• Title/Summary/Keyword: Development factor

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An Analysis on Global Terminal Operator's Selection of Container Terminal -Focusing on the Chinese Container Ports- (GTO의 신규터미널 후보지 선택에 관한 연구 -중국 컨테이너 항만을 중심으로-)

  • Yeo, Gi-Tae;Jung, Hyun-Jae;Pak, Ji-Young
    • Journal of Korea Port Economic Association
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    • v.28 no.1
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    • pp.159-178
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    • 2012
  • Recently, Global network expansion strategy of GTOs(Global Terminal Operator) coupled with each country's port policy, plays huge role for the evolution of modern container port. The Chinese ports can be regarded as the major markets to the GTOs. However, there are scant of researches for finding the key success factors of GTOs' strategies when they consider to invest in overseas. In this respect, the aims of this study were to draw out the evaluation variables for successful investment strategies of GTOs, and to calculate the selected target ports. The 14 variables are selected including the variable named 'development potentiality of a port' through literature reviews. Using the Factor Analysis (FA) based on selected variables, four principal factors were extracted such as 'ability for port operating and cargo generating', 'the trade route and volume', 'the calling potentiality for large vessels' and 'the possibility of utilization of existing infrastructure'. In addition, the weights of factors and variables are evaluated through Fuzzy AHP method. As a result, 'ability for port operating and cargo generating' is chosen as the most important factor among principal factors as scored 0.343, and 'the development potentiality of a port' (0.107) is represented as the most important variable among 14 detailed variables. In overall, from the Global Terminal Operator's point of view, Shanghai is ranked as most suitable port for operating new terminal among the top 5 Chinese ports.

Panax ginseng total protein promotes proliferation and secretion of collagen in NIH/3T3 cells by activating extracellular signal-related kinase pathway

  • Chen, Xuenan;Wang, Manying;Xu, Xiaohao;Liu, Jianzeng;Mei, Bing;Fu, Pingping;Zhao, Daqing;Sun, Liwei
    • Journal of Ginseng Research
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    • v.41 no.3
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    • pp.411-418
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    • 2017
  • Background: Recently, protein from ginseng was studied and used for the treatment of several kinds of diseases. However, the effect of ginseng total protein (GTP) on proliferation and wound healing in fibroblast cells remains unclear. Methods: In this study, cell viability was analyzed using the MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] assay. Cell cycle distribution was analyzed by flow cytometer. The levels of transforming growth factor ${\beta}1$, vascular endothelial growth factor, and collagens were analyzed by enzyme-linked immunosorbent assay and immunofluorescence staining. The expressions of cyclin A, phosphorylation of extracellular signal-related kinase (p-ERK1/2), and ERK1/2 were analyzed by Western blotting. Results: Our results showed that GTP promoted cell proliferation and increased the percentage of cells in S phase through the upregulation of cyclin A in NIH/3T3 cells. We also found that GTP induced the secretion of type I collagen, and promoted the expression of other factors that regulate the synthesis of collagen such as transforming growth factor ${\beta}1$ and vascular endothelial growth factor. In addition, the phosphorylation of ERK1/2 at Thr202/Tyr204 was also increased by GTP. Conclusion: Our studies suggest that GTP promoted proliferation and secretion of collagen in NIH/3T3 cells by activating the ERK signal pathway, which shed light on a potential function of GTP in promoting wound healing.

Development of a Gifted Behavior Checklist Based on the Observation Probability and Importance of the Behavior in Class (관찰가능성과 중요도를 고려한 관찰·추천용 초등 영재 행동 특성 체크리스트 개발)

