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Significant Reperfusion on $^{99m}Tc-HMPAO$ SPECT in a Case of Subacute MCA Infarction (한의학적 치료로 $^{99m}Tc-HMPAO$ SPECT상 현저한 재관류를 보인 아급성기 중대뇌동맥경색 환자 1례)

  • Park, Jung-Mi;Jung, Woo-Sang;Seo, Al-An
    • The Journal of Internal Korean Medicine
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    • v.22 no.3
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    • pp.437-442
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    • 2001
  • For ischemic cerebrovascular disease, it is well known that early luxury perfusion is related to a good clinical outcome and single photon emission computed tomography(SPECT) has the potential for providing useful information about regional cerebral blood flow. We report one case of Rt. MCA infarction mainly treated by oriental medicine and revealed luxury perfusion without thrombolysis. In acute stage, neurological deficits of the patient were very severe. 99mTc-HMPAO SPECT images obtained 10days after the attack showed large perfusion defect in the Rt. MCA territory. We followed up 99mTc-HMPAO SPECT 40days after the ictus. Despite of the poor early perfusion, we found considerably improved perfusion and neurological improvement.

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Hematological Effects of Water Extracts of Cham-Dang-Gui on Dietary Induced Iron Deficient Anemia Rat (식이로 유도된 철 결핍성 빈혈 흰쥐에서 참 당귀 열수추출물이 혈액학적 빈혈지표에 미치는 영향)

  • Woo, Jeong-Hwa;Choi, In-Young;Choue, Ryo-Won
    • Journal of Nutrition and Health
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    • v.40 no.5
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    • pp.428-434
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    • 2007
  • Cham-dang-gui (Angelica gigas nakai) has been used in traditional Korean medicine to treat hemotological disorders. The purpose of this study is to investigate the hematological effects of water extracts of Cham-dang-gui in rats with anemia induced by iron-free diets. Rats were divided into two groups, a regular diet group (RD) and an iron-free diet group (FeD). The iron-free diet group was then subdivided into the following three treatment groups: saline (1.0 ml/kgBW/day, FeDS), Cham-dang-gui (1.0 g/kgBW/day, FeDA), and iron (iron succinylate 14 mg/kgBW/day, FeDFe) groups. Rats were fed an iron-free diet for 6 weeks to induce iron-deficient anemia, and subsequently underwent the treatments, during which they were fed an iron-free diet for 3 weeks followed by a regular diet for 3 weeks. Body weights of the iron-diet groups (FeDS, FeDA, FeDFe) were lower than that of RD group. The blood levels of Hgb, Hct, MCV, MCH and TIBC were significantly higher in RD and FeDFe groups than those of other groups. The water extract of Cham-dang-gui with iron-free diet has no hematological effects. A regular diet followed by iron-free diets significantly increased blood levels of Hgb, Hct, and MCH.

Operational Efficiency Analysis of ODCYs as Logistic Facilities in the Hinterland of Busan North Port : Based on DEA Modeling (DEA모형을 이용한 부산항 배후물류시설 ODCY의 운영효율성 분석)

  • Seo, Dong-Gyun
    • Journal of Korea Port Economic Association
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    • v.27 no.4
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    • pp.51-71
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    • 2011
  • The purpose of this study is to use DEA modeling to make an analysis on 12 ODCYs in the hinterland of Busan North Port, so that it may propose possible ways to efficiently operate them. For analysis, this study adopted 3 input factors such as CY area, number of employees and number of cargo work equipments and also adopted 1 output factor, i.e. container throughput. According to the analysis DEA-CCR model, it was found that Chunil(YongDang CY) was the most efficient one among companies engaged in the operation of ODCY. And it was found that KCTC(YongDang CY), Kukbo(U-Am CY), KORAIL(BusanJin CY) and Hanjin (JaeSong CY) would need to boost the container throughput 5 or more times higher than current throughput with a view to improving cargo handling efficiency, while Sebang(U-Am CY), KCTC(U-Am CY), KCTC(YongDang CY), Hyopsung(YongDang CY) and Kukbo(U-Am CY) need to work on personnel restructuring targeted to current employees. Based on the analysis DEA-BCC model, it was found that Chunil(YongDang CY), Dongbu(ShinYoung GamMan CY), Intergis(GamMan CY) and Sebang(U-Am CY) were efficient companies, but KCTC(YongDang CY), Kukbo(U-Am CY), KORAIL(BusanJin CY) and Hanjin(JaeSong CY) were inefficient companies. Particularly, it was found that both KCTC(U-Am CY) and Kukbo(U-Am CY) would need to try harder to carry out personnel reshuffle than other comparable companies.

