• Title/Summary/Keyword: D1/D2 domain

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A Study on Effect of Domain-Decomposition Method on Parallel Efficiency in 2-D Flow Computations (2차원 유동장 해석에서 영역분할법에 따른 병렬효율성 검토)

  • Lee Sangyeul;Hur Nahmkeon
    • 한국전산유체공학회:학술대회논문집
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    • 1998.11a
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    • pp.147-152
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    • 1998
  • 2-D flow fields are studied by using a shared memory parallel computer with a parallel flow analysis program which uses domain decomposition method and MPI library for data exchange at overlapped interface. Especially, effects of directional domain decomposition on parallel efficiency are studied for 2-D Lid-Driven cavity flow and flow through square cavity. It is known from the present study that domain decomposition along the main flow direction gives better parallel efficiency in 1-D partitioning than along the other direction. 2-D partitioning, however, is less sensitive to flow directions and gives good parallel efficiency for most of the cases considered.

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Replacement of the antifreeze-like domain of human N-acetylneuraminic acid phosphate synthase with the mouse antifreeze-like domain impacts both N-acetylneuraminic acid 9-phosphate synthase and 2-keto-3-deoxy-D-glycero-Dgalacto- nonulosonic acid 9-phosphate synthase activities

  • Reaves, Marshall Louis;Lopez, Linda Carolyn;Daskalova, Sasha Milcheva
    • BMB Reports
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    • v.41 no.1
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    • pp.72-78
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    • 2008
  • Human NeuNAc-9-P synthase is a two-domain protein with ability to synthesize both NeuNAc-9-P and KDN-9-P. Its mouse counterpart differs by only 20 out of 359 amino acids but does not produce KDN-9-P. By replacing the AFL domain of the human NeuNAc-9-P synthase which accommodates 12 of these differences, with the mouse AFL domain we examined its importance for the secondary KDN-9-P synthetic activity. The chimeric protein retained almost half of the ability of the human enzyme for KDN-9-P synthesis while the NeuNAc-9-P production was reduced to less than 10%. Data from the homology modeling and the effect of divalent ions and temperature on the enzyme activities suggest conformational differences between the human and mouse AFL domains that alter the shape of the cavity accommodating the substrates. Therefore, although the AFL domain itself does not define the ability of the human enzyme for KDN-9-P synthesis, it is important for both activities by aiding optimal positioning of the substrates.

t-LINKED OVERRINGS OF A NOETHERIAN DOMAIN

  • Chang, Gyu-Whan
    • Korean Journal of Mathematics
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    • v.7 no.2
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    • pp.167-169
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    • 1999
  • Let R be a Noetherian domain. It is proved that $t$-dimR = 1 if and only if each (proper if R is not a valuation domain) $t$-linked overring D of R is of $t$-dimD = 1 if and only if each integrally closed $t$-linked overring of R is a Krull domain.

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Molecular and Structural Characterization of the Domain 2 of Hepatitis C Virus Non-structural Protein 5A

  • Liang, Yu;Kang, Cong Bao;Yoon, Ho Sup
    • Molecules and Cells
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    • v.22 no.1
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    • pp.13-20
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    • 2006
  • Hepatitis C virus (HCV) non-structural protein 5A protein (NS5A), which consists of three functional domains, is involved in regulating viral replication, interferon resistance, and apoptosis. Recently, the three-dimensional structure of the domain 1 was determined. However, currently the molecular basis for the domains 2 and 3 of HCV NS5A is yet to be defined. Toward this end, we expressed, purified the domain 2 of the NS5A (NS5A-D2), and then performed biochemical and structural studies. The purified domain 2 was active and was able to bind NS5B and PKR, biological partners of NS5A. The results from gel filtration, CD analysis, 1D $^1H$ NMR and 2D $^1H-^{15}N$ heteronuclear single quantum correlation (HSQC) spectroscopy indicate that the domain 2 of NS5A appears to be flexible and disordered.

ON STABILITY OF A TRANSFMISSION PROBLEM

  • Kang, Hyeon-Bae;Seo, Jin-Keun
    • Journal of the Korean Mathematical Society
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    • v.34 no.3
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    • pp.695-706
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    • 1997
  • We investigate the bahivor of the gradient of solutions to the refraction equation $div(( 1+ (k - 1)_\chi D)\nabla u) = 0$ under perturbation of domain D. If $u_h$ are solutions to the refraction equation corresponding to subdomains D and $D_h$ of a domain $\Omega$ in 2 dimensional plane with the same Neumann data on $\partial\Omega$, respectively, we prove that $\left\$\mid$ \nabla(u - u_h) \right\$\mid$_{L^2(\Omega)} \leq C\sqrt{dist(D, D_h)}$ where $dist(D, D_h)$ is the Hausdorff distance between D and $D_h$. We also show that this is the best possible result.

