• 한국전문물리치료학회지
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• 제22권3호
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• pp.98-105
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• 2015

Muscular dystrophy is a hereditary musculoskeletal disorder caused by a mutation in the dystrophin gene. Duchenne muscular dystrophy (DMD) is one of the most common, and progresses relatively faster than other muscular dystrophies. It is characterized by progressive myofiber degeneration, muscle weakness and ultimately ambulatory loss. Since it is an X-linked recessive inheritance, DMD is mostly expressed in males and rarely expressed or less severe in females. The most effective measurement tool for DMD is magnetic resonance imaging (MRI), which allows non-invasive examination of longitudinal measurement. It can detect progressive decline of skeletal muscle size by measuring a maximal cross-sectional area of skeletal muscle. Additionally, other techniques in MRI, like $T_2$-weighted imaging, assess muscle damage, including inflammation, by detecting changes in $T_2$ relaxation time. Current MRI techniques even allow quantification of metabolic differences between affected and non-affected muscles in DMD. There is no current cure, but physical therapist can improve their quality of life by maintaining muscle strength and function, especially if treatment (and other forms of medical intervention) begins in the early stages of the disease.

• Journal of the Optical Society of Korea
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• 제16권1호
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• pp.42-46
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• 2012

We have developed a fluorescence optical detection system using a digital micromirror device (DMD) for monitoring 3D cell culture matrices in situ. Full 3D imaging with fast scanning speed was implemented by the combined action of a DMD and a motorized stage. Imaging results with fluorescent microbeads measure the minimum axial resolution of the system as $6.3{\mu}m$, while full 1-mm scanning through 3D alginate-based matrix was demonstrated. For cell imaging, improved images were obtained by removing background fluorescence although the scanning distance was reduced because of low intracellular fluorescence efficiency. The system is expected to be useful to study various dynamics and behaviors of 3-dimensionally cultured cells in microfluidic systems.

• 한국광학회지
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• 제20권1호
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• pp.23-28
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• 2009

본 논문에서는 대면적 리소그래피를 위하여 홀로그램 영상을 연결하여 기록 물질에 저장하고 이를 마스크로 이용하는 노광 방법을 제안하고 구현하였으며, 홀로그램 영상을 재생하는 과정에서 발생되는 영상 연결 부분에서의 간섭 무늬를 제거하였다. 연결하고자 하는 영상은 DMD(digital micro-mirror device)로 표시하였으며, DMD 영상은 축소 광학계를 통하여 기록 물질에 저장되었다. 기록 물질은 전동 스테이지로 이동되도록 하여, DMD로 표시되는 영상이 기록 물질에 연속적으로 저장되도록 하였다. 이러한 방법으로 저장되는 연결된 영상은 재생광에 의하여 노광에 사용되는데, 재생광의 간섭성에 의하여 연결부분에 간섭무늬가 발생된다. 간섭무늬는 노이즈로 작용하는데, 다중 노광에 의한 홀로그램 영상의 기록과 재생을 이용하여 이를 제거하였다. 본 논문에서는 DMD와 전동 스테이지를 이용하여 영상을 연결하여 기록하고, 다중 노광에 의한 영상 기록 방법을 이용하여, 간섭 무늬가 제거된 연결된 영상을 구현하고 이를 리소그래피에 적용하였다.

• 한국레이저가공학회:학술대회논문집
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• 한국레이저가공학회 2005년도 추계학술발표대회 논문집
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• pp.37-41
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• 2005

When screen size of the Flat Panel Display (FPD) becomes larger, the traditional photo-lithography using photomasks and UV lamps might not be possible to make patterns on Photo Resist (PR) material due to limitation of the mask size. Though the maskless photo-lithography using UV lasers and scanners had been developed to implement large screen display, it was very slow to apply the process for mass-production systems. The laser exposure system using 405 nm semi-conductor lasers and Digital Micromirror Devices (DMD) has been developed to overcome above-mentioned problems and make more than 100 inches FPD devices. It makes very fine patterns for full HD display and exposes them very fast. The optical engines which contain DMD, Micro Lens Array (MLA) and projection lenses are designed for 10 to 50 ${\mu}m$ bitmap pattern resolutions. The test patterns for LCD and PDP displays are exposed on PR and Dry Film Resists (DFR) which are coated or laminated on some specific substrates and developed. The fabricated edges of the sample patterns are well-defined and the results are satisfied with tight manufacturing requirements.

• 한국산학기술학회논문지
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• 제12권2호
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• pp.829-834
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• 2011

고 집적 회로의 제작에 있어서 노광 공정은 가장 중요한 기술로 주로 마스크 방식의 노광 방법을 사용하지만 다품종 소량 생산 및 주기적인 제품 변화에 있어서 효율적이지 못하기 때문에 마스크리스 리소그래피 기술이 노광공정에서 각광받고 있다. 본 연구에서는 DMD를 이용한 마스크리스 리소그래피에 있어 다중 레이저 빔의 에너지와 중첩도와의 연관성을 시뮬레이션을 통해 분석하였다. 시뮬레이션을 통해 최적의 스캔 라인 간격을 제시하였고, LDI 시스템을 이용한 노광 실험을 통해 미세 페턴의 정밀도를 향상시킬 수 있었다.

