• Korean Journal of Plant Resources
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• v.30 no.6
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• pp.640-646
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• 2017

In this study, we elucidated anti-cancer activity and potential molecular mechanism of 70% ethanol extracts from Taxilli Ramulus (Taxillus chinensis (DC.) Danser) (TR-E70) against human colorectal cancer cells. Anti-cell proliferative effect of TR-E70 was evaluated by MTT assay. The effect of TR-E70 on the expression of cyclin D1 in the protein and mRNA level was evaluated by Western blot and RT-PCR, respectively. TR-E70 suppressed the proliferation of human colorectal cancer cell lines, HCT116 and SW480. Although TR-E70 decreased cyclin D1 expression in protein and mRNA level, decreased level of cyclin D1 protein by TR-E70 more dramatically occurred than that of cyclin D1 mRNA. Cyclin D1 downregulation by TR-E70 was attenuated in presence of MG132. In addition, TR-E70 phosphorylated threonine-286 (T286) of cyclin D1. TR-E70-mediated cyclin D1 degradation was blocked in presence of LiCl as an inhibitor $GSK3{\beta}$ but not PD98059 as an ERK1/2 inhibitor and SB203580 as a p38 inhibitor. Our results suggest that TR-E70 may downregulate cyclin D1 as one of the potential anti-cancer targets through $GSK3{\beta}$-dependent cyclin D1 degradation. From these findings, TR-E70 has potential to be a candidate for the development of chemoprevention or therapeutic agents for human colorectal cancer.

• Journal of Power Electronics
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• v.17 no.2
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• pp.570-578
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• 2017

This paper proposes a method to stabilize the output voltage of the secondary side of an Inductive Power Transfer (IPT) system through tuning/detuning via a serial tuned DC Voltage-controlled Variable Capacitor (DVVC). The equivalent capacitance of the DVVC changes with the conduction period of a diode in the DVVC controlled by DC voltage. The output voltage of an IPT system can be made constant when this DVVC is used as a variable resonant capacitor combined with a PI controller generating DC control voltage according to the fluctuations of the output voltage. Since a passive diode instead of an active switch is used in the DVVC, there are no active switch driving problems such as a separate voltage source or gate drivers, which makes the DVVC especially advantageous when used at the secondary side of an IPT system. Moreover, since the equivalent capacitance of the DVVC can be controlled smoothly with a DC voltage and the passive diode generates less EMI than active switches, the DVVC has the potential to be used at much higher frequencies than traditional switch mode capacitors.

• The Transactions of the Korean Institute of Electrical Engineers A
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• v.54 no.9
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• pp.427-433
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• 2005

In DC tracking power supply system, ground faults are currently detected by the potential relay, 64P. Though 64P relay detects ground fault, it cannot Identify the faulted region which causes long traffic delays and safety problem to passengers. Two new ground fault protective relay schemes that can identify the faulted region are presented in this paper. One is bus differential protective relay and the other is ground overcurrent protective relay. Both type of relays is similar in principle to the ordinary bus differential protective relay and the ground overcurrent relay used in other power system. In DC traction power supply system, since it is ungrounded, ground fault current is not big enough to operate those relays. To solve the problem, a current control device, called device 'X', is newly introduced in both system, which enables large amount of ground fault current flow upon the positive line to ground fault. Algorithms for these relays are developed and their validity are verified by EMTP simulation.

• Journal of Electrical Engineering and Technology
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• v.13 no.2
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• pp.781-789
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• 2018

This paper proposes a new approach utilizing empirical mode decomposition (EMD) reconstruction to process vibration signals of a transformer under DC bias caused by high voltage direction transmission (HVDC), which is the potential cause of additional vibration and noise from transformer. Firstly, the Calculation Method is presented and a 3D model of transformer is simulated to analyze transformer deformation characteristic and the result indicate the main vibration is produced along axial direction of three core limbs. Vibration test system has been built and test points on the core and shell of transformer have been measured. Then, the signal reconstruction method for transformer vibration based on EMD is proposed. Through the EMD decomposition, the corrupted noise can be selectively reconstructed by the certain frequency IMFs and better vibration signals of transformer have been obtained. After EMD reconstruction, the vibrations are compared between transformer in normal work and with DC bias. When DC bias occurs, odd harmonics, vibration of core and shell, behave as a nonlinear increase and the even harmonics keep unchanged with DC current. Experiment results are provided to collaborate our theoretical analysis and to illustrate the effectiveness of the proposed EMD method.