Evaluation of Variation Method to Improve the Sensitivity of Immunoradiometric Assay (면역방사계수측정법의 민감도 향상을 위한 변법의 평가)

  • Won-Hyun Kwon;Mi-Ji Kang;;Ji-Sol Park;Jung-In Kim;Kyung-Jae Lee
    • The Korean Journal of Nuclear Medicine Technology
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    • v.27 no.1
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    • pp.29-35
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    • 2023
  • Purpose The concentration of PSA (Prostate Specific Antigen) after radical prostatectomy in prostate cancer patients is a predictor of biochemical recurrence, and the AUA (American Urological Association) is defined as biochemical recurrence when the concentration of PSA is measured at 0.2 ng/mL or more, and when the concentration is measured at 0.2 ng/mL or more at the retest. This standard is also applied our hospital. In this laboratory, the PSA reagent using IRMA (Immunoradiometric Assay) is used, and the sensitivity at a very low value was not as good as the reagent used in the department of laboratory medicine. This study aims to increase the reliability of the results by improving the precision and sensitivity of very low values. Materials and Methods As a reagent for the study, PSA reagent using IRMA was used. As a method to improve the precision and sensitivity of very low values, a variation method on the serum volume(25 uL, 50 uL, 100 uL, 200 uL) was studied, and variation usefulness evaluation was conducted. The evaluation items were compared the results of precision, analytical sensitivity, recovery rate, dilution test, high-dose hook effect test, parallel test and very low concentration values(n = 20). Results The validation results were displayed in the order of 25 uL, 50 uL, 100 uL, 200 uL. As the serum volume increased, it was confirmed that CV (Coefficient of Variation)(%) improved. Analytical sensitivity(ng/mL) was 0.038, 0.041, 0.017, 0.015 and recovery rate(%) was 101±3, 101±3, 99±2, 97±4. very low concentration values(ng/mL) between each volume(n=20) were 0.135±0.068, 0.076±0.050, 0.048±0.034, 0.046±0.034. and high dose hook effect appeared as the serum volume increased. Conclusion Through the variation usefulness evaluation, it was confirmed that as the serum volume increased, the precision and sensitivity improved at very low concentration values. However, it is necessary to pay special attention to the occurrence of high-dose hook effect as the serum volume increases. In the case of tests that requires very low concentration values, it is thought that the reliability of the result will be increased if the variation method is properly used after the variation usefulness evaluation.

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The instruction of comparative study on Lao Zi Note of Park Sae Dang and Hayashi La Zan (박세당(朴世堂)의 『신주도덕경(新註道德經)』과 임라산(林羅山)의 『노자초해(老子抄解)』 비교 연구 서설)

