• Journal of Life Science
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• v.28 no.2
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• pp.176-186
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• 2018

In this study, the total polyphenol contents, antioxidant activities and anti-proliferation effects of HepG2 cell lines in organic slovent fractions obtained from the main methanolic extract of P. yezoensis were analyzed. The polyphenol content of the $CHCl_3$ fraction was $10.3{\mu}g/mg$, slightly less than $13.08{\mu}g/mg$ of the water fraction, but $ED_{50}$ estimated by measuring DPPH free radical scavenging activity exhibited the highest $16.96{\mu}g/ml$ in the $CHCl_3$ fraction. The proliferation effects of $CHCl_3$ and EtOAc fraction toward HepG2 cells inhibited in a dose-dependent manner, showed 90% inhibition when treated for 24 hr at $900{\mu}g/ml$ of $CHCl_3$ fraction. Meanwhile gene expression patterns in HepG2 cells treated $50{\mu}g/ml$ of $CHCl_3$ fraction were identified with microarray analysis. Concerning the efficacy of P. yezoensis, gene ontology analysis explored the genes associated with response to molecule of bacterial origin, vitamin D metabolic process, and response to nutrient. Thus IL6R, CYP1A1 were selected as significant genes based on expression patterns of HepG2 cells, and pathway analysis indicates that ARNT might be considered as a upstream regulator. Also, expression analysis of IL6R and CYP1A1, activity of upstream regulator ARNT in HepG2 cells was confirmed based on Western blotting analysis at the protein level after being treated with 50 and $100{\mu}g/ml$ of $CHCl_3$ fraction.

• The Journal of the Korea Contents Association
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• v.18 no.7
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• pp.560-576
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• 2018

Plato's ontology is closer to Holism, which is based on IDEA, than to Dualism, which regards the matter and soul as being independently from each other. According to his metaphysics, the sensory things are the copies of IDEA. and IDEA is the original of them. Hence human body and soul are not separate from each other, but are ontologically continuous and functionally complementary. The reason why Plato's view of education, which pursues the perfection of the soul, emphasizes the physical training and makes it the premise of study is this ontology. It seems that Park Eun-sik, an independent activist in the late period of Joseon Dynasty, has a view of education similar to Plato's. He emphasized the importance of education on martial art in order to restore the our people's inner quality, 'Mind(心)'. Both Plato and Park Eun-sik thoughts that the education of physical training and martial art was the premise of study to make the humanity they pursued. And they expected that the talented people raised through the curriculum proposed by them would lead the prosperity of the nation by fulfilling their respective roles in society. In conclusion, from the view of Plato and Park Eun-sik's thoughts, it can be said that, the education of physical training and martial art for students is the premise of the study for personal perfection of human beings, and essential curriculum for making the ideal state that they dreamed.

• The Journal of the Korea Contents Association
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• v.10 no.11
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• pp.20-29
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• 2010

The typical Kinetic Family Drawing (KFD) Web database system, a form of prototype system, has been developed, relying on the suggestions from family art therapists, with an aim to handle large amounts of assessment data and to facilitate effective implement of assessment activities. However, unfortunately such a system has an intrinsic problem that it fails to collect clients' behaviors, attitudes, facial expressions, voices, and other critical information observed while they are drawing. Accordingly we propose the ontology based video event analysis and video retrieval system in this paper, in order to enhance the function of a KFD Web database system by using a web camera and drawing tool. More specifically, a newly proposed system is designed to deliver two kinds of services: the client video retrieval service and the sketch video retrieval service, accompanied by a summary report of occurred events and dynamic behaviors relative to each family member object, respectively. The proposed system can support the reinforced KFD assessments by providing quantitative and subjective information on clients' working attitudes and behaviors, and KFD preparation processes.

• The Journal of the Korea Contents Association
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• v.10 no.10
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• pp.54-67
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• 2010

Applying the conventional machine-learning method which has been frequently used in health-care area has several fundamental problems for modern U-health service analysis. First of all, we are still lack of application examples of the traditional method for our modern U-health environment because of its short term history of U-health study. Second, it is difficult to apply the machine-learning method to our U-health service environment which requires real-time management of disease because the method spends a lot of time in the process of learning. Third, we cannot implement a personalized U-health diagnosis system using the conventional method because there is no way to assign weights on the disease-related variables although various kinds of machine-learning schemes have been proposed. In this paper, a novel diagnosis scheme PCADP is proposed to overcome the problems mentioned above. PCADP scheme is a personalized diagnosis method and it makes the bio-data analysis just a 'process' in the U-health service system. In addition, we offer a semantics modeling of the U-health ontology framework in order to describe U-health data and service specifications as meaningful representations based on this PCADP. The PCADP scheme is a kind of statistical diagnosis method which has characteristics of flexible structure, real-time processing, continuous improvement, and easy monitoring of decision process. Upto the best of authors' knowledge, the PCADP scheme and ontology framework proposed in this paper reveals one of the best characteristics of flexible structure, real-time processing, continuous improvement, and easy monitoring among recently developed U-health schemes.

