• Journal of Life Science
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• v.28 no.6
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• pp.738-744
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• 2018

Sasa quelpaertensis Nakai is a native Korean plant that grows only on Mt. Halla of Jeju Island. Its leaf is used for a popular bamboo tea due to its various health-promoting properties, and it has been increasingly used as food and cosmetic ingredients. To utilize the S. quelpaertensis leaf efficiently, the preparation method for phytochemical-rich extract (PRE) using the leaf's residue was previously reported, which was produced after hot water extraction. This study was undertaken to evaluate the anti-oxidant and anti-inflammatory potential of PRE and its solvent fractions. The ethyl acetate fraction of PRE (EPRE) showed higher DPPH, ABTS, and superoxide radical scavenging activities, and it effectively inhibited intracellular reactive oxygen species (ROS) and nitric oxide (NO) production in lipopolysaccharides (LPS)-stimulated RAW 264.7 cells. EPRE also induced the expression of heme oxygenase-1 (HO-1) by increasing the level of nuclear factor E2-related factor 2 (Nrf2) in a nuclear fraction. The inhibiting effect of EPRE on LPS-induced NO production was partially reversed by the HO-1 inhibitor (zinc protoporphyrin, ZPP), suggesting that HO-1 is involved in suppressing NO production. Taken together, the results suggest that EPRE has potential as a promising anti- oxidant and anti-inflammatory agent.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.5
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• pp.216-222
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• 2020

Tumor necrosis factor receptor associated factor 4 (TRAF4) is found to be overexpressed in human breast cancer. It plays a role in cancer metastasis, production of reactive oxygen species, and cell polarity at membranes. The characteristics and functions of TRAF4 in pigs have not yet been identified. As the first step of research, the mRNA sequence of TRAF4 in porcine cells has been determined. To obtain the full-length sequence, rapid amplification of cDNA ends (RACE) has been carried out. Upon cloning, 2,030 bp of nucleotides were found to encode 470 amino acids, and 8 and 12 amino acids were different from those of the human and mouse TRAF4, respectively. The coding region of porcine TRAF4 was shown to be 93% and 90% homologous to human and mouse TRAF4, respectively. qPCR was conducted to determine the relative expression level of TRAF4. TRAF4 expression in pK15 was enhanced by cell-cell contacts. The mRNA levels of CLDN4, OCLN, and TJP1 at 60% and 80% confluency were significantly higher than at 40% confluency. Further, TRAF4 and tight junction-related genes were down-regulated upon treatment with TRAF4 siRNA. Thus, TRAF4 may affect the function of tight junctions in pig.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.45 no.1
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• pp.49-56
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• 2019

Pueraria thomsonii Benth. as a medicinal ingredient, has been traditionally used in Chinese medicine to treat fever, acute dysentery, diarrhea, diabetes, and cardiovascular disease. The effects of P. thomsonii flower on skin have not been reported yet. In this study, the whitening effect of P. thomsonii flower was verified using B16F1 melanoma cells and HS68 fibroblasts. P. thomsonii flower extract reduced melanin contents of B16F1 cells in a dose-dependent manner. To identify its active components, we analyzed P. thomsonii flower extract using high performance liquid chromatography (HPLC). As a result, we identified three major isoflavones of tectorigenin, tectoridin, and tectorigenin 7-O-xylosylglucoside. At a non-cytotoxic concentration, the three components also reduced melanin contents of B16F1 cells in a dose-dependent manner. The depigmentation effects were attributed to the reduced gene expression of tyrosinase and microphthalmia-associated transcription factor (MITF). In order to elucidate another depigmentation mechanism, their effects on DKK-1, a fibroblast-derived depigmentation factor, was determined in HS68 cells. As a result, P. thomsonii flower extracts, tectoridin and tectorigenin 7-O-xylosylglucoside, reduced DKK-1 gene expression, while tectorigenin increased DKK-1 gene expression in a dose-dependent manner. These results suggest that tectorigenin can be used as an effective whitening agent that inhibit melanin synthesis in melanocytes and promote the secretion of depigmentation factor from fibroblasts.

