• Korean Journal of Mathematics
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• 제19권4호
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• pp.343-349
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• 2011

Let D be an integral domain, $D^w$ be the $w$-integral closure of D, X be an indeterminate over D, and $N_v=\{f{\in}D[X]{\mid}c(f)_v=D\}$. In this paper, we introduce the concept of $t$-locally APVD. We show that D is a $t$-locally APVD and a UMT-domain if and only if D is a $t$-locally APVD and $D^w$ is a $PvMD$, if and only if D[X] is a $t$-locally APVD, if and only if $D[X]_{N_v}$ is a locally APVD.

• Investigative Magnetic Resonance Imaging
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• 제22권2호
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• pp.86-93
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• 2018

Purpose: Imaging plays a significant role in diagnosing leptomeningeal metastases. However, the most appropriate sequence for the detection of leptomeningeal metastases has yet to be determined. This study compares the efficacies of contrast-enhanced T2 fluid attenuated inversion recovery (FLAIR) and contrast-enhanced 3D T1 black-blood fast spin echo (FSE) imaging for the detection of leptomeningeal metastases. Materials and Methods: Tube phantoms containing varying concentrations of gadobutrol solution were scanned using T2 FLAIR and 3D T1 black-blood FSE. Additionally, 30 patients with leptomeningeal metastases were retrospectively evaluated to compare conspicuous lesions and the extent of leptomeningeal metastases detected by T2 FLAIR and 3D T1 black-blood FSE. Results: The signal intensities of low-concentration gadobutrol solutions (< 0.5 mmol/L) on T2 FLAIR images were higher than in 3D T1 black-blood FSE. The T2 FLAIR sequences exhibited significantly greater visual conspicuity scores than the 3D T1 black-blood sequence in leptomeningeal metastases of the pial membrane of cistern (P = 0.014). T2 FLAIR images exhibited a greater or equal extent (96.7%) of leptomeningeal metastases than 3D T1 black-blood FSE images. Conclusion: Because of its high sensitivity even at low gadolinium concentrations, contrast-enhanced T2 FLAIR images delineated leptomeningeal metastases in a wider territory than 3D T1 black-blood FSE.

• 한국자기공명학회:학술대회논문집
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• 한국자기공명학회 2002년도 제20회 학술발표회
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• pp.23-23
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• 2002

• Journal of Microbiology and Biotechnology
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• 제16권10호
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• pp.1529-1536
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• 2006

We cloned a gene of ompH(D:4) from pigs infected with P. multocida D:4 in Korea [16]. The gene is composed of 1,026 nucleotides coding 342 amino acids (aa) with a signal peptide of 20 aa (GenBank accession number AY603962). In this study, we analyzed the ability of the ompH(D:4) to induce protective immunity against a wild-type challenge in mice. To determine appropriate epitope(s) of the gene, one full and three different types of truncated genes of the ompH(D:4) were constructed by PCR using pET32a or pRSET B as vectors. They were named ompH(D:4)-F (1,026 bp [1-1026] encoding 342 aa), ompH(D:4)-t1 (693 bp [55-747] encoding 231 aa), ompH(D:4)-t2 (561 bp [187-747] encoding 187 aa), and ompH(D:4)-t3 (540 bp [487-1026] encoding 180 aa), respectively. The genes were successfully expressed in Escherichia coli BL21(DE3). Their gene products, polypeptides, OmpH(D:4)-F, -t1, -t2, and -t3, were purified individually using nickel-nitrilotriacetic acid (Ni-NTA) affinity column chromatography. Their $M_rs$ were determined to be 54.6, 29, 24, and 23.2 kDa, respectively, using SDS-PAGE. Antisera against the four kinds of polypeptides were generated in mice for protective immunity analyses. Some $50{\mu}g$ of the four kinds of polypeptides were individually provided intraperitoneally with mice (n=20) as immunogens. The titer of post-immunized antiserum revealed that it grew remarkably compared with pre-antiserum. The lethal dose of the wild-type pathogen was determined at $10{\mu}l$ of live P. multocida D:4 through direct intraperitoneal (IP) injection, into post-immune mice (n=5, three times). Some thirty days later, the lethal dose ($10{\mu}l$) of live pathogen was challenged into the immunized mouse groups [OmpH(D:4)-F, -t1, -t2, and -t3; n=20 each, two times] as well as positive and negative control groups. As compared within samples, the OmpH(D:4)-F-immunized groups showed lower immune ability than the OmpH(D:4)-t1, -t2, and -t3. The results show that the truncated-OmpH(D:4)-t1, -t2, and -t3 can be used for an effective vaccine candidate against swine atrophic rhinitis caused by pathogenic P. multocida (D:4) isolated in Korea.

