• The Transactions of The Korean Institute of Electrical Engineers
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• v.65 no.5
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• pp.825-830
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• 2016

The purpose of this study optimizes the conditions of PLA printing material for 3D printer. Deltabot type 3D printer is used. The ranges of printing temperature, printing speed, and infill density are $195{\sim}215^{\circ}C$, 10~70mm/sec, and 10~100% respectively. From the results of printing temperature, printing quality is almost same every printing temperature. From the results of printing speed and infill density, printing quality is excellent under 40mm/sec, and over 50% respectively. Surface roughness is $2.28{\mu}mRa$ at $205^{\circ}C$, 10mm/sec, 100%, and is $5.93{\mu}mRa$ at $205^{\circ}C$, 70mm/sec. Surface roughness is directly proportional to the printing speed, and is inversely proportional to the infill density. Objects fabricated PLA printing material adhere bed at room temperature.

• IMMUNE NETWORK
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• v.11 no.5
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• pp.281-287
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• 2011

Background: Biodegradable polymers have increasingly been recognized for various biological applications in recent years. Here we examined the immunostimulatory activities of the novel poly(aspartic acid) conjugated with L-lysine (PLA). Methods: PLA was synthesized by conjugating L-lysine to aspartic acid polymer. PLA-nanoliposomes (PLA-NLs) were prepared from PLA using a microfluidizer. The immunostimulatory activities of PLA-NLs were examined in mouse bone marrow-derived dendritic cells (BM-DCs). Results: PLA-NLs increased the number of BM-DCs when added to cultures of GM-CSF-induced DC generation on day 4 after the initiation of cultures. Examination of the phenotypic properties showed that BM-DCs generated in the presence of PLA-NLs are more mature in terms of the expression of MHC class II molecules and major co-stimulatory molecules than BM-DCs generated in the absence of PLA-NLs. In addition, the BM-DCs exhibited enhanced capability to produce cytokines, such as IL-6, IL-12, TNF-${\alpha}$ and IL-$1{\beta}$. Allogeneic mixed lymphocyte reactions also confirmed that the BMDCs were more stimulatory on allogeneic T cells. PLA- NL also induced further growth of immature BM-DCs that were harvested on day 8. Conclusion: These results show that PLA-NLs induce the generation and functional activities of BM-DCs, and suggest that PLA-NLs could be immunostimulating agents that target DCs.

• Journal of the Korean Wood Science and Technology
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• v.52 no.3
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• pp.205-220
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• 2024

Various polylactic acid (PLA) blends were reinforced with untreated or silane-treated micro-sized cellulose fiber (MCF), successfully prepared as 3D printing filaments and then printed using a fused filament fabrication (FFF) 3D printer. In this study, we focused on developing 3D-printed MCF/PLA composites through silane treatment of MCF and investigating the effect of silane treatment on the various properties of FFF 3D-printed composites. Fourier transform infrared spectra confirmed the increase in hydrophobic properties of silane-treated MCF by showing the new absorption peaks at 1,100 cm^-1, 1,030 cm^-1, and 815 cm^-1 representing C-NH₂, Si-O-Si, and Si-CH₂ bonds, respectively. In scanning electron microscope images of silane-treated MCF filled PLA composites, the improved interfacial adhesion between MCF and PLA matrix was observed. The mechanical properties of the 3D-printed MCF/PLA composites with silane-treated MCF were improved compared to those of the 3D-printed MCF/PLA composites with untreated MCF. In particular, the highest tensile and flexural modulus values were observed for S-MCF10 (5,784.77 MPa) and S-MCF5 (2,441.67 MPa), respectively. The thermal stability of silane-treated MCF was enhanced by delaying the initial thermal decomposition temperature compared to untreated MCF. The thermal decomposition temperature difference at T₉₅ was around 26℃. This study suggests that the effect of silane treatment on the 3D-printed MCF/PLA composites is effective and promising.

• Macromolecular Research
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• v.14 no.5
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• pp.510-516
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• 2006

Lactide was produced from oligomeric PLA by back-biting reaction of the OH end groups. For optimization of the reaction conditions, the effects of temperature, pressure, PLA molecular weight, and catalyst type on the lactide synthesis were examined. The fraction of D,L-lactide decreased with increasing temperature. Among the various Sn-based catalysts, the D,L-lactide fraction was maximized when SnO was used. A higher yield with lower racemization was observed at lower pressure. The conversion of PLA was maximized at an oligomeric PLA molecular weight of ca. 1380. The yield of lactide increased but the fraction of D,L-lactide decreased with increasing molecular weight. The highest conversion with the lowest racemization degree was obtained at a catalyst concentration of 0.1 wt%. The lactide was more sensitive to racemization because of the entropic effect.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.14 no.3
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• pp.1065-1085
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• 2020