  • Lee, In-Ho;Han, Ki-Soon
    • Journal of Gifted/Talented Education
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    • v.25 no.6
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    • pp.817-836
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    • 2015
  • This research focuses on the development of gifted child behavior checklist which feasibly has application on the nation-wide gifted children observation-recommendation method. Corresponding measure has significance as it reflects actual observations of teachers teaching gifted children first-hand and involves measure of importance regarding each characteristic. An open survey on gifted children behavior characteristics lists and specific behavior patterns has been acquired from teachers in gifted education, and the checklist was developed through expert group review, pre-test, and confirmatory factor analysis process. The former checklists have shown several difficulties on application of observation-recommendation on the field due to behaviors that can't be observed in school, less important behaviors, and collide and duplicate behaviors etc. With regard to such problems, problematic clauses were removed based on the observation probability and importance of the behaviors. Ultimately, total of 32 behavior characteristic checklist consisting of ten sub factors(logical thinking, high achievement, originality, perfectionism, creative problem solving, curiosity, task commitment, conversation ability, creativity, passion) and two to three questions on each factor had been drawn. Through internal consistency test and item-total score correlation, each item of the measure has been analyzed to be consistently evaluating corresponding variables. In addition, the result of confirmatory factor analysis showed every item to be weighed appropriately on its sub-factor, strongly suggesting its feasibility on observation-recommendation of elementary gifted children as an appropriate checklist.

Development of Clinical Competency Self-Report Scale for Clinical Satisfaction of Occupational Therapy Student (작업치료대학생의 실습만족을 위한 임상수행능력 자기보고식 척도 개발)

  • Lee, Min-Jae;Lee, Sun-Min
    • Journal of Korea Entertainment Industry Association
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    • v.14 no.1
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    • pp.137-147
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    • 2020
  • This study is aimed to develop and validate the clinical competence scale of occupational therapy student. The development of clinical competence scale analyzed the definition of clinical performance and previous studies. preliminary examinations were conducted on 203 occupational therapy departments in 3rd and 4th grade to verify item analysis and job validity. After exploratory factor analysis, eight factors of professional consciousness, 11 items of occupational therapy evaluation factors, 4 items of occupational therapy intervention factors, and 4 items of communication factors were extracted into a total of 27 factors. As a result of verifying the reliability of each factor through the internal consistency coefficient Cronbach's α, it was found to be .87~.94 and the overall reliability was .96. The correlation between the total score and the factors of the clinical competence scale was statistically significant. Through the confirmatory factor analysis, the model fit test of the factor structure for 27 items of 4 factors (χ2=.76, df = .31, CFI = .81, TLI = .80, RMSEA = .79) is considered acceptable. Through this study, The clinical competence scale is a valid and reliable scale that can be useful for objectively assessing.

A Study on the Social Effects of Local Living Culture Activities in Daejeon (지역 생활문화활동의 사회적 효과에 관한 연구 : 대전광역시를 중심으로)

  • Lim, Jaehyun;Han, Sangheon
    • 지역과문화
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    • v.6 no.3
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    • pp.55-77
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    • 2019
  • This study analyzed social effects of participating in living culture activities for Daejeon citizens. The social effects were set to creativity and self-esteem at the individual factor and community involvement and exchange at the social factor, this effects were tested by the method of participation in living culture activities. We used SPSS 22 to analyze this effects, factor analysis, analysis of variance, and logistic regression analysis were used. The results showed that participation in lecture programs increased the effects of community involvement and exchange at the social factor. Participation in the club activities showed a decrease in creativity, and further analysis of the club activities was necessary. Participation in cultural art events increases self-esteem. Participation in performances and exhibitions of cultural art events increased creativity. Through these analysis results, first, development of living cultural programs to improve the characteristics of local residents and community of village culture. Second, revitalization through support of various community club activity programs. Third, support for the formation of village cultural community through exchange and cooperation between local Culture and Art Activists and local residents. Fourth, development and expansion of living-oriented and generation-integrated living cultural programs for young and old generations.

