensee even though a trademark license agreement between a licensor and licensee is still valid.

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태양열을 이용한 일이중 겸용 흡수식 냉온수기 동적성능 모사연구 (A Study of Dynamic Simulation of a Hybrid Absorption Chiller Utilizing Solar Power)

  • 신영기;서정아;우성민;김효상
    • 대한설비공학회:학술대회논문집
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    • 대한설비공학회 2009년도 하계학술발표대회 논문집
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    • pp.967-972
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    • 2009
  • A dynamic model has been developed to investigate the operability of a single and double-effect solar energy assisted parallel type absorption chiller. In the study, main components and fluid transport mechanism were modeled. And solar radiation and the solar collector also were also modeled along with its control design. The model was run for the single mode with solar energy supply only and the solar/gas driving double effect mode. From the simulation results, it was found that the present configuration of the chiller is not capable of regulating solution flow rates according to variable solar energy input. And the issues of the excessive circulation flowrate and the mismatch between available solar power and cooling load discourages the use of the single mode, but the dual use of gas and solar power is recommendable in view of controllability and enhanced COP.

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태양열 보조열원을 이용한 흡수식 시스템의 동적 시뮬레이션에 의한 과도운전 특성 평가 (Dynamic Simulation of Transient Operations of a Solar Power-Assisted Absorption Chiller)

  • 신영기;서정아;우성민
    • 설비공학논문집
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    • 제22권2호
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    • pp.78-85
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    • 2010
  • A dynamic model has been developed to investigate the operability of a single and double-effect solar energy assisted parallel type absorption chiller. In the study, main components and fluid transport mechanism were modeled. And solar radiation and the solar collector were also modeled along with its control design. The model was run for the single mode with solar energy supply only and the solar/gas driving double effect mode. From the simulation results, it was found that the present configuration of the chiller is not capable of regulating solution flow rates according to variable solar energy input. And the issues of the excessive circulation flow rate and the mismatch between available solar power and cooling load discourages the use of the single mode, but the dual use of gas and solar power is recommendable in view of controllability and enhanced COP.

SET7-mediated TIP60 methylation is essential for DNA double-strand break repair

  • Song Hyun, Kim;Junyoung, Park;Jin Woo, Park;Ja Young, Hahm;Seobin, Yoon;In Jun, Hwang;Keun Pil, Kim;Sang-Beom, Seo
    • BMB Reports
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    • 제55권11호
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    • pp.541-546
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    • 2022
  • The repair of DNA double-strand breaks (DSBs) by homologous recombination (HR) is crucial for maintaining genomic integrity and is involved in numerous fundamental biological processes. Post-translational modifications by proteins play an important role in regulating DNA repair. Here, we report that the methyltransferase SET7 regulates HR-mediated DSB repair by methylating TIP60, a histone acetyltransferase and tumor suppressor involved in gene expression and protein stability. We show that SET7 targets TIP60 for methylation at K137, which facilitates DSB repair by promoting HR and determines cell viability against DNA damage. Interestingly, TIP60 demethylation is catalyzed by LSD1, which affects HR efficiency. Taken together, our findings reveal the importance of TIP60 methylation status by SET7 and LSD1 in the DSB repair pathway.