• Korean Journal of Clinical Laboratory Science
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• v.56 no.1
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• pp.10-20
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• 2024

RNA-sequencing (RNA-seq) is a technique used for providing global patterns of transcriptomes in samples. However, it can only provide the average gene expression across cells and does not address the heterogeneity within the samples. The advances in single-cell RNA sequencing (scRNA-seq) technology have revolutionized our understanding of heterogeneity and the dynamics of gene expression at the single-cell level. For example, scRNA-seq allows us to identify the cell types in complex tissues, which can provide information regarding the alteration of the cell population by perturbations, such as genetic modification. Since its initial introduction, scRNA-seq has rapidly become popular, leading to the development of a huge number of bioinformatic tools. However, the analysis of the big dataset generated from scRNA-seq requires a general understanding of the preprocessing of the dataset and a variety of analytical techniques. Here, we present an overview of the workflow involved in analyzing the scRNA-seq dataset. First, we describe the preprocessing of the dataset, including quality control, normalization, and dimensionality reduction. Then, we introduce the downstream analysis provided with the most commonly used computational packages. This review aims to provide a workflow guideline for new researchers interested in this field.

• The Journal of Korean Academy of Prosthodontics
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• v.62 no.2
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• pp.165-173
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• 2024

Restoring lost teeth is very important in terms of both function and aesthetics. If tooth loss occurs in the posterior region and the loss of support is persistent, it may cause a gradual shift in the position of the mandible and a change in occlusion. This clinical case attempted to restore support for the posterior teeth with a fixed prosthesis using implants in a patient whose opposing teeth were erupted and the occlusal plane collapsed due to long-term loss of the maxillary left posterior teeth and mandibular right first molars. To correct the occlusal plane of remaining dentition, wax-up of maxillary left posterior teeth was duplicated with acrylic resin and placed on maxilla. Surgical template for implant placement were fabricated using digital technology. After the support of the posterior teeth was restored with the placement of the implant, stable occlusion with temporary restorations was observed for a sufficient time. Afterwards, monolithic zirconia prosthesis was placed on the patient to ensure functional and aesthetic improvement.

• The Journal of the Convergence on Culture Technology
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• v.10 no.1
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• pp.51-60
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• 2024

The purpose of this study is to explore the meaning of the 2018 'Comprehensive Plan for the Vitalization of Democratic Citizenship Education' centered on the '2022 Revised Curriculum General Discussion'. Research Results First, in the case of strengthening democratic citizenship education in schools, one of the main tasks in the general discussion of the 2022 revised curriculum emphasizes democratic citizenship education to cultivate citizenship. are doing Second, in the case of teacher professionalism enhancement and support for educational activities, development of teaching and learning materials and reinforcement of teacher training are promoted in the 2022 revised curriculum summary. Third, in the case of creating a democratic school culture, the 2022 revised curriculum outline guarantees student safety and learning rights through remodeling or remodeling old schools to restructure learning spaces and realize a digital-based learning environment. Fourth, in the case of revitalization of student autonomy, in the general discussion of the 2022 revised curriculum, the autonomy of the school curriculum considering the needs of students and school conditions is expanded, and classes centered on participatory experiences and self-government activities are strengthened. Fifth, in the case of establishing a democratic citizenship education support system, the 2022 revised curriculum outline establishes a mutual cooperation system that respects the roles and expertise of various educational subjects and a mutual cooperation system between the local community and the educational community.

• Journal of the Korean Society for information Management
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• v.41 no.1
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• pp.133-162
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• 2024

The rapid digitalization has highlighted the importance of identifying and managing online resources. Especially, the need for a systematic identification system for the efficient distribution and preservation of digital content is growing. This study aims to respond to these contemporary demands by investigating the current state of identification systems for online resources and exploring more systematic management and utilization methods through linking these systems with legal deposit. To achieve this, the study surveyed the identification systems and their issuance status for online resources and analyzed prior research related to these online resources. Based on the analysis, the proposed strategies for linking with legal deposit can be summarized into three categories: First, to prioritize and enhance the utilization of legal deposit, strategies are required to strengthen the mutual complementarity of deposit and use, to assign priorities to certain deposits, and to increase the usability of deposited materials. Second, as strategies based on international standard numbers for linking with legal deposit, it is necessary to integrate ISBN and UCI in the deposit process, to link international standard resource numbers with deposit, to interconnect metadata between international standard numbers and UCI, to integrate UCI and ICN, and to introduce automation technology for upgrading the deposit system. Third, to effectively implement the aforementioned strategies, policy support is essential. This includes enhancing the role of the Korean Bibliographic Standards Center, strengthening cooperation with publishers, compensating for deposited materials, and increasing awareness and institutional compensation for the legal deposit system.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.19 no.3
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• pp.97-107
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• 2024

