• 한국산업보건학회지
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• 제19권3호
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• pp.280-287
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• 2009

High-tech microelectronics industry is known as one of the most chemical-intensive industries. In Korea, Microelectronics industry occupied 38% of export and 16% of working employees work in microelectronics industry. But, chemical information and health hazards of high-tech microelectronics manufacturing are poorly understood because of rapid development and its penchant for secrecy. We need to investigate on chemical use and exposure control. We Site-visits to 6 high-tech microelectronics manufacturing company which have cleanroom work using over 1,000kg organic solvents (5 semi-conductor chips and its related parts company, 1 liquid crystal display (LCD)). We reviewed their data on chemical use and ventilation system, and measured TVOCs (Total Volatile Organic Compounds) and carbon dioxide concentration. All cleanroom air passed through hepa filters to acheive low particle levels and only 1 cleanroom uses carbon filters to minimize the organic solvents exposures In TVOC screening test, Cleanroom for semi-conductor chips and its related parts company with laminar down flow system (e.g. class 1~100) showed nondetectable level of TVOCs concentration, but Cleanroom for liquid crystal display (LCD) with conventional flow system (e.g. class 1,000~10,000) showed 327 ppm as TVOCs. Acetone concentration in cleanroom for Jig cleaning, LC Injection, Sealing processes were 18.488ppm (n=14), 49.762 ppm (n=15), 8.656 ppm (n=14) as arithmetric mean. Acetone concentration in cleanroom for LCD inspection process was 40ppm (n=55) as geometric mean, where the range was 7.8~128.7ppm and weakly correlated with ventilation rate efficiency(r=0.44, p<0.05). To control organic solvents in cleanrooms, chemical and carbon filters should be installed with hepa filters. Even though their volatile organic compounds concentration was not exceed to occupational exposure limits, considering of entrance limited cleanroom environment, long-term period exposure effects and adverse health effects of cleanroom worker need further reseach.

• 한국식품위생안전성학회지
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• 제14권3호
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• pp.265-269
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• 1999

마비성패류독은 매년 4월과 5월 초에 정점을 이루어서 국민보건을 위협하고 있고 수산물 수출에도 타격을 주고 있다. 현재 수출 주력 상품으로 국과 진주담치 통조림이 있는데 독력이 낮은 제품은 통조림 제조 과정에서 대부분의 독이 파괴되나 독력이 높은 원료로 제조한 통조림은 잔존독이 문제가 되고 있다. 그러므로 독화된 진주담치와 굴로 제조된 통조림을 상온에서 2년과 저장하면서 독력 변화를 측정하여 식품위생 대책을 세우는 데에 필요한 자료를 제공하고자 한다. 진주담치와 굴 통조림을 2년간 상온에서 저장한 결과 두 시료간의 독소 잔존력의 차이는 없었다. 보일드 통조림과 훈연기름담금 통조림은 2년후에 독소의 불활성화가 어느 정도 인정되었으나 초유지 통조림인 경우 2년 후에도 초기 독력을 유지하였다. 원료의 최초 독력이 높은 경우 제조된 통조림에 독소가 잔존하고 이들 독소를 장기 저장(2년)으로 제거할 수 없었다.

• 한국미생물학회:학술대회논문집
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• 한국미생물학회 2002년도 추계학술대회
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• pp.59-62
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• 2002

The role of a TolC homologue in the virulence of Vibrio vulnificus, a marine bacterium causing serious wound infection and fulminant septicemia in persons with underlying conditions, has been studied. TolC, an outer membrane protein, has been implicated in a variety of bacterial functions including export of diverse molecules ranging from large proteins to antibiotics. A homologue of the tolC gene of V. cholerae, which has been shown to be required for bile resistance, cytotoxicity and colonization of this organism, was identified in the partially determined genome sequence of V. vulnificus. To determine the role of TolC in the virulence of V. vulnificus, a TolC-deficient (TD) mutant was isolated by in vivo allelic exchange. Compared with the parent strain, the TD mutant was more sensitive to bile, and much less virulent in mice challenged subcutaneously. This mutant was noncytotoxic to the HEp-2 cells, but its metalloprotease and cytolysin activities in the culture supernatant were comparable to the parent strain. In addition, the resistance of the TD mutant to human serum bactericidal activity as well as its growth in either human or murine blood was not affected. Collectively, our data suggest that TolC may be involved in colonization and/or spread of V. vulnificus to the blood stream, probably by secreting a cytotoxin other than the cytolysin.