• Journal of the Korea Society of Computer and Information
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• v.23 no.2
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• pp.109-116
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• 2018

By November 2017, the number of overseas travelers of the Korean nationals reached a cumulative total of 2,409,155, bringing about 26 million overseas travelers. For Korea's future growth and development, it is necessary to make the country much more attractive than now, and to enhance the competitiveness of the domestic tourism field and attract the people of the world. The purpose of this study is to analyze the satisfaction of tourism policy and to utilize it in the development of tourism policy through the empirical analysis of the satisfaction of the tourism resource development and the tourism development policy in Korea. The policy that can achieve the policy purpose pursued by the regional tourism resource development and the future regional tourism resource development and development policy plan were suggested. It is necessary to consider factors related to development of tourism resources such as policy factors, development factors, management factors, and environmental factors. Local tourism development policies should be made considering the factors related to tourism policy expectation, regional characteristics, cultural characteristics and environmental characteristics. In addition, the global competitiveness of the tourism industry and enterprises should be strengthened through the protection of companies and rationalization of tourism related regulations in relation to the opening and expansion of the global tourism market scale.

• Journal of the Korean Society for Library and Information Science
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• v.40 no.3
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• pp.99-120
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• 2006

This study is conformed to having library anxiety of our domestic university library users. and. to developing the Korean Library Anxiety Scales(K-LAS). The research methods is literature research. library use Postscript report analysis. and questionnaire survey. The research subjects were selected to be 4 universities in consideration of their student number and library scale. The research period was from September 3, 2005 to March 23. 2006. The questionnaire survey was administered in the liberal arts courses which all the students could take. The development method of the Library Anxiety Scale are the content validity test by expert group. reliability test and validity test of SPSS Program. Also. the correlation between library variables and library anxiety was tested by using K-LAS. The results of this study developed the K-LAS. which was composed of 6 factors and 40 items. 6 factors were set up as physical environmental factor, library use and knowledge factor, task and research factor. digital information factor, and the factor on library staff. and Psychological ? emotional factor. According to the Post-test results of the correlation between library anxiety and variables. 5 factors except the factor on library staff were correlated with more than 2 variables respectively.

• Journal of the Korean Association of Geographic Information Studies
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• v.15 no.3
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• pp.13-22
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• 2012

The spatial structure analysis using the existing space syntax has a weakness only to apply the road factor. Hence, it is necessary to perform a new spatial structure analysis considering the regional characteristics factor as well as the road factor. The purpose of this study is to propose a modified spatial structure analysis which adopts road and regional characteristics factors using the existing space syntax and GIS and then to apply it to the spatial structure analysis of the urbanized areas in Hapdeok town. For the new analysis, the experts' survey has been conducted to derive the spatial structure factors of the area and their relative weights. Specifically, it drew the road factor as well as the regional characteristics factors such as road, district, land value, and building density. This study shows that the existing spatial structure analysis considering only the road factor does not reflect the actual spatial structure but the modified spatial structure analysis considering the road factor and the regional characteristics factors more accurately analyzes the spatial structure of Hapdeok town. Hapdeok is not an area where road networks were developed along main development axis and its centrality was changed, but an area where road networks were developed by effectiveness and equity and its centrality was changed by downtown decline. The towns like Hapdeok is more suitable for applying the modified spatial structure analysis method considering the regional characteristics factors. Further research is required for selecting characteristics factors and appropriate parameters in the modified spatial structure analysis. Further case studies await in other cities for conducting its verification.

• Journal of Korean Elementary Science Education
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• v.40 no.3
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• pp.366-389
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• 2021

The purpose of this study is to extract the factors that compose the image of science teacher desired by elementary school students in inquiry-based instruction and analyze the structural associations between them. Factors that compose the image of science teacher desired by elementary school students in inquiry-based instruction were extracted through exploratory factor analysis (EFA). Based on the findings of EFA, the questionnaire has been further analyzed using confirmatory factor analysis (CFA). In addition, based on the factor structure identified through factor analysis, we comprehensively analyzed the image of science teacher desired by elementary school students in inquiry-based instruction. As a result of EFA, five factors were identified which compose the image of science teacher desired by elementary school students in inquiry-based instruction: namely, teaching strategy, assessment strategy, prior guidance, understanding students, learning development. The CFA results showed a relatively strong correlation between teaching strategy and learning development, teaching strategy and understanding students. As a result of a comprehensive review of students' perception of the image of science teachers in inquiry-based instruction based on the extracted factor structure, students perceived that it is important for science teachers to run inquiry-based instruction by reflecting their understanding of students. Students also perceived importantly that science teachers run inquiry-based instruction using effective teaching strategies and proper evaluation strategies.

