• Structural Engineering and Mechanics
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• 제14권5호
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• pp.565-574
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• 2002

This paper presents a method for predicting premature separation of carbon fiber reinforced plastic (CFRP) plates from strengthened steel beams. The fracture criterion based on material-induced singularity is formulated in terms of a singular intensity factor. Static test on double strap joints was selected to provide the critical stress intensity factor in the criterion because good degree of accuracy and consistency of experimental data can be expected compared with the unsymmetrically loaded single lap joints. The debond/separation loads of steel beams with different CFRP lengths were measured and compared with those predicted from the criterion. Good agreement between the test results and the prediction was found.

• 산업경영시스템학회지
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• 제34권1호
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• pp.80-89
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• 2011

In service science, it is critical to measure service satisfaction for innovating service processes, which is challenging for service sectors oriented to the usage of IT systems. For that purpose, in this study, a model based on the technology acceptance model and satisfaction measurement model is proposed. The model is empirically tested using data sets from a public service sector (G2B) and a private service sector (internet banking). The purpose of this study is to identify factors which affect the service satisfaction. The result shows that a public service sector is less sensitive to the IT systems on which its services are operated, and that the attitude factor strongly affects the service satisfaction in both sectors.

• BMB Reports
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• 제47권7호
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• pp.405-410
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• 2014

ZBTB3 belongs to the Zinc finger and BTB/POZ domain containing transcription factor family; however, its biological role has rarely been studied. We demonstrate for the first time, to our knowledge, that ZBTB3 is an essential factor for cancer cell growth via the regulation of the ROS detoxification pathway. Suppression of ZBTB3 using two different short hairpin RNAs in human melanoma, lung carcinoma, and breast carcinoma results in diminished cell growth. In addition, we found that suppression of ZBTB3 activates a caspase cascade, including caspase-9, -3, and PARP leading to cellular apoptosis, resulting from failed ROS detoxification. We identified that ZBTB3 plays an important role in the gene expression of ROS detoxification enzymes. Our results reveal that ZBTB3 may play a critical role in cancer cell growth via the ROS detoxification system. Therefore, therapeutic strategies that target ZBTB3 could be used in selective cancer treatments.

• 한국안전학회지
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• 제29권1호
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• pp.59-63
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• 2014

Smoke is one of the most critical factor when escaping from the fire since it reduces visibility and interrupts finding emergency exit lights. Therefore, it is recommended that an evacuation simulation program should incorporate the smoke factor. In addition, it is suggested that the program should include not only the unilateral damage by the smoke but also the detour evacuation by risk communication. In this study, MAS (Multi Agent System)-based simulation program which incorporates the reduced walking speed by smoke and adopts the dispersion evacuation logic during escaping from the fire. To make comparison, a commercial evacuation program, Pathfinder was used. It was found that the simulation results of MAS (Multi Agent System)-based program is better than Pathfinder in terms of safe evacuation. It means that evacuation simulation need a additional evaluation categories that include not only quick evacuation time but also safe evacuee number.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2006년도 추계학술대회논문집
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• pp.492-497
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• 2006

This study gives the results of the measurements and analysises of the reverberation times in a small room such as apartment houses. We measured the RT by changing measurement conditions, which were sound sources. sound source's positions, receiving point & height, sampling time and so on. The critical factor affecting reverberation time was sound source in unoccupied houses and the reverberation time differences between result of RT using impulsive and interrupted sound source was 0.3sec at 500Hz frequency. And the difference of RT due to sound sources affected the sound insulation such as apparent sound reduction index and sound level difference about 1dB at each frequency in unoccupied houses.

• Tuberculosis and Respiratory Diseases
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• 제83권1호
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• pp.81-88
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• 2020

Background: Use of appropriate antibiotics for the treatment of pneumonia is integral in patients admitted to intensive care units (ICUs). Although it is recommended that empirical treatment regimens should be based on the local distribution of pathogens in patients with suspected hospital-acquired pneumonia, few studies observe patients admitted to ICUs with nursing home-acquired pneumonia (NHAP). We found factors associated with the use of inappropriate antibiotics in patients with pneumonia admitted to the ICU via the emergency room (ER). Methods: We performed a retrospective cohort study of 83 pneumonia patients with confirmed causative bacteria admitted to ICUs via ER March 2015-May 2017. We compared clinical parameters, between patients who received appropriate or inappropriate antibiotics using the Mann-Whitney U, Pearson's chi-square, and Fisher's exact tests. We investigated independent factors associated with inappropriate antibiotic use in patients using multivariate logistic regression. Results: Among 83 patients, 30 patients (36.1%) received inappropriate antibiotics. NHAP patients were more frequently treated with inappropriate antibiotics than with appropriate antibiotics (47.2% vs. 96.7%, p<0.001). Methicillin-resistant Staphylococcus aureus was more frequently isolated from individuals in the inappropriate antibiotics-treated group than in the appropriate antibiotics-treated group (7.5% vs. 70.0%, p<0.001). In multivariate analysis, NHAP was independently associated with the use of inappropriate antibiotics in patients with pneumonia admitted to the ICU via ER. Conclusion: NHAP is a risk factor associated with the use of inappropriate antibiotics in patients with pneumonia admitted to the ICU via the ER.

