• Title/Summary/Keyword: Combined application

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Stability and Effectiveness of Laser and Liquiband Treatments in the Rat Model of Oral Ulcer

  • Kang, Ji Won;Ryu, Hyun Seok;Abueva, Celine;Chung, Phil-Sang;Woo, Seung Hoon
    • Medical Lasers
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    • v.10 no.4
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    • pp.207-213
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    • 2021
  • Background and Objectives This study was undertaken to assess the stability and efficacy of laser therapy (808 nm), Liquiband (a commercial topical skin adhesive product), and a combination treatment, for application in oral ulcers. Materials and Methods The oral ulcer rat animal model was used to determine the efficacy of photobiomodulation, Liquiband, or combination therapy. Ulcers were induced by injecting 60% acetic acid in the oral mucosa. Three days after ulcer confirmation, the chemically induced ulcers were treated with either laser (808 nm), Liquiband, or a combination of both, every two days for 8 days (4 sessions). Combination therapy was performed by first treating with laser followed by application of the Liquiband. Reduction in ulcer area size was subsequently determined, and animals were sacrificed at 5 and 10 days after the last administration, for histological observation of the extracted oral ulcer tissue samples. Results In this study, treatment with either laser (808 nm) or commercial Liquiband product as well as the combined treatment significantly enhanced oral ulcer healing in the rat animal model. The effect of laser treatment is mainly attributed to collagen synthesis, whereas application of the Liquiband promotes vascularization and formation of granulation tissue. Our results indicate that further optimization of the combined therapy could synergistically and significantly enhance oral ulcer healing. Conclusion Laser or Liquiband treatment of oral ulcer in the rat animal model exert different outcomes, but both methods confirm significant effects relative to the untreated group. The combined treatment group with laser and Liquiband showed marked oral ulcer healing, but further optimization is required to get highly significant results and establish the potential synergistic effect of the combination therapy, as compared to the individual enhancing effects of healing oral ulcers.

Effect of CLT and Sling Exercise Combined Program on Knee Pain in Patellofemoral Pain Patient: A Single-Subject Study (협응이동훈련과 슬링운동 결합 프로그램이 무릎넙다리통증 환자의 무릎통증 및 기능적 움직임에 미치는 영향: 단일사례 연구)

  • Kim, Seong-hwan;Yu, Seong-hun;Park, Se-jin
    • The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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    • v.25 no.2
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    • pp.73-81
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    • 2019
  • Background: Patellofemoral pain is one of the common diseases of the musculoskeletal system. Many previous studies have recommended the application of exercise therapy to patellofemoral pain patients for treatment. The purpose of this study was to investigate effect of coordinative locomotor training (CLT) and sling exercise combined program on knee pain and functional movement in patellofemoral pain patient. Methods: In this study, single-subject design (A-B-A') was conducted for 6 weeks. A repeted-measure analysis was conducted to assess results of the anterior knee pain scale (AKPS), Clarke's test (CT), eccentric step down test (ESDT). During the intervention (B), the CLT and sling exercise combined program was conducted three times a week for 4 weeks. Results: From baseline period A to intervention period B, the AKPS, CT, ESDT were improved from 61 to 48 (27%), from 8.33 to 3 (64%), from 7.67 to 3,58 (53%). From baseline period A to baseline period A', the AKPS, CT, ESDT were improved from 70.67 to 48 (47%), from 0.67 to 3 (92%), from 1.33 to 3,58 (83%). Conclusion: Based on the results of this study, we recommend the application of CLT and sling exercise combined program to improve the pain and functional movement in patellofemoral pain patients.

Combined seismic and energy upgrading of existing reinforced concrete buildings using TRM jacketing and thermal insulation