• 대한화학회지
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• 제33권4호
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• pp.431-435
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• 1989

완전히 불순물을 제거한 투명한 polymethylmethacrylate(PMMA)의 prerod를 제조하여 연속 열연신하여 얻은 플라스틱 섬유의 연신온도($T_d$)에 따른 굴절율, 굴절율분포, 복굴절율 및 전송손실율을 측정하였다. $T_d$가 높을수록 다소 낮은 굴절율을 보였으나, 섬유의 중심에서 주변으로 감에 따른 굴절율분포는 오히려 낮은 $T_d$에서가 현저했고, 높은 $T_d$에서는 주변에서만 급격한 굴절율의 강하를 보였다. 또한 $T_d$가 220$^{\circ}C$ 미만에서는 복굴절을 ${\Delta}$n = $5{sim}6{\times}10^{-4}$을 보이고 그 보다 높은 온도의 $T_d$에서는 이러한 현상이 나타나지 않았다. Attenuation은 높은 $T_d$일수록 낮은 값을 보였다.

• 대한수학회보
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• 제44권4호
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• pp.731-742
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• 2007

Let X be a Banach space, $A:D(A){\subset}X{\rightarrow}X$ the generator of a compact $C_0-semigroup\;S(t):X{\rightarrow}X,\;t{\geq}0$, D a locally closed subset in X, and $f:(a,b){\times}C([-q,0];X){\rightarrow}X$ a function of Caratheodory type. The main result of this paper is that a necessary and sufficient condition in order that D be a viable domain of the semi linear differential equation of retarded type $$u#(t)=Au(t)+f(t,u_t),\;t{\in}[t_0,\;t_0+T],{u_t}_0={\phi}{\in}C([-q,0];X)$$ is the tangency condition $$\limits_{h{\downarrow}0}^{lim\;inf\;h^{-1}d(S(h)v(0)+hf(t,v);D)=0}$$ for almost every $t{\in}(a,b)$ and every $v{\in}C([-q,0];X)\;with\;v(0){\in}D$.

• KSBB Journal
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• 제14권2호
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• pp.235-240
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• 1999

Trigonopsis variabilis ATCC10679 (TW)의 변이균주를 선별하기 위하여 쉽고 간편한 균주 선별방법을 개발하였다. 변이 균주(T26)의 D-Amino acid oxidase (D-AAO)는 야생균주(TW)의 D-AAO 효소보다 cephalosporin C에 대한 기질특이성이 약 30% 높았다. 이들 두 균주에서 D-AAO 유전자를 클로닝하여 각 유전자를 비교해본 결과 811번 우치의 T가 C로 변경되었으며 이에 따른 아미노산은 Phe-258이 Ser-258로 바뀌었다.

