• 한방비만학회지
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• 제22권1호
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• pp.1-10
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• 2022

Objectives: To investigate the protective effect of hesperidin and hesperetin against oxidative stress in 2,2'-azobis (2-aminopropane) dihydrochloride (AAPH)-induced liver toxicity in rats. Methods: Hesperidin or hesperetin (200 mg/kg/day, respectively) was orally administered for 7 days once daily in rats. Subsequently, AAPH (50 mg/kg/day) was administered intraperitoneally. Lipid peroxidation, nitric oxide production, catalase activity, and protein expressions of nuclear factor-kappa B (NF-κB) and inducible nitric oxide synthase (iNOS) in the liver tissues were measured. Results: Administration of hesperidin and hesperetin significantly decreased serum aspartate transaminase and alanine transaminase levels in AAPH-induced oxidative stress liver tissues compared with control group. Lipid peroxidation and nitric oxide (NO) production were also significantly reduced by hesperidin and hesperetin in AAPH-induced oxidative stress liver tissues. In particular, lipid peroxidation levels of hesperetin-administered group significantly decreased to 5.02 nmole/mg protein in oxidative stress rats. Hesperidin and hesperetin significantly increased antioxidant activity, such as that of catalase. Furthermore, administration of hesperidin and hesperetin substantially down-regulated the expression of NF-κB and iNOS in liver tissues. Administration of hesperidin reduced NO levels and iNOS expression more than in the hesperetin-administered group. Conclusions: Administration of hesperidin and hesperetin led to a reduction in AAPH-induced liver toxicity by regulating oxidative stress.

• 한국응용과학기술학회지
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• 제41권2호
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• pp.498-507
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• 2024

In the field of mental health care, long-term healing programs have gained widespread recognition for their effectiveness in promoting well-being. However, the efficacy of shorter-term interventions, such as 1-night 2-day programs, remains relatively understudied. The primary objective of this initiative is twofold: firstly, to enhance the overall well-being and resilience of participants, and secondly, to investigate the program's potential to ameliorate specific mental health indicators. These indicators include physical stress levels, autonomic nervous system health, brain activity, brain stress, and concentration. A 1-night 2-day mental health healing program was implemented for 560 civil servants from Jeollanam-do (mean age 47.87 yrs). The focus was on measuring changes through baseline assessments before participation and post-program assessments upon completion. Measurements included physical stress index, autonomic nervous system health, brain activity level, brain stress, and brain concentration. There was a significant decrease in physical stress, as well as a significant decrease in autonomic nervous system health (p<0.05). Although there was no significant difference in brain activity level, there was a tendency for brain activity level to stabilize in the high-frequency range. Additionally, a significant decrease in stress levels and an improvement in concentration were observed. Incorporating 1-night 2-day relaxation programs into our daily lives offers a holistic approach to caring for both our physical and mental health, providing essential moments of rejuvenation and self-care that contribute to overall well-being and fulfillment.

• 한국환경농학회지
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• 제27권4호
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• pp.441-446
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• 2008

여름철에 고온 스트레스로 인하여 산란계의 산란율이 다른 계절에 비하여 현저히 낮다. 따라서 본 연구는 여름철 기후조건에서 산란율과 계사 내 1일 최고온도 사이의 관계, 산란율과 음수량 사이의 관계, 산란율과 사료섭취량 사이의 관계 등을 구명하기 위하여 수행되었으며, 연구결과는 다음과 같다. 산란계사 내의1일 최고온도가 $33^{\circ}C$ 이상이 되었을 때 산란율이 현저히 저하되었고, 음수량과 사료섭취량이 각각 $490\;mL\;bird^{-1}\;day^{-1}$, $240\;g\;bird^{-1}\;day^{-1}$까지 증가함에 따라 산란율이 급격히 증가하였으나 그 이상에서는 거의 증가하지 않았다. 이상의 연구결과를 고려해 볼 때, 여름철에 산란계의 산란율을 향상시키기 위해서는 지붕을 충분히 단열처리하고, 만약 지붕이 단열처리 되지 않았다면 차광막을 설치하며, 하루중에 최고 온도가 되는 오후 2시경을 전.후로 지붕에 시원한 물을 살수하며, $15^{\circ}C$ 정도의 시원한 물을 제공하는 것이 바람직할 것으로 판단된다.

