• Title/Summary/Keyword: DO$_3$ Structure

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Herbicidal Activity and Persistency in Aqueous Solution of Ortho Disubstituted Benzenesulfonyl Urea Derivatives (새로운 Ortho 이치환 Benzenesulfonyl Urea 유도체의 제초활성과 수용액중의 잔류성)

  • Kim, Yong-Jip;Chang, Hae-Sung;Kim, Dae-Whang;Sung, Nack-Do
    • Applied Biological Chemistry
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    • v.38 no.6
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    • pp.570-576
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    • 1995
  • The new sixteen herbicidal N-2-(1-hydroxy-2-fluoroethyl)-6-substituted(X)-benzenesulfonyl-N'-4,6-dimethoxypyrimidinyl-2-yl urea derivatives(S) were synthesized and thier herbicidal activities$(pI_{50})$ in vivo against rice(Orysa Sativa L.), Barnyard grass(Echninochloa orizicola) and Bulrush(Scirpus juncoides) were measured by the pot test under paddy conditions. The structure activity relationship(SAR) were studied using the physicochemical parameters of ortho-substituents(X) and hydrolysis rate constant(logk) and herbicidal activities by the multiple regression technique. The SAR suggested that the herbicidal activities were more dependant on the hydrolysis rate constant(logk>0) than the steric constants $(Es, small width($B_4$) and length($L_1$). Among them, halogens(2 & 5), methyl(15) and non(H) substituent(1) showed higher herbicidal activity for weeds which was not tolerent to rise and weeds. The herbicidal activity was increased and the persistency in aqueous solution was decreased by electron donating(${\sigma}0<0$) groups as ortho-substituent(X). From the relationship equation between herbicidal activity and hydrolysis rate constant, it was assumed that the both reactions would be proceeds with similar process. And the conditions on the ortho substituents to show higher herbicidal activity and the persistency in aqueous solution were also discussed.

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The Road Map of Animation Festival in Korea through the Comparative Analysis of 4 International Animation Festivals (4대 국제애니메이션영화제 비교분석을 통한 한국애니메이션영화제 발전방향)

  • Choi, Young-Chul;Choi, Seung-Rak
    • Cartoon and Animation Studies
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    • s.25
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    • pp.177-201
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    • 2011
  • This article intends to draw the Road map of Korean International Animation Festival through the research of background and its identity of 4 International Animation Film Festivals Such as Annecy, Zagreb, Ottawa and Hiroshima. I was given opportunity to visit Annecy since 2009, it brought me to the real attraction of animation for watching of pleasure and passion of the people those who love animations. For the combining more advanced system and structure for Animation Festival in Korea, I had to do research all the information from the documents from the Annecy Collections. though I have not get the chance to go others except Annecy, However, I could get their background and history whenever I met the other Festival Committee Members. These Festivals showed us successful Road Map for the Animation Festivals in Korea as a role model. For the getting advanced system of Animation Festivals in Korea. It requires the animation theater for animation, effort for the Audiences's Convenience and international network composition system. However, the last task of us is to make people to entertain and enjoy the animation Films, its world of attraction.

Studies of cold resistant glycine betaine effect on cold sensitive Bacillus subtilis mutant strains (저온 민감성 바실러스 서브틸리스 돌연변이 균주에서 glycine betaine의 저온 내성에 미치는 영향에 대한 연구)

