• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2016년도 추계학술대회
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• pp.187-188
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• 2016

국내에서는 게임물등급위원회 초창기부터 사행성에 대한 규제가 시행되고 있었으며, 현재 게임 산업에 맞게 이에 대한 규제들이 개선되거나 신설 또는 삭제되고 있다. 아케이드 게임에서 규제 되고 있는 것은 시간 당 1만 원을 초과하여 투입할 수 없고, 자동으로 진행할 수 없으며, 결과에 대하여 저장이 불가능한 점과 환전을 금지하고 있는 것이다. 본 연구는 국내의 아케이드 사행성 게임제도의 불필요한 규제, 이중 규제 등 과도한 규제안을 현실적으로 완화하고자 하였다. 이에 본 논문을 통하여 한국인의 의식 수준에 맞는 사행성 게임 규제안을 시행하는데 기여하고자 한다.

• Animal cells and systems
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• 제1권1호
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• pp.151-155
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• 1997

Promoter of the Drosophila proliferating cell nuclear antigen (PCNA) gene contains DRE (Drosophila DNA replication-related element) required for the high level expression of replication-related genes. Recently, we found that promoter region of the D-raf (a Drosophila homolog of the human c-raf-1) contains two sequences homologous to the DRE and demonstrated the DRE/DREF (DRE-binding factor) involvement in regulation of the D-raf gene. In this study, using ursolic acid (UA), a pentacyclic triterpene acid reported to possess antitumor activities, we examined effects of UA on proliferation of the Drosophila cultured Kc cells and on expression of the PCNA and D-raf genes. UA showed an inhibitory effect on proliferation of the Kc cells in a concentration-dependent manner in DNA content assays and [3H]thymidine incorporation assays. The IC50 value of anti-proliferative effects of UA in DNA content assays was about 7.5uM. UA showed inhibitory effects on expression of the PCNA as well as on that of the D-raf, which were examined with the reporter plasmic p5'-168DPCNACAT or p5'-878DrafCAT, respectively. The results obtained in the present study suggest that expression of the PCNA and D-raf genes is coordinately regulated in at least UA-treated Kc cells and that down-regulation of expression of the PCNA and D-raf genes might be related with the antitumor activities of UA.

• 운동과학
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• 제26권3호
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• pp.229-237
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• 2017

PURPOSE: This study was to investigate the Glycolysis mediated sarcoplasmic reticulum (SR) $Ca^{2+}$ signal regulates mitochondria $Ca^{2+}$ during skeletal muscle contraction by using glycolysis inhibitor. METHODS: To examine the effect of Glycolysis inhibitor on SR and mitochondria $Ca^{2+}$ content, we used skeletal muscle fiber from gastrocnemius muscle. 2-deoxy glucose and 3-bromo pyruvate used as glycolysis inhibitor, it applied to electrically stimulated muscle contraction experiment. Intracellular $Ca^{2+}$ content, SR, mitochondria $Ca^{2+}$ level and mitochondria membrane potential (MMP) was detected by confocal microscope. Mitochondrial energy metabolism related enzyme, citric acid synthase activity also examined for mitochondrial function during the muscle contraction. RESULTS: Treatment of 2-DG and 3BP decreased the muscle contraction induced SR $Ca^{2+}$ increase however the mitochondria $Ca^{2+}$ level was increased by treatment of inhibitors and showed and overloading as compared with the control group. Glycolysis inhibitor and thapsigargin treatment showed a significant decrease in MPP of skeletal muscle cells compared to the control group. CS activity significantly decreased after pretreatment of glycolysis inhibitor during skeletal muscle contraction. These results suggest that regulation of mitochondrial $Ca^{2+}$ levels by glycolysis is an important factor in mitochondrial energy production during skeletal muscle contraction CONCLUSIONS: These results suggest that mitochondria $Ca^{2+}$ level can be regulated by SR $Ca^{2+}$ level and glycolytic regulation of intraocular $Ca^{2+}$ signal play pivotal role in regulation of mitochondria energy metabolism during the muscle contraction.

