Significant Reperfusion on $^{99m}Tc-HMPAO$ SPECT in a Case of Subacute MCA Infarction

한의학적 치료로 $^{99m}Tc-HMPAO$ SPECT상 현저한 재관류를 보인 아급성기 중대뇌동맥경색 환자 1례

  • Park, Jung-Mi (Dept. of Internal medicine, Pun-dang Cha Oriental Hospital) ;
  • Jung, Woo-Sang (Dept. of Internal medicine, Pun-dang Cha Oriental Hospital) ;
  • Seo, Al-An (Dept. of Internal medicine, Pun-dang Cha Oriental Hospital)
  • Published : 2001.09.30

Abstract

For ischemic cerebrovascular disease, it is well known that early luxury perfusion is related to a good clinical outcome and single photon emission computed tomography(SPECT) has the potential for providing useful information about regional cerebral blood flow. We report one case of Rt. MCA infarction mainly treated by oriental medicine and revealed luxury perfusion without thrombolysis. In acute stage, neurological deficits of the patient were very severe. 99mTc-HMPAO SPECT images obtained 10days after the attack showed large perfusion defect in the Rt. MCA territory. We followed up 99mTc-HMPAO SPECT 40days after the ictus. Despite of the poor early perfusion, we found considerably improved perfusion and neurological improvement.

Keywords

References

  1. Stroke v.29 Spontaneous reperfusion after ischemic stroke is associated with improved outcome Barber, P.A.;Davis, S.M.;Infeld, B.;Baird, A.E.;Donnan, G.A.;Jolley, D.(et al.)
  2. J Comput Assit Tomogr v.23 no.SUP.1 Current and future imaging of acute cerebral ischemia : assessment of tissue viability by perfusion imaging Ueda, T.;Yuh, W.T.C.;Maley, J.E.;Otake, S.;Quets, J.P.;Taoka, T(et al.)
  3. Stroke v.28 Sensitivity and Sepcificity of 99mTc-HMPAO SPECT cerebral perfusion measurements during the first 48 hours for the localization of cerebral infarction Baird, A.E.;Austin, M.C.;McKay, W.J.;Donnan, G.A.
  4. Arch Neurol v.51 Spontaneous reperfusion of cerebral infarcts in patients with acute stroke incidence, time course, and clinical outcome in the Copenhagen Stroke Study Jorgensen, H.S.;Sperling, B.;Nakayama, H.;Raaschou, H.O.;Olsen, T.S.
  5. 대한신경과학회지 v.19 no.2 급성 중뇌동맥영역 뇌경색에서 확산강조 MRI와 Tc^{99m}$-ECD SPECT 소견 : 부피 측정 분석을 이용한 임상 상태 및 예후와의 비교 황인용;이성민;최성민;조연희;김병채;김명규(외)
  6. Stroke v.27 Simple visual analysis of brain perfusion on HMPAO SPECT predicts early outcome in acute stroke Alexandrov, A.V.;Black, S.E.;Ehrlich, L.E.;Bladin, C.F.;Smurawska, L.T.;Pirisi, A.(et al.)
  7. A Neural Associ v.40 no.2 Spontaneous neurological recovery after stroke and the fate of the ischemic penumbra Furlan, M.;Marchal, G.;Viader, F.;Derlon, J.M.;Baron, J.C.
  8. Stroke v.25 Reperfusion after thrombolytic therapy in ischemic stroke measured by single-photon emission computed tomography Baird, A.E.;Donnan, G.A.;Austin, M.C.;Fitt, G.J.;Davis, S.M.;McKay, W.J.
  9. Clin Nucl Med v.24 no.8 Evaluation of reperfusion and recovery of brain fuction before and after intracarotid arterial urokinase therapy in acute cerebral infarction with brain SPECT Ryu, Y.H.;Chung, T.S.;Yoon, P.H.;Kim, D.I.;Lee, J.D.;Lee, B.I.(et al.)
  10. Stroke v.28 Predictors of hemorrhagic transformation occurring spontaneously and on anditicoagulants in patients with acute ischemic stroke Alexandrov, A.V.;Black, S.E.;Ehrlich, L.E.;Caldwell, C.B.;Norris, J.W.
  11. JAMA v.276 Streptokinase for acute ischemic stroke with relationship to time of adminstration Donnan, G.A.;Davis, S.M.;Chambers, B.;Gates, P.C.;Hankey, G.J.;McNeil, J.J.(et al.)
  12. 대한한방내과학회지 v.21 no.1 腦卒中患者에 있어서 治療經過에 따른 腦血流 變化-Brain SPECT 結果를 중심으로- 전상윤;강화정;흥석;김종석;송호천;범희승
  13. Proc Natl Acad Sci USA v.95 New findings of the correlation between acupoints and corresponding brain cortices using functional MRI Cho, Z.H.;Chung, S.C.;Jones, J.P.;Park, J.B.;Park, H.J.;Lee, H.J.(et al.)
  14. 대한핵의학회지 v.34 no.6 $Tc-^{99m}ECD$뇌혈류 SPECT를 이용한 백회, 인중, 합곡, 족삼리, 삼음교에서 체침의 뇌혈류에 대한 효과 송호천;범희승;강화정;안수기;김성민;정환정(외)
  15. 한의학회지 v.12 no.1 방풍통성산(防風通聖散)이 고혈압 고지혈에 미치는 영향 이남훈;이경섭
  16. 대한동의병리학회 v.6 no.1 청심연자음이 Sreptozotocin으로 유발한 백서의 고혈당에 미치는 영향 김수웅;엄현섭;김완희
  17. Clinical Nuclear Medicine v.25 no.4 A qualitative analysis of brain SPECT for prognostication of gross motor development in children with cerebral palsy Yim, S.Y.;Lee, I.Y.;Park, C.H.;Kim, O.H.
  18. J Nucl Med v.38 Volumetric analysis of cerebral hypoperfusion on SPECT : Validation and reliability Infeld, B.;Binns, D.;Lichtenstein, M.;Hopper, J.L.;Davis, S.M.