• Journal of Sensor Science and Technology
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• v.20 no.3
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• pp.145-150
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• 2011

In this paper, we designed a tunable microstrip patch antenna using RF MEMS switches. The design and simulation of the antenna were performed using a high frequency structure simulator(HFSS). The antenna was designed for use in the ISM band and either operates at 2.4 GHz or 5.7 GHz achieving -10 dB return-loss bandwidths of 20 MHz and 180 MHz, respectively. In order to obtain high efficiency and improve the ease of integration, a high resistivity silicon(HRS) wafer on a glass substrate was used for the antenna. The antenna achieved high gains: 8 dB at 5.7 GHz and 1 dB at 2.4 GHz. The RF MEMS DC contact switches were simulated and analyzed using ANSYS software.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 1995.03a
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• pp.162-169
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• 1995

An improved nonparametric tool description based on successive refined monparametric patches is proposed and therlated criterion for refinement is also discussed . In the proposed sheme, any required order of tool surface conformity can be achieved by employing successive refinements accoring to the suggested criterion. By using the suggested adaptive tool refinement technique based on the nonparametric patch tool description, the locally refined nonparametric tool surface with economic memory size and sufficient accuracy as well as with favorable charateristics for contact treatment can be obtained directly form the parametric patch related with commerical CAD system. Computation is carried out for a chosen complex sheet forming example of an actual autobody panel in order to verify the validity and the efficiency of the developed tool surface description.

• Korean Journal of Computational Design and Engineering
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• v.2 no.2
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• pp.122-129
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• 1997

Ball rolling blending is a popular technique for blending between parametric surfaces. The ball rolling blend surface is conceptually a trajectory of a ball rolling between two base sufaces. It is constructed by sweeping a circular arc along a ball contact curve pair. Since a ball rolling blend surfaces does not have a polynomial form like a Bezier surface patch, it is impossible to apply this method directly to a commercial CAD/CAM system. In this paper an algorithm is developed to approximate a ball rolling blend surface into Bezier surface patches. Least square method is applied to obtain proper Bezier surface patches under a given tolerance. The Bezier surface patches have degree three or more and guarantee VC1-continuity.

• Journal of Pharmaceutical Investigation
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• v.27 no.4
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• pp.303-311
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• 1997

Proliposomal patch of clenbuterol, ${\beta}_2-agonist$ bronchodilator, was prepared and its feasibility as a novel transdermal drug delivery system was examined. Proliposomal granules containing clenbuterol was prepared by a standard method using sorbitol and lecithin with (Rx 2) or without cholesterol (Rx 1). The porous structure of sorbitol in the proliposomes was maintained allowing tree flowability of the granules. Following contact with water, the granules were converted probably to liposomes almost completely within several minutes. It indicates that proliposomes may be hydrated, when they are applied on the skin under occlusive condition in vivo, by the sweat to form liposomes. Clenbuterol release from Rx 1 and Rx 2 proliposomes to pH 7.4 isotonic phospate buffer (PBS) across cellulose membrane (mol. wt. cut-off of 12000-14000) was retarded significantly compared with that from the mixture of clenbuterol powder and blank proliposomes. Interestingly, proliposomes prepared with lecithin and cholesterol (i.e., Rx 2 proliposomes) showed much more retarded release of clenbuterol than proliposomes prepared only with lecithin (i.e.. Rx 1 proliposomes), indicating that clenbuterol release from proliposomes can be controlled by the addition of cholesterol to the proliposomes. Proliposomal patches were prepared using PVC film as an occlusive backing sheet, two sides adhesive tape (urethane, 1.45 mm thickness) as a reservoir for proliposome granules and Millipore MF-membrane (0.45 mm pore size) as a drug release-controlling membrane. Rx 1 or Rx 2 proliposomes containing 4.6 mg of clenbuterol were loaded into the reservoir of the patch. Clenbuterol release from the patches to pH 7.4 PBS was determined using USP paddle (50 rpm)-over-disc release method. Clenbuterol release from the proliposomal patches was much more retarded even than from a matrix type clenbuterol patch (Boehringer Ingelheim ltd). Being consistent with clenbuterol release from the proliposomal granules, the release from the patches was highly dependent on the presence of cholesterol in the proliposomes : Patches containing Rx 2 proliposomes showed several fold slower drug release than patches containing Rx 1 proliposomes. When the patch containing Rx 1 proliposomes was applied on to the back of a hair-removed rat, clenbuterol concentration in the rat blood was maintained during 6-72 hrs. Transdermal absorption of clenbuterol from the patch was accelerated when the patch was prehydrated with 50 ml of pH 7.4 PBS before topical application. Above results indicate that sustained transdermal delivery of clenbuterol is feasible using proliposomal patches if the cholesterol content and pore size of the release rate-controlling membrane of patches, for example, are appropriately controlled.