  • Kim, Do Hyung;Lee, Sang Soo
    • Korean Journal of Microbiology
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    • v.54 no.3
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    • pp.200-207
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    • 2018
  • At high salt concentration, glycine betaine is transported into Bacillus subtilis and growing rate of the cell is not suppressed. Also according to recent studies, cell growth is maintained normal growth rate at low temperature. Low temperature results in a stress response of Bacillus subtilis that is characterized by strong repression of major metabolic activities such as translation machinery and membrane transport. In this regards, genes showing cold sensitive phenotype are cold-induced DEAD box RNA helicases (ydbR, yqfR) and fatty acid desaturases (bkdR, des). Therefore to understand the effect of glycine betaine on cold growth of Bacillus subtilis, we investigated the effect of glycine betaine on growth rate of these deletion mutants showing cold sensitive phenotype. Glycine betaine strongly stimulated growth of wild type Bacillus subtilis JH642 and deletion mutants of ydbR and yqfR at $20^{\circ}C$ (190~686 min $T_d$ difference). On the other hands, glycine betaine does not show growth promoting effects on deletion mutants of bkdR, and des at cold conditions. Same cold protectant growth results were shown with the precursor choline instead of glycine betaine. We investigated the effects of detergents on the cell membrane in bkdR and des deficient strains associated with cell membrane. It was identified that bkdR deficient strain shows retarded growth with detergent such as Triton X-100 or N-lauryl sarcosine compared with wild type cell. Thus, it is possible that deletion mutation of bkdR modifies membrane structure and effects on transport of glycine betaine.

The Impact of Mergers on the Experiences of Students (대학 통폐합에 대한 학생들의 적응과정 연구)

  • Chae, Jae-Eun
    • Korean Journal of Comparative Education
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    • v.23 no.5
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    • pp.53-75
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    • 2013
  • This article explores the impact of mergers on the experiences of students. A case design is used to gain an in-depth understanding of the students in a Korean university that was combined with a two-year college in 2007. Semi-structured interviews of 11 direct entrants, 5 transfer students, and 7 professors were conducted in 2010 for the data collection. The results suggest that mergers do not necessarily ensure the integration of the students involved. Since mergers pose enormous challenges to both transfer students and direct entrants, university leaders need to give careful attention to students' persistence and integration as the campus changes. The results also reveal that students' experience of mergers may be affected by cultural backgrounds as well as the hierarchical structure of higher education. In Korean society, where credentialism prevails, mergers can have different impacts on students who come from initial institutions of differing perceived quality, and thus mergers may incite tension among the students. In light of these concerns, this study's findings highlight the importance of student integration as a key element in mergers.

The Effects of Depression, Death Anxiety, and Social Support on Psychological Well-Being of Elderly Living Alone: Mediating Effect of Resilience (우울, 죽음불안, 사회적 지지가 독거노인의 심리적 안녕감에 미치는 영향: 탄력성의 매개효과)

  • Jang, Yeon-Sik;Mo, Seon-Hee
    • 한국노년학
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    • v.37 no.3
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    • pp.527-547
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    • 2017
  • The purpose of this study is to investigate how depression, death anxiety, and social support can exert influence on the psychological well-being of elderly living alone through a parameter of resilience. A survey was conducted involving 988 elderly over the age of 65 living alone in the Daejeon metropolitan area and Chungcheongnam-do and the data were analyzed using structure equation model. The results were as follows. First, in the measurement of variables according to demographic characteristics, depression showed significant differences depending on gender, level of education, health, and financial condition, while death anxiety differed depending on gender, and level of education. Social support was significantly different by gender, age, level of education, region, health, and financial condition. The level of resilience was significantly different by gender, age, level of education, health, and financial condition. Psychological well-being varied according to gender, level of education, health, and financial condition. Second, the effects of depression, death anxiety and social support on psychological well-being were examined. It was found that depression had a negative influence and social support had a positive impact while death anxiety showed no influence. Third, with regard to the effects of depression, death anxiety, social support on resilience, depression was found having negative influence, whereas social support having positive influence. Forth, psychological well-being was positively affected by resilience. Also, through the mediated pathway of resilience, their psychological well-being seemed to totally improve when the negative factors were reduced and the positive ones promoted. This study may have some significance in reference to examine the factors affecting the psychological well-being of elderly living alone and to develop social welfare service programs and policies in the field.

