• 이베로아메리카
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• 제14권1호
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• pp.111-142
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• 2012

Rodolfo Walsh es historiador de su propio tiempo, protagonista y testigo que escribió para dar testimonio. Sus obras pertenecen a un instante, a la historia. El escritor habla en nombre de la verdad y denuncia los manejos del poder. El trata de desmontar y hacer la crítica de la escritura oficial y sus medios, lo que trae como consecuencia el develamiento del funcionamiento del aparato de Estado en América Latina. Sus obras que marcan la historia trágica de Argentina tienen un alto nivel de calidad. Para él la ficción es el arte de la elipsis y trabaja con la alusión, y su construcción es antagónica con la estética urgente del compromiso y las simplificaciones del realismo social. Este trabajo tiene como objeto investigar las estrategias narrativas de Rodolfo Walsh a través de las tres obras principales (Operación Masacre, ¿Quién mató a Rosendo?, Esa mujer), y revelar la visión del mundo que nos muestra. Al fin podremos saber la estructura significativa representada en sus obras.

• BMB Reports
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• 제37권3호
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• pp.320-334
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• 2004

StMBF1 (Solanum tuberosum multiprotein bridging factor 1) is a plant member of the MBF1 family of transcriptional co-activators. In an attempt to understand the role of StMBF1, we analyzed its interaction with plant transcription factors of the homeodomain-leucine zipper (Hd-Zip) family, a group of proteins with a typical leucine zipper motif adjacent to a homeodomain. StMBF1 is able to interact in vitro with the Hd-Zip protein Hahb-4 both in the presence and absence of DNA. Upon binding, StMBF1 increases the DNA binding affinity of Hahb-4, and of another plant homeodomain containing protein from the GL2/Hd-Zip IV family, HAHR-1. The biological role of interactions is discussed in this paper.

• 대한수학회지
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• 제61권5호
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• pp.837-851
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• 2024

We classify toric log del Pezzo surfaces of Picard number one by introducing the notion, cascades. As an application, we show that if such a surface admits a Kähler-Einstein metric, then it should admit a special cascade and it satisfies the equality of the orbifold Bogomolov-Miyaoka-Yau inequality, i.e., K² = 3e_orb. Moreover, we provide an algorithm to compute a toric log del Pezzo surfaces of Picard number one for a given input of singularity types.

• IMMUNE NETWORK
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• 제9권5호
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• pp.153-157
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• 2009

The leukocyte adhesion to endothelium is pivotal in leukocyte recruitment which takes place during inflammatory, autoimmune and infectious conditions. The interaction between leukocytes and endothelium requires an array of adhesion molecules expressed on leukocytes and endothelial cells, thereby promoting leukocyte recruitment into sites of inflammation and tissue injury. Intervention with the adhesion molecules provides a platform for development of anti-inflammatory therapeutics. This review will focus on developmental endothelial locus-1 (Del-1), an endogenous inhibitor of leukocyte adhesion.

• Asian Pacific Journal of Cancer Prevention
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• 제15권5호
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• pp.1931-1936
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• 2014

Background: Gastric cancer (GC) ranks as one of the major causes of mortality due to cancer worldwide. In Chile, it is currently the leading cause of cancer death. Identification of novel molecular markers that may help to improve disease diagnosis at early stages is imperative. Materials and Methods: Using whole-genome DNA microarrays we determined differential mRNA levels in fresh human GC samples compared to adjacent healthy mucosa from the same patients. Genes significantly overexpressed in GC were validated by RT-PCR in a group of 14 GC cases. Results: The genes CD248, NSD1, RAB17, ABCG8, Ephb1 and P2RY2 were detected as the top overexpressed in GC biopsies. P2RY2, Ephb1 and CD248 showed the best sensitivity for GC detection with values of 92.9%, 85.7% and 64.3% (p<0.05), respectively. Specificity was 85.7%, 71.4% and 71.4% (p<0.05), for each respectively.

• East Asian mathematical journal
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• 제38권3호
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• pp.321-329
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• 2022

For an ample divisor A of birational type on a singular del Pezzo surface S of degree 4 with A₁-singularity, we show that the affine cone of S defined by A is flexible

• Journal of Plant Biotechnology
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• 제45권3호
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• pp.228-235
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• 2018

In this study, two pepper varieties, PRH1 (powdery mildew resistance line) and Saengryeg (powdery mildew resistance line), were resequenced using next generation sequencing technology in order to develop InDel markers. The genome-wide discovery of InDel variation was performed by comparing the whole-genome resequencing data of two pepper varieties to the Capsicum annuum cv. CM334 reference genome. A total of 334,236 and 318,256 InDels were identified in PRH1 and Saengryeg, respectively. The greatest number of homozygous InDels were discovered on chromosome 1 in PRH1 (24,954) and on chromosome 10 (29,552) in Saengryeg. Among these homozygous InDels, 19,094 and 4,885 InDels were distributed in the genic regions of PRH1 and Saengryeg, respectively, and 198,570 and 183,468 InDels were distributed in the intergenic regions. We have identified 197,821 polymorphic InDels between PRH1 and Saengryeg. A total of 11,697 primers sets were generated, resulting in the discovery of four polymorphic InDel markers. These new markers will be utilized in order to identify disease resistance genotypes in breeding populations. Therefore, our results will make a one-step advancement in whole genome resequencing and add genetic resource datasets in pepper breeding research.