• 한국콘텐츠학회논문지
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• 제11권7호
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• pp.192-209
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• 2011

본 연구는 미디어 시장에서 종합편성채널 도입이 확정된 이후 지역 지상파방송사들의 대응전략을 살펴보았다. 종합편성채널 등장으로 시장경쟁력이 취약한 지역 지상파방송은 제한된 광고시장에서 더욱 생존의 어려움에 내몰린다. 그리고 지역 지상파방송은 규제의 측면에서 종합편성채널에 비해 차별적 적용을 받는다. 의무재송신, 방송권역, 편성규제, 광고규제, 방송발전기금 등에서 역차별을 받고 있다. 이에 지역 지상파 방송사는 어려운 미디어 환경에서 다각적인 대응전략이 필요하다. 무엇보다도 경쟁력 있는 콘텐츠 강화가 절실할 때이다. 그러기에 콘텐츠 유통구조를 다원화할 필요가 있다. 지역방송의 유통구조를 확대하기 위한 방법으로, 전국 네트워크 프로그램에 지역프로그램 편성총량제 도입이 강조된다. 지역방송사가 제작한 프로그램이 주시청시간대에 전국 네트워크를 통해 정규적으로 방송될 수 있도록 하는 의무화정책이 그 예이다. 또한 독자적인 우수한 콘텐츠개발로 2차 유통창구의 다원화가 필요하다. 각 지역방송사와 SO 등 다양한 플랫폼에 공급할 수 있도록 해야 한다. 또한 지역방송사간 권역 간, 권역별 공동제작 프로그램을 활성화시킬 필요가 있다. 중앙사와 지역 방송사 간 전파료를 현실적으로 분배해야 하고 지역방송 자체적으로도 수익모델을 광고 이외에 협찬과 자체사업을 확대하여 경쟁력을 강화시켜 자생력을 키워 나가야 할 것이다. 그리고 광역화를 통해 규모의 경제를 확대해야 할 것이다.

• Journal of Korean Dental Science
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• 제10권1호
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• pp.10-21
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• 2017

Purpose: The purpose of this study was to investigate the electrochemical characteristics of nanotubular Ti-25Nb-xZr ternary alloys for dental implant materials. Materials and Methods: Ti-25Nb-xZr alloys with different Zr contents (0, 3, 7, and 15 wt.%) were manufactured using commercially pure titanium (CP-Ti), niobium (Nb), and zirconium (Zr) (99.95 wt.% purity). The alloys were prepared by arc melting in argon (Ar) atmosphere. The Ti-25Nb-xZr alloys were homogenized in Ar atmosphere at $1,000^{\circ}C$ for 12 hours followed by quenching into ice water. The microstructure of the Ti-25Nb-xZr alloys was examined by a field emission scanning electron microscope. The phases in the alloys were identified by an X-ray diffractometer. The chemical composition of the nanotube-formed surfaces was determined by energy-dispersive X-ray spectroscopy. Self-organized $TiO_2$ was prepared by electrochemical oxidation of the samples in a $1.0M\;H_3PO_4+0.8wt.%$ NaF electrolyte. The anodization potential was 30 V and time was 1 hour by DC supplier. Surface wettability was evaluated for both the metallographically polished and nanotube-formed surfaces using a contact-angle goniometer. The corrosion properties of the specimens were investigated using a 0.9 wt.% aqueous solution of NaCl at $36^{\circ}C{\pm}5^{\circ}C$ using a potentiodynamic polarization test. Result: Needle-like structure of Ti-25Nb-xZr alloys was transform to equiaxed structure as Zr content increased. Nanotube formed on Ti-25Nb-xZr alloys show two sizes of nanotube structure. The diameters of the large tubes decreased and small tubes increased as Zr content increased. The lower contact angles for nanotube formed Ti-25NbxZr alloys surfaces showed compare to non-nanotube formed surface. The corrosion resistance of alloy increased as Zr content increased, and nanotube formed surface showed longer the passive regions compared to non-treatment surface. Conclusion: It is confirmed that corrosion resistance of alloy increased as Zr content increased, and nanotube formed surface has longer passive region compared to without treatment surface.

• 한국콘텐츠학회논문지
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• 제19권7호
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• pp.199-210
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• 2019

2010년 운동경기 중계방송에 한해 도입되었던 가상광고는 2015년 지상파 방송사의 스포츠 뉴스와 예능, 드라마 프로그램에까지 확대 허용되었다. 이러한 광고 규제 완화조치로 방송사업자들은 다양한 형태의 가상광고를 프로그램에 삽입시키고 있다. 가상광고에 대한 규제가 많이 완화되었다고는 하지만 외국에 비해서는 아직 부족하고, 앞으로 성장할 가능성이 높다. 이에 본 연구에서는 문헌 연구를 통해 외국의 가상광고의 현황을 파악하여, 우리나라 가상광고가 나아갈 방향을 모색하였다. 또한 가상광고 전문가 7명과의 심층인터뷰를 통해 가상광고의 긍정적인 면과 부정적인 면을 살펴보았으며, 가상광고의 현황과 문제점을 파악하였다. 그리고 가상광고의 규제 및 심의에 대해서 분석했으며, 마지막으로 가상광고 활성화에 대한 전략을 파악하였다. 연구결과 가상광고 활성화를 위해서는 먼저 시청자들의 가상광고 관련 호감도를 높이는 것이 필요하다. 또한 가상광고 규정의 명확화가 필요하며, 심의기관을 일원화하는 것이 급선무라 할 수 있다. 아울러 광고주에게 광고효과에 대한 데이터를 제공하며, 광고 규제를 완화해야 한다. 더불어 새로운 기법이나 크리에이터에 대한 개발이 요구된다. 이에 본 연구는 새로 개정된 법에 따른 가상광고 시장의 확대를 위한 방법론과 대안과 함께 가상광고에 대한 활성화 방안을 제시하였다.

