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Investigation of the efficacy of mycotoxin-detoxifying additive on health and growth of newly-weaned pigs under deoxynivalenol challenges

  • Holanda, Debora Muratori;Kim, Sung Woo
    • Animal Bioscience
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    • v.34 no.3_spc
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    • pp.405-416
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    • 2021
  • Objective: This study evaluated the effects of feeding diets naturally contaminated with deoxynivalenol (supplemental 2 mg/kg) on health, growth, and the effects of a mycotoxin-detoxifying additive in newly-weaned pigs. Methods: Thirty-six pigs (27 day-old) were housed individually and assigned to 3 treatments for 5 weeks: CON (diet containing minimal deoxynivalenol), MT (diet with supplemental 1.9 mg/kg of deoxynivalenol), and MT+D (MT + mycotoxin-detoxifying additive, 0.2%, MegaFix, ICC, São Paulo, Brazil). The mycotoxin-detoxifying additive included bentonite, algae, enzymes, and yeast. Blood was taken at week 2 and 5. Jejunal tissue were taken at week 5. Data were analyzed using the MIXED procedure of SAS. Results: Pigs fed MT+D tended to have decreased (p = 0.056) averaged daily feed intake during week 1 than MT. At week 2, serum aspartate aminotransferase/alanine aminotransferase in MT tended to be lower (p = 0.059) than CON, whereas it was increased (p<0.05) for MT+D than MT, indicating hepatic damages in MT and recovery in MT+D. Pigs fed MT had lower (p<0.05) blood urea nitrogen/creatinine than CON, supporting hepatic damage. At week 5, pigs fed MT tended to have reduced (p = 0.079) glucose than CON, whereas it was increased (p<0.05) for MT+D than MT, indicating impaired intestinal glucose absorption in MT, which was improved in MT+D. Pigs fed CON tended to have increased (p = 0.057) total glutathione in jejunum than MT, indicating oxidative stress in MT. Pigs fed MT+D had a reduced (p<0.05) proportion of Ki-67-positive cells in jejunum than MT, indicating lower enterocyte proliferation in MT+D. Conclusion: Feeding supplemental 1.9 mg/kg of deoxynivalenol reduced growth and debilitated hepatic health of pigs, as seen in leakage of hepatic enzymes, impaired nitrogen metabolism, and increase in oxidative stress. The mycotoxin-detoxifying enhanced hepatic health and glucose levels, and attenuated gut damage in pigs fed deoxynivalenol contaminated diets.

Effect of dietary salicylic acid supplementation on performance and blood metabolites of sows and their litters

  • Serge, Muhizi;Sungbo, Cho;Thanapal, Palanisamy;In Ho, Kim
    • Journal of Animal Science and Technology
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    • v.64 no.4
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    • pp.707-716
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    • 2022
  • The core intention to undertake this experiment for a period of 21 days is to evaluate the effect of salicylic acid (SA) supplemented diet on the performance and blood metabolites of sows and their litters. Sows weighing 208.5 ± 18.34kg and their neonates were used. From day 114 of gestation to 21st day of lactation(weaning), ten multiparous sows (n = 5/treatment) (Landrace × Yorkshire) were assigned randomly into one of two treatments: CON (basal diet) and TRT (CON + 0.05% SA). There was no significant difference in the body weight, backfat thickness, backfat loss, and body condition score in SA treated sows compared to sows fed the CON diet. However, the bodyweight of sow was dramatically reduced by an average of 16kg from farrowing to weaning time. The dietary inclusion of SA in the sow diet slightly improved the survival rate (p = 0.065) and showed a higher body weight (p = 0.009) in piglets. However, there was no significant difference in red blood cell, Fe, Hematocrit, and Hb concentrations between CON and TRT sows' groups, but the total iron-binding capacity (TIBC) was significantly reduced in sows from the TRT group compared with the CON group from the beginning to weaning. The outcome of this trial shows that dietary addition of SA on sows diet from early lactation could increase the birth weight and TIBC of neonates at the end of the trial.