• 중환자간호학회지
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• 제12권2호
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• pp.1-12
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• 2019

Purpose : The purpose of this study was to validate the Korean version of Partners In Health scale (PIH-K) which is used to measure the self-management of patients with chronic illnesses in Korea. Methods : Translation of the 12-item PIH-K was conducted according to the World Health Organization guidelines. Data from 306 participants who took medicines over 3 months by doctor's prescription were collected from October to November 2017. Validity such as content validity, construct validity, and concurrent validity were conducted using content validity index (CVI), exploratory and confirmatory factor analyses (CFA). To evaluate concurrent validity, the correlation coefficients between the PIH-K and concurrent scales (Self-As-Carer Inventory) were calculated. The reliability of the PIH-K was examined using the internal consistency and test-retest reliability tests. Results : The CVI of the PIH-K was 0.91. According to the CFA, factor loadings for four factors ranged from .64 to .97, which explained 67.5% of the total variance. The PIH-K was significantly correlated with concurrent variables such as those on the Self-As-Carer Inventory. The Cronbach's ${\alpha}$ was .86 and the intraclass correlation coefficient for the two-week test-retest reliability was .88. Conclusion : Findings show that the PIH-K is reliable and valid in measuring self-management of patients with chronic illnesses.

• 한국추진공학회지
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• 제5권4호
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• pp.31-39
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• 2001

복합재료로 제작이 되는 수송기계용 추진축은 진동, 소음, 중량 등을 감소시킬 수 있는 장점을 가진다. 본 연구에서는 유한요소법을 이용하여 카본/에폭시 복합재료로 구성된 추진축을 설계하였으며 필라멘트 와인딩 방법을 사용하여 시험용 시편을 제작하였다. 유한요소법을 이용한 추진축의 설계 방법의 정확성을 확인하고자 FFT 해석기와 충격해머를 이용한 고유진동수 측정시험과 임계회전속도 측정 실험 장비를 이용한 임계회전속도 측정시험을 수행하였다. 해석결과와 시험결과를 비교하였을 때 오차율은 3.4%이하로 해석결과의 신뢰성을 확인하였다. 이러한 FEM 설계방법을 이용하여 추진 축의 진동 및 강도특성에 영향을 미치는 요인들에 대한 연구를 수행하였다 여러 요인들 중 중량의 증가 없이 고유진동수 변화에 가장 큰 영향을 미치는 것은 와인딩 각도임을 확인하였다.

• 대한기계학회논문집A
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• 제34권9호
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• pp.1185-1191
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• 2010

장기운영된 항공기에는 비행시간의 누적에 따라 다양한 피로균열이 발생하며 이는 운영상 안전성 및 가동률을 저하시키는 요인이 된다. 이의 해결을 위하여 피로임계위치(Fatigue critical location, FCL)에 대한 균열 진전 해석은 매우 중요하다. 그러나 이러한 장기 운영된 항공기의 경우, 균열 진전 해석에 필수적인 FCL에서의 응력 스펙트럼 획득은 거의 불가능한 실정이다. 본 연구에서는 장기운영된 항공기 주익 구조물의 FCL에서의 균열 진전 해석을 수행하기 위하여, 먼저 주익 구조물에 대한 2차원 하드카피 형태의 도면으로부터 구축된 3차원 CAD 모델에 대한 유한요소해석을 수행하였다. 또한 이러한 유한요소해석 결과 및 제한된 하중배수 자료를 기반으로 FCL에서의 전달함수와 응력 스펙트럼을 산출하였다. 상기 자료를 바탕으로 상용 균열 진전 해석 코드인 NASGRO를 이용하여 FCL에서의 균열진전해석을 수행하였다.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 1995년도 봄 학술발표회 논문집
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• pp.237-244
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• 1995

Fracture properties for LEFM, S-FPZ and NS-FPZ models were determined using by finite element method and energy balance from the experimental results of three-point bend tests. For the LEFM model the stress intensity factor needed to increase continuously with crack extension, and for the S-FPZ model the fracture process zone characteristics need to change continuously if the critical stress intensity factor was to remain constant. The LEFM model showed the largest resistance and the slowest crack extension, while the NS-FPZ model showed the smallest resistance and the fastest crack extension. The responses for the S-FPZ model were intermediate between those for the LEFM and NS-FPZ models and the total fracture energy densities for the S-FPZ and NS-FPZ models and the total fracture energy densities for the S-FPZ and NS-FPZ models were equal.