  • Cho, Hansuk
    • The Journal of Korean Philosophical History
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    • no.28
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    • pp.297-329
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    • 2010
  • This article is a preliminary essay for comparative study on Lao Zi Note of Park Sae Dang who lived Lee Dynasty in 17C and Hayashi La Zan who lived Doku Kawa Bakuhu in 17C. This article have two points at issue. First one is the their challenge that resisted the dogma of their own age. And the other one is their challenge of thaught had the academic background of the Lao Zi Note. They had a their own Lao Zi Note, Park Sae Dang朴世堂 had a New Note of Lao Zi 新註道德經 and Hayashi La Zan 林羅山 had a Selection Note of Lao Zi 老子抄解. However there are some different points between Park Sae Dang and Hayashi La Zan. The Hayashi La Zan's comprehension of Lao Zi followed in Lao Zi Note of Lin Xi Yi 林希逸 who had a point of Confucian comprehension of Lao Zi, so the study of Taoism of Hayashi La Zan excepted Zhuang zi. Hayashi La Zan concentrated on only Confucian comprehension of Lao Zi because Lin Xi Yi's Note of Zhuang Zi had a point of Zen Buddhism. However Park Sae Dang's the study of Taoism has Lao Zi and Zhuang Zi. He understood Lao Zi and Zhuang Zi in a base on Confucian comprehension. He indicated Confucian moral principle 修身治人 for a equal point of between Confucianism and Taoism. And he understood Cheng Xin成心 in Qiwulun in Zhuang Zi is similar to Xing性 of Xing Shan性善 in Meng Zi. Park Sae Dang analyzed not simply Lao Zi but also Zhuang Zi in a base on Confucian comprehension.

A study on the Character of Water Quality according to the Flux in Pal-Dang Reservoir (팔당호 유량변동에 따른 수질특성에 관한 연구)

  • 김종민
    • Journal of environmental and Sanitary engineering
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    • v.10 no.1
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    • pp.12-24
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    • 1995
  • I tried to evaluate the reason of the monthly variation of water quality according to the hydrologic character of Pal- dang reservoir inflow variation. The result of this study is as below; 1 ) COD, BOD, Total- nitrogen and Total- phosphate concentration increase generally according to the flux and Total- phosphate concentration is the most affected item by flux. 2) COD, BOD, Total- nitrogen and Total- phosphate concentration increase according the flux, but they begin to decrease at the below point ; COD · 1,154 CMS, BOD : 1,007 (CMS cubicmeter per second ) and Inflow- Concentration interrelation formula is as below; table omitted.

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Practical Guide to NMR-based Metabolomics - II : Metabolite Identification & Quantification

  • Jung, Young-Sang
    • Journal of the Korean Magnetic Resonance Society
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    • v.22 no.1
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    • pp.10-17
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    • 2018
  • Metabolite identification and quantification are one of the foremost important issues in metabolomics. In NMR based metabolomics, mainly one-dimensional proton NMR spectra of biofluids, such as urine and serum are measured. However, it is not always easy to identify and quantify metabolites in one-dimensional proton NMR spectra. This article introduces useful public metabolite databases, metabolic profiling software, and articles.

Practical Guide to NMR-based Metabolomics - III : NMR Spectrum Processing and Multivariate Analysis

  • Jung, Young-Sang
    • Journal of the Korean Magnetic Resonance Society
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    • v.22 no.3
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    • pp.46-53
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    • 2018
  • NMR-based metabolomics needs various knowledge to elucidate metabolic perturbation such as NMR experiments, NMR spectrum processing, raw data processing, metabolite identification, statistical analysis, and metabolic pathway analysis regarding technical aspects. Among them, some concepts of raw data processing and multivariate analysis are not easy to understand but are important to correctly interpret metabolic profile. This article introduces NMR spectrum processing, raw data processing, and multivariate analysis.

A Study on the Utilization of Resident Living Space in Upper Class Residence of CHO-SUN Dynasity - Through the Rites of Passage in the MAN-CHUI-DANG - (조선시대 상류주택의 주생활공간 이용에 대한 연구 - 만취당에서의 통과의례를 중심으로 -)

  • 백영흠
    • Journal of the Korean housing association
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    • v.1 no.1
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    • pp.103-111
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    • 1990
  • This study has researched on the utilization of living space through interview with a owner of the MAN-CHUI-DANC. The aim of the study is to grasp-the resident living and dwelling ceremony through rites of passase of the MAN-CHUI-DANG among the upper class residence of Korean traditional house A result of this study , Korean traditional house have been so inhered multipurpositive and adaptability that dwelling living space for the rites of passage is always separation, transition, coordination as living aspect.

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