• The Journal of the Korea Contents Association
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• v.13 no.6
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• pp.339-349
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• 2013

This study was conducted to evaluate the correlation between the Korean version of Mini Mental State Examination (MMSE-K) and the Korean Computerized Neurobehavioral Test (KCNT) and the usefulness of KCNT for discriminating the patients with suspected dementia from normal persons in patients with a brain injury. The results of each items of KCNT had passed the test for normality. T test for group comparison and bivariate correlation analysis for correlation between two tests were used. There were no significant differences in characteristics of two groups. The differences in results of eight tests of KCNT between two groups were statistically significant (p<.05) and the Pearson correlation coefficients (r) between two tests were statistically significant (p<.05) : simple reaction time (-.580), choice reaction time (-.341), color word vigilance (-.661), digit classification (-.703), 2-digit addition (-.582), 3-digit addition (-.610), symbol digit substitution (-.642), and digit span (.807). These results suggested that simple reaction time and 2-digit addition were useful in discriminating the patients with suspected dementia from normal persons because the Pearson correlation coefficients of the two items of KCNT showed anticlastic association between two groups. And each items of KCNT may use in follow up cognitive function for patients in two groups.

• Journal of the Korean Society of Food Science and Nutrition
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• v.42 no.8
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• pp.1190-1196
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• 2013

The purpose of this study was to investigate the mechanism and effects of different types of ginseng on memory improvement in an experimental rat model. In this study, SD rats were induced for memory deficits through scopolamine treatment (1 mg/kg, i.p.) then administrated with ginseng extract for 7 weeks. The rats were divided into five groups: saline (1 mL/kg, NC: negative control), white ginseng (300 mg/kg, WG), red ginseng (300 mg/kg, RG), black ginseng (300 mg/kg, BG), and scopolamine (1 mg/kg, PC: positive control). The step through latency of the BG and RG groups was significantly longer than the PC group in the retention trial of multiple trial passive avoidance test. In the spatial reference memory triads of the Morris water maze test, the latency time of BG and RG was significantly lower than the PC group. In addition, in the prove test, the time spent in the platform quadrant of BG and RG groups were significantly longer than the PC group. Brain choline acetyltransferase (ChAT) activities BG and RG groups significantly increased compared to other groups. On the other hand, the levels of malondialdehyde (MDA) were significantly lower in the BG and RG groups compared to other groups. These result suggested that black ginseng could be useful to enhance learning memory and cognitive function by regulation of cholinergic enzymes.

• Journal of Platform Technology
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• v.6 no.4
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• pp.59-68
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• 2018

The objective of this study is to develop an embedded antenna structure with NFC and WPC composite functions. By selecting stable materials, the optimal component ratio of the polymer sheet was determined. The low cost embedded winding method compared to the existing FPCB was devised. During the winding process, characterization and process technology were developed. We also fabricated a ferrite mold to process the WPC grooves and developed the process technology for optimizing the WPC antenna. The following conclusions were obtained. (1) Optimum composition ratio was derived as Fe 87.5%, Si 7%, Al 5.5% and selected as the final material. (2) Optimal sheet conditions were derived from the experimental evaluation method and the experimental design method through the combination test of the optimized sheet and the conventional mass production FPCB. (3) According to coil diameter and inner diameter, Q value fluctuation, resistance value and efficiency fluctuation are obtained. Therefore, the most suitable coil condition is selected and Rx matching is performed. (4) The EMV load modulation test and the cognitive distance test of the polymer sheet and the ferrite sheet showed that the recognition distance of the polymer sheet at 1k and 4K was 32-33 mm and the recognition distance of the ferrite sheet at the same condition was 30-31 mm.