• Polymer(Korea)
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• v.33 no.2
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• pp.111-117
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• 2009

This study aims to verify for humans the suitability of the enzyme-fixed hydrogel used for the patch sensor of the blood sugar testing system without blood sampling, which utilizes reverse iontophoresis. Using acrylate monomers, hydrogel was synthesized to which a certain unit of enzyme is fixed. In order to analyze the material property of the synthesized hydrogel, a structural analysis was performed using FT-IR spectroscopy, while the DSC was used to verify the thermal stability. In addition, with the UV-Vis spectrophotometer, it was verified that the degree of active enzyme is at least 50% greater than the standard product. The SEM was used to verify secure fixation of the enzyme onto the surface. As a result, it was observed that the enzyme is successfully fixed to the surface. Since the hydrogel makes direct contact with a patient's skin, it is essential to evaluate the toxicity when making direct contact with the skin. For that purpose, various sets of tests were undertaken according to the ISO 10993-cytotoxicity, intracutaneous reactivity, skin irritation test and maximization sensitization. Consequently, it was successfully verified that the enzyme-fixed hydrogel have bioavailability.

• Journal of Oral Medicine and Pain
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• v.25 no.4
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• pp.355-364
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• 2000

This study was to find dental materials causing hypersensitivity reactions by carrying out patch tests in the patients with oral mucosal lesions to investigate the possibility of hypersensitivity reactions in etiology of oral mucosal lesions. 31 patients (female 26, male 5, age range 24-72 years) with oral mucosal lesions were classified as patient group, and 41 volunteers (female 24, male 17, age range 23-40 years) without oral mucosal lesion, systemic disease and history of allergy as control group. The obtained results were as follows: 1. There were various dental restorations in most of patient group and control group, 29(94%) in 31 patient group, 35(85%) in 41 control group. 2. Among sites of oral mucosal lesions, buccal mucosa was the most common site with 60%, followed by gingiva with 24%, tongue with 16%. Lesions in contact with restorations were highly 90% in tongue and 89% in buccal mucosa, but comparatively lower 53% in gingiva. 3. The ratio of positive reactions to the patch test in patient group was significantly higher than the control group (p<0.05). 4. Dental materials causing positive reactions to the patch test were mainly mercury(19%), potassium dichromate(16%), cobalt chloride(16%) in patient group, cobalt chloride(17%) in control group. 5. In 20 patients with lichen planus, 8 patients(40%) showed positive reactions to the patch test.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2002.11a
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• pp.337.2-337
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• 2002

When vehicle travelling along the track which has irregularity such as vortical profile, dynamic forces arise at the Wheel/Rail contact patch by wheel/rail interaction. In particular short wavelength irregularities on dipped joint and small stiffness of connecting rail bring about intense wheel/rail dynamic effects at higher speed. In the paper, a new model for dipped joint rail is developed to study dynamic behavior of track. (omitted)

• Journal of the Society of Cosmetic Scientists of Korea
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• v.3 no.1
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• pp.40-84
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• 1973

Synopsis-The difficulties of immunological nonienclature are discussed, the term ALLERGY defined and the various types of HYPERSENSITIVITY reactions are listed and characterized. Evidence for the association of Type I and Type 11 hypersensitivity reactions with COSMETICS is discussed. A table of cosmetic ingredients which have been implicated as SENSITIZERS are given. PREDICTIVE PATCH TESTS for contact sensitizers on GUINEA-PIGS and man are evaluated. The difficulties of testing for ALLERGENS likely to produce Type I hypersensitivity are discussed. IN VITRO tests for sensitizers are mentioned. The failure of all standard tests in the detection of weak sensitizers is emphasized.asized.

• Proceedings of the KSR Conference
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• 2000.05a
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• pp.135-142
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• 2000

This Paper describes a characteristics of wheel wear of high speed train running on the conventional line. Conventional line has many curved tracks that cause severe wheel flange wear. The influences of lubrication, cant deficiency, owe radius on wheel wear are also described considering the operation performance of the highspeed trainset. A method of calculation using contact patch work model is presented far determination of the evolution by wear of railway wheels.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2007.11a
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• pp.322-325
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• 2007

This paper suggests a non-contact sensor for measuring bending vibration of a non-metallic cylinder in two orthogonal directions simultaneously. Recent research shows that a solenoid can pick up bending vibrations of a nonmetallic cylinder based on the reversed Lorentz force mechanism if an electrical conductive patch is attached to the cylinder. In this work, pairs of specially designed patches are used to make two independent paths for the current induced by bending vibrations, which enables the measurement of bending vibrations along two orthogonal directions simultaneously. The working performance of the developed sensor was verified by using two accelerometers.