Fabrication of carbon nano tube reinforced grass fiber composite and investigation of fracture surface of reinforced composites (CNT 첨가에 따른 유리섬유/섬유 복합재 제작 및 특성 평가)

  • Kim, Hyeongtae;Lee, Do-Hyeon;An, Woo-Jin;Oh, Chang-Hwan;Je, Yeonjin;Lee, Dong-Park;Cho, Kyuchul;Park, Jun Hong
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.31 no.4
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    • pp.159-165
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    • 2021
  • The fiber composites have been investigated as lightweight structure material platforms for aerospace applications because their strength can be enhanced by adding reinforcement without a significant increase in weight. In this study, the fabrication and characterization of carbon nanotube (CNT) reinforced glass fiber composites are demonstrated to enhance the tensile strength of longitudinal direction along the glass fibers. Due to the reinforcement of CNT in epoxy layers, the yield strength of fiber/epoxy composites is enhanced by about 10 %. Furthermore, using scanning electron microscopy, analysis of fracture surfaces shows that mixed CNT in epoxy layers acts as necking agents between fractured surfaces of fiber/epoxy; thereby, initiation and evolution of crack across fiber composite can be suppressed by CNT necking between fractured surfaces.

A Study on the Meaning of School Space: Criticism and Alternatives (학교 공간에 관한 의미 탐색: 비판과 대안)

  • Kim, Dal-Hyo
    • Journal of the Korean Institute of Educational Facilities
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    • v.26 no.4
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    • pp.3-10
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    • 2019
  • In school facilities, space is the basic framework. The structure and arrangement of space will provide the form and feel of school facilities. In order to become a high-quality school facility, it is necessary to focus on the educational, human and ecological aspects of the instructor and learner until the space is conceived, designed and completed. However, even when public education was introduced in the past, it did not become a school space considering this aspect. The school space, which focuses on efficiency and labor production, is a school space that reflects the characteristics of a factory-type school, which has been occupied by a large number until recently. Although efforts to improve the quality of school facilities have been attempted in recent years, there is also a need to pursue more active changes. Future-oriented and progressive school spaces include flexibility, connectivity, individualization, diversity(creativity). In other words, space should be flexible so that it can be used faithfully according to the educational situation, not the fixed and limited school space as in the past. In the future, the school space should be open and securely linked to the place where it is essential to complete community relations with the community. In addition, space should be flexible so that the school can meet the needs of each student as much as possible. And the school space should be transformed from the space design of the past fixed pattern to reflect the close relationship between spatial, psychological, physiological, and behavioral areas. When school space needs to shift away from the past and change in a new future-oriented direction, the remaining tasks should be presented with specific characteristics and content of the direction. And the function of the consignment should be handled by related research. Although the text of this study reveals the characteristics of future-oriented school space, more concrete and empirical research results should be presented by subsequent research at home and abroad. It is necessary to reduce trial and error in creating a future-oriented school space where both professors and learners can be satisfied by analyzing the common points and differences between the results of the study. In order to do this, it is necessary to make efforts to approach such research based on the participation of the subjects who teach and learn directly at the school site.

Ginseng gintonin alleviates neurological symptoms in the G93A-SOD1 transgenic mouse model of amyotrophic lateral sclerosis through lysophosphatidic acid 1 receptor