• Investigative Magnetic Resonance Imaging
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• 제11권2호
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• pp.87-94
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• 2007

목적: 3T 장비의 신생아 뇌자기공명영상에서 T1 강조 고속 역전회복기법 (fast inversion recovery, FIR)과 자기화 삼차원 경사에코기법, (magnetization-prepared three dimensional gradient echo sequence, 3D GRE)을 스핀에코기법 (SE)과 비교하여 유용성을 알아보는 데 있다. 대상 및 방법: 20명의 신생아에서 T1 강조 SE, FIR, 그리고 3D GRE의 신호소음비 (SNR)와 대조소음비 (CNR)를 측정하고 시각적으로 회백질-백질 구별, 수초화 인식, 인공음영 발생을 점수화하여 비교하였다. 각 영상기법의 CNR 비교에는 Wilcoxon signed ranked test를 사용하였다. 결과: 세가지 영상기법 중 3D GRE가 가장 우수한 SNR을 보였고 CNR은 FIR과 3D GRE 모두 SE보다 우수하였으며 FIR보다 3D GRE가 더 우수하였다. 회백질-백질의 구분과 수초화 유무 역시 스핀에코보다 FIR과 3D GRE에서 더 잘 보였다. 그러나 3D GRE는 움직임에 의한 인공음영이 많았고 FIR에서 혈류에 의한 혈관의 고신호강도가 자주 발견되었다. 결론: 3T 장비에서 신생아 뇌영상을 얻을 때 FIR과 3D GRE 기법은 SE보다 좋은 T1 강조영상을 제공할 것으로 기대된다.

• 한국CDE학회논문집
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• 제3권2호
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• pp.127-134
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• 1998

This paper presents d new algorithm to compute the offlet curve of a given planar parametric curve. We reduce the problem of computing an offset curve to that of intersecting a surface to a paraboloid. Given an input curve C(t)=(x(t), y(t))∈R², the corresponding surface D/sub c(t)/ is constructed symbolically as the envelope surface of a one-parameter family of tangent planes of the paraboloid Q:z=x²+y²along a lifted curve C(t)=(x(t), y(t), x(t)²+y(t)²∈Q. Given an offset distance d∈R, the offset curve C/sub d/(t) is obtained by the projection of the intersection curve of D/sub c(t)/ and a paraboloid Q:z=x²+y²-d² into the xy-plane.

• 대한수학회지
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• 제58권3호
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• pp.643-702
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• 2021

Fix ℤ/2 is the prime field of two elements and write 𝒜₂ for the mod 2 Steenrod algebra. Denote by GL_d := GL(d, ℤ/2) the general linear group of rank d over ℤ/2 and by ${\mathfrak{P}}_d$ the polynomial algebra ℤ/2[x₁, x₂, …, x_d] as a connected unstable 𝒜₂-module on d generators of degree one. We study the Peterson "hit problem" of finding the minimal set of 𝒜₂-generators for ${\mathfrak{P}}_d$. Equivalently, we need to determine a basis for the ℤ/2-vector space $$Q{\mathfrak{P}}_d:={\mathbb{Z}}/2{\otimes}_{\mathcal{A}_2}\;{\mathfrak{P}}_d{\sim_=}{\mathfrak{P}}_d/{\mathcal{A}}^+_2{\mathfrak{P}}_d$$ in each degree n ≥ 1. Note that this space is a representation of GL_d over ℤ/2. The problem for d = 5 is not yet completely solved, and unknown in general. In this work, we give an explicit solution to the hit problem of five variables in the generic degree n = r(2^t - 1) + 2^ts with r = d = 5, s = 8 and t an arbitrary non-negative integer. An application of this study to the cases t = 0 and t = 1 shows that the Singer algebraic transfer of rank 5 is an isomorphism in the bidegrees (5, 5 + (13.2⁰ - 5)) and (5, 5 + (13.2¹ - 5)). Moreover, the result when t ≥ 2 was also discussed. Here, the Singer transfer of rank d is a ℤ/2-algebra homomorphism from GL_d-coinvariants of certain subspaces of $Q{\mathfrak{P}}_d$ to the cohomology groups of the Steenrod algebra, $Ext^{d,d+*}_{\mathcal{A}_2}$ (ℤ/2, ℤ/2). It is one of the useful tools for studying these mysterious Ext groups.