• 한국토양비료학회지
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• 제47권2호
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• pp.80-84
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• 2014

Phosphorus (P) is an essential nutrient for all living organisms. P is mostly obtained from mined rock phosphate. However, existing rock phosphate reserves could be exhausted in the next 50-100 years. As Korea is totally dependent on imported rock phosphate, we should seek for solution to overcome the P depletion by efficient use and recycling. For this, this study suggested a P flow model to identify the location and flow route of P in urban area based on traditional material flow analysis. The type of P entering the urban areas are fertilizer, food and feed. Each type of P is used in agriculture, human consumption and animal husbandry. After going through each process, P is moved to waste management facilities within food waste, excreta and sewage. Some portion of P in waste are buried, incinerated and discharged, which can be reservoir of P in the future.

• Nuclear Engineering and Technology
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• 제55권11호
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• pp.4228-4237
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• 2023

The Improved Deterministic Truncation of Monte Carlo (iDTMC) is a powerful acceleration and variance reduction scheme in the Monte Carlo analysis. The concept of the iDTMC method and correlated sampling-based real variance estimation are briefly introduced. Moreover, the application of the iterative scheme to the correlated sampling is discussed. The iDTMC method is utilized in a 3-dimensional small modular reactor (SMR) model problem. The real variances of burnup-dependent criticality and power distribution are evaluated and compared with the ones obtained from 30 independent iDTMC calculations. The impact of the inactive cycles on the correlated sampling is also evaluated to investigate the consistency of the correlated sample scheme. In addition, numerical performances and sensitivity analysis on the real variance estimation are performed in view of the figure of merit of the iDTMC method. The numerical results show that the correlated sampling accurately estimates the real variances with high computational efficiencies.

• 한국원자력학회:학술대회논문집
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• 한국원자력학회 2001년도 춘계학술발표회요약집
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• pp.60.1-60
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• 2001

• 대한전자공학회논문지SD
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• 제46권12호
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• pp.10-17
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• 2009

Double-Gate MOSFET 구조를 사용한 Nano-Electro-Mechanical MOSFET (NEMFET)는 게이트 길이가 짧아지면서 나타나는 단채널 현상을 효과적으로 제어하는 새로운 구조의 차세대 소자이다. 특히 공핍형 Double-gate NEMFET (Dep-DGNEMFET)은 차단 상태에서 얇은 산화막을 가지므로 subthreshold 전류가 효과적으로 제어된다. 이러한 Dep-DGNEMFET 특성에 대한 해석적 수식을 유도하고 소자 구조가 변화하는 경우의 특성 변화를 분석하였다. 또한 ITRS (International Technology Roadmap for Semiconductors) 전류 기준값을 만족시키기 위하여 Dep-DGNEMFET 소자 구조를 최적화 하였다.

• Mass Spectrometry Letters
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• 제9권2호
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• pp.51-55
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• 2018

Capture of non-glycoproteins during lectin affinity chromatography is frequently observed, although it would seem to be anomalous. In actuality, lectin affinity chromatography works at post-translational modification (PTM) sites on a glycoprotein which is not involved in protein-protein interactions (PPIs). In this study, serial affinity column set (SACS) using lectins followed by proteomics methods was used to identify PPI mechanisms of captured proteins in human plasma. MetaCore, STRING, Ingenuity Pathway Analysis (IPA), and IntAct were individually used to elucidate the interactions of the identified abundant proteins and to obtain the corresponding interaction maps. The abundant non-glycoproteins were captured with the binding to the selected glycoproteins. Therefore, depletion process in sample pretreatment for abundant protein removal should be considered with more caution because it may lose precious disease-related low abundant proteins through PPIs of the removed abundant proteins in human plasma during the depletion process in biomarker discovery. Glycoproteins bearing specific glycans are frequently associated with cancer and can be specifically isolated by lectin affinity chromatography. Therefore, SACS using Lycopersicon esculentum lectin (LEL) can also be used to study disease interactomes.

• Nuclear Engineering and Technology
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• 제52권11호
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• pp.2431-2441
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• 2020

Currently, the pin-by-pin homogenized solvers are a very active research field as they can, unlike the nodal codes, directly predict the local power, while requiring significantly less computational resources than the heterogeneous transport codes. This paper presents a recently developed pin-by-pin diffusion/SP3 solver Tortin, its spatial discretization method and the reflector treatment. Regarding the spatial discretization, it was observed that the finite difference method applied on pin-cell size mesh does not properly capture the big flux change between MOX and uranium fuel, while the nodal expansion method is more accurate but too slow. If the finite difference method is used with a finer mesh in the outer two pin rows of the fuel assembly, it increases the required computation time by only 50%, but decreases the pin power errors below 1% with respect to lattice code reference solutions. The paper further describes the coupling of Tortin with a microscopic depletion solver. Several verification tests show that the SP3 pin-by-pin solver can reproduce the heterogeneous transport solvers results with very good accuracy, even for fuel cycle depletion of very heterogeneous core employing MOX fuel or inserted control rods, while being two orders of magnitude faster.