• Journal of the Korea Fashion and Costume Design Association
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• v.21 no.3
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• pp.13-24
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• 2019

Adolescence is a transitional stage of physical development which occurs during the period from puberty to adulthood. Going through this period, various parts of an adolescent's body grow at different rates, leading to different body shapes and proportions when compared to adults. Therefore, this study aimed to investigate the body sizes and shapes of junior high school boys from ages 13-15 based on body measurement items that are used as the basis for school uniform designs including jackets, shirts, and pants. For this, the study sought the basic data needed to develop body shapes and school uniform patterns for junior high school boys using the data from the 6th Size Korea Survey (2010). Specifically, it provided basic data for the development of school uniform patterns that fit well through the classification of bodies into particular types. After extracting body shape componen a cluster analysis using ANOVA was performed. According to the factor analysis conducted to determine body shape components, 5 factors were obtained as follows: Factor 1: bulk and horizontal size, Factor 2: body height and length, Factor 3: shoulder shape and length, Factor 4: characteristics of horizontal size, Factor 5: shape of the upper body with a variance of 82.62%. To classify junior high school boys' body shape was determined using various characteristics, and a cluster analysis was performed with the variables obtained by the factor analysis. For this, body shapes were classified into 3 different types: Type 1 accounted for 33.4%, with a total of 463 subjects. This type was a tall, long body individual with the smallest bulk and size. Type 2 accounted for 22.7%, with a total of 315 subjects. This type was large in bulk and horizontal size, but the lowest in height and length. Type 3 accounted for 43.9%, with a total of 610 subjects. This type was close to average in terms of horizontal size, length, and height. To develop well-fitting school uniforms for junior high school students, there should be further studies on changes in body shape and their associated causes. The study results will be available as basic data for comparing branded school uniform patterns for junior high school boys and developing school uniform patterns based on body shape, using 3D virtual clothing simulations.

• Journal of Practical Engineering Education
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• v.15 no.1
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• pp.1-11
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• 2023

The purpose of this study is to develop and validate a tool that measures the satisfaction of virtual training learners' use of virtual training content. To this end, 491 copies of the basic questions derived from the satisfaction questions used by the K University Online Lifelong Education Center were used for the final analysis by conducting an online survey of learners who accessed STEP, the K University Online Lifelong Education Center portal. The 491 copies of data finally used were analyzed by methods such as basic question analysis, exploratory factor analysis, reliability analysis, and confirmatory factor analysis. First, in the basic question analysis, there were no questions that exceeded the acceptance criteria of an average of 4 points or more, skewness ±2, and kurtosis ±4. Second, the correlation coefficient for each sub-factor of virtual training content satisfaction derived after exploratory factor analysis was good as r=.682 to .822 (p<.01). The reliability coefficient for each sub-factor is content .849, content utilization .922, System and Operations Support .841, Intention to Continue Utilization .920, the overall reliability is. It was very high at .956 Fifth, as a result of confirmatory factor analysis, the compositional conceptual diagram is. It was .842 to .926, higher than the recommended standard of .7, and the average variance extraction degree. It appears to be .640 to .796, higher than the recommended standard of .5, which can be seen as representative of each constituent concept. As a result of verifying the validity of virtual training learners' content satisfaction recruitment, four factor models were derived: content substance, content utilization, system and operation support, and intention to continue use. This study is meaningful in that it empirically developed a tool to measure content satisfaction of virtual training learners and provided a reference frame and criteria.

• Journal of the Korea institute for structural maintenance and inspection
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• v.23 no.2
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• pp.67-74
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• 2019

In this paper the response factor is investigated for middle and small size-RC slab aged bridges. The response factor consists of static and dynamic response factors and is a main parameter in the frequency based-bridge load carrying capacity prediction model. Static and dynamic response factors are determined based on the frequency variation and the impact factor variation respectively between current and previous (or design) states of bridges. Here, the impact factor variation is figured out using the impact factor response spectrum which provides the impact factor according to the natural frequency of bridges. In this study, four actual RC slab bridges aged over 30 years after construction are considered and their span length is 12m. The dynamic loading test in field using a dump truck and eigenvalue analysis with FE models are conducted to identify the current and previous (or design) state-natural frequencies of the bridges, respectively. For more realistic considerations in the moving loading situation, the impact factor response spectrum is developed based on tri-axle moving loads representing the dump truck load distribution and various supporting conditions such as simply supported and both ends fixed conditions. From the results, the response factor is widely ranged from 0.21to 0.91, showing that the static response factor contributes significantly on the results while the dynamic response factor has a small effect on the result. Compared to the results obtained from the impact factor response spectrum based on the single axle-simply supported condition, the maximum percentage difference of the response factors is below 3.2% only.