• Journal of Korean Neurosurgical Society
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• v.63 no.4
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• pp.519-531
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• 2020

Objective : The purpose of this study is identify the operation status of the neurosurgical care units (NCUs) in neurosurgical residency training hospitals nationwide and determine needed changes by comparing findings with those obtained from the Korean Neurosurgical Society (KNS) and Korean Society of Neurointensive Care Medicine (KNIC) survey of 2010. Method : This survey was conducted over 1 year in 86 neurosurgical residency training hospitals and two neurosurgery specialist hospitals and focused on the following areas : 1) the current status of the infrastructure and operating systems of NCUs in Korea, 2) barriers to installing neurointensivist team systems, 3) future roles of the KNS and KNIC, and 4) a handbook for physicians and practitioners in NCUs. We compared and analyzed the results of this survey with those from a KNIC survey of 2010. Results : Seventy seven hospitals (87.5%) participated in the survey. Nineteen hospitals (24.7%) employed a neurointensivist or faculty member; Thirty seven hospitals (48.1%) reported high demand for neurointensivists, and 62 hospitals (80.5%) stated that the mandatory deployment of a neurointensivist improved the quality of patient care. Forty four hospitals (57.1%) believed that hiring neurointensivist would increase hospital costs, and in response to a question on potential earnings declines. In terms of potential solutions to these problems, 70 respondents (90.9%) maintained that additional fees were necessary for neurointensivists' work, and 64 (83.1%) answered that direct support was needed of the personnel expenses for neurointensivists. Conclusion : We hope the results of this survey will guide successful implementation of neurointensivist systems across Korea.

• Journal of the Korean Society of Food Science and Nutrition
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• v.37 no.11
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• pp.1497-1506
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• 2008

In relation to making tofu with red ginseng extract, the effects of added red ginseng extract on the storage and antioxidant activity of tofu were investigated. When red ginseng extract was added in $0.5%{\sim}2%$ of dried soybean, differences in texture, color and sensory properties were compared. The textural properties of tofu slightly increased depending on the added amount of red ginseng extract in terms of the hardness and springiness: significant difference was demonstrated in the tofu with 2% red ginseng extract, and the color properties also significantly increased in terms of the values of L, a, and b. As a result of sensory evaluation, although the preference to color tended to diminish, as the peculiar taste of red ginseng was significantly perceived, the overall preference did not show any statistical difference. Therefore, the addition of red ginseng extract may be interpreted as not having negative effect on the preference of consumers. There was no change at the early stage of storage in pH, turbidity and total microbial count when the tofu was stored at $15^{\circ}C$. However, the changes in pH and in turbidity, and total microbial counts according to the addition of red ginseng extract took place from the second day and from the sixth day of storage, respectively, suggesting that the shelf-life of tofu may be extended due to its antimicrobial effect. Especially, the highest antimicrobial effect was observed tofu with 2% red ginseng extract. Concerning the antioxidant activity of tofu using oxygen radical absorbance capacity (ORAC) assay, the antioxidant activity significantly increased along with the increase in concentration of red ginseng extract. In ORACOH.assay, the pro-oxidant activity was shown in the tofu added with red ginseng extract.

• Journal of Korea Multimedia Society
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• v.9 no.11
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• pp.1421-1434
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• 2006

Spatial data warehouses provide analytical information for decision supports using SOLAP (Spatial On-Line Analytical Processing) operations. Many researches have been studied to reduce analysis cost of SOLAP operations using pre-aggregation methods. These methods use the index composed of fixed size nodes for supporting the concept hierarchy. Therefore, these methods have many unused entries in sparse data area. Also, it is impossible to support the concept hierarchy in dense data area. In this paper, we propose a dynamic pre-aggregation index method based on the spatial hierarchy. The proposed method uses the level of the index for supporting the concept hierarchy. In sparse data area, if sibling nodes have a few used entries, those entries are integrated in a node and the parent entries share the node. In dense data area, if a node has many objects, the node is connected with linked list of several nodes and data is stored in linked nodes. Therefore, the proposed method saves the space of unused entries by integrating nodes. Moreover it can support the concept hierarchy because a node is not divided by linked nodes. Experimental result shows that the proposed method saves both space and aggregation search cost with the similar building cost of other methods.

