• Korean Journal of Radiology
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• v.21 no.11
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• pp.1199-1209
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• 2020

The glymphatic system hypothesis is a concept describing the clearance of waste products from the brain. The term "glymphatic system" combines the glial and lymphatic systems and is typically described as follows. The perivascular space functions as a conduit that drains cerebrospinal fluid (CSF) into the brain parenchyma. CSF guided to the perivascular space around the arteries enters the interstitium of brain tissue via aquaporin-4 water channels to clear waste proteins into the perivascular space around the veins before being drained from the brain. In this review, we introduce the glymphatic system hypothesis and its association with fluid dynamics, sleep, and disease. We also discuss imaging methods to evaluate the glymphatic system.

• Journal of the Korean Society of Radiology
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• v.81 no.6
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• pp.1412-1423
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• 2020

Purpose Some patients with neonatal seizures show diffuse, symmetric diffusion-restricted lesions in the cerebral white matter. The aim of this study was to describe clinical and imaging findings of patients with neonatal seizures who had diffuse, symmetric diffusion-restricted lesions without any structural or metabolic etiology. Materials and Methods A total of 56 neonates aged less than 1 week underwent brain magnetic resonance imaging (MRI) for evaluation of seizures from November 2008 to February 2017. After excluding 43 patients, 13 patients showed diffuse white matter abnormality on diffusion-weighted imaging. Initial and follow-up clinical and MRI findings were analyzed retrospectively. Results All 13 patients were born at full term. Among the ten patients who underwent a stool test for viruses, six were positive for rotavirus and one for astrovirus. MRI revealed diffuse, symmetric diffusion-restricted lesions distributed along the cerebral white matter, thalami, and midbrain variably. Conclusion Diffuse, symmetric diffusion-restricted lesions involving the cerebral white matter can be seen in patients with neonatal seizures without any structural or metabolic etiology. Rotavirus is commonly but not exclusively detected in these patients. Nevertheless, viral infection-associated encephalopathy should be considered for patients with characteristic clinical and MRI findings.

• Transactions of the Korean Society of Mechanical Engineers
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• v.16 no.10
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• pp.1940-1954
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• 1992

Fine grid computations were attempted to analyze the turbulent flows in the near wall low Reynolds number region and the numerical analyses were incorporated by a finite-volume discretization with full find grid system and low Reynolds number k-.epsilon. model was employed in this region. For the improvement of low Reynolds number k-.epsilon. model, modification coefficient of eddy viscosity $f_{\mu}$ was derived as a function of turbulent Reynolds number $R_{+}$ and nondimensional length $y^{+}$ from the concept of two length scales of dissipation rate of turbulent kinetic energy. The modification coefficient $f_{\epsilon}$ in .epsilon. transport equation was also derived theoretically. In the turbulent kinetic energy equation, pressure diffusion term was added in order to consider low Reynolds number region effect. The main characteristics of this low Reynolds number k-.epsilon. model were founded as : (1) In high Reynolds number region, the present model has limiting behavior which approaches to the high Reynolds number model. (2) Present low Reynolds number k-.epsilon. model dose not need additional empirical constants for the transport equations of turbulent kinetic energy and dissipation of turbulent kinetic energy in order to consider wall effect. Present low Reynolds number turbulence model was tested in the pipe flow and obtained improved results in velocity profiles and Reynolds stress distributions compared with those from other k-.epsilon. models.s.s.

• Journal of the Korean association of regional geographers
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• v.1 no.1
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• pp.103-116
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• 1995

The purpose of this paper is to explore a brief review of trends in existing geographical research on music and to analyze music by the 5 themes of geography and to explore a variety of classroom techniques which examine song lyrics for their geographic content. The results of this paper are summarized as followed : Firstly, the trends in geographical research on music can be classified into five areas, the first is on spatial diffusion in music, the second on spatial diffusion in music, the third on regional division in music, the fourth on regional characteristics in music, the fifth on pedagogical tools in the teaching of geography. Secondly, music holds numerous possibilities for regional geographical study. The lyrics of music are littered with geographical term through which song writers impart image of culture, the distinct geographical nature of music lyrics gives rise to many geographical question, also, music lyrics gives place its special character. The results of analyses by the 5 themes of geography indicate that music are useful to learning of regional geography. The application of music to learning regional geography attracts much attentions. In the respect of importance of learning new regional geography, and in the respect of adapting globalization have to be focused on this subject.

• Journal of Korea Game Society
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• v.9 no.5
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• pp.137-144
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• 2009

This paper predicts 6 facial regions that may have sharply different scattering properties, rendering the face more realistically based on their diffusion profiles. The scattering properties are acquired in the form of high dynamic range by photographing the pattern formed around an unit ray incident on facial skin. The acquired data are fitted to a 'linear combination of Gaussian functions', which well approximates the original diffusion profile of skin and has good characteristics as the filter. During the process, to prevent its solutions from converging into local minima, we take advantage of the genetic algorithm to set up the initial value. Each Gaussian term is applied to the irradiance map as a filter, expressing subsurface scattering effect. In this paper, to efficiently handle the maximum 12 Gaussian filterings, we make use of the parallel capacity of CUDA.