  • Nam, Sung Min;Choi, Jong Hee;Choi, Sun-Hye;Cho, Hee-Jung;Cho, Yeon-Jin;Rhim, Hyewhon;Kim, Hyoung-Chun;Cho, Ik-Hyun;Kim, Do-Geun;Nah, Seung-Yeol
    • Journal of Ginseng Research
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    • v.45 no.3
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    • pp.390-400
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    • 2021
  • Background: We recently showed that gintonin, an active ginseng ingredient, exhibits antibrain neurodegenerative disease effects including multiple target mechanisms such as antioxidative stress and antiinflammation via the lysophosphatidic acid (LPA) receptors. Amyotrophic lateral sclerosis (ALS) is a spinal disease characterized by neurodegenerative changes in motor neurons with subsequent skeletal muscle paralysis and death. However, pathophysiological mechanisms of ALS are still elusive, and therapeutic drugs have not yet been developed. We investigate the putative alleviating effects of gintonin in ALS. Methods: The G93A-SOD1 transgenic mouse ALS model was used. Gintonin (50 or 100 mg/kg/day, p.o.) administration started from week seven. We performed histological analyses, immunoblot assays, and behavioral tests. Results: Gintonin extended mouse survival and relieved motor dysfunctions. Histological analyses of spinal cords revealed that gintonin increased the survival of motor neurons, expression of brain-derived neurotrophic factors, choline acetyltransferase, NeuN, and Nissl bodies compared with the vehicle control. Gintonin attenuated elevated spinal NAD(P) quinone oxidoreductase 1 expression and decreased oxidative stress-related ferritin, ionized calcium-binding adapter molecule 1-immunoreactive microglia, S100β-immunoreactive astrocyte, and Olig2-immunoreactive oligodendrocytes compared with the control vehicle. Interestingly, we found that the spinal LPA1 receptor level was decreased, whereas gintonin treatment restored decreased LPA1 receptor expression levels in the G93A-SOD1 transgenic mouse, thereby attenuating neurological symptoms and histological deficits. Conclusion: Gintonin-mediated symptomatic improvements of ALS might be associated with the attenuations of neuronal loss and oxidative stress via the spinal LPA1 receptor regulations. The present results suggest that the spinal LPA1 receptor is engaged in ALS, and gintonin may be useful for relieving ALS symptoms.

Temperature Dependent Creep Properties of Directionally Solidified Ni-based Superlloy CM247LC (일방향 응고 니켈기 초내열 합금 CM247LC의 온도에 따른 크리프 특성)

  • Choi, Baig-Gyu;Do, Jeonghyeon;Jung, Joong Eun;Seok, Woo-Young;Lee, Yu-Hwa;Kim, In Soo
    • Journal of Korea Foundry Society
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    • v.41 no.6
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    • pp.505-515
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    • 2021
  • Creep properties of directionally solidified Ni-based superalloy CM247LC under various temperature and stress conditions have been investigated. In the heat-treated specimen, some portion of eutectic γ-γ' remained, and uniform cubic γ' was observed in the dendrites. At low temperature (750℃) and high stress condition, a large amount of deformation occurred during the primary creep, while the tertiary creep region accounted for most of the creep deformation under high temperature and low stress condition. γ' particles are sheared by dislocation dissociated into super lattice partial dislocations separated by stacking faults at 750℃. No stacking faults in γ' were found at and above 850℃ due to the temperature dependence of the stacking fault energy. Raft structure of γ' was found after creep test at high temperature of 950℃ and 1000℃. At 850℃, the deformation mechanism was shown to be dependent on the stress condition, and so rafting was observed only under low stress condition.

The Relationship among Leisure Experience, Exercise flow Adherence of Senior in Fitness Center (스포츠센터 노인 운동 프로그램 참여자의 여가경험과 여가몰입 및 운동만족의 관계)

  • Lee, Seung-Bum
    • Journal of Korea Entertainment Industry Association
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    • v.15 no.2
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    • pp.159-167
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    • 2021
  • The main purpose of this study is to closely investigate the constructive relationship between leisure satisfaction, leisure ability, exercise satisfaction, and consistent motor behavior patterns of the elderly's participation in leisure life sports. In order to achieve this, we surveyed and utilized the sampling of conveniences that selected Yongin and Seongnam city in Gyeonggi-do sports clubs, and accumulated samples of the elderly in living sports. The sample size was 239 elderly people. Based on this, according to the purpose of the study, statistical techniques, spss 23.0, and amos programs were used for analysis. The satisfaction analysis used in the research for a data analysis includes frequency analysis, exploatory factor analysis, confirmatory facor analysis, reliability analysis, correnlation analysis and structure equation model analysis. The research has drawn the following conclusions, based on the above mentioned research method and its procedures: First, it affects the satisfaction of the leisure satisfaction movement. Second, leisure ability affects exercise satisfaction. Third, exercise satisfaction affects the consistent exercise persistence and immersion satisfaction of exercise. As a result, it can be seen that the leisure immersion according to the experience of leisure competence has an effect on the satisfaction of the exercise. As a result, and the continuation of the exercise.