• Imaging Science in Dentistry
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• 제46권4호
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• pp.279-284
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• 2016

To our knowledge, the imaging features of costochondral grafts (CCGs) on cone-beam computed tomography (CBCT) have not been documented in the literature. We present the case of a CCG in the facial soft tissue to the anterior mandible, with changes mimicking a cartilaginous neoplasm. This is the first report to describe the CBCT imaging features of a long-standing graft in the anterior mandible. Implants or grafts may be incidental findings on radiographic images made for unrelated purposes. Although most are well-defined and radiographically homogeneous, being of relatively inert non-biological material, immune reactions to some grafts may stimulate alterations in the appearance of surrounding tissues. Biological implants may undergo growth and differentiation, causing their appearance to mimic neoplastic lesions. We present the case of a cosmetic autogenous CCG that posed a diagnostic challenge both radiographically and histopathologically.

• Journal of the Optical Society of Korea
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• 제18권2호
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• pp.146-150
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• 2014

We propose an experimental holographic imaging scheme combining compressive sensing (CS) theory with digital holography in phase-shifting conditions. We use the Mach-Zehnder interferometer for hologram formation, and apply the compressive sensing (CS) approach to the holography acquisition process. Through projecting the hologram pattern into a digital micro-mirror device (DMD), finally we will acquire the compressive sensing measurements using a photodiode. After receiving the data of two holograms via conventional communication channel, we reconstruct the original object using certain signal recovery algorithms of CS theory and hologram reconstruction techniques, which demonstrated the feasibility of the proposed method.

• Imaging Science in Dentistry
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• 제51권2호
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• pp.209-216
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• 2021

Sjögren syndrome is a chronic autoimmune inflammatory disease characterized by lymphocytic infiltration of exocrine glands, predominantly the parotid and lacrimal glands, thereby resulting in oral and ocular dryness. It has been reported to occur most frequently in women between 40 and 50 years of age. Sjögren syndrome has an insidious onset, is slowly progressive, and presents a wide range of clinical manifestations, leading to delays or challenges in the diagnosis. Early diagnosis of this condition is essential to prevent the associated complications that affect patients' quality of life. This report presents 3 cases of Sjögren syndrome in female patients aged between 40 and 75 years who presented with complaints of persistent dry mouth and burning sensation. The cases highlight the diagnostic value of 3-dimensional cone-beam computed tomographic sialography in the detection of salivary gland pathologies at an early stage.

• 한국생산제조학회지
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• 제19권6호
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• pp.834-840
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• 2010

Photo lithography process is very important technology to fabricate highly integrated micro patterns with high precision for semiconductor and display industries. Up to now, mask type lithography process has been generally used for this purpose; however, it is not efficient for small quantity and/or frequently changing products. Therefore, in order to obtain higher productivity and lower manufacturing cost, the mask type lithography process should be replaced. In this study, a maskless lithography system using the DMD(Digital Micromirror Device) is developed, and the exposure condition and optical properties are analyzed and simulated for a single beam case. From the proposed experimental conditions, required exposure experiments were preformed, and the results were investigated. As a results, 10${\mu}m$ spots can be generated at optimal focal length.

• Journal of Oral Medicine and Pain
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• 제45권4호
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• pp.97-109
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• 2020

Purpose: Cervicogenic headache (CGH) is pain referred to the head/ face from the structures in vicinity of upper cervical spinal nerves via trigeminocervical pathway. Ponticulus Posticus (PP) and Elongated Styloid Process (ESP) are anatomical structures that cause compression of vasculature present around upper cervical nerve plexus. Recently, computational fluid dynamics (CFD) has shown to play an essential role in identification of these high-pressure zones in the brain. The aim of this research is to study the association of ESP and PP in patients with CGH and to develop a hypothesis by CFD to analyse vertebrobasilar insufficiency as a contributing factor in occurrence of CGH. Methods: Retrospective analysis of 4500 full skull CBCT scans was done for the presence of partial or complete PP and length of Styloid Process (SP). Research was divided into two phases; In first Preliminary Phase, 150 scans that showed the presence of PP and ESP were analysed, and only 134 patients gave consent to fill the questionnaire containing 96 question items pertaining to symptoms associated with CGH. In the second phase, simulation of Vertebral and Carotid Artery was done using Fluent 14.5 Software and by CFD, pressure distribution on arteries was obtained that helped to identify high pressure regions. Results: Both PP and ESP showed a statistically significant association with CGH (p<0.001). By CFD analysis, both steady and transient phases of simulation showed drop in pressure due to constriction of internal carotid and vertebral artery by ESP and PP respectively and were found to decrease the volume of blood reaching the brain, 0.12 /0.13 mL and 0.06 mL respectively. Conclusions: Our analysis proves ESP and PP as contributing factors towards CGH. Hence for proper diagnosis and management of headache disorders, clinicians should have adequate knowledge about these anatomical structures and their resulting clinical symptoms.