• Membrane and Water Treatment
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• v.8 no.5
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• pp.449-462
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• 2017

Direct treatment of municipal wastewater by forward osmosis (FO) process was evaluated in terms of water flux decline, reverse salt diffusion, pollutants rejection and concentration efficiency by using synthetic seawater as the draw solution. It was found that when operating in PRO mode (active layer facing the draw solution), although the FO membrane exhibited higher osmotic water flux, more severe flux decline and reverse salt diffusion was also observed due to the more severe fouling of pollutants in the membrane support layer and accompanied fouling enhanced concentration polarization. In addition, although the water flux decline was shown to be lower for the FO mode (active layer facing the feed solution), irreversible membrane fouling was identified in both PRO and FO modes as the water flux cannot be restored to the initial value by physical flushing, highlighting the necessity of chemical cleaning in long-term operation. During the 7 cycles of filtration conducted in the experiments, the FO membrane exhibited considerably high rejection for TOC, COD, TP and $NH_4{^+}-N$ present in the wastewater. By optimizing the volume ratio of seawater draw solution/wastewater feed solution, a concentration factor of 3.1 and 3.7 was obtained for the FO and PRO modes, respectively. The results demonstrated the validity of the FO process for direct treatment of municipal wastewater by using seawater as the draw solution, while facilitating the subsequent utilization of concentrated wastewater for bioenergy production, which may have special implications for the coastline areas.

• KIEAE Journal
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• v.17 no.3
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• pp.119-124
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• 2017

Purpose: Groundwater heat pump (GWHP) system has high coefficient of performance than conventional air-source heat pump system and closed-loop type geothermal system. However, there is problem in long-term operation that groundwater raise at the diffusion well and reduced at the supply well. Therefore, it is necessary to accurately predict the groundwater flow, groundwater movement and control the groundwater level in the wells. In this research, in consideration of hydrogeological characteristic, groundwater level and groundwater movement were conducted analysis in order to develop the optimal design method of the two-well system using the pairing pipe. Method: For the optimum design of the two-well system, this research focused on the design method of the pairing pipe in the simulation model. Especially, in order to control the groundwater level in wells, pairing pipe between the supply well and diffusion well was developed and the groundwater level during the system operation was analyzed by the numerical simulation. Result: As the result of simulation, the groundwater level increased to -2.65m even in the condition of low hydraulic conductivity and high pumping flow rate. Consequently, it was found that the developed system can be operated stably.

• STI Policy Review
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• v.8 no.1
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• pp.113-156
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• 2017

Although technological progress is considered a key element for economic growth and development of a country, strong empirical evidence in this regard is not available yet. Therefore, to establish the empirical link between technology progress and economic development, it is advisable to carry out a time series analysis. In this regard, the Technology Achievement Index (TAI) of 100 top economies has been developed to examine the position of countries' technological progress for the 21 years spanning 1995 to 2015. Countries have been ranked on their TAI which is based on four pillars; technology creation, diffusion of older innovations, diffusion of recent innovations, and development of human skills. As well, this current study re-calculates the Humane Development Index (HDI) of 100 top economies for the 21 years from 1995 to 2015. Ranking of countries' HDI values reflects three dimensions: A long lifespan (life expectancy index), knowledge (Education Index) and a decent standard of living (Gross National Income Index, or GNI). The Standard Deviation (SD) technique has been used to investigate the technological gap between individual countries and groups of countries or regions. For a more meaningful assessment, technological gaps from the maximum achievement value (i.e., one of the countries under study) are presented as well. To investigate the impact of technological progress on economic development, this study introduces a model in which the HDI is used as the dependent variable and the TAI and Gross Capital Formation (GCF) are used as independent variables. The HDI, TAI and GCF are used in this model as proxy variables for economic development, technological progress and capital respectively. Econometric techniques have been used to show the impact of technological progress on economic development. The results show that long-term associations exist between technology progress and economic development; the impact of technology progress on economic development is 13.2% while the impact is 4.3% higher in eight selected East South Asian countries, at 13.5%, than in eight selected highly developed countries (9.2%).

• Transactions of the Korean Society of Mechanical Engineers B
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• v.20 no.1
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• pp.304-320
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• 1996

A multiple production .epsilon. equation model was developed in the low Reynolds number $\kappa$-$\varepsilon$ model with the aids of DNS data. We derived the model theoretically and avoided the use of empirical correlations as much as possible in order for the model to have generality in the prediction of complex turbulent flow. Unavoidable model constants were, however, optimized with the aids of DNS data. All the production and dissipation models in the $\varepsilon$ equation were modified with damping functions to satisfy the wall limiting behavior. A new $f_{\mu}$ function, turbulent diffusion and pressure diffusion model for the k and .epsilon. equations were also proposed to satisfy the wall limiting behavior. By, computational investigation on the plane channel flows, we found that the multiple production model for .epsilon. equation could improve the near wall turbulence behavior compared with the standard production model without the complicated empirical modification. Satisfication of the wall limiting conditions for each turbulence model term was found to be most important for the accurate prediction of near wall turbulence behaviors.

• Journal of Ocean Engineering and Technology
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• v.28 no.3
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• pp.245-253
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• 2014

This research analyzed the current situation and problems with an environmental impact assessment to provide a rational ocean physics assessment technique for power plant thermal effluent. This research also tried to create an improvement plan for heated effluent diffusion impact assessment by examining the reporting regulations for environmental impact assessment, national and international evaluation guidelines, etc. In the case of evaluating the oceanographic impact of heated effluent discharged from power plants, a pre-investigation is necessary before a full-scale presentence investigation, to accurately predict and minimize power plant construction effects on the surrounding environments. Before this presentence investigation, moreover, an integrated presentence plan, which agrees with the business plan, effect prediction, and post-investigation, needs to be established. A sufficient summit investigation must be made, which considers climate changes, and new and additional power plant construction. For accurate long-term oceanic environmental change prediction, the credibility of effect prediction must be elevated by presenting an evaluation method that is categorized by numerical organization models, verification methods, result presentation, and other things. Furthermore, unproductive conflicts between the people involved in heated effluent evaluation should be reduced by these improvement plans.