• The Journal of the Korea Contents Association
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• v.10 no.11
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• pp.10-19
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• 2010

The progress of computers and Web has given rise to a rapid increase of the quantity of the useful information, which is making the demand of recommender systems widely expanding. Like in other domains, a recommender system in a digital library is important, but there are only a few studies about the recommender system of research papers, Moreover none is there in korea to our knowledge. In the paper, we seek for a way to develop the NDSL recommender system of research papers based on the survey of related studies. We conclude that NDSL needs to modify the way to collect user's interests from explicit to implicit method, and to use user-based and memory-based collaborative filtering mixed with contents-based filtering(CF). We also suggest the method to mix two filterings and the use of personal ontology to improve user satisfaction.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.27 no.4
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• pp.229-249
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• 2016

This study was conducted to create a digital archive for local cultural contents compiled from the records of westerners who stayed in Korea during the Enlightenment Period of Chosun. The compiled information were gathered from 22 records, and 10 main subjects, 40 sub-subjects and 239 mini-subjects were derived through the subject classification scheme. Item analysis was conducted through 38 metadata and input data types were classified and databased in Excel. Finally, a web-based digital archiving system was developed for searching and providing information through various access points. Suggestions for future research were made to expand archive contents through continuous excavation of westerners' records, to build an integrated information system of Korean digital archives incorporating individual archive systems, to develop standardization of classification schemes and a multidimensional classification system considering facet structure in cultural heritage areas, to keep consistency of contents through standardization of metadata format, and to build ontology using semantic search functions and data mining functions.

• The Journal of the Korea Contents Association
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• v.14 no.4
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• pp.418-424
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• 2014

This paper aim; to develop the National R&D Information Navigation System(NRnDINS) that is convenient and easy to use by the researchers on the basis of information filtering and visualization by converging and integrating the three types of the contents, namely, paper, report and project at the stage of development of the information system An information system is developed by establishing ontology and RDF on the three types of contents, and by applying information filtering and semantic search technology after having created the prototype for the screen by reflecting the user needs analysis and information visualization elements surveyed at the previous stage of information service planning. In this paper, to make the measure for information filtering, R&D navigation index is prosed and implemented, and NRnDINS capable of integrated search of the R&D contents through information visualization is developed. Also, for the testing of the developed system, the preference survey for its design by 1m persons and usability test of the system by 10 users are performed The result of the survey on the preference for the design is affirmative with 85% of the subjects finding it favorable and the composite receptivity is good with the score of 87.2 the results of the usability test. However, it was also found that further development of the personalization functions is needed. It is hoped that the R&D navigation index of the proposed and implemented in this paper would present quantitative objectivity and will induce further development of other information filtering index of contents in the future.

• Proceedings of the Korea Contents Association Conference
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• 2006.11a
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• pp.218-222
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• 2006

In making 3D animation with digital technology, it is necessary to increase productivity and reusability by managing production pipeline systematically through standardization of animation content. For this purpose, we try to develop the animation content management system that can manage all kind of information on the production pipeline, based on SCORM of e-teaming by considering production, publication and re-editing. A scene as the unit of visual semantics is standardize into an object that contains meta-data of place, cast, weather, season, time and viewpoint about the scene. The meta-data of content includes a lot of information of copyright, publication, description, etc, so that it plays an important role on the management and the publication. If an effective management system of meta-data such as ontology will be implemented, it is possible to search multimedia contents powerfully. Hence, it will bring on production and publication of UCC. Using the meta-data of content object, user and producer can easily search and reuse the contents. Hence, they can choose the contents object according to their preference and reproduce their own creative animation by reorganizing and packaging the selected objects.

• Journal of Digital Convergence
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• v.10 no.10
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• pp.307-312
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• 2012

For semantic search methods to provide more accurate results than keyword-based search in a logical representation that uses a knowledge base are being studied. Than most of the user to use formal query language and schema used to interpret the meaning of a user keyword. In this paper, we propose to expand the user query for semantic search. In the proposed system, user query expansion component and a component to adjust the results to interpret user queries to take advantage of the knowledge base associated with a search term. Finally, a user query semantic interpretation, the proposed scheme to verify the experimental results of the prototype system is described.

• Journal of KIISE:Databases
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• v.32 no.6
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• pp.585-592
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• 2005

The Semantic Web is being studied as the next step in the evolution of the web. In the environment of the Semantic Web, the information must be understandable computers as well as a just human. So we use ontologies for describing the contents of the web resources. Among such ontologies, OWL is proposed as a recommendation by W3C. OWL data is represented as graph structure and the query is evaluated by traversing each node of the graph. In this paper, we propose the optimization technique based on signature to efficiently process the OWL data. Our approach minimizes traversing each node of the graph in query processing.