• 한국산학기술학회논문지
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• 제8권3호
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• pp.660-672
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• 2007

오늘날 벤처기업이 우수한 기술력과 첨단제품을 보유하고 있다 하더라도 시장에서 지속적인 경쟁우위를 위해서는 여러 제반 여건이 필요하겠지만 그 중에서도 효과적인 글로벌 마케팅 전략은 매우 중요한 부분이다. 따라서 본 연구는 벤처기업의 특징과 현황 그리고 마케팅전략에 관한 연구를 고찰하고 2006년 12월말까지 등록된 벤처기업 중 총 200개 업체를 대상으로 직접 방문하여 설문지를 작성하였으며 그 중 154개 업체의 자료를 통해 가설을 설정하고 연관분석을 실시하였다. 실증분석결과 성장단계에 따라 제품, 가격, 유통, 촉진정책에 차이가 있을 것이다. 라는 가설과 매출액에 따라서는 유통, 촉진정책에 차이가 있을 것이다. 라는 가설들이 채택되었다. 벤처기업은 기술개발을 통한 차별화된 제품개발과 마케팅 활동에 가장 큰 비중을 두고 있으며 매출에 미미한 창업초기일수록 인적, 물적, 기술적 자원과 정보수집의 한계로 적극적인 시장개척과 판촉활동에 소극적인 것으로 조사되었다.

• 정보처리학회논문지D
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• 제10D권1호
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• pp.101-108
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• 2003

동북아 중심 항만의 기반을 다지기 위해 자동화항만의 건설이 시급히 요청되고 있다. 따라서 우리나라에 적합한 자동화항만의 운영시스템 레이아웃 설계방안을 제시하고자 한다. 본 논문에서는 자동화항만의 운영시스템이 추구해야말 목표를 충족시키며, 각 자동화 장비를 통한 화물의 수출입 이동경포에 따라 운영시스템의 모델을 4가지로 구분하고 여러 입력 요소들을 변경시켜 가며 시행착오를 거쳐 동적으로 분석해 나감으로서 최적의 운영시스템 모델을 선정하고, 그에 대한 수출입화물별 야드 운영시스템 레이아웃을 설계하였다. 특히 미래의 자동화항만에서는 어떠한 자동화 장비를 사용하느냐에 따라 그 생산성이 달라진다. 그러나 현실적으로 비용측면과 현재의 작업 흐름을 도외시 할 수 없기 때문에 현재의 작업을 최적화하고 현재의 사용 장비와 자동화 장비의 대체로 작업의 혼선이 발생하지 않은 방법을 선택하여 레이아웃을 설계하였다. 본 논문의 야드 운영시스템에서 기술한 장비들은 Q/C(Quay Crane)을 제외한 모든 야드 장비가 완전자동화를 전제로 한 것이다.

• Journal of Information Processing Systems
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• 제16권2호
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• pp.246-260
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• 2020

IT Service Management (ITSM) achieves consolidated management for the IT services supporting the acquisition system, and no outside connections can be established with such ITSM. Issues pertaining to the D2B can be addressed to System Q&A or a Call Center for problem-solving. In other words, internal staff can take the necessary measures for problems by directly connecting with ITSM. Currently, diverse innovative technologies are being used in electronics and ubiquitous computing environments. This allows us to create a better world by providing the backbone for remarkable development in our human society in the fields of electronics, devices, computer science, and engineering. Following the expansion of IT services in the military acquisition sector such as Defense Electronic Procurement, military export/import support system, etc., customers' dependence on IT for conducting business with the military or related companies is increasing, including the military's dependence on the same technology for services to the public. Nonetheless, issues pertaining to the simplified/integrated management of complex IT service management systems, including slow system recovery, lack of integrated customer service window, and insufficient information sharing, have become the priority problems that IT managers are required to solve. Therefore, this study conducted research on the integrated management of IT services provided by Korea's national defense acquisition system, which was developed based on the existing system IT Infrastructure Library (ITIL) v2, and investigated the level of satisfaction with services with focus on ensuring that it can be used for understanding the necessity of the system and its advancement in the future.

