• Title/Summary/Keyword: Core effect

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Construction of Environmental Friendly Special-Purpose Ship for the Removal of Blue-green Algae (친환경적 녹조 제거용 특수선박 건조)

  • Shin, Jae-Ki;Yi, Hye-Suk;Jeong, Sun-A;Hwang, Soon-Jin
    • Korean Journal of Ecology and Environment
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    • v.42 no.3
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    • pp.404-406
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    • 2009
  • This study note wished to introduce special-purpose ship for algae removal that is developed by core technology of our country. The ship is consisted of main frame and adjuvant that can attach and detach as cross (+) shape of a character. The characteristics of ship are super light weight and low draft. That is consisted of four devices as suction, collection, filtration and recovering units. Among these, filtration used screen filter (mesh size 30 ${\mu}m$). Also, can separate and remove water and algae by compression air participle notion. Percentage of moisture content of concentrated algal particle was 85%. Water parted with algae finally is exhausted to water area. Removal efficiency that compare by chlorophyll-$\alpha$ concentration was about 57% (inflow: 83.2 ${\mu}g\;L^{-1}$, outflow: 35.8 $[\mu}g\;L^{-1}$) without physical and chemical pretreatment. Forward, need to achieve effect test in various conditions (algal biomass, flow etc.) for efficiency and technological elevation of exclusion device. We wished to contribute in presuppression system construction of massive algal development that manage blue-green algae occurrence area effectively, and prevents spread as lower part of reservoir.

Consent for using human biological material in research: based on the revised Bioethics and Safety Act (인체유래물연구에 대한 동의 소고(小考) - 개정 생명윤리법 제42조의2를 계기로 -)

  • Lee, Dongjin;Lee, Sun Goo
    • The Korean Society of Law and Medicine
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    • v.20 no.2
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    • pp.111-140
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    • 2019
  • The Bioethics and Safety Act provides a set of rules to regulate biobanks and research activities using human biological material, but the law seems to be defective in several folds. The law requires that, prior to collection or use of human biological materials, researchers should obtain the informed consent of the donors, but the law does not obligate biobanks to do so. Even in cases where the law requires informed consent, the ordinance of the Ministry of Health and Welfare allows open (or blanket) consent. In addition, a new article in the Act, Article 42-2 which will take effect from October 24, 2019, allows medical institutions to provide biobanks with remaining biospecimens collected in the course of diagnosis and treatment, unless the donors express their intent to opt-out, without obtaining specific consent from them. Given the need to protect the autonomy of donors and the unique characteristics of biobanks and research activities that use human biological materials, this paper concludes that such open consent-based law may not be suitable to protect the autonomy of the donors and that the broad consent requirement may be a desirable policy option. The paper acknowledges that the international community has long questioned whether broad consent (as well as open consent) is an effective choice to regulate the use of human biological materials. The paper stresses that the baseline requirement in designing the law is that the secondary use of human biological materials should be based on informed consent of the donors; the core value of the law should be a governance structure that promotes transparency and protects donor participation.

Spatial and Vertical Distribution of Polycyclic Aromatic Hydrocarbons in Sediment of the Shipyard Area in Gohyeon Bay (고현만 조선소 주변해역 퇴적물내 다환방향족탄화수소의 시공간적 분포특성)