• Korean Journal of Clinical Laboratory Science
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• v.51 no.3
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• pp.351-359
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• 2019

Neurocognitive testing commonly uses the MMSE (Mini-Mental State Examination) to evaluate the overall cognitive function of patients at outpatient clinics, but the MMSE has recently been extensively used in the SNSB II (Seoul Neuropsychological Screening Battery II) for making diagnoses. We retrospectively investigated the results of routine neurocognitive tests and the results of the blood tests of 120 elderly patients who had been referred to a South Central Medical Center from 2017 to 2018 and who had been examined at a public health center. These subjects' space-time capability was high on the sub-region of the global deterioration scale (GDS). GDS showed a significant increase as the Na decreased on the electrolyte analysis. The subjects' concentration, their language-based orientation for space and time, their memory, and their scores for the frontal lobe function on GDS showed statistically significant reductions (P<0.001) For the normal and abnormal groups according to the ALT and creatinine levels, the frontal/execute function areas showed statistically significant differences (P<0.001) as well as negative correlation between GDS and ALT (P<0.01). In conclusion, this study provides basic information to develop test items that are important for patient screening and diagnosis, and several routine blood chemistry factors provide basic information for diagnosing and assessing the status and progress of cognitively impaired patients.

• Korean Journal of Cognitive Science
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• v.18 no.2
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• pp.113-138
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• 2007

The effects of schema on accurate and false memories of items in a scene were investigated in two experiments: Recognition of items in a scene was tested immediately in Experiment 1 and three days later in Experiment 2. In both experiments, the following three variables were manipulated: Exposure time (250ms or 10000ms), picture mode (completed pictures or scrambled pictures), and manipulation mode (missing item or substituted item). Experiment 1 had yielded three important results: First, although accurate memory for presented items got increased when the exposure time was longer, false memory of the critical lures was not changed. Second, false memory of critical lures in the missing condition, where there was not any conflict between verbatim information and gist information, was higher than that of the substituted condition, where verbatim information of the item that replaced the lure was in conflict with the gist information. Third, accurate memory for atypical items in the substituted rendition, which had replaced the critical lures and in conflict with the schema, was higher than that in the missing condition. In Experiment 2, recognition test were administered 72 hours after the participants saw the picture. The three effects mentioned in Experiment 1 had disappeared in Experiment 2. The results of Experiment 2 might be due to the selective weakening of verbatim information compared to the persistence of the gist (or schematic) information. The results of Experiments 1 and 2 showed that false memory of critical lures is more persistent than the accurate memory of non-critical information. Theoretical implications of the results were considered in terms of the function of the verbatim and gist information.

• Korean Journal of Clinical Laboratory Science
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• v.51 no.4
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• pp.397-405
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• 2019

Quantitative electroencephalography (QEEG) has been widely used in research and clinical fields. QEEG has been widely used to objectively document cerebral changes for the purpose of identifying the electrophysiological biomarkers across various clinical symptoms and for the stimulation of specific cortical regions associated with cognitive function. In electroencephalography (EEG), the difference in quantitative and qualitative analyses is discriminated not by its measurement methods and relevant clinical or research environments, but by its analysis methods. When performing a qualitative analysis, it is possible for a medical technologist or experienced researchers to read the EEG waveforms to exclude artifacts. However, the quantitative analysis is still based on mathematical modeling, and all EEG data are included for the analysis, leading the results to be affected by unexpected artifacts. In the hospital setting, the case that the medical technologists in charge of the EEG test perform academic research has been little reported, compared to other clinical physiological measurement-based research. This is because there are few laboratories specialized in clinical physiological research. In this respect, this study is expected to be utilized as a basic reference material for medical technologists, students, and academic researchers, all of whom would like to conduct a quantitative analysis.