• 보건교육건강증진학회지
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• 제22권2호
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• pp.195-213
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• 2005

Objectives: This study aims to determine fostering stress and mental health state that mothers of handicapped children perceive as primary care givers and to analyze their demand for information assistance in order to release their stress so that it can provide materials that contribute to establishment of assistance system for families with handicapped children. Methods: The research subjects were 340 mothers whose children went to a nursery for special children, 3 general nurseries and 6 special schools in Daegu, and the data were collected using structures questionnaires. The survey analyzed mothers' fostering stress, their demand for fostering information assistance, children's daily activity abilities. Component concepts of each scale was validated by adopting confirmatory factor analysis, and factors affecting demand for fostering information assistance were analyzed by adopting covariance structural analysis. Results: Younger mothers tend to have higher demand for information, and mothers with younger children or children with double handicaps also have higher demand. Mothers under 30 have the lowest demand for public health and medical care assistance and for home and community life assistance, while mothers with children with physical handicaps have the highest. The validity of component concepts was verified by categorizing as cognitive structure models fostering stress, information demand, children's daily activity abilities, and their appropriateness was evaluated through confirmatory factor analysis using structural equation modelling. And then, GFI (more than 0.9), CFI (more than 0.9), TLI (more than 0.9) and RMSAE (less than 0.08) were used to evaluate the appropriateness. It was found that all the component concepts are valid, as every item is within appropriate range. The result of analyzing information demand demonstrated that children's handicap levels significantly affect their mothers' mental health, while fostering stress significantly affect mothers' metal health, information demand. As well, it was confirmed that mothers' mental health has a significant effect on information demand. Conclusions: Therefore, to reduce special children's mothers' uncertainty, helplessness and fostering burden, it is necessary to provide them with information on children's challenges, development and fostering and to offer them quality public health, medical care and welfare assistance along with family and local community life assistance.

• Journal of Nutrition and Health
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• 제32권6호
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• pp.644-653
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• 1999

Background : Excessive intakes of $\omega$6 polyunsaturated fatty acid (PUFA) can increase oxidative stress, which may increase insulin resistance and could be the cause of metabolic syndrome X such as diabetes mellitus. One of the ways to reduce oxidative stress is the consumption of antioxidants such as vitamin E. It is controversial that vitamin E intakes may alleviate insulin resistance. The purpose of the study was whether high vitamin E intake may influence whole body glucose disposal rate(GDR), glycogen deposites, triglyceride content, lipid peroxide levels and antioxidant enzyme activities in Sprague Dawley rats fed high $\omega$6 PUFA diest. Methods : Sprague Dawley rats were divided into three groups. The control group consumed chow diet. High and low vitamin E groups consumed 40% PUFA of total energy intakes. One kilogram of diet mixture contained 300IU of $\alpha$-tocopherol in high vitamin E group, while it had 30 IU in low vitamin E group. Diets were given for 8 weeks. After 7 were of diet consumption, indwelling catheters were inserted in carotid artery and jugular vein of all rats so that GDR could be measured in awake and unstressed state. Results : Daily PUFA intakes were lower in the control group than others. Daily vitamin E intake of high vitamin E group was about ten times higher than those of low vitamin E group and the control group(p<0.0001). $\alpha$-tocopherol content in lier was highest in the high vitamin E group. GDR of the control group was 24% higher than others, and vitamin E intakes did not affect GDR. Glycogen deposit of liver in the control group was significantly higher than others, and it was not altered by vitamin E supplementation. Muscle glycogne content showed a similar tendency as liver glycogen in different diet groups. Triglyceride deposit in muscle was not different among groups. Lipid peroxide content of liver in the high vitamin E group was lower than the low of glutathione peroxidase were lowered in low vitamin E group than others, however, those of superoxide dismutase and catalase were not different. Conclusions : High vitamin E intakes can decrease oxidative stress in rats fed high (())-6 PUFA diet, but they cannot alleviate insulin resistance. Thus, increased oxidative stress through high (())-6 PUFA diet may be minimal for influencing insulin resistance.