Effects of Dietary Prebiotics and Probiotics on Growth, Immune Response, Anti-oxidant Capacity and Some Intestinal Bacterial Groups of the Red Seabream Pagrus major (사료 내 Prebiotic과 Probiotics의 첨가가 참돔(Pagrus major)의 성장, 면역력, 항산화력, 장내 미생물 조성 변화에 미치는 영향)

  • Jongho Lim;Gunho Eom;Choong Hwan Noh;Kyeong-jun Lee
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.56 no.1
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    • pp.89-98
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    • 2023
  • We evaluated the effects of prebiotic (mannan oligosaccharides, Mos) and probiotic diet supplements on growth performance, innate immunity, antioxidant activity, and intestinal changes in the microbial flora of red seabream Pagrus major. A basal diet (Con) was formulated to meet the nutrient requirement of red seabream. The dietary starch in Con was replaced with 0.6% Mos, Lactobacillus plantarum, Bacillus subtilis, B. licheniformis and probiotic mixture (labeled as Mos, Pro-LP, Pro-BS, Pro-BL and Pro-Mix, respectively). We stocked 450 fish in 18 polypropylene tanks (400 L) in triplicate groups per dietary treatment. The fish were fed one of the diets twice (08:30, 18:30 h) a day for 63 days. Lysozyme activity was significantly higher in all the supplemented groups than that of the Con group. The immunoglobulin level of Pro-Mix, anti-protease activity of Pro-BL, and glutathione peroxidase and superoxide dismutase activity of Pro-BS, Pro-BL and Pro-Mix groups were significantly higher than those of the Con group. The ratio of total Vibrio/heterotrophic marine bacteria counts was significantly lower in Pro-LP, Pro-BL and Pro-Mix groups than that of the Con group. Therefore, dietary supplementation of Mos and probiotics to improves immune response and antioxidant enzyme activity and inhibits Vibrio bacteria in the intestine.

AprilTag and Stereo Visual Inertial Odometry (A-SVIO) based Mobile Assets Localization at Indoor Construction Sites

  • Khalid, Rabia;Khan, Muhammad;Anjum, Sharjeel;Park, Junsung;Lee, Doyeop;Park, Chansik
    • International conference on construction engineering and project management
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    • 2022.06a
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    • pp.344-352
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    • 2022
  • Accurate indoor localization of construction workers and mobile assets is essential in safety management. Existing positioning methods based on GPS, wireless, vision, or sensor based RTLS are erroneous or expensive in large-scale indoor environments. Tightly coupled sensor fusion mitigates these limitations. This research paper proposes a state-of-the-art positioning methodology, addressing the existing limitations, by integrating Stereo Visual Inertial Odometry (SVIO) with fiducial landmarks called AprilTags. SVIO determines the relative position of the moving assets or workers from the initial starting point. This relative position is transformed to an absolute position when AprilTag placed at various entry points is decoded. The proposed solution is tested on the NVIDIA ISAAC SIM virtual environment, where the trajectory of the indoor moving forklift is estimated. The results show accurate localization of the moving asset within any indoor or underground environment. The system can be utilized in various use cases to increase productivity and improve safety at construction sites, contributing towards 1) indoor monitoring of man machinery coactivity for collision avoidance and 2) precise real-time knowledge of who is doing what and where.

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Physicochemical and organoleptic properties of hot-air dried oriental melon slices prepared using different physical pretreatments

  • Young Min Kim;Minhui Kim;Yujung Jung;Jiyoon Kim;Jung Soo Kim;Dong Hyun Kim;Sae-Byuk Lee;Juhyun Kim;Sang-Han Lee;Kwang-Deog Moon;Seockmo Ku;Deokyeong Choe
    • Food Science and Preservation
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    • v.31 no.2
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    • pp.218-226
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    • 2024
  • The oriental melon poses challenges in terms of long-term storage and distribution. Addressing these issues requires an extension of the storage life through appropriate processing. In this study, pretreated hot-air dried oriental melon slices (steamed and freeze-thawed) were prepared, and their physicochemical and organoleptic properties were examined. The control group (CON) consisted of hot-air dried oriental melon slices without pretreatment, while the steamed group (STG) and freeze-thawed group (FTG) consisted of hot-air dried oriental melon slices pretreated using steaming and freeze-thawing methods, respectively. The moisture contents detected in the CON, STG, and FTG groups ranged from 15.96% to 27.30%, with variations of 7.53 to 8.40 °Brix for the soluble solid contents. The CON group showed the highest Hunter color value for lightness (L*) and the lowest value for redness (a*). The texture profile analysis revealed the highest hardness and chewiness in the order of STG > CON > FTG. Considerable differences were observed in springiness and adhesiveness in the FTG group compared to the other groups. The organoleptic evaluation showed that the CON group had the highest sensory scores for overall preference. These findings indicate that the properties of hot-air dried oriental melon slices were influenced by physical pretreatments and that manufacturing these slices without pretreatment is the most effective method in terms of processing simplicity and cost efficiency.

