• 제목/요약/키워드: Double regulating

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Isolation and Characterization of Double Deletion Mutants of nsdD and veA or nsdC, the Genes Positive Regulating Sexual Development of Aspergillus nidulans (Aspergillus nidulans에서 유성분화 능동조절 유전자 nsdD와 veA 또는 nsdC의 이중결실돌연변이의 분리 및 분석)

  • Kim, Lee-Han;Kim, Ha-Eun;Han, Dong-Min
    • Korean Journal of Microbiology
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    • v.49 no.4
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    • pp.419-423
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    • 2013
  • Three genes, nsdD, nsdC, and veA are known to be necessary for positive regulating sexual development of Aspergillus nidulans. Since the mutants of those genes hardly form fruiting bodies in heterokaryons constructed by cross between two of them, it is difficult to isolate double mutants. In this work, double mutants of ${\Delta}nsdD$ ${\Delta}veA$ and ${\Delta}nsdD$ ${\Delta}nsdC$ were isolated using the characteristic of the nsdD deletion mutant that it could develop mature cleistothecia in hypoxic and low temperature culture condition. According to the phenotypes of double mutants, the nsdD gene controls the apical growth independently with veA or nsdC. Deletion of veA or nsdC was epistatic to nsdD deletion for pigment production. Conidia formation in submerged culture with lactose as sole carbon source was observed in ${\Delta}nsdD$ ${\Delta}nsdC$ double mutant implicating it to be unique phenotype of nsdC deletion.

Output Optimization of Microhydro Kaplan Turbine by Double Regulating Runner and Guide Vane (러너와 가이드 베인의 연동을 통한 마이크로 카프란 수차의 출력 최적화)

  • Park, No-Hyun;Rhee, Young-Woo
    • The KSFM Journal of Fluid Machinery
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    • v.16 no.1
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    • pp.17-23
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    • 2013
  • Recently so much attention has been focused on renewable energy and, since its sources to exploit are already almost saturated in the country, the practical alternative to this situation could be a micro-turbine which uses the low head and low flow. From a point of view of local micro-turbine design capacity and manufacturing technology, the problems such as the accumulation of technical skills, the expansion of related industries, the national policy expansion and the turbine efficiency to improve are still vulnerable and it's true that there are also negative views about the economic feasibility, the technicity and the operation management of the micro-turbine. However, if the improvement can be done in technology of low-head double regulation micro-turbine to generate more outputs and the operation management can be reliably realized, the micro-turbine will be re-evaluated as an appliable source of renewable energy, even the output is small, and by a paradigm shift, it could realize a power generation as an economic and rational system.

An Theoretical Analysis of Electro-osmotic Flow in 2-dimensional slit with Electrical Double Layers in Interaction (전기 이중층의 상호작용을 고려한 2차원 슬릿 내의 전기삼투 유동에 관한 이론적 해석)

  • Lee, Dae-Keun
    • 유체기계공업학회:학술대회논문집
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    • 2006.08a
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    • pp.497-500
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    • 2006
  • An theoretical analysis on the electro-osmotic flow in a 2-dimensional slit, that is induced by an external electric field acting on the electrical double layers near the slit wall, was performed. Especially, although there were many studies on the interacting electrical double layers, it was found in this study that they have several physical or mathematical fallacies. To resolve these, the general solution on the charge-regulating slit with the height as a parameter was obtained. The results of this work can provide the electrokinetic solution of nanoscale slit with the electrical double layer interaction as well as that of microscale slit without the interaction and can be used as the benchmark of a numerical analysis and the reference of electrokinetic flow path design.

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A Study on Dynamic Simulation of a Hybrid Parallel Absorption Chiller (병렬식 하이브리드 흡수식 냉온수기 동특성 시뮬레이션 연구)

  • Shin, Young-Gy;Seo, Jung-A;Woo, Sung-Min;Kim, Hyo-Sang
    • Proceedings of the SAREK Conference
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    • 2008.11a
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    • pp.630-635
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    • 2008
  • A dynamic model has been developed to investigate the operability of a single and double-effect solar energy assisted parallel type absorption chiller. In the study, main components and fluid transport mechanism have been modeled. Flow discharge coefficients of the valves and the pumps were optimized for the double-effect mode with solar-heated water circulated. The model was run for the single mode with solar energy supply only and the solar/gas driving double effect mode. And the cases of the double mode with and without the solar energy were compared. From the simulation results, it was found that the present configuration of the chiller is not capable of regulating solution flow rates according to variable solar energy input. And the single mode utilizing the solar energy only is not practical. It is suggested to operate the system in the double mode and the flow rate control system adaptive to variable solar energy input has to be developed.

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Study on Performance Comparison for Solar Collectors with Single Evacuated Tube using Surface Treatment and Commercial Double Evacuated Tube (표면처리를 이용한 단일진공관과 기존 이중진공관 태양열집열기의 성능비교 연구)

  • Chun, Tae-Kyu;Yang, Young-Joon;Lee, Kyung-Hee;Ahn, Young-Chull
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.12 no.5
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    • pp.149-156
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    • 2013
  • The performances of solar collectors with single and double evacuated tube were experimentally compared. The solar collector with single evacuated tube using surface treatment in this study consists of radiation fin, heat pipe, absorber plate, glass tube, cap and regulating valve, and so on. Surface treatment was conducted for heat pipe and absorber plate with black chrome plating and copper black coating. As the results, the performance of solar collector with single evacuated tube using surface treatment showed good results compared that of double evacuated tube. Absorber plate played a positive role in performance and showed increase of about 28%. Further performance depends on vacuum degree and vacuum degree has to be considered economical efficiency in solar collector.

