• 제목/요약/키워드: Division of Fraction

검색결과 1,049건 처리시간 0.032초

말불버섯 추출물의 Topoisomerase 저해 효과 (Inhibition of Topoisomerase-mediated DNA Cleavage by Lycoperdon perlatum)

  • 박미정;조강진;김정봉;김동헌;김양섭;석순자;김선여;황영수
    • 한국식품과학회지
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    • 제29권5호
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    • pp.1057-1062
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    • 1997
  • 26속 32종의 버섯의 topoisomerase II 작용 억제여부를 검색한 결과 말불버섯이 topoisomerase II 작용을 억제하며 그 유효 성분이 핵산분획물에 존재함을 확인하였다. 말불버섯의 핵산분획물은 linear DNA와 open circular DNA를 생성시켰으며 농도와 반응시간에 의존적인 반응 양상을 나타냈다. 또한 말불버섯의 핵산분획물은 topoisomerase I의 작용도 억제하였다. 그러나 배양한 말불버섯의 균사체는 topoisomerase 작용에 아무런 영향을 미치지 않았다.

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Fraction and Mobility of Heavy Metals in the abandoned closed mine near Okdong stream sediments

  • Kim, Hee-Joung;Yang, Jae;Lee, Jai-Young;Jun, Sang-Ho
    • 한국지하수토양환경학회:학술대회논문집
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    • 한국지하수토양환경학회 2003년도 추계학술발표회
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    • pp.56-63
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    • 2003
  • Fractional composition and mobility of sediments some heavy metals in Okdong stream are investigated. The fractional scheme for sediment heavy metal was made for five chemically defined heavy metal forms as adsorbed fraction, carbonate fraction, reducible fraction, organic fraction, and residual fraction (Tessier et at., 1979). The most abundant fraction of the sediment heavy metal is reducible and secondly abundant organic fraction. Adsorbed fraction is minor part of the total heavy metals. Mobilization of sediment heavy metals in stream Okdong is occur 19.8∼56.7% of total cadmium concentrate. The most abundant fraction of the sediment metal is organic fraction in Cu, Pb metals investigated. Labile fraction of sediment metals are 0.5%∼48.5% of total Zn, 2.6%∼48.1% of total Pb, 0.2∼36.9% of total Cu respectively, Most of labile fraction consists of reducible fraction for Cd, Zn, adsorbed fraction for Pb, reducible fraction for Cu, adsorbed fraction for Ni. The Mobilization of Zn and Cu is most likely to occur when oxygen depletes and that of Pb and Ni occurs when physical impact, oxygen depletion and pH reduction.

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초등학생들의 소수 개념과 그 연산에 대한 이해도 분석 (An Analysis on the Students' Understanding in Concept and Operations of Decimal Fraction)

  • 문범식;이대현
    • 한국초등수학교육학회지
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    • 제18권2호
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    • pp.237-255
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    • 2014
  • 본 연구의 목적은 초등학생들의 소수 개념에 대한 이해 정도와 소수 연산에 대한 수행 능력을 분석하여 소수 지도에 대한 교수학적 시사점을 얻고자 함이다. 이를 위해 조사연구를 실시하였고, 156명의 6학년 학생들을 대상으로 하였다. 결과 분석은 각 문항별 정답률과 오류가 많이 발생하는 요소를 살펴보았다. 검사 결과, 초등학생들의 소수 개념과 그 연산에서 85.64%의 정답률을 나타냈고, 소수 개념(89.23%), 덧셈(89.84%), 뺄셈(89.56%) 영역보다 소수의 곱셈(80.73%)과 나눗셈(78.85%) 영역에서 낮은 이해도를 보였다. 소수 개념과 그 연산에 대한 학습이 진행될수록 학습 격차가 더 커진다는 것을 알 수 있었기에 낮은 학년에서부터 점진적으로 학습결손을 줄여주려는 노력이 필요하다. 이에 학습 결손을 해소하기 위한 프로그램이 필요하며, 소수의 교수 학습도 개념과 원리를 중시하는 방향으로 바뀌어야 할 것이다.