This study aims to identify the factors that affect customer satisfaction as the market growth of rental subscription services for living environment home appliances increases. Unlike previous research, which focused on online subscriptions (e.g., digital content, over-the-top (OTT) services, e-books, and mobile devices), this study expands the scope to include rental subscriptions for household environmental appliances. Specifically, this study analyzes the factors influencing customer satisfaction among rental subscription service users by examining the effects of perceived usefulness, reliability, and convenience. The results show that users' perceived reliability and convenience of rental subscription services for living environment home appliances significantly affect customer satisfaction. Perceived usefulness, however, was not found to have a significant impact, as it is an abstract and subjective customer aspect. The implications of the results are as follows: First, standardized services must be strengthened to increase the reliability of rental subscription services. Additionally, it is necessary to improve convenience by developing additional services when managing regular visits tailored to the characteristics of each product. Providing customized services by integrating products and Information and Communications Technologies (ICT). Furthermore, effective customer management to increase customer satisfaction is crucial, as it can lead to cross-selling and up-selling opportunities. Lastly, venture start-ups should actively apply a subscription service business model.

• The Mathematical Education
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• v.63 no.3
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• pp.549-571
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• 2024

As digital·AI-based teaching and learning is emphasized, discussions on the educational use of generative AI are becoming more active. This study analyzed the mathematical performance of ChatGPT 4, Claude 3 Opus, and Gemini Advanced on solving examples and problems from five first-year high school math textbooks. As a result of examining the overall correct answer rate and characteristics of each skill for a total of 1,317 questions, ChatGPT 4 had the highest overall correct answer rate of 0.85, followed by Claude 3 Opus at 0.67, and Gemini Advanced at 0.42. By skills, all three models showed high correct answer rates in 'Find functions' and 'Prove', while relatively low correct answer rates in 'Explain' and 'Draw graphs'. In particular, in 'Count', ChatGPT 4 and Claude 3 Opus had a correct answer rate of 1.00, while Gemini Advanced was low at 0.56. Additionally, all models had difficulty in explaining using Venn diagrams and creating images. Based on the research results, teachers should identify the strengths and limitations of each AI model and use them appropriately in class. This study is significant in that it suggested the possibility of use in actual classes by analyzing the mathematical performance of generative AI. It also provided important implications for redefining the role of teachers in mathematics education in the era of artificial intelligence. Further research is needed to develop a cooperative educational model between generative AI and teachers and to study individualized learning plans using AI.

• Journal of Korea Port Economic Association
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• v.40 no.1
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• pp.31-59
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• 2024

In June 2016, the term "Fourth Industrial Revolution" was first used at the World Economic Forum in Davos, Switzerland, and it gained worldwide attention. Consequently, the importance of smart ports has increased as the shipping industry has been incorporating various Fourth Industrial Revolution technologies. Currently, major countries around the world are working to achieve digital transformation in the maritime and port industry by establishing comprehensive smart ports. However, the smartification of domestic ports in South Korea is currently limited to a few areas such as Busan, Incheon, and Gwangyang, focusing on port automation. In this context, this study performed keyword analysis to identify key components of smart ports and conducted Analytic Hierarchy Process (AHP) analysis among relevant stakeholders to determine the priorities for the Introduction of smart ports in South Korea. The analysis revealed that universities prioritized automation, intelligenceization, informatization and environmentalization in that order. Research institutes prioritized informatization, intelligenceization, automation and environmentalization. Government agencies prioritized informatization, automation, intelligenceization and environmentalization, while private sector enterprises prioritized automation, intelligenceization, informatization, and environmentalization.