• Journal of Microbiology and Biotechnology
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• 제9권3호
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• pp.235-242
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• 1999

We investigated the growth-inhibitory mechanism of Helicobacter pylori by omeprazole (OMP) and its activated sulfenamide (OAS). Using dithiothreitol (DTT) and 5,5'-dithio-bis[2-nitrobenzoic acid] (DTNB; Ellman's reagent), we first determined the relationship between the binding capacity of these compounds to H. pylori membrane and its significance to membrane P-type ATPase activity. After incubation of the intact H. pylori cells with either OMP or OAS, the residual quantity of free SH-groups on the cell membrane was measured, and, the resulting values were plotted as a function of time. From this experiment, we found that there was a considerable difference in the membrane-binding rates between OMP and OAS. At neutral pH, the disulfide bond formation on H. pylori membrane was completed within 2 min of incubation of the intact cells with OAS. By OMP, however, it was gradually formed, exceeding 10 min of incubation for completion, whereby, the extent of P-type ATPase inhibition appeared to be proportional to the disulfide forming rate. From this data, it was suggested that the disulfide formation might directly affect enzyme activity. Since OMP per se cannot yield a disulfide bond with cysteine, it is predicted that the enzyme inactivation must be caused by the OAS form. Accordingly, we postulated that, under the neutral pH, OMP could be converted to OAS in the course of transport. By extrapolating the inhibitory slopes, we could evaluate K₁ values, relating to their minimal inhibitory concentrations (MICs) for H. pylori growth. In these MIC ranges, H. pylori uptake or vesicular export of nutrients such as peptides were totally prohibited, but their effect in Escherichia coli were negligible. From these observations, we strongly suggest that the P-type ATPase activity is essential for the survival of H. pylori cells in particular.

• 패션비즈니스
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• 제5권1호
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• pp.145-156
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• 2001

The purpose of this study was to improve the fitness of Korean manufactured apparel products being exported to China and to provide for the basic data useful to the development of a torso prototypes for the Chinese women. For this purpose, Chinese college women aged between 18 and 24 were sampled to test the fitness of the Korean manufactured apparels for the Chinese women sample and address the problems of unfitness and thereupon. The results of this study can be summarized as follows; As a result of testing the fitness of the Korean manufactured apparels for the Chinese women, it was found that Chinese women felt more or less comfortable for the front of the jackets, but felt less comfortable with their side and back. Such a finding suggests that the Chinese women's postures are more turned back than the Korean women's. And also for the slacks, lack of a crotch length causes unnecessary pulls and creases from the back part to the crotch of a pair of slacks and the side line was not suitably placed. For this reason, the differences between the body shapes of Chinese and Korean women should be thoroughly considered when drawing the patterns to export to China.

• 기술혁신연구
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• 제18권1호
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• pp.99-121
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• 2010

이 논문에서는 2008년 한국제조업혁신조사를 이용하여 다양한 기업특성이 연구개발 정부지원의 수혜에 어떠한 영향을 끼치는가를 분석한다. 분석에는 정부지원 수혜 여부를 다양한 기업특성에 대해 회귀분석한 프로빗 모형이 이용되었다. 이 논문은 연구개발 정부지원의 수혜대상 선정 문제를 프로그램 단위가 아닌 국가 전체의 차원에서 본격적으로 다루었다는 점에서 의의를 지니며, 특히 지역 및 산업 변수의 영향을 분석한 것은 최초의 시도로 평가될 수 있다. 또한, 정부지원의 사전적 정책목표의 달성 여부를 실증분석 결과에 비추어 평가한다. 분석 결과, 기업규모와 수출이 정부지원 수혜에 긍정적인 영향을 끼치는 것으로 나타났으며, 혁신기업 지정, 연구소 보유, 연구인력 등 기업이 보유한 혁신 역량 또한 수혜확률을 높이는 것으로 나타났다. 또한, 산업별로는 화학산업과 자동차 산업이, 지역별로는 대경권 및 부경권이 특히 유리한 것으로 나타났다.

• Animal cells and systems
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• 제16권2호
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• pp.145-153
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• 2012

The pear psylla, $Cacopsylla$ $pyricola$ (Hemiptera: Psyllidae), is a serious insect pest of commercial pear crops. The species, which resides on pear trees throughout its life cycle, is rapidly spreading in some regions of the world. The population genetic structure of the species collected from several pear orchards in Korea was studied to understand the nature of dispersal and field ecology of the species. The 658-bp region of mitochondrial COI gene and the 716-bp long complete internal transcribed spacer 2 (ITS2) of the nuclear ribosomal DNA were sequenced. Unlike other previously studied insect pests, the COI-based genetic diversity of the pear psylla was extremely low (maximum sequence divergence of 0.15%). This finding allowed us to conclude that the species may have been introduced in Korea relatively recently. ITS2 sequence-based analyses of phylogeny, population differentiation, gene flow, and hierarchical population structure all concordantly suggested that the pear psylla populations in Korea are neither genetically isolated nor hampered for gene flow. These genetic data are concordant with the dispersal of an overwintering winterform morph outside the non-pear habitat in the fall.