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초등학생들이 분수의 나눗셈에서 보이는 반복적 오류 분석 (An Analysis on the Repeated Error Patterns in Division of Fraction by Elementary Students)

  • 김경미;강완
    • 한국수학교육학회지시리즈C:초등수학교육
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    • 제11권1호
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    • pp.1-19
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    • 2008
  • 지금까지 분수의 나눗셈에 대한 오류 분석 연구는 대부분 단 1회의 검사를 통해 분석을 한 후 오류를 검증하였다. 즉, 학생들이 반복적으로 보이는 다양한 오류에 대한 분석한 선행연구는 없었다. 이에 본 연구에서는 수학의 연산 영역 중 초등학교 수학 교육과정의 마지막을 장식한다고도 볼 수 있는 '분수의 나눗셈'에 대한 학생들의 반복적 오류 유형을 살펴봄으로써 학생들의 사고를 엿봄과 동시에 학생들에게 좀 더 신중하고 정확하게 가르쳐야하는 정보를 얻는 것이 목적이다. 이를 위해 6학년 학생들이 분수의 나눗셈을 모두 학습한 후 시간의 흐름에 따라 나타나는 오류를 찾아내기 위해 학생들이 해결한 학습지를 바탕으로 관찰 분석 연구를 진행하였다.

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몫으로서의 분수와 분배전략 (A Study on the Fraction as Quotient and Equal Sharing Strategies in Elementary Mathematics)

  • 이호수;최근배
    • East Asian mathematical journal
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    • 제38권4호
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    • pp.379-396
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    • 2022
  • In this paper, we investigate distribution strategies in the Egyptian fraction, and through this, we examine the distribution strategies of (fraction)÷(fraction) and then provide some educational implications. The (natural number)÷(natural number) of the sharing situation has the meaning of 'share' per unit, which can be seen as a situation where the unit ratio is determined. These concepts can also naturally be extended to the case of (fraction)÷(fraction) by some problem posing situations. That is to say, the case of (fraction)÷(fraction) can be deduced the case (natural number)÷(natural number) by the re-statement of the problem.

신갈나무로부터 유래된 추출물의 Botrytis cinerea 균주에 대한 항균활성 (Antifungal Activity of the Quercus Mongolica Extracts Against Botrytis cinerea)

  • 여희동;이형철;임부국;김희규;최명석;양재경
    • Journal of the Korean Wood Science and Technology
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    • 제36권1호
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    • pp.88-101
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    • 2008
  • 목질자원으로부터 Botrytis속 곰팡이병에 대하여 항균활성을 나타내는 추출물을 탐색하고자 본 연구는 시도되었다. 신갈나무를 고압 전처리하고 이로부터 열수, 메탄올, 에탄올을 이용하여 목질 추출물을 획득하였다. Botrytis속 곰팡이 3종은 $20^{\circ}C$$25^{\circ}C$의 생장온도에서 최적 생장을 하였으며 pH 5.0과 7.0에서 가장 양호한 균사 생장을 나타냈다. 열수 추출물이 Botrytis속에 대하여 가장 우수한 항균활성을 나타내는 것을 확인하였다. 열수추출물로부터 항균물질을 분리하기 위하여 n-hexane : chloroform : ethyl acetate : formic acid (12 : 17 : 8 : 0.2, v/v/v/v)를 용제로 하는 silica-gel column chromatography와 TLC를 사용하였으며, 3종 추출물들은 HPLC 분석을 통하여 화합물을 확인하였으며 UV Spectrophotometer를 이용하여 열수 추출물로부터 6개의 fraction group을 분리 하였다. 6개의 fraction group의 항균활성 test결과, fraction group I과 II는 Botrytis cinerea에 대하여 가장 높은 항균활성을 나타냈다. Fraction group의 HPLC 분석결과, 3개의 유효물질을 확인하였으며 이 3가지 물질이 항균활성에 영향을 미친다고 추측된다.

Evaluation of Antioxidant Activities and Active Compounds Separated from Water Soluble Extracts of Korean Black Pine Barks

  • Shen, Chang-Zhe;Jun, Hong-Young;Choi, Sung-Ho;Kim, Young-Man;Jung, Eun-Joo;Oh, Gi-Su;Joo, Sung-Jin;Kim, Sung-Hyun;Kim, Il-Kwang
    • Bulletin of the Korean Chemical Society
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    • 제31권12호
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    • pp.3567-3572
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    • 2010
  • Black pine barks from the southern region of Korea were extracted using pressurized hot water and the water soluble extracts were then separated in a stepwise fashion using a variety of solvents, column chromatography (CC), thin layer chromatography (TLC), and high pressure liquid chromatography (HPLC). The antioxidant activities of each fraction and the active compounds were determined based on the radical scavenging activities of 2,2-diphenyl-1-picrylhydrazyl (DPPH), reductive potential of ferric ion, and total phenol contents. A DPPH test showed that the half maximal effective concentration ($EC_{50}$ value : $6.59{\pm}0.31\;{\mu}g/mL$) of the ethyl acetate fraction (ca. 0.67%) was almost the same as that of the control compounds and inversely proportional to the value of the total phenol contents. The cell viability of the water extracts was confirmed by methyl thiazol-2-yl-2,5-diphenyl tetrazolium bromide (MTT) with enzyme linked immune sorbent assay (ELISA). Catechin, epicatechin, quercetin and ferulic acid were isolated from the ethyl acetate fraction as active compounds and identified by nuclear magnetic resonance. The antioxidant activity as value of DPPH of each of the separated compounds was lower than the ethyl acetate fraction, and ferulic acid was the lowest among these compounds.