A Study on Design of 2.45GHz and GPS antenna Integrated Board using Container security Device(ConTracer) (컨테이너 보안 장치(ConTracer)에 활용되는 2.45GHz 및 GPS 안테나 통합 보드 설계에 관한 연구)

  • Lee, Eun-Kyu;Moon, Young-Sik;Shin, Joong-Jo;Shon, Jung-Rock;Choi, Sung-Pill;Kim, Jae-Joong;Choi, Hyung-Rim
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2011.05a
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    • pp.502-505
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    • 2011
  • In this paper, A Design of 2.45GHz and GPS antenna Integrated Board using Container security Device(ConTracer) for container cargo transportation is proposed and experimentally evaluate. Integrated antenna board include 2.4GHz chip and Ceramic GPS antenna is also consider the impact of RF interference based on simulation for applied to steel container. After a careful comparison and analysis a part of the container door for its best performance, We conduct tests to characterize. The proposed integrated antenna board is suitable for container cargo transportation application in steel container field.

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Effect of Diets with Red Yeast Sweet Potato Powder Supplement on Fecal Amount and Lipid Metabolism in Rats Fed a High-fat Diet (홍국고구마가 고지방식이를 급여한 흰쥐의 배변량 및 지질대사에 미치는 영향)

  • Park, Ju-Hun;Choi, Sang-Yoon;Lee, Kyung-Won;Kim, Sung-Soo;Cho, Kyung-Dong;Han, Chan-Kyu
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.41 no.4
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    • pp.487-493
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    • 2012
  • This study was performed to investigate the effects of a diet with a red yeast sweet potato supplement on fecal amount and lipid metabolism in male Sprague-Dawley rats fed a high-fat diet for 10 weeks. Rats were fed a high-fat diet (15% fat) with additional lard (7%) and cholesterol (1%) based on AIN-93G basal diet (7% fat) for 6 weeks during the first phase. In the second phase, which lasted 4 weeks, the rats divided into four experimental groups which were composed of a high-fat diet group as a control (CON), a high-fat diet with 5% white-fleshed sweet potato supplement group (WFSP), a high-fat diet with 5% red yeast sweet potato supplement group (RYSP), and a high-fat diet with 5% purple-fleshed sweet potato supplement group (PFSP). The fecal amount of group RYSP increased significantly during the second phase compared to the other groups (p<0.05). The fecal total cholesterol (TC) and triglyceride (TG) content of group RYSP were also highest among all experimental groups. The serum TC and TG were shown to have the lowest levels in the group RYSP, and LDL-cholesterol levels were significantly decreased in groups RYSP and PFSP than in group CON (p<0.05). These results indicate that supplementation with red yeast sweet potato seemed to be effective in increasing feces and fecal lipid excretion, and also in decreasing serum lipid levels in rats fed a high-fat diet.

The Effects of Yeast Hydrolysate SCP-20 on Reproductive Function in Male Mice (효모가수분해물 SCP-20의 첨가가 웅성 마우스의 생식 기능에 미치는 영향)

  • 홍종욱;김인호;유승환;이현숙;권오석;민병준;이원백;손경승;김진만
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.33 no.2
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    • pp.451-454
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    • 2004
  • A total of forty male mice (32∼33 g average initial body weight) were used in a 10-d growth study to evaluate the effects of dietary yeast hydrolysate SCP-20 on reproductive function in male mice. Dietary treatments included 1) CON (basal diet) and 2) TRT (CON diet +1.5% yeast hydrolysate SCP-20). Testis weight of male mice fed TRT diets was higher than that of male mice fed CON diet (p<0.05). Also VSL was significantly (p<0.05) increased in male mice fed TRT diet compared to that in male mice fed CON diet. Male mice fed TRT diet showed significant (p<0.05) improvement in VAP (average-path velocity) and LIN (linearity) compared to male mice fed CON diet. Also, velocity of epididymal sperm of male mice fed TRT diets was higher than that of male mice fed CON diet (P<0.05). In conclusion, the results obtained from this trial suggests that the dietary yeast hydrolysate SCP-20 was an effective means of improving sperm velocity in male mice.