  • Park, Pan-Soo;Kim, Nam-Sook;Yim, Un-Hyuk;Shim, Won-Joon;Kim, Gi-Beum
    • Journal of the Korean Society for Marine Environment & Energy
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    • v.12 no.2
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    • pp.68-74
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    • 2009
  • Polycyclic aromatic hydrocarbons (PAHs), one of ubiquitous organic pollutants in marine environments, are major toxic components of petroleum and are produced during the incomplete combustion of organic materials. As shipyards are located inside of natural or artificial semi-enclosed bay, even a relatively weak environmental disturbance by ship-building activity can cause severe damage to marine ecosystem in the bay. Many studies of pollution in shipyard area have been focused on the antifouling agent, like tributyltin. This study aimed to investigate the effect of ship-building activity on PAH contamination. Total PAHs concentration was higher nearby and inside shipyard area than outside, implying that shipyard could be one of major source area of PAH contamination to pose harmful effects to surrounding environments. Through PAH profile and source recognition index, the source of PAHs inputs in this area was estimated to originate from both petrogenic and pyrogenic origin. PAH levels showed a significant correlation with total butyltins, indicating that ship-building activity influenced PAH concentration and distribution. Vertical distribution of PAHs historically confirmed the correlation between shipbuilding activity and PAHs contamination.

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Emerging Media Conglomerates and Producers' Exodus: The Dynamics of Creativity Relocations in the South Korean Broadcasting Production Sector after the Introduction of New General Programming Channels (신규 복합 미디어 기업의 부상과 제작자 엑서더스: 종합편성채널 승인 이후 방송제작 부문의 창의성 재배치 동학)

  • Jung, June-Hee
    • Korean journal of communication and information
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    • v.66
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    • pp.28-58
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    • 2014
  • South Korean broadcasting industry has been under a significant level of structural change since the permission of new general programming channels in the end of 2010. One of the most characteristic features of the change may be the exodus of core manpower from the in-house productions of major terrestrial broadcasters which have been maintaining their dominant power over broadcasting content market based on their systems of tight vertical integration. This paper sheds light on the presence of a purposeful 'mechanism design' that aims to the expansion of market logics in South Korean broadcasting sector by promoting commercial media conglomerates, and analyses how this external design has been actualized while being interlocked with various internal factors of the broadcasting industry. This paper shows that on the backdrop of the mechanism design, some of new media conglomerates has successfully provided various incentives in contrast with those disincentive of terrestrial broadcasters, which in turn, has facilitated the exodus of elite producers. This paper, however, raises a set of questions about whether this relocation process of creativity led by commercial media conglomerates would, in the long term, guarantee more opportunities and potentials for the producers, as promised. As part of conclusion, inherent problems of present mechanism design are highlighted.

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Local Drug Delivery System Using Biodegradable Polymers

  • Khang, Gil-Son;Rhee, John M.;Jeong, Je-Kyo;Lee, Jeong-Sik;Kim, Moon-Suk;Cho, Sun-Hang;Lee, Hai-Bang
    • Macromolecular Research
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    • v.11 no.4
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    • pp.207-223
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    • 2003
  • For last five years, we are developing the novel local drug delivery devices using biodegradable polymers, especially polylactide (PLA) and poly(D,L-lactide-co-glycolide) (PLGA) due to its relatively good biocompatibility, easily controlled biodegradability, good processability and only FDA approved synthetic degradable polymers. The relationship between various kinds of drug [water soluble small molecule drugs: gentamicin sulfate (GS), fentanyl citrate (FC), BCNU, azidothymidine (AZT), pamidronate (ADP), $1,25(OH)_2$ vitamin $D_3$, water insoluble small molecule drugs: fentanyl, ipriflavone (IP) and nifedipine, and water soluble large peptide molecule drug: nerve growth factor (NGF), and Japanese encephalitis virus (JEV)], different types of geometrical devices [microspheres (MSs), microcapsule, nanoparticle, wafers, pellet, beads, multiple-layered beads, implants, fiber, scaffolds, and films], and pharmacological activity are proposed and discussed for the application of pharmaceutics and tissue engineering. Also, local drug delivery devices proposed in this work are introduced in view of preparation method, drug release behavior, biocompatibility, pharmacological effect, and animal studies. In conclusion, we can control the drug release profiles varying with the preparation, formulation and geometrical parameters. Moreover, any types of drug were successfully applicable to achieve linear sustained release from short period ($1{\sim}3$ days) to long period (over 2 months). It is very important to design a suitable formulation for the wanting period of bioactive molecules loaded in biodegradable polymers for the local delivery of drug. The drug release is affected by many factors such as hydrophilicity of drug, electric charge of drug, drug loading amount, polymer molecular weight, the monomer composition, the size of implants, the applied fabrication techniques, and so on. It is well known that the commercialization of new drug needs a lot of cost of money (average: over 10 million US dollar per one drug) and time (average: above 9 years) whereas the development of DDS and high effective generic drug might be need relatively low investment with a short time period. Also, one core technology of DDS can be applicable to many drugs for the market needs. From these reasons, the DDS research on potent generic drugs might be suitable for less risk and high return.