• Journal of Animal Science and Technology
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• 제64권1호
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• pp.84-96
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• 2022

The current study was conducted to evaluate the effect of calcium-enriched fatty acid supplementation on the growth performance, blood metabolites, intestinal morphology, carcass traits, and nutrient digestibility of broilers subjected to chronic heat stress. A total of 210 one-day-old broiler chicks (40.12 ± 0.25 g) were randomly allocated to one of five dietary treatments, to obtain six replicates per treatment. Broilers were subjected to chronic heat stress from day 21 to day 35, post-hatching, at 34℃ for 9 h per day. The body weight (BW) and feed intake of the experimental broilers were recorded weekly, and the average daily gain (ADG) and feed conversion ratio (FCR) were calculated accordingly. Rectal temperature was measured to compare the basal body temperatures between individuals, and blood samples were collected on days 21 and 35 to evaluate basal body temperature, serum total cholesterol, and the triglyceride content of the broilers. On days 21 and 35, one broiler from each cage (n=6) was euthanized to measure carcass trait parameters, nutrient digestibility in digesta, and intestinal morphology. On days 14, 28, and 35, the broilers fed 2.0% calcium-enriched fatty acids had higher BW (p < 0.05) than those fed the other diets. However, no differences (p > 0.05) were found in the average daily feed intake (ADFI) between dietary treatments over the 35 experimental days. On the other hand, on day 21, post-hatching, the broilers fed the 2.0% calcium-enriched fatty acid diet had improved (p < 0.05) dietary feed efficiencies compared to the other treatments. On day 28, the broilers fed the 5.0% of calcium-enriched fatty acid diet also had higher (p < 0.05) dietary feed efficiencies than those fed with the other dietary treatments. No effects (p > 0.05) on carcass weight, nutrient digestibility, intestinal morphology, or blood parameters were found between broilers fed with dietary treatments. This study demonstrated that the inclusion of an additive, containing 2.0% calcium-enriched fatty acid, to broiler diet could ameliorate the negative growth performance of broilers; and no interaction (p > 0.05) was observed between the calcium-enriched fatty acid and nutrient digestibility, digestive anatomy, blood metabolism, and carcass traits of broilers subjected to chronic heat stress conditions for 35 days post-hatching.

• 문화기술의 융합
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• 제8권5호
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• pp.161-169
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• 2022

본 연구는 대학생의 카페인 섭취와 스트레스가 수면의 질에 미치는 영향을 확인하고자 시행하였다. 연구 대상 및 자료수집은 2022년 2월 14일부터 3월 13일까지 구글(Google) 설문지를 통해 대학생 269명을 대상으로 하였고, 연구설계는 서술적 조사연구이다. 통계분석은 SPSS 27.0 버전을 사용하여 t-test, one way ANOVA 및 Scheffe' test로 분석하였다. 연구 결과, 우리나라 성인의 1일 카페인 권장섭취량에는 크게 못 미치는 수준이나, 대부분의 대학생이 한국 성인 하루 평균 카페인 섭취량보다 많이 섭취하는 것으로 나타났다. 대학생의 수면의 질은 스트레스(r =.32, p=<.001)와 카페인 섭취(r =.24, p=.001)와 양의 상관관계가 있는 것으로 나타났다. 수면의 질에 영향을 미치는 요인은 체질량 지수와(β=.19, p<.001) 스트레스(β=.37 p<.001), 흡연(β=-.18, p=.001), 카페인 섭취(β=.15, p=.005) 순이었고 모형의 설명력은 24.8%이었다.

• 시큐리티연구
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• 제13호
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• pp.403-422
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• 2007

사람들은 스트레스라고 하면 보통 부정적인 측면만을 생각하곤 하는데 스트레스는 긍정적인 측면도 있고 부정적인 측면도 있다. 긍정적이든 부정적이든 스트레스는 변화로부터 기인한다. 변화는 삶에 있어서 필연적인 것이다. 결국 사람들은 어쩔 수 없이 스트레스를 경험할 수밖에 없다. 경찰이라는 직업은 업무 특성상 스트레스를 많이 받는 직업들 중의 하나이다. 경찰업무는 신체적${\cdot}$감정적인 긴장 상태에 이르게 함으로써 경찰공무원들의 스트레스를 유발시킨다. 위험, 좌절, 과도한 업무부담, 가족 및 동료 그리고 주민들의 이해 부족은 경찰공무원의 스트레스를 유발시키는 요인이 된다. 그렇기 때문에 뉴욕에 본부를 둔 미국 스트레스 연구소는 경찰을 스트레스가 가장 많은 10개 직업들 중 하나로 선정하기도 했다. 따라서 이 연구에서는 의료 모델과 조직보건 모델의 관점에서 경찰공무원의 스트레스 관리방안을 제시하였다. 의료 모델에서는 경찰공무원 개인적 차원에서 제거, 대처, 상담을 통한 스트레스 관리방안을 제시하였으며, 조직보건 모델에서는 경찰관리자의 차원에서 첫째, 인사제도의 합리화, 둘째, 복지 증진, 셋째, 경찰조직의 민주적 운영, 넷째, 원만한 대민관계 유지, 다섯째, 경찰공무원 가족을 위한 스트레스 관리 프로그램 개발 등을 제시하였다.