With rapid growth of content demands, device-to-device (D2D) content sharing is exploited to effectively improve the service quality of users. Considering the limited storage space and various content demands of users, caching schemes are significant. However, most of them ignore the influence of the asynchronous content reuse and the selfishness of users. In this work, the user preferences are defined by exploiting the user-oriented content popularity and the current caching situation, and further, we propose the social-aware rate, which comprehensively reflects the achievable contents download rate affected by the social ties, the caching indicators, and the user preferences. Guided by this, we model the collaborative caching problem by making a trade-off between the redundancy of caching contents and the cache hit ratio, with the goal of maximizing the sum of social-aware rate over the constraint of limited storage space. Due to its intractability, it is computationally reduced to the maximization of a monotone submodular function, subject to a matroid constraint. Subsequently, two social-aware collaborative caching algorithms are designed by leveraging the standard and continuous greedy algorithms respectively, which are proved to achieve different approximation ratios in unequal polynomial-time. We present the simulation results to illustrate the performance of our schemes.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.10 no.11
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• pp.5209-5228
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• 2016

Device-to-device (D2D) communication underlaying cellular networks can bring significate benefits for improving the performance of mobile services. However, it hinges on elaborate resource sharing scheme to coordinate interference between cellular users and D2D pairs. We formulate a joint mode selection, link allocation and power control optimization problem for D2D communication sharing uplink resources in a multi-user cellular network and consider the efficiency and the fairness simultaneously. Due to the non-convex difficulty, we propose a three-step scheme: firstly, we conduct mode selection for D2D pairs based on a minimum distance metric after an admission control and obtain some cellular candidates for them. And then, a cellular candidate will be paired to each D2D pair based on fairness. Finally, we use Lagrangian Algorithm to formulate a joint power control strategy for D2D pairs and their reused cellular users and a closed-form of solution is derived. Simulation results demonstrate that our proposed algorithms converge in a short time. Moreover, both the sum rate of D2D pairs and the energy efficiency of cellular users are improved.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.19 no.3
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• pp.1-7
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• 2020

Fused filament fabrication (FFF) is a process extruding and stacking materials. PLA materials are one of the most frequently used materials for FFF method of 3D printing. Polylactic acid (PLA)-based materials are among the most widely used materials for FFF-based three-dimensional (3D) printing. PLA is an eco-friendly material made using starch extracted from corn, as opposed to plastic made using conventional petroleum resin; PLA-based materials are used in various fields, such as packaging, aerospace, and medicines. However, it is important to analyze the mechanical properties of theses materials, such as elastic strength, before using them as structural materials. In this study, the reliability of PLA-based materials is assessed through an analysis of the changes in the linear elasticity of these materials under thermal degradation by applying a hyperelastic analytical model.

• Journal of the Korean Society of Radiology
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• v.13 no.7
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• pp.909-916
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• 2019

Radiation therapy of oral and head and neck cancers often involves skin in the therapeutic range, and the use of bolus is frequently used. Dose irregularities provide dose uncertainty in patient application. In this study, the physical properties of patients with gel bolus, poly lactic acid (PLA), and silicon using 3D printing were fabricated. Dose uncertainties arising from the actual radiation dose delivery were measured. As a result, PLA bolus was stable in the Common irregularities. Silicon bolus may be useful for patients with severe irregularities or frequent changes in patient's body shape.

• Journal of Convergence for Information Technology
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• v.10 no.11
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• pp.218-223
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• 2020

This study was conducted to observe the difference in muscle activity by IASTM between a tool made of PLA made with a 3D printer and a tool made of ready-made stainless steel. This study was attended by 10 adults in their twenties, and all subjects participated in both the PLA group and the Stainless group, received IASTM. %MVIC was measured by measuring muscle activity after intervention, and this was verified through comparison between groups through the Mann-Whitney U test. The results of this study showed that there was no significant difference between the two groups in the %MVIC value of the biceps brachii after intervention. Therefore, in the application of IASTM, there was no difference in muscle activity depending on the material of the tool, which seems to be that the IASTM tool made of PLA made with a 3D printer produced similar results in the ability to control neuromuscular muscles and the ready-made product made of stainless steel. Therefore, in a future study, the effectiveness of the tool will be verified for the various patient group.

• Journal of Pharmaceutical Investigation
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• v.26 no.1
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• pp.13-22
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• 1996

Poly(D,L-lactic acid) (PLA) microspheres containing alprazolam(APZ) were prepared by a solvent-emulsion evaporation method and their release patterns were investigated in vitro. Various batches of microspheres with different size and drug content were obtained by changing the ratio of APZ to PLA, PLA concentration in the dispersed phase and stirring rate. Rod-like APZ crystals on microsphere surface, which were released rapidly and could act as a loading dose, were observed with increasing drug content. The release rate was increased with increase in drug contents and decrease in the molecular weight of PLA. The release rate of APZ for long-acting injectable delivery system in vitro, which would aid in predicting in vitro release profile, could be controlled by properly optimizing various factors affecting characteristics of microspheres.