철계 소결합금의 오스테나이트 안정성 (Austenite Stability of Sintered Fe-based Alloy)

  • 최승규;서남혁;전준협;손승배;이석재
    • 한국분말재료학회지
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    • 제27권5호
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    • pp.414-419
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    • 2020
  • In the present study, we investigated the austenite stability of a sintered Fe-based nanocrystalline alloy. The volume fraction of austenite was measured based on the X-ray diffraction data of sintered Fe-based nanocrystalline alloys, which were prepared by high-energy ball milling and spark plasma sintering. The sintered alloy samples showed a higher volume fraction of austenite at room temperature as compared to the equilibrium volume fraction of austenite obtained using thermodynamic calculations, which resulted from the nanosized crystalline structure of the sintered alloy. It was proved that the austenite stability of the sintered Fe-based alloy increased with a rise in the amount of austenite stabilizing elements such as Mn, Ni, and C; however, it increased more effectively with a decrease in the actual grain size. Furthermore, we proposed a new equation to predict the martensite starting temperature for sintered Fe-based alloys.

Anti-Rheumatoid Arthritis Effect of the Kochia scoparia Fruits and Activity Comparison of Momordin Ic, its Prosapogenin and Sapogenin

  • Choi, Jongwon;Lee, Kyung-Tae;Jung, Hyun-Ju;Park, Hee-Sun;Park, Hee-Juhn
    • Archives of Pharmacal Research
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    • 제25권3호
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    • pp.336-342
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    • 2002
  • MeOH extract of Kochia scoparia was fractionated into $CHCl_3-$, EtOAc- and BuOH extracts and the last fraction were hydrolyzed by 3%-NaOH ($MeOH-H_2O$) to compare the bioactivities on antinociceptive and anti-inflammatory effects. Silica gel column chromatography of BuOH fraction afforded a large amount of $3-Ο-{\beta}-D-xylopyranosyl {\;}(1{\rightarrow}3)-{\beta}-D-glucuronopyranosyl$ oleanolic acid (momordin Ic, 4) and that of acid hydrolysate of BuOH fraction gave $3-Ο-{\beta}-D-glucuronopyranosyl oleanolic$ acid (momordin Ib, 3), its 6'-Ο-methyl ester (2) and oleanolic acid (1). Silica gel column chromatography of alkaline hydrolysate afforded a large amount of 4. MeOH extract and both EtOAc- and BuOH fractions were active in the rheumatoidal rat induced Freund's complete adjuvant reagent (FCA) whereas $CHCl_3$ fraction was inactive. Compound 1 and 4 showed significant activities in the same assay but oleanolic acid 3-Ο-glucuronopyranoside (3) showed no activity. These fashions were also observed in carrageenan-induced edema of the rat and in the antinociceptive activity tests undertaken in hot plate- and writhing methods. These results suggest that momordin Ic and its aglycone, oleanolic acid, could be active principles for rheumatoid arthritis.

이온화가스와 활성탄을 이용한 휴믹산 처리에 관한 연구 (The Humic Acid Treatment Characteristics by Ionized Gas and Combination with Activated Carbon)

  • 정팔진;이은주;김민정;조선영
    • 한국물환경학회지
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    • 제20권1호
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    • pp.72-77
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    • 2004
  • Laboratory studies were carried out to find out the characteristics of humic acid treatment by activated carbon and ionized gas, In order to increase oxidation power of ionized gas for treating organic matter, we used granular activated carbon. By using $UV_{254}$, easy analysis method, we calculated humic acid concentration and $SCOD_{cr}$ concentration. For an initial concentration of humic acid, 10, 50 and 100ppm, the reaction rate constant by $UV_{254}$ was $8.98{\times}10^{-3}$/min, $5.62{\times}10^{-3}$/min and $4.8{\times}10^{-3}$/min respectively due to the same flow rate of ionized gas. When we added activated carbon to the ionized gas for humic acid treatment, the reaction rate constant increased in 4.13, 3.65 and 3.15 times. So, by using activated carbon in treating humic acid by ionized gas, oxidation power of organic matter by ionized gas was increased. The hydrophobic fraction constitutes 98% of organic matter for humic acid at the beginning. After the treatment using ionized gas for humic acid, the hydrophobic fraction decreased by 63~65% and the hydrophilic one increased by 35~37%. So, it was proved that the treatment increased the hydrophilic fraction in organic matter.