• Journal of Navigation and Port Research
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• v.34 no.10
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• pp.757-762
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• 2010

The purposes of this study were to examine the effects of aerobic exercise capacity on free oxygen radicals in blood(FORB) during submaximal exercise in rowing ergometer and as for study purposes, a set of experiments were conducted using one group of 6 rowing players(RP) and the other group of 6 non rowing players(NRP) at the maximum heart rate reserve(HRR) 85~90% exercise intensity. Oxygen free radical was sampled 5 times including a rest period(ARP), immediate after exercise(IAE), 10 minutes after exercise(10MAE), 20 minutes after exercise(20MAE) and 30 minutes after exercise(30MAE). Accordingly, following findings were derived from current study. The effects of interaction between groups and times were significant in oxygen free radical(p<.05) and post hoc tests revealed that significant differences occurred between 10MAE and 20MAE and between 20MAE and 30MAE. In conclusion, the aerobic exercise capacity excellence RP group had more positive recovery pattern than that in the NRP group from FORB of negative influence to the human body

• BMB Reports
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• v.44 no.12
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• pp.787-792
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• 2011

We investigated whether silk fibroin peptide derived from the silkworm, Bombyx mori, could inhibit inflammation and enhance the anti-inflammatory activity of Tat-superoxide dismutase (Tat-SOD), which was previously reported to effectively penetrate various cells and tissues and exert anti-oxidative activity in a mouse model of inflammation. Inflammation was induced by topical treatment of mouse ears with 12-O-tetradecanoylphorbol-13-acetate (TPA). Histological, Western blot, and reverse transcription-polymerase chain reaction data demonstrated that silk fibroin peptide or Tat-SOD alone could suppress elevated levels of cyclooxygenase-2, interleukin-6, interleukin-1beta, and tumor necrosis factor-alpha induced by TPA. Moreover, silk fibroin peptide significantly enhanced the anti-inflammatory activity of Tat-SOD, although it had no influence on in vitro and in vivo transduction of Tat-SOD. Silk fibroin peptide exhibited anti-inflammatory activity in a mice model of inflammation. Therefore, silk fibroin peptide alone or in combination with Tat-SOD might be used as a therapeutic agent for various inflammatory diseases.

• Korean Journal of Microbiology
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• v.45 no.2
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• pp.228-231
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• 2009

We have purified Phytophthora capsici alpha and beta tubulin from Escherchia coli BL21(DE3). The recombinant alpha and beta tubulins were assembled into microtubule in vitro with specific conditions. The metagenome library was isolated from soil in the Mt. Yeo-Ki, Suwon, Korea and manufactured with the method mentioned in experiment contents for in vitro screening of microtubule assembly screening. FRET effect was used for microtubule assembly inhibitor screening with metagenome library. We got 2 metagenome clones from in vitro screening, and these 2 hit clones showed P. capsici growth inhibition activity on the growing pepper plants. These results suggest that new development of potent inhibitor for pepper blight disease and new approach to prevention of pepper blight disease.

• Korean Journal of Materials Research
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• v.10 no.7
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• pp.515-521
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• 2000

The effect of precipitates on the high temperature tensile properties of cast alloy 718 was investigated by phase extraction method and microstructural observation. The value of tensile strength and elongation gradually decreased with increasing testing temperature up to $760^{\circ}C$. Elongation of the alloy increased, while tensile strength decreased above 76$0^{\circ}C$. The amount of precipitates in the specimen that tensile tested at $760^{\circ}C$ showed maximum owing to stress assisted precipitation. Therefore, the alloy exhibited the lowest value of the elongation and the degree of decrease in yield strength at this temperature due to high flow stress of precipitates. Little amount of precipitate, especially $\gamma$' and $\gamma$＂, resulted in softening of the alloy at the temperature above $760^{\circ}C$.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.10
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• pp.6977-6984
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• 2015

