• Journal of Korea Entertainment Industry Association
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• v.14 no.8
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• pp.407-426
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• 2020

The purpose of this study was to make convergent and combined analysis of the sport industry and exercise rehabilitation in the era of New Normal based on the Fourth Industrial Revolution and devise a comprehensive plan for future activation. For this purpose, literature review was performed mainly by analyzing the environment of the sport industry in the New Normal era based on the Fourth Industrial Revolution and by carrying out convergent and combined analysis of the sport industry to present a convergent and combined activation plan for exercise rehabilitation comprehensively as follows: First, it is necessary to make a strategy of promoting exercise rehabilitation in convergent and combined ways at the sport industry level. This means development of a convergent and combined exercise rehabilitation-tourism-ICT model as well as a convergent and combined exercise rehabilitation-ICT model through collaboration among ministries, including those of health and sports. Second, it is necessary to convert into a convergent and combined way of thinking and extend and reinforce educational competitiveness in the area of exercise rehabilitation. That is, it is necessary to refine the education and training systems for reinforcing personal ICT competence of exercise rehabilitation majors and relevant ones and provide convergent and combined business commencement education. Third, it is necessary to make different types of research and development by applying practical, convergent and combined skills based on the industrial field to exercise rehabilitation and relevant areas. Efforts should be made to overcome any risk in the era of New Normal and support business commencement with convergent and combined skills for exercise rehabilitation. Fourth, it is necessary to make mid- and long-term clusters where exercise rehabilitation and relevant businesses can be accumulated. This means building an industrial hub and complex for exercise rehabilitation and requires making an R&D-based cluster with industrial-academic-governmental collaboration, maximizing the synergy effects with local infrastructures, and fulfilling the function of realizing a spontaneous profit-generating structure.

• Bulletin of the Korean Chemical Society
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• v.32 no.3
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• pp.909-914
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• 2011

An improved convergent and economical method has been developed for the synthesis of erlotinib, a 4-anilinoquinazoline and an EGFR-tyrosine kinase inhibitor for treatment of non-small-cell lung cancer. The final two steps for the formation of this 4-anilinoquinazoline from suitable 2-aminobenzonitrile intermediate and 3-ethynylaniline were modified and were performed in a simple one-pot reaction. The ring-closing mechanism for the formation of erlotinib from the suitable formamidine intermediate and 3-ethynylaniline was investigated and determined to proceed via the formation of phenyl benzamidine intermediate rather than involving Dimroth rearrangement reported earlier. The new benzamidine intermediate was isolated for the first time and characterized.

• Applied Microscopy
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• v.36 no.spc1
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• pp.47-56
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• 2006

Improvements are made to existing primitive cell volume measurement method to provide a real-time analysis capability for the phase analysis of nanocrystalline materials. Simplification is introduced in the primitive cell volume calculation leading to fast and reliable method for nano-phase identification and is applied to the phase analysis of Mo-Si-N nanocoating layer. In addition, comparison is made between real-time and film measurements for their accuracy of calculated primitive cell volume values and factors governing the accuracy of the method are determined. About 5% accuracy in primitive cell determination is obtained from camera length calibration and this technique is used to investigate the cell volume variation in WC-TiC core-shell microstructure. In addition to chemical compositional variation in core-shell type structure, primitive cell volume variation reveals additional information on lattice coherency strain across the interface.

• Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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• v.5 no.4
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• pp.683-691
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• 2015

The purpose of this paper is to determine the actual strategies used in Inventory Management in the field of Distribution phenomenon. In the first part of the research, theoretical backgrounds will be reviewed in order to provide better understanding the importance of Inventory Management in Distribution Management. The qualitative data were gathered by face to face interviews and a phone interview from four selected intermediaries. The study finds intermediaries practicing JIT in the sales and distribution and maximizing the sales activities and minimizing the inventory cost by giving up on an opportunity cost.

• Journal of Ginseng Research
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• v.40 no.1
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• pp.18-27
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• 2016

Background: It is not clear whether ginseng affects cyclosporine A (CsA)-induced desirable immunosuppressive action. In this study, we evaluated the immunological influence of combined treatment of ginseng with CsA. Methods: Using CD4+ T cells from mouse spleens stimulated with the T cell receptor (TCR) or allogeneic antigen-presenting cells (APCs), we examined the differentiation of naïve T cells into T helper 1 (Th1), Th2, Th17, and regulatory T cells (Tregs), and their cytokine production during treatment by Korean Red Ginseng extract (KRGE) and/or CsA. The influence of KRGE on the allogeneic T cell response was evaluated by mixed lymphocyte reaction (MLR). We also evaluated whether signal transducer and activator of transcription 3 (STAT3) and STAT5 are implicated in this regulation. Results: Under TCR stimulation, KRGE treatment did not affect the population of CD4+interferon gamma ($IFN{\gamma}$)+ and CD4+interleukin (IL)-4+ cells and their cytokine production compared with CsA alone. Under the Th17-polarizing condition, KRGE significantly reduced the number of CD4+IL-17+ cells and CD4+/phosphorylated STAT3 (p-STAT3)+ cells, but increased the number of CD4+CD25+forkhead box P3 (Foxp3)+ cells and CD4+/p-STAT5+ cells compared with CsA alone. In allogeneic APCs-stimulated CD4+ T cells, KRGE significantly decreased total allogeneic T cell proliferation. Consistent with the effects of TCR stimulation, KRGE reduced the number of CD4+IL-17+ cells and increased the number of CD4+CD25+Foxp3+ cells under the Th17-polarizing condition. Conclusion: KRGE has immunological benefits through the reciprocal regulation of Th17 and Treg cells during CsA-induced immunosuppression.