• The Transactions of the Korean Institute of Power Electronics
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• v.3 no.3
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• pp.231-239
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• 1998

This paper presents the dynamic analysis and control loop design of a zero voltage switching full bridge (ZVS-FB) PWM DC/DC converter. The small-signal model is derived incorporating the effects of phase shift control and the utilization of transformer leakage inductance and power FET junction capacitance to achieve zero voltage resonant switching. These effects are modeled by introducing additional feedforward and feedback terms for duty cycle modulation. Based on the results of the small-signal analysis, the control loop is designed using a simple two-pole one-zero compensation circuit. To show the validity of the design procedures, the small signal analysis of the closed loop system is carried out and the potential of the zero voltage switching and the superiority of the dynamic characteristics are verified through the experiment with a 2 kW prototype converter.

• Journal of the Korean institute of surface engineering
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• v.42 no.3
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• pp.133-138
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• 2009

Effects of bipolar pulse driving frequency between 50 kHz and 250 kHz on the discharge shapes were analyzed by measuring plasma characteristics by OES (Optical Emission Spectroscopy) and Langmuir probe. Plasma characteristics were modeled by a simple electric field analysis and fluid plasma modeling. Discharge shapes by a continuous dc and bipolar pulsed dc were different as a dome-type and a vertical column-type at the cathode. From OES, the intensity of 811.5 nm wavelength, the one of the main peaks of Ar, decreased to about 43% from a continuous dc to 100 kHz. For increasing from 100 kHz to 250 kHz, the intensity of 811.5 nm wavelength also decreased by 46%. The electron density decreased by 74% and the electron temperature increased by 36% at the specific position due to the smaller and denser discharge shape for increasing pulse frequency. Through the numerical analysis, the negative glow shape of a continuous dc were similar to the electric potential distribution by FEM (Finite Element Method). For the bipolar pulsed dc, we found that the electron temperature increased to maximum 10 eV due to the voltage spikes by the fast electron acceleration generated in pre-sheath. This may induce the electrons and ions from plasma to increase the energetic substrate bombardment for the dense thin film growth.

• Progress in Superconductivity and Cryogenics
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• v.5 no.1
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• pp.56-59
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• 2003

As electric power systems grow to supply the increasing electric power demand short-circuit current tends to increase and impose a severe burden on circuit breakers and power system apparatuses. Thus, all electric equipment in a power system has to he designed to withstand the mechanical and thermal stresses of potential short-circuit currents. Among current limiting devices, Fault Current Limiter (FCL) is expected to reduce the short-circuit current. Especially, Superconducting Fault Current Limiters (SFCL) offer ideal performance: in normal operation the SFCL is in its superconducting state and has negligible impedance, in the event of a fault, the transition into the normal conducting state passively limits the current. The SFCL using high-temperature superconductors offers a positive resolution to controlling fault-current levels on utility distribution and transmission networks. This study contributes to the EMTDC based modeling and simulation method of DC Reactor type SFCL. Single and three phase faults in the utility system with DC reactor type SFCLs have been simulated using EMTDC in order to coordinate with other equipments, and the results are discussed in detail.

• Proceedings of the KIEE Conference
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• 2001.07b
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• pp.843-845
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• 2001

In this paper, we analyze the characteristics of electecromotive force(emf), phase current and torque according to the length of the air gap using 2nd order FEM(Finite Element Method) in Synchronous Reluctance Motor(SRH) and Brushless DC Motor(BLDC) with same volume and size. In the analysis with FEM, we applied the time-step function considering the motor switch in the magnetic vector potential of the unknown node.

• 제어로봇시스템학회:학술대회논문집
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• 2005.06a
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• pp.813-816
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• 2005

This paper presents a method for harmonic elimination and reactive power compensation using an intervening firing method and passive power filter with is suitable to compensate rapidly changing loads and reactive power. The proliferation of three-phase thyristor phase-controlled converter of DC motor drives into a power system has the potential to increase the harmonic levels in the power system. The design procedure of an intervening firing method and passive power filter capable of reducing the voltage and current harmonics produced by converter supplied from a source having internal large inductive impedance is offered. The analysis uses the or CAD PSpice to model three-phase thyristor phase-controlled converter of DC motor drives as well as the system.

• Proceeding of EDISON Challenge
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• 2014.03a
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• pp.115-125
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• 2014

We investigate dissociation of diatomic molecules and anions using density functional theory (DFT) and density-corrected density functional theory (DC-DFT). We scan the potential energy curve of CH, NH and NO neutral molecule and its anion with both DFT and DC-DFT (in form of Hartree-Fock DFT, HF-DFT) using various functionals. Using CCSD(T) results as reference, we perform the error decomposition scheme recently proposed by Kim et al. The results show while most neutrals are $functio{\acute{n}}al$ error $domi{\bar{n}}ating$ normal calculations, $CH^-$ and $NO^-$ anions are density-driven error dominating abnormal calculations. In case of $NH^-$, traditional DFT goes to a wrong dissociation limit indicating abnormality, but both HF-DFT and CCSD(T) results need further investigation due to the kinks on the curve.