It is faced with the necessity of multi roll forming process of the ball slide rail which is made by adding the separate manufacturing processes, piercing, bending, trimming, to the roll forming process of a continuous plastic deformation, to improve the quality. However, the vibration and noise of the press machine in this process leads to the quality degradation of slide rail manufactured in this process. In this study, the roll was designed considering the optimal strain rates by the roll forming program with finite element method. And to estimate the static stability of the multi process the Von-Mises stress and deformation on the press was calculated with a structural analysis program. Also, to avoid driving systems in the resonance region their natural frequencies in the 1st and 2nd mode were calculated through the modal analysis. To verify its dynamic stability improvement the magnitudes of noise and vibration in the existing and studied system were compared using a microphone and accelerometers. And the widths and surface roughnesses of the rails which had been produced in the existing and studied process were measured. Therefore, it is known that multi roll forming process is stable in the analytical and experimental study.

• The Korean Journal of Pain
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• v.9 no.1
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• pp.151-158
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• 1996

Background: Buprenorphine, a new synthetic thebaine derivative, is a partial agonist of the opioid $\mu$-receptor with high receptor affinity, great lipid solubility, and slow rate of opiate receptor association and dissociation. Continuous epidural infusion of opioid can possibly produced undesirable effects, such as respiratory depression, pruritus, etc, in spite of effective postoperative analgesia. Methods: The present study was undertaken to compare the analgesic properties and side effects of continuous epidural infusion of buprenorphine combined with bupivacaine, and morphine combined with bupivacaine in 90 patients following elective gynecologic lower abdominal surgery. At the end of surgery, the initial bolus doses were 3 mg morphine (M group), 0.15 mg buprenorphine (0.15B group), 0.3 mg buprenorphine (0.3B group) combined with 0.25% bupivacaine 10ml, and subsequent continuous infusion doses were 6 mg morphine plus 0.125% bupivacine 100 ml (M group) and 0.6mg buprenorphine plus 0.125% bupivacaine 100 ml (0.15B, 0.3B, group) during 48 hours. The assessment of analgesic efficacy and side effects were made at arrival of recovery room, 1 hr, 4 hr, 8 hr, 24 hr, 36 hr, and 48 hr after the epidural injection. Results: The pain score during 48 hours was significantly higher in the 0.15B group than in the M group and 0.3B group (P<0.05), and the number of patients requiring additional analgesics was significantly higher in the 0.15B group than in the M group and 0.3B group (P<0.05). Signs of respiratory depression were not noted, and the incidence of pruritus, nausea, and vomiting was slightly lower in the 0.15B group and 0.3B group than in the M group, and the incidence of sedation and urinary retention was similar in three group. The subjective rating of satisfaction was better in the 0.3B group than in the M group and 0.15B group (P<0.05). Conclusion: The above results suggest that continuous epidural infusion of buprenorphine combined with low-dose bupivacaine is an advisable method of postoperative analgesia.

• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.8 no.1
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• pp.27-38
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• 2013

Objectives : The purpose of this study is to investigate the latest trends of korean Medicine treatments on traffic accident for recent 5 years. Methods : We investigated the studies on korean Medicine treatments for traffic accident via searching 6 Korean web databases. As a result, 65 research papers were found to be analyzed according to their published year, the titles of journals, the types of study, the number of cases, the sites of injury, the types of treatments the instruments for assessment and ethics approvals. Results : 65 articles were published since 2008. The studies on korean Medicine treatments about traffic accident were mainly published in Journal of Oriental Rehabilitation Medicine. 10 case studies, 14 case series, 11 non randomized controlled trials, 21 randomized controlled trials and 9 systemic reviews had been under research. The most frequently occurred symptoms were neck pain and low back pain. In most studies, various korean Medicine treatments were used to treat the symptoms. Visual analogue scale(VAS) and neck disability index(NDI) were used as primary assessments. In most clinical studies, there were no mention about approval of institutional review board(IRB). Conclusion : In this study, we analyzed the trends of korean Medicine treatments on traffic accident from 2008 to 2012. Reviewing the domestic trends of studies on korean Medicine treatments for traffic accident and examining the strong and weak points of those treatments are essential for the future studies. It is needed to adopt the qualitative methods of evaluation in order to develop a level of evidence.