• 대한영양사협회학술지
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• 제4권2호
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• pp.160-167
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• 1998

Current status of nutrient fortification in processed food in Korea were presented by analyzing the information shown on food labels. The obtained information was assessed by the regulations on food fortification in both Korea and other countries including Codex. The most current regulations were gathered from internet. The results are summarized as follows. 1. Major nutrients fortified were calcium, Vit C, Vit B complex, iron and fiber. The forfified foods were not limitted to certain food group with more frequent fortification in snackfoods, cereal, ramyun, retort pouch foods, milk, and youguart. The descriptive terms of nutrition label for the fortification were various including high, supplemented, added, source, fortified, and abundance though the difference among these terms were not distinct. 2. Current regulation on nutrition label requires to give the content of the fortified nutrient and % RDA. However not all of food items carry above information. Also some ingredients such as chitosan, DHA, taurine, $\omega$-3 fatty acid, chondrichin, bifidus were supplemented mainly to the snack foods which FDA(USA) does not allow to be fortified. 3. The nutrient most frequently fortified was calcium and general practice of fortification appears to follow the regulation in Korea. Presently the regulation itself is not well described, this nutient fortification can cause toxic effect. Since calcium was supplemented to wide range of food group consumers who are not conscious of the safe upper limit may intake the fortified food up to the level of 2g/day. 4. For the effective fortification in Korea, the regulation on fortification should be reformed in accordance with the international guideline Codex and the regulations in other countries especially in America and Japan.

• 한국연소학회:학술대회논문집
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• 한국연소학회 2012년도 제45회 KOSCO SYMPOSIUM 초록집
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• pp.37-38
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• 2012

Two catalyst systems with different content of precious metal coated on DOC are carefully tested in a diesel engine to investigate the emission characteristics of $NO_2$. Three types of experiment methods ($NO_2$ conversion test, ETC mode test, and BPT test) are applied to compare the performance of the two catalyst systems. All the experimental results consistently indicate that it is possible to satisfy $NO_x$ regulation by properly lowering the content of precious metal without the loss of PM removal performance.

• 한국세라믹학회지
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• 제41권5호
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• pp.353-358
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• 2004

Spray drying is a unique drying process for powder production. Spray dried product must be free-flowing in order to fill the pressing dies rapidly, especially in the ceramic production. The important powder characteristics are; the particle size distribu-tion and moisture content of the finished product that can be estimated and adjusted by the spray dryer operation, within limits, through regulation of atomizer and drying conditions. In order to estimate the moisture content of the resultant dried product, we modeled the control system of the drying process using two different Artificial Neural Network (ANN) approaches, namely the Back-Propagation Multiplayer Perceptron (BPMLP) algorithm and the Radial Basis Function (RBF) network. It was found out that the performance of both of the artificial neural network models were quite significant and the total testing error for the 100 data was 0.8 and 0.7 for the BPMLP algorithm and the RBF network respectively.

• 한국환경보건학회지
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• 제8권1호
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• pp.45-53
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• 1982

To determine the effect of r-irradiation on the microorganisms destruction and the changes of general constituents of Ginseng Powder, three samples were analyzed at 1st and 3rd month after r-irradiation. The results were as follows: 1. Total bacterial counts were decreased during storage as the irradiation dose increased. It seems that about 300 Krad was satisfactory to the regulation of ginseng powder. ($5.0 \times 10^4 /g$) 2. Coliform group was also decreased during storage as the irradiation dose increased. Coliform group was not detected at the irradiation dose higher than 500 Krad. 3. Total bacterial counts and coilform group were in proportion to the content of moisture in ginseng powder. 4. The contents of moisture, ash, crude protein, crude lipid and total sugar in ginseng powder during storage had nearly no changes. 5. The content of reducing sugar in ginseng powder during storage had the increasing tendencies as the irradiation dose increased. 6. The content of amino-nitrogen in ginseng powder during storage had the decreasing tendencies as the irradiation does increased.