A Comparative Study of the Perceptions by Stakeholder on the Problems and Difficulties at Implementation Stages of the Agricultural Environment Conservation Program (농업환경보전프로그램 이행단계별 문제점 및 애로사항에 대한 이해당사자별 인식 비교)

  • Kim, Soo-Jin;Bae, Seung-Jong;Yoo, Seung-Hwan;Na, Ra;Son, Jeong-Woo;Hur, Seung-Oh
    • Journal of Korean Society of Rural Planning
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    • v.29 no.4
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    • pp.201-210
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    • 2023
  • The Agricultural Environmental Conservation Program is a useful system for creating sustainable agriculture and environmentally friendly and comfortable rural areas. However, there are still many problems and difficulties, such as the establishment of necessary activities and plans by the residents themselves, and improvements are required. The degree of importance and difficulties according to the implementation stage of each stakeholder was quantified and compared with each other, and the specific difficulties recognized by on-site support organizations were structurally analyzed. It was analyzed that the importance and difficulties of the project implementation stage for local government officials and the project implementation planning stage for on-site support organizations were very high, indicating that they perceived the most need for improvement. On the other hand, 21 specific problems and difficulties were derived based on the results of the literature survey and stakeholder interviews. As a result of the structural analysis using the DEMATEL method, the most influential factor was the low understanding of the project by residents, the most influential factor was the lack of collecting and reflecting residents' opinions, the most central factor was the lack of collecting and reflecting residents' opinions, and the most causal factor was the lack of education and promotion of the project. The results indicate that a more stable system can be established if continuous promotion and education, periodic meetings and discussions, active reflection of residents' opinions in project implementation plans, and simplification of implementation inspection and project cost execution through the implementation inspection platform are promoted. Despite the limitations, considering that no institutional analysis of agricultural environmental conservation programs has been conducted so far, the results of this study are expected to serve as a basis for the establishment of relevant policies in the future.

Disease-resistant Transgenic Arabidopsis Carrying the expI Gene from Pectobacterium carotovorum subsp. carotovorum SL940

  • Lee, Joo-Hee;Hong, Ja-Bin;Hong, Sang-Bin;Choi, Min-Seon;Jeong, Ki-Yong;Park, Hyoung-Joon;Hwang, Duk-Ju;Lee, Seung-Don;Ra, Dong-Soo;Heu, Sung-Gi
    • The Plant Pathology Journal
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    • v.24 no.2
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    • pp.183-190
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    • 2008
  • Plant-cell-wall-degrading enzymes (PCWDEs) of Pectobacterium carotovorum subsp. carotovorum are the key virulence factor in pathogenesis of soft rot disease of vegetables. The production of PCWDEs is controlled in a cell density dependent manner to avoid the premature production of PCWDEs and subsequent activation of plant defense. N-oxoacyl-homoserine lactone (OHL) is essential for quorum sensing in the soft rot pathogen and the expI gene is responsible for OHL production. The ExpI homolog isolated from P. carotovorum subsp. carotovorum SL940 had 94% identity with ExpI of E. carotovora subsp. carotovora scc3193 and 74% identity with Carl of E. carotovora subsp. atroseptica. The transgenic plants that express exp I uner the control of CaMV35S promoter were able to produce diffusible OHL. Transgenic plants producing OHL were very resistant to the infection of P. carotovorum subsp. carotovorum. Since the PR1 gene was strongly induced and NPR1 and NPR4 were induced weakly in transgenic plants compared to the wild type, salicylic acid-dependent pathways is likely involved in the resistance to the soft rot pathogen P. carotovorum subsp. carotovorum in ExpI transgenic plants.

Fluoxetine Treatment during In Vitro Fertilization and Culture Increases Bovine Embryonic Development

  • Choe, Changyong;Kang, Dawon
    • Journal of Embryo Transfer
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    • v.29 no.2
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    • pp.133-139
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    • 2014
  • $K^+$ channels are involved in the regulation of a variety of physiological functions, including proliferation, apoptosis and differentiation, in mammalian cells. Our previous study demonstrated that the blockage of $K^+$ channels inhibits mouse early embryonic development. This study was designed to identify the effect of $K^+$ channels during bovine embryonic development. $K^+$ channel blockers (tetraethylammonium (TEA), $BaCl_2$, quinine, ruthenium red and fluoxetine) were added to the culture medium during in vitro fertilization (IVF) for 6 h to first identify the short-term effect of these chemicals. Among $K^+$ channel blockers, fluoxetine, which is used as a selective serotonin reuptake inhibitor, significantly increased the blastocyst formation rate by approximately 6% when compared to control. During the in vitro maturation (IVM) of immature oocytes and the in vitro culture (IVC) of embryos, the oocytes and embryos were exposed to fluoxetine for either a short-term (6 h) or a long-term (24 h) to compare the embryonic development in response to exposure time. The 6 h exposure to fluoxetine during IVM did not affect the blastocyst formation rate, but the rate of blastocyst formation was reduced after the 24 h exposure. On the other hand, embryonic development increased approximately 10% in both groups of embryos exposed to fluoxetine for 6 and 24 h during IVC. Taken together, fluoxetine treatment during IVF and IVC, but not IVM, enhances bovine embryonic development. These results suggest that fluoxetine-modulated signals in oocytes and embryos could be an important factor towards enhancing bovine embryonic development.