A Study on the Influence of Characteristics of Service Nature Dynamic Capability on Organizational Innovation of Small and Medium size Manufacturing Firms (서비스 본질 특성과 동태적 역량이 중소제조기업의 조직혁신에 미치는 영향)

  • Lee, JeungSun;Kim, Hyunsoo
    • Journal of Service Research and Studies
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    • v.8 no.1
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    • pp.27-39
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    • 2018
  • This study is an empirical study to examine the effect of the characteristics of service nature of Korean small and medium manufacturing firms on organizational innovation. It is essential to know service in order for Korea, which has a strong image as a fast follower, to enhance the competitiveness of Small and Medium size Manufacturing firms. By analyzing the service characteristics phenomenon, it is possible to understand the service nature characteristics and to strengthen the capacity to meet them. In order to gain a new resource while achieving organizational innovation, the manufacturing industry can produce new demand for the main products with competitive advantage. The characteristics of service nature are derived from relationship, equality, interactivity, and experiential value. In order to enhance the competitiveness of small and medium size manufacturing firms, core competencies required for organizational innovation are set as dynamic competencies, and to prove it. The dynamic capacity was found to affect the relationship, interactivity, and experience value. It is proved that it is an important factor to promote organizational innovation as a capability to identify and actively utilize organizational innovation opportunities ahead of competitors in a rapidly changing environment. It is needed to confirm that large corporations, midsize companies, and overseas companies can achieve the same results.

The Effects of Design Thinking in High School Chemistry Classes (디자인씽킹 기반 고등학교 화학 수업의 효과 연구)

  • Yang, Heesun;Kim, Mi-Yong;Kang, Seong-Joo
    • Journal of the Korean Chemical Society
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    • v.64 no.3
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    • pp.159-174
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    • 2020
  • The purpose of this study is to examine 'Design Thinking' based Chemistry Class program as an education strategy for core competence of creative convergence talent. The program stages were modified and supplemented into eight stages, including 'Knowledge Understand', 'Empathy', 'Sharing perspective', 'Ideate', '1st Prototype', '1st Test', '2nd Prototype', and '2nd Test', so that the 'Design Thinking Process in Science Education' can be applied to the chemistry class. Considering the linkage between the 2015 and 2009 revised national curriculum, the achievement criteria were selected, and the lesson plans and student activity sheet were developed according to the themes to be met. Four thematic educational programs were developed and applied to Chemistry I for the second grade of high school students from March to August. The results were verified through qualitative data analysis of the class scene and pre- and post-test based on inventories of 'Empathy' 'STEAM educational competence', 'Problem solving process'. As a result of applying the developed program, 'empathy' showed a significant improvement in empathy with others and empathy with the problem situation. In 'STEAM educational competence', there was a significant enhancement in science and design competence. In the 'problem finding process', the problem definition, problem solution design, and problem-solving review were significantly improved in the 'problem-solving process'. The results of this study provided implications for the applicability of design thinking - based chemistry classes and its educational effect.