• 한국방사성폐기물학회:학술대회논문집
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• 한국방사성폐기물학회 2018년도 추계학술논문요약집
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• pp.91-92
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• 2018

• 지질공학
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• 제29권4호
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• pp.439-449
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• 2019

하천 건천화 예방 및 하천수와 지하수의 효율적 연계 이용을 위해서는 지하수 이용이 하천의 수량에 미치는 영향 평가가 수반되어야 한다. 이를 위해서는 대수층과 하천의 다양한 수리특성 조건에 대해 지하수 양수에 따른 하천수량의 변화 분석이 필요하다. 본 연구에서는 하천수위 변동을 반영할 수 있고 지하수 양수에 따른 하천수 감소량을 산정할 수 있는 Baalousha 해석해를 이용하여 하천수위가 지수함수적으로 감소하는 경우와, 감소 후 다시 회복되는 경우에 대해 지하수 양수로 인한 하천수 감소량의 변화 특성을 분석하였다. 대수층의 수리특성으로 투수량계수 10~100 ㎡/d 및 저류계수 0.05~0.3, 하천의 수리특성으로 하상수리전도성 0.01~20 m/d, 하천수위 감수상수 0.1~1.0 1/d, 그리고 하천과 관정의 이격거리 100~500 m 조건에 대해 지하수 양수량 대비 하천수 감소량인 하천수 기여도를 산정하고 그 거동 특성을 하천수위 변동 유무에 따라 종합적으로 분석, 제시하였다. 하천수위 감소 영향을 고려하였을 경우 하천수 기여도가 크게 감소하고 하천-관정 이격거리와 수리확산도의 함수인 하천고갈인자 값에 영향을 작게 받는 것으로 나타났으며, 반면에 하천수위 감소 후 회복되는 조건에서의 하천수 기여도는 하천수위 변동이 없는 경우와 큰 차이가 없는 것으로 나타났다. 이러한 결과는 하천수위 조절을 통해 지하수 양수시 하천수 및 대수층 저류량에 미치는 상대적 영향의 통제가 가능함을 의미한다.

• Environmental Analysis Health and Toxicology
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• 제19권4호
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• pp.359-366
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• 2004

Iron (Fe) is an essential metal in biological processes, which maintains a homeostasis in the human body. Divalent metal transporter 1 (DMT1) has been known as an iron transporting membrane protein, which is involved in the uptake Fe at the apical portion of intestinal epithelium, and may transport Fe across the membrane of acidified endosome in peripheral tissues. In this study, we studied the tissue distribution of DMT1 in the Fe supplemented (FeS) diet fed rats, and the regulation of DMT1 expression by depleting body Fe. Sprague-Dawley rats were divided into two groups, and fed FeS (120 mg Fe/kg) diet or Fe deficient (FeD, 2∼6 mg Fe/kg) diet for 4 weeks. The evaluation of body Fe status was monitored by measuring sFe, UIBC and tissue Fe concentration. Additionally, DMT1 mRNA levels were analyzed in the peripheral tissues by using the quantitative real time RT-PCR method. In the FeS diet fed rats, the tissue Fe was maintained at a relatively high level, and DMT1 was eventually expressed in all tissues studied. DMT1 was highly expressed in the testis, kidney and spleen, while a moderate levels of DMT1 expression was detected in the brain, liver and heart. In the digestive system, the highest level of DMT1 was found in the duodenum. Feeding the FeD diet caused a reduced body weight gain and depletion of body Fe with finding of decreased sFe, increased UIBC and decreased tissue Fe concentration. The depletion of body Fe upregulated DMT1 expression in the peripheral tissue. The expression of DMT1 was very sensitive to the body Fe depletion in the small intestine, especially in the duodenum, showing dramatically higher levels in the FeD rats than those of the FeS group. In the FeD diet fed animals, the expression of DMT1 was low significantly in other tissues compared with the duodenum. The expression of DMT1, however, was 60∼120% higher in the testis, kidney and spleen, and 30∼50% higher in the lung, liver and heart, compared to the FeS diet fed rats. In summary, DMT1 expression was ubiquitous in mammalian tissue, and the level of expression was the organ-dependent. The expression of DMT1 in peripheral tissues was upregulated by depletion of body Fe. Duodenum was the most sensitive tissue among organs studied during Fe depletion, and expressed the greatest level of DMT1, while other tissues were less higher than in duodenum. This study supports that DMT1 plays a role in maintaining the body Fe level through intestinal uptake as well as homeostasis of Fe in the peripheral tissue.

• Environmental Analysis Health and Toxicology
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• 제11권3_4호
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• pp.53-57
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• 1996

In this study we investigated the effect of hydroxybrazilin on glutathione depletion induced by BrCCl$_3$ and menadione in cultured hepatocytes to understand the cellular mechanisms of hepatoprotective effect of hydroxybrazilin. Hydroxybrazilin alone had no effect on total glutathione level and the ratio of reduced glutathione/total glutathione (GSH/(GSSG+GSH)). BrCCl$_3$ dramatically decreased total glutathione level and hydroxybrazilin significantly prevented glutathion depletion by BrCCl$_3$. The ratio of GSH/(GSSG+ GSH) was also decreased by BrCCl$_3$ and recovered by hydroxybrazilin treatment. Menadione decreased total glutathione level and the ratio of GSH/(GSSG+GSH) but hydroxybrazilin showed no significant effects on menadione-induced glutathione depletion. These data suggest that hydroxybrazilin might prevent the hepatotoxicity induced by chemicalderived radicals but not the toxicity linked with oxidative stress.