• 기본간호학회지
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• 제8권1호
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• pp.81-94
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• 2001

The purpose of this study was to identify levels of activity of daily living, self-efficacy. stroke specific quality of life and need for self-help management program for patients with hemiplegia in the home. Data were collected from June to November, 2000 and subjects were 88 poststroke patients who lived in Seoul and Kyunggi-do. The questionnaire consisted of 5 scales: activities of daily living, self-efficacy, stroke specific qulaity of life and need for a self-help management program. Data were analyzed using frequencies, percent, paired t-test, and Pearson's correlation coefficient with the SAS(version 6.12) program. The results are as follows ; 1) Most of subjects were Partially independent in ADL, but they needed assist once to do dressing, bathing meal preparation and house keeping work. 2) The mean self-efficacy score was 54.89(range : 1 to 80) and the individual differences were large. 3) Subjects responded that they were satisfied on the stroke specific quality of life scale totaled 65.8%. This value is comparatively low, especially for social role(51.4%), family functioning(58.3%) and mood (62.2%). 4) The highest needs for self-help management programs were for physical therapy, stress management, and range of motion exercise and the lowest needs were for elimination management and training, family counseling, and speech therapy. 5) On the demographic variables, sex showed significant differences for the dependent variables. Females had higher scores than males for IADL, self-efficacy, stroke-specific quality of life, and need for self-help management. 6) Age had high negative correlation with ADL, self-efficacy and stroke specific quality of life. Age was also correlated with need for self-help management. In conclusion, there was a high correlation for ADL, Self-efficacy and Quality of life in poststroke patients of home. The patient with a stroke also had a strong need for self-help management programs especially physical therapy and stress management. Therefore rehabilitation programs based on self-efficacy enhancement need to be developed in order to promote independent living for patients with hemiplegia.

• Animal Bioscience
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• 제34권11호
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• pp.1784-1793
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• 2021

Objective: An experiment was conducted to evaluate the effects of bamboo leaf extract (BLE) on the production performance, rumen fermentation parameters, and rumen bacterial communities of heat-stressed dairy cows. Methods: The experiment comprised a 14-day adaptation period and a 21-day experimental period and was conducted in a high-temperature and humidity environment (daily mean ambient temperature = 33.5℃±1.3℃; daily mean relative humidity = 64.9%±0.8%, daily mean temperature-humidity index = 86.2±0.4). Twelve Holstein dairy cows were randomly allocated into two groups. A total mixed ration supplemented with BLE at 0 (CON) and 1.3 g/kg dry matter (DM) were fed, respectively. Feed intake and milk yield were recorded daily. Milk samples were collected on 1, 11, and 21 d of the experimental period to analyze milk performance. Rumen fluid samples were collected on 21 d of the experimental period to analyze rumen fermentation parameters and rumen bacterial communities. Results: Compared with the control group, supplementation of BLE increased milk yield (p<0.01), milk fat yield (p = 0.04), 4% fat-corrected milk (p<0.01) and milk fat content (p<0.01); reduced somatic cell count (p<0.01). No differences in DM intake and milk protein or lactose content were observed between two groups. Supplementation of BLE also increased the rumen total volatile fatty acid (p<0.01), acetate (p<0.01), butyrate (p<0.01), and valerate (p = 0.05) concentrations. However, no significant effects were observed on rumen pH, ammonia nitrogen, propionate, acetate/propionate ratio, isobutyrate, or isovalerate. Furthermore, BLE increased the rumen bacterial abundance and the diversity of the rumen bacterial community. The BLE reduced the Firmicutes/Bacteroidetes abundance ratio and increased the abundances of Butyrivibrio_2 (p<0.01) and Ruminococcus_2 (p<0.01). Conclusion: The BLE supplementation at 1.3 g/kg DM could improve production performance and rumen fermentation in dairy cows during heat stress.