• Journal of Korean Society of Forest Science
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• v.112 no.1
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• pp.93-104
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• 2023

Life expectancy is increasing due to the aging of the population, which is in turn exacerbating problems such as the prevalence of various geriatric diseases. This study was established to provide basic data for the expansion of forest healing activities for the elderly by systematically analyzing the literature on how such activities affect this age group. For the collection of studies, the Korean databases RISS, KISS, Korea Med, and Science On were used, while PubMed, Cochrane Central, MDPI, and Google Scholar were used to identify reports published elsewhere. To assess the quality of the methodology used in the collected studies, the risk of bias was analyzed using Cochrane's RoB2 and RoBANS. Among 1,856 reports initially identified, 21 were finally selected for analysis in this study, which were limited to research papers on forest healing activities for the elderly published between 2000 and January 2022. In this review, the subjects were those aged 60 or older, with a total of 750 participants, ranging from at least 7 to a maximum of 88 per study. The analysis showed that the most frequently performed tests in each category were on depression as a psychological indicator in 7 studies, MMSE(Mini Mental State Examination) as a cognitive indicator in 2 studies, on blood pressure as a physiological indicator in 4 studies, on melatonin as a biochemical indicator in 2 studies, and on body fat and muscle strength as physical indicators in 3 studies. Of the 21 studies, 19 used two or more test items, with psychological indicators being most commonly measured. For the future application of forest healing activities for the elderly, various forest healing programs to prevent cognitive function decline should be developed and distributed, and follow-up studies should be continuously presented to provide the basis for forest healing activities.

• Food Science and Biotechnology
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• v.17 no.3
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• pp.594-597
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• 2008

Natural products have been used to treat many neurological illnesses such as Alzheimer's disease. In the present study, the effects of the water extract of smoke-dried skipjack tuna (WSST), which is used as a traditional seasoning in Japan, as well as its fractions on acetylcholinesterase (AChE) inhibition in vitro and on memory in scopolamine-induced amnesia mice in vivo were evaluated. Bio-Rad P-2 gel permeation chromatography revealed the presence of 7 peaks and AChE significantly inhibited peak 3 and 5. When in vivo behavioral studies were conducted, a passive avoidance test revealed that treatment with 50 and 100 mg/kg WSST as well as with fraction 3 and 5 improved the loss in memory retention induced by scopolamine. These results suggest that skipjack tuna extract and its fractions improve memory deficits and that these substances are suitable for use in healthy foods designed to improve memory deficits induced by aging and Alzheimer's disease.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.8 no.3
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• pp.799-818
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• 2014

Spectrum sensing is a key technical challenge for cognitive radio (CR). It is well known that multi-cycle cyclostationarity (MC) detector is a powerful method for spectrum sensing. However, conventional MC detector is difficult to implement due to its high computational complexity. This paper pays attention to the fact that the computation complexity can be reduced by simplifying the test statistic of conventional MC detector. Based on this simplification process, an improved MC detector is proposed. Compared with the conventional one, the proposed detector has the low-computational complexity and sufficient-accuracy on sensing performance. Subsequently, the sensing performances are further investigated for the cases of Rayleigh, Nakagami-m, Rician, composite Rayleigh fading-lognormal shadowing and composite Nakagami fading-lognormal shadowing channels, respectively. Furthermore, the square-law combining (SLC) is introduced to improve the detection capability over fading-shadowing channels. The corresponding closed-form expressions of average detection probability are derived for each case by the moment generation function (MGF) approach. Finally, illustrative and analytical results show that the efficiency and reliability of proposed detector and the improvement on sensing performance by SLC over composite fading-shadowing channels.

• Journal of Korea Game Society
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• v.9 no.4
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• pp.45-56
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• 2009

It is necessary for young children to integrate the sense of sight, hearing, touch, etc. for developing their emotion and cognition. Thanks to Information and Communication Technology (ICT) development, young children have more opportunities to use various senses in learning process. However, ICT learning method is more focusing on the sense of sight and hearing, and lacks of integrated recognition and this fact leads to the reason why ICT can not be used as a main education tool. Therefore, this study evaluated the influence of wUbi-Pen(haptic device) on cognition using a computer puzzle program. The results show that young children using a haptic pen have greater intention and performance in object assembly, mazes, picture completion in K-WPPSI test than those of non-using haptic pen. This implies that haptic function should be considered in ICT material and indeed useful in various cognition-related symptoms and diseases.