• Journal of Microbiology and Biotechnology
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• v.26 no.3
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• pp.441-451
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• 2016

Squalene is a linear triterpene formed via the MVA or MEP biosynthetic pathway and is widely distributed in bacteria, fungi, algae, plants, and animals. Metabolically, squalene is used not only as a precursor in the synthesis of complex secondary metabolites such as sterols, hormones, and vitamins, but also as a carbon source in aerobic and anaerobic fermentation in microorganisms. Owing to the increasing roles of squalene as an antioxidant, anticancer, and anti-inflammatory agent, the demand for this chemical is highly urgent. As a result, with the exception of traditional methods of the isolation of squalene from animals (shark liver oil) and plants, biotechnological methods using microorganisms as producers have afforded increased yield and productivity, but a reduction in progress. In this paper, we first review the biosynthetic routes of squalene and its typical derivatives, particularly the squalene synthase route. Second, typical biotechnological methods for the enhanced production of squalene using microbial cell factories are summarized and classified. Finally, the outline and discussion of the novel trend in the production of squalene with several updated events to 2015 are presented.

• Journal of Korea Multimedia Society
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• v.24 no.4
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• pp.569-582
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• 2021

Education emphasizes problem-solving skills based on convergent thinking power in an era of rising uncertainty and rapid progress. This paper proactively designed e-Learning team teaching convergence liberal arts courses for prospective teachers by these social needs. It analyzed the empirical effects on the operation of the subjects to foster future talent who can converge and apply knowledge in various fields. The curriculum consisted of professors of mathematics, practical Arts, computer, and education, and was operated to convey convergent knowledge of information technology and humanities, and consisted of 15 liberal arts courses at J University. Besides, textbooks and teaching materials were also developed by the faculty. As a result of the primary research, prospective teachers who took the course generally showed high satisfaction with the class, especially for the faculty. The students' overall convergent thinking ability has increased to a statistically significant level (p<.01), and the students' major has been found to be irrelevant. On the other hand, it can be seen that communication, content convergence, and caring factors, excluding creativity factor, have all risen to a significant level.

• Journal of Engineering Education Research
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• v.20 no.3
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• pp.3-12
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• 2017

This research points out the necessity of customized communication education for engineering students in the era of the Fourth Industrial Revolution. This paper also points out such problems of current communication education as presentation and discussion-focused 'Public Speech' exercises, absence of interests about social issues, and lack of interactive communication learning. In general, as the characteristics of their major education, engineering students are not aggressive in self-questioning and active communication rather than their sensitive reaction to the changes of the new era. Considering these characteristics of engineering students, this research emphasizes that future communication education should be deployed from the major-focused thinking to the development of convergent thinking, from the problem-solving to the problem-finding, and from the contentious thinking to the cooperative thinking. In addition, as a class design reflecting future trends, this research emphasizes, firstly the development of cooperative communication education model, secondly active utilization of SMART technology, and lastly the importance of customized-coaching for each student considering their own characteristics and requirements.

• The Journal of the Korea Contents Association
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• v.14 no.4
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• pp.513-521
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• 2014

The purpose of this research is to develope and implement a convergent educational contents based on theoretical background of integrated education using agent based modeling in the ubiquitous learning environment. The structure of this contents consists of three modules that were designed by trans-disciplinary concept and situated learning theory. These three modules are: convergent problem presenting module, resource of knowledge module and learning of agent based modeling and IT tools module. After the satisfaction survey of the implemented content, out of 5 total value, the average value was 3.86 for effectiveness, 4.13 for convenience and 3.86 for design. The result of the survey shows that the users are generally satisfied. By using this u-learning contents, learners can experience and learn how to solve the convergent problem by utilizing IT tools without any limitation of device, time and space. At the same time, the proposal of structural design of contents can be a good guideline to the researchers to develop the convergent educational contents in the future.

• Journal of the Korea Convergence Society
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• v.7 no.1
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• pp.77-87
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• 2016

Objectives : The purpose of this study was to find a constructive way of the Breast Self-Examination teaching methods, identify experience who religious women participated in breast self-examination. Method : This study is a qualitative study using focus group interview method. Women religious took Breast Self-Examination program based on Problem Based Learning procedure. Results : Major Four Themes were derived. 'Breast cancer awareness', 'Breast Self Examination awareness', 'Convergence of PBL and practice on BSE experience', 'Change after convergent BSE education'. Conclusion : Women religious who have risk factors for breast cancer, want to improve the irregularities and to raising skills of BSE for self healthcare ability through convergent BSE education program for women religious.