Process Control for the Synthesis of Ultrafine Si3N4-SiC Powders by the Hybrid Plasma Processing (Hybrid Plasma Processing에 의한 Si3N4-SiC계 미립자의 합성과정 제어)

  • ;吉田禮
    • Journal of the Korean Ceramic Society
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    • v.29 no.9
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    • pp.681-688
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    • 1992
  • Ultrafine Si3N4 and Si3N4+SiC mixed powders were synthesized through thermal plasma chemical vapor deposition(CVD) using a hybrid plasma, which was characterized by the supersposition of a radio-frequency plasma and arc jet. The reactant SiCl4 was injected into an arc jet and completely decomposed in a hybrid plasma, and the second reactant CH4 and/or NH3 mixed with H2 were injected into the tail flame through double stage ring slits. In the case of ultrafine Si3N4 powder synthesis, reaction efficiency increased significantly by double stage injection compared to single stage one, although crystallizing behaviors depended upon injection speed of reactive quenching gas (NH3+N2) and injection method. For the preparation of Si2N4+SiC mixed powders, N/C composition ratio could be controlled by regulating the injection speed of NH3 and/or CH4 reactant and H2 quenching gas mixtures as well as by adjusting the reaction space.

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A Study on the Matter of Double Contract for Trademark License in China (중국의 상표사용허가계약의 중첩체결에 관한 연구)

  • SONG, Soo-Ryun
    • THE INTERNATIONAL COMMERCE & LAW REVIEW
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    • v.73
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    • pp.1-20
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    • 2017
  • There are many safeguards and measures available regulating the protection of a trademark and its registered holder, however, the protection of a licensee in a trademark license agreement is also important for protection of a intellectual property. Therefore, there are several measures in place for the protection of licensees' interests in Chinese trademark law. Article 43(3) of the Chinese Trademark Law rules a licensor who licenses others to use his registered trademark shall submit the trademark licensing to the trademark office for file, and the trademark office shall announce the trademark licensing to public. Without filing, the trademark licensing shall not be used against a bona fide third party. It means a licensee can not use an unrecorded license with the relevant trademark authority against third parties - essentially, this means that a licensee should insist on having their trademark license agreements recorded against the relevant trademark authority, so that a licensee's interests are protected as against the assignees, licensees and other types of third parties. Otherwise a third party in good faith can use the registered trademark legally against a licensee even though a trademark license agreement between a licensor and licensee is still valid.

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A Study of Dynamic Simulation of a Hybrid Absorption Chiller Utilizing Solar Power (태양열을 이용한 일이중 겸용 흡수식 냉온수기 동적성능 모사연구)

  • Shin, Young-Gy;Seo, Jung-A;Woo, Sung-Min;Kim, Hyo-Sang
    • Proceedings of the SAREK Conference
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    • 2009.06a
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    • pp.967-972
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    • 2009
  • A dynamic model has been developed to investigate the operability of a single and double-effect solar energy assisted parallel type absorption chiller. In the study, main components and fluid transport mechanism were modeled. And solar radiation and the solar collector also were also modeled along with its control design. The model was run for the single mode with solar energy supply only and the solar/gas driving double effect mode. From the simulation results, it was found that the present configuration of the chiller is not capable of regulating solution flow rates according to variable solar energy input. And the issues of the excessive circulation flowrate and the mismatch between available solar power and cooling load discourages the use of the single mode, but the dual use of gas and solar power is recommendable in view of controllability and enhanced COP.

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Dynamic Simulation of Transient Operations of a Solar Power-Assisted Absorption Chiller (태양열 보조열원을 이용한 흡수식 시스템의 동적 시뮬레이션에 의한 과도운전 특성 평가)

  • Shin, Young-Gy;Seo, Jung-A;Woo, Sung-Min
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.22 no.2
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    • pp.78-85
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    • 2010
  • A dynamic model has been developed to investigate the operability of a single and double-effect solar energy assisted parallel type absorption chiller. In the study, main components and fluid transport mechanism were modeled. And solar radiation and the solar collector were also modeled along with its control design. The model was run for the single mode with solar energy supply only and the solar/gas driving double effect mode. From the simulation results, it was found that the present configuration of the chiller is not capable of regulating solution flow rates according to variable solar energy input. And the issues of the excessive circulation flow rate and the mismatch between available solar power and cooling load discourages the use of the single mode, but the dual use of gas and solar power is recommendable in view of controllability and enhanced COP.

SET7-mediated TIP60 methylation is essential for DNA double-strand break repair

  • Song Hyun, Kim;Junyoung, Park;Jin Woo, Park;Ja Young, Hahm;Seobin, Yoon;In Jun, Hwang;Keun Pil, Kim;Sang-Beom, Seo
    • BMB Reports
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    • v.55 no.11
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    • pp.541-546
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    • 2022
  • The repair of DNA double-strand breaks (DSBs) by homologous recombination (HR) is crucial for maintaining genomic integrity and is involved in numerous fundamental biological processes. Post-translational modifications by proteins play an important role in regulating DNA repair. Here, we report that the methyltransferase SET7 regulates HR-mediated DSB repair by methylating TIP60, a histone acetyltransferase and tumor suppressor involved in gene expression and protein stability. We show that SET7 targets TIP60 for methylation at K137, which facilitates DSB repair by promoting HR and determines cell viability against DNA damage. Interestingly, TIP60 demethylation is catalyzed by LSD1, which affects HR efficiency. Taken together, our findings reveal the importance of TIP60 methylation status by SET7 and LSD1 in the DSB repair pathway.