• Journal of Cerebrovascular and Endovascular Neurosurgery
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• v.26 no.1
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• pp.1-10
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• 2024

Objective: Endovascular coil embolization is the primary treatment modality for intracranial aneurysms. However, its long-term durability remains of concern, with a considerable proportion of cases requiring aneurysm reopening and retreatment. Therefore, establishing optimal follow-up imaging protocols is necessary to ensure a durable occlusion. This study aimed to develop guidelines for follow-up imaging strategies after endovascular treatment of intracranial aneurysms. Methods: A committee comprising members of the Korean Neuroendovascular Society and other relevant societies was formed. A literature review and analyses of the major published guidelines were conducted to gather evidence. A panel of 40 experts convened to achieve a consensus on the recommendations using the modified Delphi method. Results: The panel members reached the following consensus: 1. Schedule the initial follow-up imaging within 3-6 months of treatment. 2. Noninvasive imaging modalities, such as three-dimensional time-of-flight magnetic resonance angiography (MRA) or contrast-enhanced MRA, are alternatives to digital subtraction angiography (DSA) during the first follow-up. 3. Schedule mid-term follow-up imaging at 1, 2, 4, and 6 years after the initial treatment. 4. If noninvasive imaging reveals unstable changes in the treated aneurysms, DSA should be considered. 5. Consider late-term follow-up imaging every 3-5 years for lifelong monitoring of patients with unstable changes or at high risk of recurrence. Conclusions: The guidelines aim to provide physicians with the information to make informed decisions and provide patients with high-quality care. However, owing to a lack of specific recommendations and scientific data, these guidelines are based on expert consensus and should be considered in conjunction with individual patient characteristics and circumstances.

• The Journal of the Convergence on Culture Technology
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• v.10 no.5
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• pp.107-115
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• 2024

Curriculum revision is a very important process for improving students' learning achievement and abilities, responding to social needs, strengthening equality and inclusiveness, strengthening teachers' professionalism, strengthening national competitiveness, and responding to the era of globalization, and for continuous development and innovation. Through this, we can provide better educational opportunities and environments for future generations. The 2022 revised curriculum is a curriculum that reflects the knowledge and skills students need in modern society and enables them to respond to changes in industry and society. The purpose of this study is to present the direction of career education by analyzing the career education shown in the 2022 revised curriculum. If we analyze only the contents related to career education in the 2022 revised curriculum that directly mention career and occupation, the following contents are found. First, in the curriculum for future response, contents related to career education appear in the strengthening of basic digital knowledge. Second, in the field of autonomous innovation support tasks at school sites, the organization of the free semester system and improvement plans are presented among the details of the improvement of flexibility in the operation of the elementary and secondary school curriculum. Third, in the area of strengthening learner-customized education, the core of career education is strengthening career-linked education between elementary, middle and high schools. Career education is mentioned in the area of the detail itself. As such, it is no exaggeration to say that the core content of the 2022 revised curriculum is career education. The direction and contents of career education are faithfully reflected in the 2022 revised curriculum.

• The Journal of the Convergence on Culture Technology
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• v.10 no.5
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• pp.117-126
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• 2024

Lifelong education also plays a big role in promoting social inclusion. By providing equal educational opportunities to people from various social classes, regions, and cultural backgrounds, we reduce social inequality and help all individuals reach their full potential. Through lifelong education, a culture of continuous learning can be established throughout society. The importance of learning will be emphasized, and the attitude of pursuing knowledge and wisdom will become common. The purpose of this study is to suggest a direction for the development of national lifelong education by comparing and analyzing the basic plan for promoting lifelong education from the 1st to the 5th. As a result of the study, it has contributed greatly to the development of national lifelong education by developing the lifelong education promotion basic plan from the 1st to the 5th. If the 5th Basic Plan for Lifelong Education is faithfully implemented, it will contribute to the development of national lifelong education in many areas, and in addition to this, the direction of development of national lifelong education is emphasized. First, the strengthening of the use of digital technology. Second, it is necessary to strengthen cooperation with industries. Third, it is necessary to improve the financial support and scholarship system. Fourth, diversification of curriculum. Fifth, expansion of community participation. Sixth, reinforcement of self-directed learning. Seventh, laws related to lifelong education need to be improved.