• Journal of the Korea Institute of Military Science and Technology
• /
• v.17 no.4
• /
• pp.404-412
• /
• 2014

We proposed a design method for squib current supply & interlock circuits in guided-missile fire control systems. In order to design squib current supply circuits, various missile squib loads including line resistance and squib devices have to be considered in advance minimizing probability of redesign of circuits and reducing the development cost by implementing the most proper squib current supply circuit. Also, we presented a hardware interlock logic instead of the commonly used software safety logic to improve the safety of guided-missile fire control systems. The proposed squib interlock circuit enhances safety requirements of guided-missile fire control systems. We confirmed that simulation and measurement results of the proposed design method are the same as theoretical analysis results.

• Journal of Information Display
• /
• v.13 no.2
• /
• pp.73-82
• /
• 2012

In this paper, a light-emitting diode (LED) backlight driver integrated circuit (IC) for medium-sized liquid crystal displays (LCDs) is proposed. In the proposed IC, a linear current regulator with matched internal resistors and an adaptive phase-shifted pulse-width modulation (PWM) dimming controller are also proposed to improve LED current uniformity and reliability. The double feedback loop control boost converter is used to achieve high power efficiency, fast transient characteristic, and high dimming frequency and resolution. The proposed IC was fabricated using the 0.35 ${\mu}m$ bipolar-CMOS-DMOS (BCD) process. The LED current uniformity and LED fault immunity of the proposed IC were verified through experiments. The measured power efficiency was 90%; the measured LED current uniformity, 97%; and the measured rising and falling times of the LED current, 86 and 7 ns, respectively. Due to the fast rising and falling characteristics, the proposed IC operates up to 39 kHz PWM dimming frequency, with an 8-bit dimming resolution. It was verified that the phase difference between the PWM dimming signals is changed adaptively when LED fault occurs. The experiment results showed that the proposed IC meets the requirements for the LED backlight driver IC for medium-sized LCDs.

• Journal of IKEEE
• /
• v.14 no.2
• /
• pp.1-8
• /
• 2010

In this paper, Green Mode Power IC is designed to reduce the standby power. The proposed and designed IC works for the Switch Mode Power Supply(SMPS) and has the function of PWM. To reduce the unnecessary electric power, burst mode and skip mode section are introduced and controlled by external power MOSFET to diminish the standby power. The proposed IC is designed and simulated by KEC 30V-High Voltage 0.5um CMOS Process. The structure of proposed IC is composed of voltage regulator circuit, voltage reference circuit, UVLO(Under Voltage Lock out) circuit, Ibias circuit, green circuit, PWM circuit, OSC circuit, protection circuit, control circuit, and level & driver circuit. Measuring the current consumption of each block from the simulation results, 1.2942 mA of the summing consumption current from each block is calculated and ot proved that it is within the our design target of 1.3 mA. The current consumption of the proposed IC in this paper is less than a half of conventional ICs, and power consumption is reduced to the extent of 1W in standby mode. From the above results, we know that efficiency of proposed IC is superior to the previous IC.

• 전자공학회논문지 IE
• /
• v.47 no.2
• /
• pp.13-20
• /
• 2010

This paper describes a current mode PWM DC-DC converter IC for battery charger and supply power converter for portable electronic devices. The maximum supply voltage of IC is 40[V] and 2.8[V]~330[V] DC input power is converted to higher or programmed DC voltage according to external resistor ratio or wire winding ratio of transformer. The maximum supply output current is 3[A] over and voltage error of output node is within 3[%]. The whole circuit needed current mode PWM DC-DC converter circuit is designed. The package dimensions and number of external parts are minimized in order to get a smaller hardware size. The power consumption is smaller then 1[mW] at stand by period with supply voltage of 3.6[V] and maximum energy conversion efficiency is about 86[%]. This device has been designed in a 0.6[um] double poly, double metal 40[V] CMOS process and whole chip size is 2100*2000 [um2].

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
• /
• v.21 no.5
• /
• pp.82-89
• /
• 2007

AVR(Automatic Voltage Regulator) of exciter control system in AC generator controls voltage and current according to load and terminal voltage variations in order to remain at the bus voltage. The output characteristics of main generator is dependent on the control performance of AVR. This paper presents the PWM type exciter system with transient response compensator for robust control of load variations. Additional transient response compensator generates compensation signal for load variation. So the proposed excitation control system has fast dynamic response in transient period and can control terminal voltage constantly. The proposed method is verified by the computer simulation and experimental results in prototype generation system.

• Journal of the Korea Institute of Information and Communication Engineering
• /
• v.16 no.9
• /
• pp.2003-2008
• /
• 2012

A drive system is necessary to operate LED by an LED illumination system. Because Switched Mode Power Supply (SMPS) is higher in efficiency in the large capacity than Linear Regulator, it is used mainly and controls this in an analog form or digital method. A MCU and a DSP of the digital control central processing unit were higher in a unit price than existing analog control chip, so that an approach was not easy for application of SMPS. But it can take the earnings by it lets you integrate various digital control features like an LED illumination system in one MCU, and realizing a whole system. In this paper, we suggest the algorithm that can improve LED driving current in applying such a digital control method using low-priced type MCU.

