• Proceedings of the KIEE Conference
• /
• 2009.07a
• /
• pp.1234_1235
• /
• 2009

The Langmuir-Blodgett (LB) method has been one of the most suitable techniques for fabricating organic thin films with well-controlled structures, compositions and thickness at the molecular level. We investigated the surface activity of dendrimer films at air-water interface by $\pi$-A isotherm. Also, we attempted to fabricate a G3-9Ph dendritic silsequioxane LB films. And their surface morphologies were observed by atomic force microscopy (AFM).

• Proceedings of the PSK Conference
• /
• 2002.10a
• /
• pp.306.3-307
• /
• 2002

According to recent studies. cefodizime. a third generation cephalosporin antibiotic agent. may potentially have the capability of stimulating chemotactic activity of neutrophils and monocytes as well as the strong immuno-modulator. We have studied to see if cefodizime can be a potential substance inducing an Immunological activities on immune cells. such as dendritic cells and macrophages. In experimental process. dendritic cell and macrophage were taken from mice and mixed with 10${\mu}\ell$/$m\ell$. 50$${\mu}\ell$/$m\ell$, 100${\mu}\ell$/$m\ell$.cefodizime and 1$${\mu}\ell$/$m\ell$ IFN-${\gamma} 10U/$m\ell$＋LPS. (omitted)

• Journal of the Korean Crystal Growth and Crystal Technology
• /
• v.4 no.3
• /
• pp.276-283
• /
• 1994

The dislocation configuration in web-grown silicon ribbon was investigated using chemical etching techniques. The presence of dislocation loops on twin planes is observed and acounted for by self-interstitial condensation. The interstitials were either quenched in, due to the rapid cooling of the ribbon from the solidification temperatures, or produced by oxide precipitation on the twin plane. Very large faulted loops of mm size were also observed.

• CELLMED
• /
• v.3 no.1
• /
• pp.3.1-3.3
• /
• 2013

The receptor activator of NF-${\kappa}B$ ligand (RANKL), a member of the tumor necrosis factor ligand family, has extensive functions beyond osteoclast development. RANKL is expressed in many immune cells such as osteoblasts, osteocytes, marrow stromal cells, activated T cells, synovial cells, keratinocytes, and mammary gland epithelial cells as well as in various tissues. The ligation of RANK by RANKL promotes dendritic cells (DCs) survival through prosurvival signals and the up-regulation of the anti-apoptotic proteins Bcl-2 and Bcl-$x_L$ and plays a crucial role in DCs-mediated Th1 differentiation. Therefore, RANKL plays an important role in the regulation of DCs/T cells-mediated specific immunity. This review will briefly inform our current understanding of the role of RANKL signaling in T cells-DCs communication in the immune system.

• BMB Reports
• /
• v.43 no.3
• /
• pp.188-192
• /
• 2010

Inflammatory reactology has become increasingly important in diabetic kidney disease. In this study, we estabilished STZ-induced diabetic rat model to investigate whether dendritic cells (DCs) mediated tubulointerstitial damages, and whether the effects by DCs were mediated by P-selectin expression and can be inhibited by atorvastatin. The study demonstrated that there was an accumulation of DCs in diabetic rats mediated by P-selectin. It also showed the accumulation of DCs and expression of P-selectin was closely correlated with the degree of renal tubulointerstitial injury. These effects were markedly attenuated by atorvastatin. Thus, DCs play a role in tubulointerstitial damages, atorvasttin can prevent renal tubulointerstitium from damage by inhibiting the P-selectin expression and DCs migration.

• Proceedings of the Korean Vacuum Society Conference
• /
• 2014.02a
• /
• pp.132.1-132.1
• /
• 2014

Fluorescent-magnetic nanoclusters were synthesized for biomedical applications. The nanoclusters consisted of superparamagnetic core-nanoclusters, highly fluorescent shell of nanocrystals, and lipid A. Magnetic cores were used for both magnetic resonance imaging (MRI) and cell separation. Fluorescent shell was used for optical imaging. The lipid-A-loaded nanoclusters were up-taken by dendritic cells via phagocytosis, which successfully activated dendritic cells. The dendritic cells were migrated to lymph nodes and spleen of mice. The results showed that our novel nanoclusters can play a role as an efficient optical and magnetic imaging, a cell separating and a pathogen mimetic agent at the same time. Additionally, synthesis of wavelength conversion nanowires will be discussed, which may be used as an optical nanoprobe in biological studies.

• Macromolecular Research
• /
• v.10 no.3
• /
• pp.178-180
• /
• 2002

The conducting behavior of dendritic carbosilanes including palladium ions (Pd$^{2+}$) has been measured. The palladium ion containing dendrimers were prepared by the addition of palladium dichloride to double-layered dendritic carbosilanes, which consist of phenylethynyl groups (-C≡CPh) on the outmost periphery as well as phenylethenyl and propyleneoxy groups (-CH=CPh- and (CH$_2$)$_3$O-) in the inner shell. By measuring conductivities, palladium ion containing dendrimers revealed an increasing tendency according to the increasing number of double bonds in the inner shells of dendritic carbosilanes.s.

• Journal of Korea Foundry Society
• /
• v.37 no.4
• /
• pp.108-114
• /
• 2017

In this study, we investigated the effect of the Si content on the secondary dendrite arm spacing (SDAS) of hypoeutectic Al-Si binary alloys in the range of 4~10 wt% Si. Cooling curves were measured during the solidification of the alloy cast in a step-wise mold. We compared two kinds of solidification time: the first is the total solidification time for both dendritic and eutectic growth, and the second is the solidification time for only dendritic growth. The proportional constant in the relationship between SDAS and cooling rate was estimated, as this constant represents the stability of the cast microstructure. The proportional constant decreased with the Si contents from 4 wt% to 8 wt%, and it remains relatively uniform with up to 10 wt% of Si.

• IMMUNE NETWORK
• /
• v.15 no.1
• /
• pp.1-8
• /
• 2015

Innate immune cells survey antigenic materials beneath our body surfaces and provide a front-line response to internal and external danger signals. Dendritic cells (DCs), a subset of innate immune cells, are critical sentinels that perform multiple roles in immune responses, from acting as principal modulators to priming an adaptive immune response through antigen-specific signaling. In the gut, DCs meet exogenous, non-harmful food antigens as well as vast commensal microbes under steady-state conditions. In other instances, they must combat pathogenic microbes to prevent infections. In this review, we focus on the function of intestinal DCs in maintaining intestinal immune homeostasis. Specifically, we describe how intestinal DCs affect IgA production from B cells and influence the generation of unique subsets of T cell.

• Bulletin of the Korean Chemical Society
• /
• v.32 no.10
• /
• pp.3624-3628
• /
• 2011

Fr$\acute{e}$chet-type dendritic benzaldehydes were efficiently synthesized using 3,5-dihydroxybenzaldehyde as an aldehyde focal point functionalized unit by adding a generation to the existing dendron or direct oxidation of Fr$\acute{e}$chet-type dendritic benzyl alcohols. These dendritic benzaldehydes were applied for the construction of dendrimers containing secondary amines as connectors via Staudinger/aza-Wittig Reactions with ${\alpha}$,${\alpha}'$,-diazidop-xylene core.