Effect of Molecular Weight of PLGA on Release Behavior of Doxorubicin for Double-Layered PLGA Microspheres (PLGA 분자량에 따른 이중층 독소루비신 미립구의 방출거동)

  • Park, Jung-Soo;Yang, Jae-Chan;Yuk, Soon-Hong;Shin, Hyung-Shik;Rhee, John-M.;Kim, Moon-Suk;Lee, Hai-Bang;Khang, Gil-Son
    • Polymer(Korea)
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    • v.31 no.3
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    • pp.189-193
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    • 2007
  • We developed the doxorubicin-loaded PLGA double-layered microspheres using relatively simple oil-in-water (O/W) solvent evaporation method for sustained release of doxorubicin and investigated the release behavior according to PLGA molecular weight and initial drug loading. The double-layered microsphere was characterized on the surface, the cross-section morphology, the behavior of doxorubicin release for 5 weeks by SEM and fluorescence spectrophotometer. Double-layered microspheres showed smooth surfaces and clear difference between core and outer-shell. As the PLGA molecular weight increased, the release rate of doxorubicin-loaded, double-layered microspheres decreased. These results showed that the release behaviors can be controlled by the variation of molecular weight of PLGA.

Study on the Projectile Velocity Measurement Using Eddy Current Probe (와전류 탐촉자를 이용한 총구 탄속 측정에 관한 연구)

  • Shin, Jungoo;Son, Derac
    • Journal of the Korean Magnetics Society
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    • v.25 no.3
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    • pp.83-86
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    • 2015
  • Nowadays the weapon systems are employed air bursting munition (ABM) as smart programmable 40 mm shells which have been developed in order to hit the target with programmed munition that can be air burst after a set distance in the battlefield. In order to improve the accuracy of such a bursting time, by measuring the speed of the munition from the barrel, weapon systems calculate the exact time of flight to the target and then the time information must be inputted to the munition. In this study, we introduce a device capable of detecting a shot at K4 40 mm automatic grenade. The shot is composed of a rotating copper band to convert linear motion into rotary motion when it passes through the barrel, the steel section is exert the effect of fragment and aluminum section to give fuze information. The aluminum section was used to detect munition using eddy current method. To measure muzzle velocity by means of non-contact method, two eddy current probes separated 10 cm was employed. Time interval between two eddy current probe detection times was used as muzzle velocity. The eddy current probe was fabricated U-shape Mn-Zn ferrite core with enamelled copper wire, and 200 kHz alternating current was used to detect inductance change. Measured muzzle velocity using the developed sensor was compared to the Doppler radar system. The difference was smaller than 1%.

Neuropsychological Approaches to Mathematical Learning Disabilities and Research on the Development of Diagnostic Test (신경심리학적 이론에 근거한 수학학습장애의 유형분류 및 심층진단검사의 개발을 위한 기초연구)

  • Kim, Yon-Mi
    • Education of Primary School Mathematics
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    • v.14 no.3
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    • pp.237-259
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    • 2011
  • Mathematics learning disabilities is a specific learning disorder affecting the normal acquisition of arithmetic and spatial skills. Reported prevalence rates range from 5 to 10 percent and show high rates of comorbid disabilities, such as dyslexia and ADHD. In this study, the characteristics and the causes of this disorder has been examined. The core cause of mathematics learning disabilities is not clear yet: it can come from general cognitive problems, or disorder of innate intuitive number module could be the cause. Recently, researchers try to subdivide mathematics learning disabilities as (1) semantic/memory type, (2) procedural/skill type, (3) visuospatial type, and (4) reasoning type. Each subtype is related to specific brain areas subserving mathematical cognition. Based on these findings, the author has performed a basic research to develop grade specific diagnostic tests: number processing test and math word problems for lower grades and comprehensive math knowledge tests for the upper grades. The results should help teachers to find out prior knowledge, specific weaknesses of students, and plan personalized intervention program. The author suggest diagnostic tests are organized into 6 components. They are number sense, conceptual knowledge, arithmetic facts retrieval, procedural skills, mathematical reasoning/word problem solving, and visuospatial perception tests. This grouping will also help the examiner to figure out the processing time for each component.