• Journal of IKEEE
• /
• v.20 no.3
• /
• pp.260-264
• /
• 2016

The MAX77846, which is compatible with MAX77826, is a sub-power management IC (PMIC) for the latest Wearable Watch and 3G/4G smart phones. The MAX77846 contains N-MOSFET (N channel Metal-Oxide Semiconductor Field-Effect Transistor), a high-efficiency regulator, and comparator, etc to power up peripherals. The MAX77846 also provides power on/off control logic for complete flexibility and an $I^2C$ (Inter Integrated Circuit) serial interface to program individual regulator output voltages. In this paper, the simplified power macro-model based on MAX77846 is designed to verify the performance of the battery voltage in terms of current and time, and simulated by using of the LTspice. In addition, it is verified how much time can the charged battery capacity for Samsung Galaxy Gear 2 be used to operate a specified function after measuring the currents flowing to carry out the main functions in real time, which will be applicable to design parameters for the advanced power module

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
• /
• 2014.10a
• /
• pp.585-588
• /
• 2014

This paper presents a self-powered sensor node circuit using photovoltaic and vibration energy harvesting. The harvested energy from a solar cell and a vibration device(PZT) is stored in a storage capacitor. The stored energy is managed by a PMU(Power Management Unit). In order to supply a stable voltage to the sensor node, an LDO(Low Drop Out Regulator) is used. The LDO drives a temperature sensor and a SAR ADC(Successive Approximate Register Analog-to-Digital Converter), and 10-bit digital output data corresponding to current temperature is obtained. The proposed circuit is designed in a 0.35um CMOS process, and the designed chip size including PADs is $1.1mm{\times}0.95mm$.

• IMMUNE NETWORK
• /
• v.22 no.3
• /
• pp.21.1-21.21
• /
• 2022

As far the current severe coronavirus disease 2019 (COVID-19), respiratory disease is still the biggest threat to human health. In addition, infectious respiratory diseases are particularly prominent. In addition to killing and clearing the infection pathogen directly, regulating the immune responses against the pathogens is also an important therapeutic modality. Sirtuins belong to NAD+-dependent class III histone deacetylases. Among 7 types of sirtuins, silent information regulator type-1 (SIRT1) played a multitasking role in modulating a wide range of physiological processes, including oxidative stress, inflammation, cell apoptosis, autophagy, antibacterial and antiviral functions. It showed a critical effect in regulating immune responses by deacetylation modification, especially through high-mobility group box 1 (HMGB1), a core molecule regulating the immune system. SIRT1 was associated with many respiratory diseases, including COVID-19 infection, bacterial pneumonia, tuberculosis, and so on. Here, we reviewed the latest research progress regarding the effects of SIRT1 on immune system in respiratory diseases. First, the structure and catalytic characteristics of SIRT1 were introduced. Next, the roles of SIRT1, and the mechanisms underlying the immune regulatory effect through HMGB1, as well as the specific activators/inhibitors of SIRT1, were elaborated. Finally, the multitasking roles of SIRT1 in several respiratory diseases were discussed separately. Taken together, this review implied that SIRT1 could serve as a promising specific therapeutic target for the treatment of respiratory diseases.

• Oncology Letters
• /
• v.17 no.3
• /
• pp.3589-3598
• /
• 2019

Colorectal cancer (CRC) is a complex disease involving numerous genetic abnormalities. One of the major characteristics of CRC is enhanced Wnt signaling caused by loss-of-function mutations in the adenomatous polyposis coli (APC) gene. Previously, it has been demonstrated that the majority of malignant phenotypes following APC deletion in adult murine small intestines could be rescued when Myc, a downstream target of the Wnt pathway, was deleted. This indicated that Myc is a critical regulator of CRC development following APC loss. Previous studies reported that cyclic adenosine 3',5'-monophosphate (cAMP) can influence the AKT/mammalian target of rapamycin (mTOR) survival pathway in cancer and Myc is a critical downstream molecule of AKT/mTOR signaling. Phosphodiesterase 4D (PDE4D), a member of the cAMP-specific PDE4 family, has been associated with drug resistance in CRC. However, the association between PDE4D and Myc remains unclear. To investigate the potential role of PDE4D in Myc regulation in CRC, the present study evaluated the expression levels of PDE4 subtypes in DLD-1 CRC cells. Additionally, the effects of PDE4 inhibitors on Myc expression and oncogenic properties were analyzed by western blot analysis, reverse transcription-quantitative polymerase chain reaction, colony formation and soft agar assays. It was demonstrated that cAMP/PDE4D signals serve a critical role in regulating Myc expression in DLD-1 CRC cells. Furthermore, PDE4D was identified to be a main hydrolyzer of cAMP and suppression of PDE4D using selective inhibitors of PDE4 increased intracellular cAMP levels, which resulted in a marked decrease in the oncogenic properties of DLD-1 cells, including colony formation, cell proliferation and anchorage-independent growth. Notably, the current data imply that cAMP represses Myc expression via the downregulation of AKT/mTOR signaling, which was abolished by high PDE4D activities in DLD-1 cells. Additionally, a natural polyphenol resveratrol in combination with forskolin elevated the concentration of cAMP and enhanced the expression of Myc and the malignant phenotype of DLD-1 cells, reproducing the effect of known chemical inhibitors of PDE4. In conclusion, the present study identified that cAMP/PDE4D signaling is a critical regulator of Myc expression in DLD-1 and possibly other CRC cells.