The Effect of Injinsammul-tang(IJS) on the Hepatocellular Carcinogenesis Induced by Diethylnitrosamine(DENA) in Rats (인진삼물탕(茵蔯三物湯)이 DENA로 유발된 흰쥐의 간암에 미치는 영향)

  • Jung, Tae-San;Choi, Eun-Hee;Kang, Seong-Sun;Kim, In-Soo;Lee, Young-Soo;Choi, Chang-Won
    • The Journal of Internal Korean Medicine
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    • v.32 no.3
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    • pp.397-410
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    • 2011
  • Objectives : This study was designed to investigate the effect of Injinsammul-tang (IJS) on hepatocellular carcinogenesis in rats. Methods : Sprague Dawley (SD) rats of control and treatment groups received intraperitoneal injection of 50 mg/kg/day diethylnitrosamine (DENA) weekly for 8 weeks. Experimental rats were classified into 3 groups; normal group (Nor), hepatic cancer induced control group (Con), and IJS extract 250 mg/kg administered group (IST) after being injected with DENA. Thereafter the changes of body weight, liver weight and weight of liver/100g body weight, the activities of aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), lactate dehydrogenase (LDH), and superoxide dismutase (SOD) were measured. Gross anatomy and optical microscopy were also observed. Results : The body weight decreased in Con and IST compared with the Nor. The weight of liver and the weight of liver/100g body weight increased significantly in Con and IST compared with the Nor. The activities of AST, ALT, ALP, LDH increased in the Con compared with Nor, but decreased in IST compared with Con. The activities of SOD increased in the Con and IST compared with Nor. Upon naked eye and light microscopic examination, IJS improved the morphological and histopathological changes of liver caused by DENA-induced hepatic neoplasm. The number of hepatic p53 positive cells decreased in the IST compared with Con. Conclusions : Most of the results did not show a significant effect, but some of the results showed a significant effect. It can be estimated that IJS has some effects on hepatocellular carcinogenesis induced by DENA in rats, and further studies will be needed.

Effect of Oral Sport Beverages with Medicinal Herbs Added on Short-term Recovery from Exercise-induced Fatigue (한의약소재 스포츠음료수 섭취가 운동-유발성 피로의 단시간 회복에 미치는 영향)

  • Na Hyun-Jong;Lee Kyu-Lark;Kang Ho-Youl
    • The Journal of Korean Medicine
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    • v.27 no.1 s.65
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    • pp.36-46
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    • 2006
  • Objectives : Ginseng Research Group in Korea Food Research Institute developed Saeng Mac San (KFRI-2)and Je Ho Tang (KFRI-3) with their sensory factors more acceptable. And we examined their effects on the short-term recovery capacity for cycling exercise (EX) maintained to all-out. Methods : Seven healthy young subjects (aged $24.0{\pm}2.1yr$) were volunteered at this double blind test. Each of KFRI-2, 3, a commercial sport beverage and control (CON) was offered randomly on a series of EX protocol including 65% VO2max-90min EX (D-ride). 1h-recovery and 85% VO2max EX to all-out (P-ride) under the control of their heart rate (HR) and rating perception of exertion (RPE). Blood samples were collected before D-ride, 30, 60 and 90min in D-ride, 30 and 60min in the recovery period and each 10min in P-ride. Plasma analysis items were glucose, insulin, cortisol (CORT), testosterone (TEST), free fatty acid (FFA), $Na^+$, Cl-and $K^+$. The collected data (Means${\pm}$SE) were analysed by two-way ANOVA and statistically significant differences between treatments (p<0.05) by LSD.; the significant level in FFA, $Na^+$, Cl-and $Na^+$ was p<0.01 Results : At 30min during recovery. plasma glucose level in KFRI-3 was significantly higher than CON, and also insulin in KFRI-3 was than CON and KFRI-2. FFA in KFRI-3 was significantly lower than CON during recovery. $Na^+$ in KFRI-3 significantly higher than CON at 90min in D-ride, and also KFRI-2 was at 60min during recovery. However CORT, TEST, Cl-and $Na^+$ in treated beverages were not significant. KFRI-2, 3 elevated the time for P-ride more than CON did. Conclusions : KFRI-2, 3 elevated the time for P-ride about 12% more than CON did. It is based on rapid recovery of plasma glucose level and inhibition of lipolysis during recovery.

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