Calculation of Carbon Dioxide Emissions by South Korea's Fishery Industry (한국 수산업분야 어업용 연소연료의 사용실태와 CO2 배출량의 산정)

  • Lee, Dong-Woo;Lee, Jae-Bong;Kim, Yeong-Hye;Jung, Suk-Geun;Lee, Hae-Won;Hong, Byung-Kyu;Son, Myong-Ho
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.43 no.1
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    • pp.78-82
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    • 2010
  • Vessel numbers and fuel consumption by South Korea's offshore and coastal fisheries have continuously declined since 2000. Using the 2006 Intergovernmental Panel on Climate Change Guidelines, $CO_2$ emissions by South Korea's fishery industry (fishing and aquaculture, excluding deep-sea fishing) were calculated by the default $ CO_2$ emission factor and fuel consumption by fuel type, Emission of $CO_2$ was estimated to be 3.22 million $tCO_2$/year in 2007 for fisheries (excluding deep-sea fishing); when including deep-sea fishing, the estimated value increased to 4.11 million $tCO_2$/year. Fuel consumption per tonne of fishery production was 498 L, and the amount of $CO_2$ emission per tonne of production was 1.62 $tCO_2$. To calculate $CO_2$ emission more exactly, we must develop a system to compile energy balance statistics and introduce life-cycle assessment for the fishery industry.

Stage-specific Expression of Lanosterol 14${\alpha}$-Demethylase in Mouse Oocytes in Relation to Fertilization and Embryo Development Competence

  • Song, Xiaoming;Ouyang, Hong;Tai, Ping;Chen, Xiufen;Xu, Baoshan;Yan, Jun;Xia, Guoliang;Zhang, Meijia
    • Asian-Australasian Journal of Animal Sciences
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    • v.22 no.3
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    • pp.319-327
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    • 2009
  • Follicular fluid meiosis-activating sterol (FF-MAS) has been suggested as a positive factor which could improve the oocyte quality and subsequent embryo development after in vitro fertilization. However, FF-MAS is a highly lipophilic substance and is hard to detect in studying the relationship between MAS and quality of oocyte maturation. The present study focused on the expression of lanosterol 14${\alpha}$-demethylase (LDM), a key enzyme that converts lanosterol to FF-MAS, on mouse oocyte maturation and its potency on development. LDM expression was strong in gonadotropin-primed germinal vesicle stage oocytes, weak after germinal vesicle breakdown (GVBD), and then strong in MII stage oocytes. The LDM-specific inhibitor azalanstat significantly inhibited oocyte fertilization (from 79.4% to 68.3%, p<0.05). Also, azalanstat (5 to 50 ${\mu}M$) decreased the percentage of blastocyst development dosedependently (from 78.7% to 23.4%, p<0.05). The specific inhibition of sterol ${\Delta}14$-reductase and ${\Delta}7$-reductase by AY9944 accumulates FF-MAS and could increase blastocyst development rates. Additionally, in the AY9944 group, the rate of inner cell mass (ICM)/ total cells was similar to that of in vivo development, but the rate was significantly decreased in azalanstat treatment. In conclusion, LDM, the key enzyme of FF-MAS production, may play an important role in fertilization and early development of the mouse embryo, especially in vitro.