• Korean Journal of Soil Science and Fertilizer
• /
• v.47 no.2
• /
• pp.80-84
• /
• 2014

Phosphorus (P) is an essential nutrient for all living organisms. P is mostly obtained from mined rock phosphate. However, existing rock phosphate reserves could be exhausted in the next 50-100 years. As Korea is totally dependent on imported rock phosphate, we should seek for solution to overcome the P depletion by efficient use and recycling. For this, this study suggested a P flow model to identify the location and flow route of P in urban area based on traditional material flow analysis. The type of P entering the urban areas are fertilizer, food and feed. Each type of P is used in agriculture, human consumption and animal husbandry. After going through each process, P is moved to waste management facilities within food waste, excreta and sewage. Some portion of P in waste are buried, incinerated and discharged, which can be reservoir of P in the future.

• Nuclear Engineering and Technology
• /
• v.55 no.11
• /
• pp.4228-4237
• /
• 2023

The Improved Deterministic Truncation of Monte Carlo (iDTMC) is a powerful acceleration and variance reduction scheme in the Monte Carlo analysis. The concept of the iDTMC method and correlated sampling-based real variance estimation are briefly introduced. Moreover, the application of the iterative scheme to the correlated sampling is discussed. The iDTMC method is utilized in a 3-dimensional small modular reactor (SMR) model problem. The real variances of burnup-dependent criticality and power distribution are evaluated and compared with the ones obtained from 30 independent iDTMC calculations. The impact of the inactive cycles on the correlated sampling is also evaluated to investigate the consistency of the correlated sample scheme. In addition, numerical performances and sensitivity analysis on the real variance estimation are performed in view of the figure of merit of the iDTMC method. The numerical results show that the correlated sampling accurately estimates the real variances with high computational efficiencies.

• Proceedings of the Korean Nuclear Society Conference
• /
• 2001.05a
• /
• pp.60.1-60
• /
• 2001

• Journal of the Institute of Electronics Engineers of Korea SD
• /
• v.46 no.12
• /
• pp.10-17
• /
• 2009

Nano-Electro-Mechanical MOSFET (NEMFET) using Double-Gate MOSFET (DGMOS) structure can efficiently control the short channel effect. Espatially, subthreshold current of depletion-mode Double-Gate NEMFET (Dep-DGNEMFET) decreases in the off-state due to the thin equivalent-oxide thickness. Analytical $t_gap$ vs. $V_g$ equation for Dep-DGNEMFET is derived and characteristics for different device structures are analyzed. Dep-DGNEMFET structure is optimized to satisfy ITRS criteria.

• Mass Spectrometry Letters
• /
• v.9 no.2
• /
• pp.51-55
• /
• 2018

Capture of non-glycoproteins during lectin affinity chromatography is frequently observed, although it would seem to be anomalous. In actuality, lectin affinity chromatography works at post-translational modification (PTM) sites on a glycoprotein which is not involved in protein-protein interactions (PPIs). In this study, serial affinity column set (SACS) using lectins followed by proteomics methods was used to identify PPI mechanisms of captured proteins in human plasma. MetaCore, STRING, Ingenuity Pathway Analysis (IPA), and IntAct were individually used to elucidate the interactions of the identified abundant proteins and to obtain the corresponding interaction maps. The abundant non-glycoproteins were captured with the binding to the selected glycoproteins. Therefore, depletion process in sample pretreatment for abundant protein removal should be considered with more caution because it may lose precious disease-related low abundant proteins through PPIs of the removed abundant proteins in human plasma during the depletion process in biomarker discovery. Glycoproteins bearing specific glycans are frequently associated with cancer and can be specifically isolated by lectin affinity chromatography. Therefore, SACS using Lycopersicon esculentum lectin (LEL) can also be used to study disease interactomes.

• Nuclear Engineering and Technology
• /
• v.52 no.11
• /
• pp.2431-2441
• /
• 2020

Currently, the pin-by-pin homogenized solvers are a very active research field as they can, unlike the nodal codes, directly predict the local power, while requiring significantly less computational resources than the heterogeneous transport codes. This paper presents a recently developed pin-by-pin diffusion/SP3 solver Tortin, its spatial discretization method and the reflector treatment. Regarding the spatial discretization, it was observed that the finite difference method applied on pin-cell size mesh does not properly capture the big flux change between MOX and uranium fuel, while the nodal expansion method is more accurate but too slow. If the finite difference method is used with a finer mesh in the outer two pin rows of the fuel assembly, it increases the required computation time by only 50%, but decreases the pin power errors below 1% with respect to lattice code reference solutions. The paper further describes the coupling of Tortin with a microscopic depletion solver. Several verification tests show that the SP3 pin-by-pin solver can reproduce the heterogeneous transport solvers results with very good accuracy, even for fuel cycle depletion of very heterogeneous core employing MOX fuel or inserted control rods, while being two orders of magnitude faster.