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Crystal Structure of p97 N-D1 Hexamer in Complex with p47 UBX Domain

  • Thang Quyet Nguyen;Wonchull Kang
    • Journal of the Korean Chemical Society
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    • v.68 no.1
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    • pp.25-31
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    • 2024
  • The p97 adenosine triphosphatase is a key player in protein homeostasis, responsible for unfolding ubiquitylated substrates. It engages with various adaptor proteins through its N-terminal domain, with the p97-p47 complex attracting particular attention for its involvement in membrane remodeling. Although the structures of p97 in complex with the Ubiquitin regulatory X (UBX) domain from various adaptors have been reported, the stoichiometry is conflicting. Here, we report the crystal structure of the p97 N-D1 hexamer in complex with the p47 UBX domain at a resolution of 2.7 Å. The structure reveals a stoichiometry of 6:6 between the p97 N-D1 and the p47 UBX domain. These findings provide valuable insights into the binding stoichiometry of p97 N-D1 and p47 UBX domain, which are crucial for understanding the role of p97 and adaptor proteins in cellular processes such as the ubiquitin-proteasome pathway, membrane fusion, and cell cycle regulation.

HARMONIC DOUBLING CONDITION AND JOHN DISKS

  • Kim, Ki-Won
    • Communications of the Korean Mathematical Society
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    • v.10 no.1
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    • pp.145-153
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    • 1995
  • A Jordan domain D in C is said to be a c-quasidisk if there exists a constant $c \geq 1$ such that each two points $z_1$ and $z_2$ in D can be joined by an arc $\tau$ in D such that $$ \ell(\tau) \leq c$\mid$z_1 - z_2$\mid$ $$ and $$ (1.1) min(\ell(\tau_1),\ell(\tau_2)) \leq c d(z, \partial D) $$ for all $z \in \tau$, where $\tau_1$ and $\tau_2$ are the components of $\tau\{z}$. Quasidisks have been extensively studied and can be characterized in many different ways [1],[2],[3].

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WEAKLY KRULL AND RELATED PULLBACK DOMAINS

  • Chang, Gyu-Whan
    • The Pure and Applied Mathematics
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    • v.11 no.2
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    • pp.117-125
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    • 2004
  • Let T be an integral domain, M a nonzero maximal ideal of T, K = T/M, $\psi$: T \longrightarrow K the canonical map, D a proper subring of K, and R = $\psi^{-1}$(D) the pullback domain. Assume that for each $x \; \in T$, there is a $u \; \in T$ such that u is a unit in T and $ux \; \in R$, . In this paper, we show that R is a weakly Krull domain (resp., GWFD, AWFD, WFD) if and only if htM = 1, D is a field, and T is a weakly Krull domain (resp., GWFD, AWFD, WFD).

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Polygon-shaped Filters in Frequency Domain for Practical Filtering of Images (현실적 영상 필터링 방법을 위한 주파수 영역에서의 다각형 형태 필터의 모델링)

  • Kim, Ju-O;Kim, Ji-Su;Park, Cheol-Hyeong;Lee, Deok-Woo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.3
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    • pp.1-7
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    • 2019
  • In this paper, we propose an approach to design a practical filter and a mathematical modeling for images. In the areas of signal processing, including high-dimensional image processing, the filtering process has been fundamental and crucial in diverse practical applications such as image processing, computer vision, and pattern recognition. In general, the ideal filter is modeled as circular-shaped in the 2D frequency domain as the rectangular shape is ideal for the 1D frequency domain. This paper proposes an approach to modeling practical and efficient image filter in the 2D frequency domain. Instead of employing a circular-shaped filter, this study proposes a polygon-shaped filter inspired by the concept of a hexagon cellular system for frequency reuse in wireless communication systems. By employing the concept of frequency reuse, bandwidth efficiency is also achieved in the frequency domain. To substantiate the proposed approach, quantitative evaluation is performed using PSNR.

Design of Standard Model for 3D Cadastre System Development (3D 지적시스템 개발을 위한 표준모델 설계)

  • Jung, Young-Jin;Kwak, Byung-Yong;Koh, June-Hwan
    • Journal of Cadastre & Land InformatiX
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    • v.45 no.1
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    • pp.193-205
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    • 2015
  • The existing 2D cadastre as the core engine of land administration systems met with the difficulty of managing and representing the real 3D world. As a result, a 3D cadastre system has emerged as a solution oriented towards managing, representing and providing 3D spatial information related to physical status, land rights, restrictions and responsibilities. The aim of this study is to establish the foundation of the 3D cadastre information system. With this in mind, this paper aims not only to set up the data range of the 3D cadastre, but also to design a conceptual model based on an LADM (Land Administration Domain Model) through the investigation of legal restrictions and land uses relating to spaces in 3D.