  • Gkournelos, Panagiotis D.;Bournas, Dionysios A.;Triantafillou, Thanasis C.
    • Earthquakes and Structures
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    • v.16 no.5
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    • pp.625-639
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    • 2019
  • The concept of the combined seismic and energy retrofitting of existing reinforced concrete (RC) buildings was examined in this paper through a number of case studies conducted on model buildings (simulating buildings of the '60s-'80s in southern Europe) constructed according to outdated design standards. Specifically, seismic and thermal analyses have been conducted prior to and after the application of selected retrofitting schemes, in order to quantify the positive effect that retrofitting could provide to RC buildings both in terms of their structural and energy performance. Advanced materials, namely the textile reinforced mortars (TRM), were used for providing seismic retrofitting by means of jacketing of masonry infills in RC frames. Moreover, following the application of the TRM jackets, thermal insulation materials were simultaneously provided to the RC building envelope, exploiting the fresh mortar used to bind the TRM jackets. In addition to the externally applied insulation material, all the fenestration elements (windows and doors) were replaced with new high energy efficiency ones. Afterwards, an economic measure, namely the expected annual loss (EAL) was used to evaluate the efficiency of each retrofitting method, but also to assess whether the combined seismic and energy retrofitting is economically feasible. From the results of this preliminary study, it was concluded that the selected seismic retrofitting technique can indeed enhance significantly the structural behaviour of an existing RC building and lower its EAL related to earthquake risks. Finally, it was found that the combined seismic and energy upgrading is economically more efficient than a sole energy or seismic retrofitting scenario for seismic areas of south Europe.

Combined Application of Bacillus sp. JJ2-01 and Garlic Oil for Controlling Sclerotium rolfsii in Pepper Plants (Bacillus sp. JJ2-01과 마늘 오일 혼합처리에 의한 고추 흰비단병 억제 효과)

  • Moon, Hye Jeong;Ju, Ho-Jong;Ahn, Seong-Ho;Song, Jaekyeong;Sang, Mee Kyung
    • Korean Journal of Organic Agriculture
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    • v.30 no.3
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    • pp.409-422
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    • 2022
  • Southern blight caused by Sclerotium rolfsii is a serious soilborne disease in economically important crops including pepper. In this study, we conducted a selection of antagonistic bacterial strains and organic materials to biologically control the disease. Out of 39 strains isolated from soils at Jinju in Korea, strain JJ2-01 showed the highest mycelial growth inhibition; garlic oil among various organic materials significantly reduced disease incidence and severity. When a combination of strain JJ2-01 and garlic oil, or each was drenched into the pepper plants, combined treatment and garlic oil significantly suppressed the disease development, however, acid phosphatase activity in garlic oil-treated plants decreased. In the case of combined treatment, the soil activities did not affect by treatment, while soil urease activity was significantly increased by the combined treatment. Therefore, given soil quality and health for sustainable agriculture, the combination of strain JJ2-01 and garlic acid was an effective application for environmental-friendly control of Southern blight in pepper plants.

Optimal Microgrid Operation Considering Fuel Cell and Combined Heat and Power Generation (연료전지와 열병합 발전을 고려한 마이크로그리드의 최적 운용)

  • Lee, Ji-Hye;Lee, Byung Ha
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.62 no.5
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    • pp.596-603
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    • 2013
  • The increase of distributed power generation is closely related to interest in microgird including renuable energy sources such as photovoltaic (PV) systems and fuel cell. By the growing interest of microgrid all over the world, many studies on microgrid operation are being carried out. Especially operation technique which is core technology of microgrid is to supply heat and electricity energy simultaneously. Optimal microgrid scheduling can be established by considering CHP (Combined Heat and Power) generation because it produce both heat and electricity energy and its total efficiency is high. For this reason, CHP generation in microgrid is being spotlighted. In the near future, wide application of microgrid is also anticipated. This paper proposes a mathematical model for optimal operation of microgrid considering both heat and power. To validate the proposed model, the case study is performed and its results are analyzed.

Small scale experimental testing to verify the effectiveness of the base isolation and tuned mass dampers combined control strategy

  • Petti, Luigi;Giannattasio, Giovanni;De Iuliis, Massimiliano;Palazzo, Bruno
    • Smart Structures and Systems
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    • v.6 no.1
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    • pp.57-72
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    • 2010
  • This paper presents the most significant results obtained within a broad-ranging experimental program aiming to evaluate both the effectiveness and the robustness of a Base Isolation (BIS) and a Tuned Mass Damper (TMD) combined control strategy (BI & TMD). Following a brief description of the experimental model set-up and the adopted kinematic scaling technique, this paper describes the identification procedures carried out to characterize the system''s model. The dynamic response of a small-scale model to recorded earthquake excitations, which has been scaled by using the Buckingham pi-theorem, are later presented and discussed. Finally, the effectiveness and robustness of the combined control strategy is evaluated by comparing the model's dynamic response. In particular, reduction in relative displacements and absolute accelerations due to the application of different mass damping systems is investigated.