• International Journal of Oral Biology
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• 제34권1호
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• pp.21-28
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• 2009

Mutations in DLX3 are associated with both autosomal dominant hypoplastic hypomaturation amelogenesis imperfecta (ADHHAI) and tricho-dento-osseous (TDO) syndrome. ADHHAI is caused by a c.561_562delCT (2bp-del DLX3) mutation whereas TDO syndrome is associated with a c.571_574delGGGG (4bp-del DLX3) mutation. However, although the causal relationships between DLX3 and an enamel phenotype have been established, the pathophysiological role of DLX3 mutations in enamel development has not yet been clarified. In our current study, we prepared expression vectors for wild type and deletion mutant DLX3 products (4bp-del DLX3, 2bp-del DLX3) and examined the effects of their overexpression on the expression of the enamel matrix proteins and proteases. Wild type DLX3 enhanced the expression of matrix metalloprotease 20 (MMP20) mRNA and protein in murine ameloblast-like cells. However, neither a 4bp-del nor 2bp-del DLX3 increased MMP20 expression. Wild type DLX3, but not the above DLX3 mutants, also increased the activity of reporters containing 1.5 kb or 0.5 kb of the MMP20 promoter. An examination of protein stability showed that the half-life of wild type DLX3 protein was less than 12 h whilst that of both deletion mutants was longer than 24 h. Endogenous Dlx3 was also found to be continuously expressed during ameloblast differentiation. Since inactivating mutations in the gene encoding MMP20 are associated with amelogenesis imperfecta, the inability of 4bp-del or 2bp-del DLX3 to induce MMP20 expression suggests a possible involvement of such mutations in the enamel phenotype associated with TDO syndrome or ADHHAI.

• 한국인터넷방송통신학회논문지
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• 제19권3호
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• pp.53-58
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• 2019

본 논문은 전술 통신망에서 QoS 향상을 위한 클래스 기반의 FQ-CoDel(Flow queue-Control Delay) 알고리즘을 제안한다. 전술 통신망에서 다양한 응용체계 서비스를 제공하게 되면서 병목현상으로 인한 트래픽 손실 및 지연 문제가 대두되었고 따라서 효과적인 트래픽 처리 방안 연구에 대한 필요성이 제기되었다. 제안방안은 클래스 기반의 FQ-CoDel 알고리즘을 이용한 동적인 버퍼 관리 및 스케줄링 기술로써 서비스 특성 및 중요도에 따라 해당 큐에 패킷을 분류하고 주기적으로 각 패킷의 대기시간을 체크하여 기준 대기 시간을 초과하는 경우 해당 패킷을 폐기하여 큐에 저장된 트래픽 양을 일정 수준으로 조절한다.

• 이탈리아어문학
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• 제33호
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• pp.1-27
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• 2011

Questo studio ha lo scopo di configurare la gerarchia tematica del sintagma genitivale in italiano all'interno della struttura sintattica. Il sintagma genitivale composto dalla forma "sostantivo+di+sostantivo", può avere i significati di descrizione, origine, apposizione, parte, luogo, e anche può rappresentare la struttura argomentale come argomento esterno(caso soggettivo) o argomento interno(caso oggettivo) e può assegnare il ruolo tematico di agente, tema, esperiente, beneficario in relazione al rapporto con la testa nominale oltre ad avere il significato possesivo. Per quanto riguarda la realizzazione e il significato dell'argomento nel sintagma genitivale diverse che cambiano secondo il tipo della testa nominale, ho classificato i nomi deverbali come nomi monoargomentali, nomi biargomentali, nomi triargomentali sulla base di Renzi et al(1991). Inoltre avendo confermato che il marcatore del caso genitivale di deve esserci nel caso in cui obbligatoriamente la struttura del sintagma nominale composto dai vari livelli, come NP, FP e DP, proposti da Longobardi(2001) per spiegare la differenza semantica del sintagma genitivale con la struttura sintattica, ho cercato di individuare l'ordine degli argomenti, osservando l'ambiguità e il cambiamento del significato del sintagma genitivale nel sintagma nominale. Cioé la differenza della possibilità interpretativa è una cosa strutturale, quindi possibilmente si può configurare la semantica del sintagma genitivale nella struttura sintattica.