• Proceedings of the Korean Radioactive Waste Society Conference
• /
• 2018.11a
• /
• pp.91-92
• /
• 2018

• The Journal of Engineering Geology
• /
• v.29 no.4
• /
• pp.439-449
• /
• 2019

To prevent the drying-out of streams and to make effective use of stream water and groundwater, it is necessary to evaluate the impact of groundwater pumping on nearby streams. To this end, stream depletion due to groundwater pumping should be investigated in terms of various hydraulic characteristics of the aquifer and stream. This study used the Baalousha analytical solution, which accounts for stream-stage variation over time, to analyze stream depletion due to groundwater pumping for cases where the stream level decreases exponentially and recovers after the decrease. For conditions such as an aquifer transmissivity of 10~100 ㎡ d^-1, storage coefficient 0.05~0.3, streambed hydraulic conductance 0.1~1.0 m d^-1, stream-well distance 100~500 m, and stage recession coefficient 0.1~1.0 d^-1, the contribution of stream water (the dimensionless ratio of stream water reduction rate to groundwater pumping rate) was analyzed in cases where stream level change was considered. Considering the effect of stream-stage recession, the contribution of stream water is greatly reduced and is less affected by the stream-depletion factor, which is a function of the stream-to-well distance and hydraulic diffusivity. However, there is no significant difference in stream depletion under constant- and variable-stage recovery after recession. These results indicate that stream level control can distribute the relative impacts on stream water and aquifer storage during groundwater pumping

• Environmental Analysis Health and Toxicology
• /
• v.19 no.4
• /
• pp.359-366
• /
• 2004

Iron (Fe) is an essential metal in biological processes, which maintains a homeostasis in the human body. Divalent metal transporter 1 (DMT1) has been known as an iron transporting membrane protein, which is involved in the uptake Fe at the apical portion of intestinal epithelium, and may transport Fe across the membrane of acidified endosome in peripheral tissues. In this study, we studied the tissue distribution of DMT1 in the Fe supplemented (FeS) diet fed rats, and the regulation of DMT1 expression by depleting body Fe. Sprague-Dawley rats were divided into two groups, and fed FeS (120 mg Fe/kg) diet or Fe deficient (FeD, 2∼6 mg Fe/kg) diet for 4 weeks. The evaluation of body Fe status was monitored by measuring sFe, UIBC and tissue Fe concentration. Additionally, DMT1 mRNA levels were analyzed in the peripheral tissues by using the quantitative real time RT-PCR method. In the FeS diet fed rats, the tissue Fe was maintained at a relatively high level, and DMT1 was eventually expressed in all tissues studied. DMT1 was highly expressed in the testis, kidney and spleen, while a moderate levels of DMT1 expression was detected in the brain, liver and heart. In the digestive system, the highest level of DMT1 was found in the duodenum. Feeding the FeD diet caused a reduced body weight gain and depletion of body Fe with finding of decreased sFe, increased UIBC and decreased tissue Fe concentration. The depletion of body Fe upregulated DMT1 expression in the peripheral tissue. The expression of DMT1 was very sensitive to the body Fe depletion in the small intestine, especially in the duodenum, showing dramatically higher levels in the FeD rats than those of the FeS group. In the FeD diet fed animals, the expression of DMT1 was low significantly in other tissues compared with the duodenum. The expression of DMT1, however, was 60∼120% higher in the testis, kidney and spleen, and 30∼50% higher in the lung, liver and heart, compared to the FeS diet fed rats. In summary, DMT1 expression was ubiquitous in mammalian tissue, and the level of expression was the organ-dependent. The expression of DMT1 in peripheral tissues was upregulated by depletion of body Fe. Duodenum was the most sensitive tissue among organs studied during Fe depletion, and expressed the greatest level of DMT1, while other tissues were less higher than in duodenum. This study supports that DMT1 plays a role in maintaining the body Fe level through intestinal uptake as well as homeostasis of Fe in the peripheral tissue.

• Environmental Analysis Health and Toxicology
• /
• v.11 no.3_4
• /
• pp.53-57
• /
• 1996

In this study we investigated the effect of hydroxybrazilin on glutathione depletion induced by BrCCl$_3$ and menadione in cultured hepatocytes to understand the cellular mechanisms of hepatoprotective effect of hydroxybrazilin. Hydroxybrazilin alone had no effect on total glutathione level and the ratio of reduced glutathione/total glutathione (GSH/(GSSG+GSH)). BrCCl$_3$ dramatically decreased total glutathione level and hydroxybrazilin significantly prevented glutathion depletion by BrCCl$_3$. The ratio of GSH/(GSSG+ GSH) was also decreased by BrCCl$_3$ and recovered by hydroxybrazilin treatment. Menadione decreased total glutathione level and the ratio of GSH/(GSSG+GSH) but hydroxybrazilin showed no significant effects on menadione-induced glutathione depletion. These data suggest that hydroxybrazilin might prevent the hepatotoxicity induced by chemicalderived radicals but not the toxicity linked with oxidative stress.