Characterization and Application of DLC Films Produced by New Combined PVD-CVD Technique

  • Chekan, N.M.;Kim, S.W.;Akula, I.P.;Jhee, T.G.
    • Journal of the Korean Society for Heat Treatment
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    • v.23 no.2
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    • pp.75-82
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    • 2010
  • A new advanced combined PVD/CVD technique of DLC film deposition has been developed. Deposition of a DLC film was carried out using a pulsed carbon arc discharge in vapor hydrocarbon atmosphere. The arc plasma enhancing CVD process promotes dramatic increase in the deposition rate and decrease of compressive stress as well as improvement of film thickness uniformity compared to that obtained with a single PVD pulsed arc process. The optical spectroscopy investigation reveals great increase in radiating components of $C_2$ Swan system molecular bands due to acetylene molecules decomposition. AFM, Raman spectroscopy, XPS and nano-indentation were used to characterize DLC films. The method ensures obtaining a new superhard DLC nano-material for deposition of protective coatings onto various industrial products including those used in medicine.

Remeshing techniques for r-adaptive and combined h/r-adaptive analysis with application to 2D/3D crack propagation

  • Askes, H.;Sluys, L.J.;de Jong, B.B.C.
    • Structural Engineering and Mechanics
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    • v.12 no.5
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    • pp.475-490
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    • 2001
  • Remeshing strategies are formulated for r-adaptive and h/r-adaptive analysis of crack propagation. The relocation of the nodes, which typifies r-adaptivity, is a very cheap method to optimise a given discretisation since the element connectivity remains unaltered. However, the applicability is limited. To further improve the finite element mesh, a combined h/r-adaptive method is proposed in which h-adaptivity is applied whenever r-adaptivity is not capable of further improving the discretisation. Two and three-dimensional examples are presented. It is shown that the r-adaptive approach can optimise a discretisation at minimal computational costs. Further, the combined h/r-adaptive approach improves the performance of a fully r-adaptive technique while the number of h-remeshings is reduced compared to a fully h-adaptive technique.

Transient Analysis and Evaluation of 345kV Combined Transmission Line Connected with GIL (345kV급 GIL이 연계된 혼합송전선로의 뇌서지해석 및 평가)

  • Jang, Hwa-Youn;Lee, Jong-Beom;Kim, Yong-Kap;Jung, Chae-Kyun
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.59 no.11
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    • pp.1949-1955
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    • 2010
  • This paper describes the characteristic and effectiveness of combined GIL transmission line through lightning surge analysis. In addition the XLPE cable is analyzed in the same condition to compare with GIL. Lighting surge analysis is carried out by EMTP/ATP-Draw to obtain overvoltage of GIL and XLPE cable at service-point and load-out area of underground line. Propagation velocity is calculated in combined transmission lines with GIL and XLPE cable. The overvoltage is also analyzed on GIL and XLPE cable with or without arrester operation. The Analysis results show that overvoltage of GIL is occurred higher than XLPE cable at the same condition. Therefore it is evaluated that the application of GIL at the field should be considered cautiously when more detailed transient analysis, another electrical testes and economic evaluations are implemented.

Theoretical Considerations on Combined Optical Distance Measurements Using a Femtosecond Pulse Laser

  • Joo, Ki-Nam;Kim, Seung-Woo
    • Journal of the Optical Society of Korea
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    • v.16 no.4
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    • pp.396-400
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    • 2012
  • We introduce a combined technique and the mathematical description for distance measurements using a femtosecond pulse laser in a long range and a fine resolution. For distance measurements, the maximum measurable range can be extended by combining measurement results from several different methods while requiring relationships between the different measurement uncertainties and unambiguity ranges. This paper briefly explains why the uncertainty of a rough measurement technique (RMT) should be, at least, smaller than the half unambiguity range of a fine measurement technique (FMT) in order to combine a FMT with a RMT. Further discussions about the total measurement range, resolution, and uncertainty for various optical measurement techniques are also discussed.